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William H. McAlister, MD

Professor, Radiology
Division of Diagnostic Radiology
Professor, Pediatrics

Specialty Areas

Pediatric Radiology
Diagnostic Radiology

Board Certifications

Radiology
Pediatric Radiology

Hospital Affiliations

Shriners Hospital for Children - St. Louis
Barnes-Jewish Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Bone and mineral research, bone and joint disorders, human genetics, skeletal dysplasias

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Education

Education

Residency-Fellowship: Radiology, Cincinnati General Hospital, Cincinnati, Ohio
Medical Degree: Wayne State University College of Medicine, Detroit, Michigan
BS: Wayne State University, Detroit, Michigan

Publication & Research

Publication & Research

Melorheostosis: Exome sequencing of an associated dermatosis implicates postzygotic mosaicism of mutated KRAS.
Whyte MP, Griffith M, Trani L, Mumm S, Gottesman GS, McAlister WH, Krysiak K, Lesurf R, Skidmore ZL, Campbell KM, Rosman IS, Bayliss S, Bijanki VN, Nenninger A, Van Tine BA, Griffith OL, Mardis ER
Bone. 2017 Aug; 101145-155. doi: 10.1016/j.bone.2017.04.010.

PMID:
    28434888
    [PubMed - in process]
Related citations


Raine Syndrome (OMIM #259775), Caused By FAM20C Mutation, Is Congenital Sclerosing Osteomalacia With Cerebral Calcification (OMIM 259660).
Whyte MP, McAlister WH, Fallon MD, Pierpont ME, Bijanki VN, Duan S, Otaify GA, Sly WS, Mumm S
J Bone Miner Res. 2017 Apr; 32(4)757-769. doi: 10.1002/jbmr.3034.

PMID:
    27862258
    [PubMed - indexed for MEDLINE]
Related citations


Asfotase alfa therapy for children with hypophosphatasia.
Whyte MP, Madson KL, Phillips D, Reeves AL, McAlister WH, Yakimoski A, Mack KE, Hamilton K, Kagan K, Fujita KP, Thompson DD, Moseley S, Odrljin T, Rockman-Greenberg C
JCI Insight. 2016 Jun 16; 1(9)e85971.

PMID:
    27699270
    [PubMed - in process]
Related citations


Skeletal Fluorosis Due To Inhalation Abuse of a Difluoroethane-Containing Computer Cleaner.
Tucci JR, Whitford GM, McAlister WH, Novack DV, Mumm S, Keaveny TM, Whyte MP
J Bone Miner Res. 2017 Jan; 32(1)188-195. doi: 10.1002/jbmr.2923.

PMID:
    27449958
    [PubMed - in process]
Related citations


Auricular ossification: A newly recognized feature of osteoprotegerin-deficiency juvenile Paget disease.
Gottesman GS, Madson KL, McAlister WH, Nenninger A, Wenkert D, Mumm S, Whyte MP
Am J Med Genet A. 2016 Apr; 170A(4)978-85. doi: 10.1002/ajmg.a.37536.

PMID:
    26762549
    [PubMed - indexed for MEDLINE]
Related citations


Congenital insensitivity to pain: Fracturing without apparent skeletal pathobiology caused by an autosomal dominant, second mutation in SCN11A encoding voltage-gated sodium channel 1.9.
Phatarakijnirund V, Mumm S, McAlister WH, Novack DV, Wenkert D, Clements KL, Whyte MP
Bone. 2016 Mar; 84289-98. doi: 10.1016/j.bone.2015.11.022.

PMID:
    26746779
    [PubMed - indexed for MEDLINE]
Related citations


Reply: Response to: Rapid Skeletal Turnover in a Radiographic Mimic of Osteopetrosis Might Be Secondary to Systemic Mastocytosis.
Whyte MP, Madson KL, McAlister WH, Mumm S, Novack DV, Blair JC, Shaw NJ
J Bone Miner Res. 2015 Aug; 30(8)1537. doi: 10.1002/jbmr.2561.

PMID:
    26183677
    [PubMed]
Related citations


Neonatal High Bone Mass With First Mutation of the NF-κB Complex: Heterozygous De Novo Missense (p.Asp512Ser) RELA (Rela/p65).
Frederiksen AL, Larsen MJ, Brusgaard K, Novack DV, Knudsen PJ, Schrøder HD, Qiu W, Eckhardt C, McAlister WH, Kassem M, Mumm S, Frost M, Whyte MP
J Bone Miner Res. 2016 Jan; 31(1)163-72. doi: 10.1002/jbmr.2590.

PMID:
    26178921
    [PubMed - indexed for MEDLINE]
Related citations


Hypophosphatasia: validation and expansion of the clinical nosology for children from 25 years experience with 173 pediatric patients.
Whyte MP, Zhang F, Wenkert D, McAlister WH, Mack KE, Benigno MC, Coburn SP, Wagy S, Griffin DM, Ericson KL, Mumm S
Bone. 2015 Jun; 75229-39. doi: 10.1016/j.bone.2015.02.022.

PMID:
    25731960
    [PubMed - indexed for MEDLINE]
Related citations


Response to: A rapid skeletal turnover in radiographic mimic of osteopetrosis might be secondary to systemic mastocytosis.
Whyte MP, Madson KL, McAlister WH, Mumm S, Novack DV, Blair JC, Shaw NJ
J Bone Miner Res. 2015 May; 30(5)946. doi: 10.1002/jbmr.2455.

PMID:
    25588359
    [PubMed - indexed for MEDLINE]
Related citations


Lenz-Majewski hyperostotic dwarfism with hyperphosphoserinuria from a novel mutation in PTDSS1 encoding phosphatidylserine synthase 1.
Whyte MP, Blythe A, McAlister WH, Nenninger AR, Bijanki VN, Mumm S
J Bone Miner Res. 2015 Apr; 30(4)606-14. doi: 10.1002/jbmr.2398.

PMID:
    25363158
    [PubMed - indexed for MEDLINE]
Related citations


Juvenile Paget's disease with heterozygous duplication within TNFRSF11A encoding RANK.
Whyte MP, Tau C, McAlister WH, Zhang X, Novack DV, Preliasco V, Santini-Araujo E, Mumm S
Bone. 2014 Nov; 68153-61. doi: 10.1016/j.bone.2014.07.019.

PMID:
    25063546
    [PubMed - indexed for MEDLINE]
Related citations


PHEX 3'-UTR c.*231A>G near the polyadenylation signal is a relatively common, mild, American mutation that masquerades as sporadic or X-linked recessive hypophosphatemic rickets.
Mumm S, Huskey M, Cajic A, Wollberg V, Zhang F, Madson KL, Wenkert D, McAlister WH, Gottesman GS, Whyte MP
J Bone Miner Res. 2015 Jan; 30(1)137-43. doi: 10.1002/jbmr.2307.

PMID:
    25042154
    [PubMed - indexed for MEDLINE]
Related citations


Optometric support to Pacific Angel--Nepal 2012.
McAlister WH, Wingert TA, Weaver JL, Gerber FE
Mil Med. 2014 Jul; 179(7)717-20. doi: 10.7205/MILMED-D-13-00560.

PMID:
    25003855
    [PubMed - indexed for MEDLINE]
Related citations


Multicentric carpotarsal osteolysis syndrome is caused by only a few domain-specific mutations in MAFB, a negative regulator of RANKL-induced osteoclastogenesis.
Mumm S, Huskey M, Duan S, Wenkert D, Madson KL, Gottesman GS, Nenninger AR, Laxer RM, McAlister WH, Whyte MP
Am J Med Genet A. 2014 Sep; 164A(9)2287-93. doi: 10.1002/ajmg.a.36641.

PMID:
    24989131
    [PubMed - indexed for MEDLINE]
Related citations


Rapid skeletal turnover in a radiographic mimic of osteopetrosis.
Whyte MP, Madson KL, Mumm S, McAlister WH, Novack DV, Blair JC, Helliwell TR, Stolina M, Abernethy LJ, Shaw NJ
J Bone Miner Res. 2014 Dec; 29(12)2601-9. doi: 10.1002/jbmr.2289.

PMID:
    24919763
    [PubMed - indexed for MEDLINE]
Related citations


Easier to swallow: pictorial review of structural findings of the pharynx at barium pharyngography.
Tao TY, Menias CO, Herman TE, McAlister WH, Balfe DM
Radiographics. 2013 Nov-Dec; 33(7)e189-208. doi: 10.1148/rg.337125153.

PMID:
    24224603
    [PubMed - indexed for MEDLINE]
Related citations


Panostotic expansile bone disease with massive jaw tumor formation and a novel mutation in the signal peptide of RANK.
Schafer AL, Mumm S, El-Sayed I, McAlister WH, Horvai AE, Tom AM, Hsiao EC, Schaefer FV, Collins MT, Anderson MS, Whyte MP, Shoback DM
J Bone Miner Res. 2014 Apr; 29(4)911-21. doi: 10.1002/jbmr.2094.

PMID:
    24014458
    [PubMed - indexed for MEDLINE]
Related citations


Juvenile paget's disease in an Iranian kindred with vitamin D deficiency and novel homozygous TNFRSF11B mutation.
Saki F, Karamizadeh Z, Nasirabadi S, Mumm S, McAlister WH, Whyte MP
J Bone Miner Res. 2013 Jun; 28(6)1501-8. doi: 10.1002/jbmr.1868.

PMID:
    23322328
    [PubMed - indexed for MEDLINE]
Related citations


Severe skeletal toxicity from protracted etidronate therapy for generalized arterial calcification of infancy.
Otero JE, Gottesman GS, McAlister WH, Mumm S, Madson KL, Kiffer-Moreira T, Sheen C, Millán JL, Ericson KL, Whyte MP
J Bone Miner Res. 2013 Feb; 28(2)419-30. doi: 10.1002/jbmr.1752.

PMID:
    22972716
    [PubMed - indexed for MEDLINE]
Related citations