Patient Portal

Zhifu Xiang, MD, PhD

Associate Professor, Medicine
Division of Hematology/Oncology

Specialty Areas

Hematology
Hematologic Malignancies
Medical Oncology

Board Certifications

Internal Medicine

Hospital Affiliations

Christian Hospital

Areas of Clinical Interest

Hematology Malignancies, benign hematology.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Christian Hospital

11125 Dunn Road
St. Louis, MO 63136

Suite: 100
Floor: 1
Office Phone: 314-362-7216

Education

Education

Fellowship, Hematology/Oncology: University of Arkansas for Medical Sciences. Little Rock, AR 2012
PhD, Hematology: Tongji Medical University, Wuhan, Hubei, China 1998
Medical Degree: Tongji Medical University, Wuhan, Hubei, China 1990

Publication & Research

Publication & Research

Imbalance of erythropoiesis and iron metabolism in patients with thalassemia.
Huang Y, Lei Y, Liu R, Liu J, Yang G, Xiang Z, Liang Y, Lai Y
Int J Med Sci. 2019; 16(2)302-310. doi: 10.7150/ijms.27829.

PMID:
    30745811
    [PubMed - in process]
Related citations


PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia.
Zhang J, Xiang Z, Malaviarachchi PA, Yan Y, Baltz NJ, Emanuel PD, Liu YL
Cell Signal. 2018 Oct; 5072-79. doi: 10.1016/j.cellsig.2018.06.004.

PMID:
    29964149
    [PubMed - in process]
Related citations


Image Diagnosis: Zinc-Induced Copper Deficiency Causing Pancytopenia Recognized on Bone Marrow Examination.
Johnsrud J, Abdallah AO, Schichman SA, Xiang Z
Perm J. 2017; 21pii: 16-077. doi: 10.7812/TPP/16-077.

PMID:
    28241910
    [PubMed - indexed for MEDLINE]
Related citations


Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy.
Liu YL, Yan Y, Webster C, Shao L, Lensing SY, Ni H, Feng W, Colorado N, Pathak R, Xiang Z, Hauer-Jensen M, Li S, Zhou D, Emanuel PD
Blood. 2016 Apr 14; 127(15)1912-22. doi: 10.1182/blood-2015-05-646216.

PMID:
    26764354
    [PubMed - indexed for MEDLINE]
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MYC amplification in multiple marker chromosomes and EZH2 microdeletion in a man with acute myeloid leukemia.
Xiang Z, Abdallah AO, Govindarajan R, Mehta P, Emanuel PD, Papenhausen P, Schichman SA
Cancer Genet. 2015 Mar; 208(3)96-100. doi: 10.1016/j.cancergen.2015.01.010.

PMID:
    25800664
    [PubMed - indexed for MEDLINE]
Related citations


A unique presentation of unilateral pleural effusion in a patient with a high-grade plasma cell neoplasm.
Abdallah AO, Bansal M, Kemp SA, Schichman SA, Xiang Z
Leuk Lymphoma. 2015; 56(10)2989-91. doi: 10.3109/10428194.2015.1016934.

PMID:
    25686646
    [PubMed - indexed for MEDLINE]
Related citations


Natural history of chronic myelomonocytic leukemia: gene sequencing identifies multiple clonal molecular abnormalities associated with rapid progression to acute myeloid leukemia.
Xiang Z, Kaur V, Aburiziq IK, Mehta P, Emanuel P, Schichman SA
Clin Case Rep. 2014 Dec; 2(6)265-70. doi: 10.1002/ccr3.110.

PMID:
    25548628
    [PubMed]
Related citations


Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression.
Wartman LD, Larson DE, Xiang Z, Ding L, Chen K, Lin L, Cahan P, Klco JM, Welch JS, Li C, Payton JE, Uy GL, Varghese N, Ries RE, Hoock M, Koboldt DC, McLellan MD, Schmidt H, Fulton RS, Abbott RM, Cook L, McGrath SD, Fan X, Dukes AF, Vickery T, Kalicki J, Lamprecht TL, Graubert TA, Tomasson MH, Mardis ER, Wilson RK, Ley TJ
J Clin Invest. 2011 Apr; 121(4)1445-55. doi: 10.1172/JCI45284.

PMID:
    21436584
    [PubMed - indexed for MEDLINE]
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CXCR4-mediated bone marrow progenitor cell maintenance and mobilization are modulated by c-kit activity.
Cheng M, Zhou J, Wu M, Boriboun C, Thorne T, Liu T, Xiang Z, Zeng Q, Tanaka T, Tang YL, Kishore R, Tomasson MH, Miller RJ, Losordo DW, Qin G
Circ Res. 2010 Oct 29; 107(9)1083-93. doi: 10.1161/CIRCRESAHA.110.220970.

PMID:
    20847314
    [PubMed - indexed for MEDLINE]
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Mcl1 haploinsufficiency protects mice from Myc-induced acute myeloid leukemia.
Xiang Z, Luo H, Payton JE, Cain J, Ley TJ, Opferman JT, Tomasson MH
J Clin Invest. 2010 Jun; 120(6)2109-18. doi: 10.1172/JCI39964.

PMID:
    20484815
    [PubMed - indexed for MEDLINE]
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Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia.
Tomasson MH, Xiang Z, Walgren R, Zhao Y, Kasai Y, Miner T, Ries RE, Lubman O, Fremont DH, McLellan MD, Payton JE, Westervelt P, DiPersio JF, Link DC, Walter MJ, Graubert TA, Watson M, Baty J, Heath S, Shannon WD, Nagarajan R, Bloomfield CD, Mardis ER, Wilson RK, Ley TJ
Blood. 2008 May 1; 111(9)4797-808. doi: 10.1182/blood-2007-09-113027.

PMID:
    18270328
    [PubMed - indexed for MEDLINE]
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Identification of somatic JAK1 mutations in patients with acute myeloid leukemia.
Xiang Z, Zhao Y, Mitaksov V, Fremont DH, Kasai Y, Molitoris A, Ries RE, Miner TL, McLellan MD, DiPersio JF, Link DC, Payton JE, Graubert TA, Watson M, Shannon W, Heath SE, Nagarajan R, Mardis ER, Wilson RK, Ley TJ, Tomasson MH
Blood. 2008 May 1; 111(9)4809-12.

PMID:
    18160671
    [PubMed - indexed for MEDLINE]
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Myeloproliferative disease induced by TEL-PDGFRB displays dynamic range sensitivity to Stat5 gene dosage.
Cain JA, Xiang Z, O'Neal J, Kreisel F, Colson A, Luo H, Hennighausen L, Tomasson MH
Blood. 2007 May 1; 109(9)3906-14.

PMID:
    17218386
    [PubMed - indexed for MEDLINE]
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Neoplasia driven by mutant c-KIT is mediated by intracellular, not plasma membrane, receptor signaling.
Xiang Z, Kreisel F, Cain J, Colson A, Tomasson MH
Mol Cell Biol. 2007 Jan; 27(1)267-82.

PMID:
    17060458
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Cancer genetics, immune therapy, cell therapy.