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Faculty Physicians

William H. McAlister, MD

Professor, Radiology
Division of Diagnostic Radiology
Professor, Pediatrics

Specialty Areas

Pediatric Radiology
Diagnostic Radiology

Board Certifications

Radiology
Pediatric Radiology

Areas of Clinical Interest

Bone and mineral research, bone and joint disorders, human genetics, skeletal dysplasias

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Education

Education

Residency-Fellowship: Radiology, Cincinnati General Hospital, Cincinnati, Ohio
Medical Degree: Wayne State University College of Medicine, Detroit, Michigan
BS: Wayne State University, Detroit, Michigan

Publication & Research

Publication & Research

Response to: A rapid skeletal turnover in radiographic mimic of osteopetrosis might be secondary to systemic mastocytosis.
Whyte MP, Madson KL, McAlister WH, Mumm S, Novack DV, Blair JC, Shaw NJ
J Bone Miner Res. 2015 May; 30(5)946. doi: 10.1002/jbmr.2455.

PMID:
    25588359
    [PubMed - indexed for MEDLINE]
Related citations


Juvenile Paget's disease with heterozygous duplication within TNFRSF11A encoding RANK.
Whyte MP, Tau C, McAlister WH, Zhang X, Novack DV, Preliasco V, Santini-Araujo E, Mumm S
Bone. 2014 Nov; 68153-61. doi: 10.1016/j.bone.2014.07.019.

PMID:
    25063546
    [PubMed - indexed for MEDLINE]
Related citations


PHEX 3'-UTR c.*231A>G near the polyadenylation signal is a relatively common, mild, American mutation that masquerades as sporadic or X-linked recessive hypophosphatemic rickets.
Mumm S, Huskey M, Cajic A, Wollberg V, Zhang F, Madson KL, Wenkert D, McAlister WH, Gottesman GS, Whyte MP
J Bone Miner Res. 2015 Jan; 30(1)137-43. doi: 10.1002/jbmr.2307.

PMID:
    25042154
    [PubMed - indexed for MEDLINE]
Related citations


Multicentric carpotarsal osteolysis syndrome is caused by only a few domain-specific mutations in MAFB, a negative regulator of RANKL-induced osteoclastogenesis.
Mumm S, Huskey M, Duan S, Wenkert D, Madson KL, Gottesman GS, Nenninger AR, Laxer RM, McAlister WH, Whyte MP
Am J Med Genet A. 2014 Sep; 164A(9)2287-93. doi: 10.1002/ajmg.a.36641.

PMID:
    24989131
    [PubMed - indexed for MEDLINE]
Related citations


Rapid skeletal turnover in a radiographic mimic of osteopetrosis.
Whyte MP, Madson KL, Mumm S, McAlister WH, Novack DV, Blair JC, Helliwell TR, Stolina M, Abernethy LJ, Shaw NJ
J Bone Miner Res. 2014 Dec; 29(12)2601-9. doi: 10.1002/jbmr.2289.

PMID:
    24919763
    [PubMed - indexed for MEDLINE]
Related citations


Easier to swallow: pictorial review of structural findings of the pharynx at barium pharyngography.
Tao TY, Menias CO, Herman TE, McAlister WH, Balfe DM
Radiographics. 2013 Nov-Dec; 33(7)e189-208. doi: 10.1148/rg.337125153.

PMID:
    24224603
    [PubMed - indexed for MEDLINE]
Related citations


Panostotic expansile bone disease with massive jaw tumor formation and a novel mutation in the signal peptide of RANK.
Schafer AL, Mumm S, El-Sayed I, McAlister WH, Horvai AE, Tom AM, Hsiao EC, Schaefer FV, Collins MT, Anderson MS, Whyte MP, Shoback DM
J Bone Miner Res. 2014 Apr; 29(4)911-21. doi: 10.1002/jbmr.2094.

PMID:
    24014458
    [PubMed - indexed for MEDLINE]
Related citations


Juvenile paget's disease in an Iranian kindred with vitamin D deficiency and novel homozygous TNFRSF11B mutation.
Saki F, Karamizadeh Z, Nasirabadi S, Mumm S, McAlister WH, Whyte MP
J Bone Miner Res. 2013 Jun; 28(6)1501-8. doi: 10.1002/jbmr.1868.

PMID:
    23322328
    [PubMed - indexed for MEDLINE]
Related citations


Severe skeletal toxicity from protracted etidronate therapy for generalized arterial calcification of infancy.
Otero JE, Gottesman GS, McAlister WH, Mumm S, Madson KL, Kiffer-Moreira T, Sheen C, Millán JL, Ericson KL, Whyte MP
J Bone Miner Res. 2013 Feb; 28(2)419-30. doi: 10.1002/jbmr.1752.

PMID:
    22972716
    [PubMed - indexed for MEDLINE]
Related citations


Enzyme-replacement therapy in life-threatening hypophosphatasia.
Whyte MP, Greenberg CR, Salman NJ, Bober MB, McAlister WH, Wenkert D, Van Sickle BJ, Simmons JH, Edgar TS, Bauer ML, Hamdan MA, Bishop N, Lutz RE, McGinn M, Craig S, Moore JN, Taylor JW, Cleveland RH, Cranley WR, Lim R, Thacher TD, Mayhew JE, Downs M, Millán JL, Skrinar AM, Crine P, Landy H
N Engl J Med. 2012 Mar 8; 366(10)904-13. doi: 10.1056/NEJMoa1106173.

PMID:
    22397652
    [PubMed - indexed for MEDLINE]
Related citations


Hypophosphatasia: nonlethal disease despite skeletal presentation in utero (17 new cases and literature review).
Wenkert D, McAlister WH, Coburn SP, Zerega JA, Ryan LM, Ericson KL, Hersh JH, Mumm S, Whyte MP
J Bone Miner Res. 2011 Oct; 26(10)2389-98. doi: 10.1002/jbmr.454.

PMID:
    21713987
    [PubMed - indexed for MEDLINE]
Related citations


COL1 C-propeptide cleavage site mutations cause high bone mass osteogenesis imperfecta.
Lindahl K, Barnes AM, Fratzl-Zelman N, Whyte MP, Hefferan TE, Makareeva E, Brusel M, Yaszemski MJ, Rubin CJ, Kindmark A, Roschger P, Klaushofer K, McAlister WH, Mumm S, Leikin S, Kessler E, Boskey AL, Ljunggren O, Marini JC
Hum Mutat. 2011 Jun; 32(6)598-609. doi: 10.1002/humu.21475.

PMID:
    21344539
    [PubMed - indexed for MEDLINE]
Related citations


Dysosteosclerosis presents as an "osteoclast-poor" form of osteopetrosis: comprehensive investigation of a 3-year-old girl and literature review.
Whyte MP, Wenkert D, McAlister WH, Novack DV, Nenninger AR, Zhang X, Huskey M, Mumm S
J Bone Miner Res. 2010 Nov; 25(11)2527-39. doi: 10.1002/jbmr.131.

PMID:
    20499338
    [PubMed - indexed for MEDLINE]
Related citations


Elevated serum lactate dehydrogenase isoenzymes and aspartate transaminase distinguish Albers-Schönberg disease (Chloride Channel 7 Deficiency Osteopetrosis) among the sclerosing bone disorders.
Whyte MP, Kempa LG, McAlister WH, Zhang F, Mumm S, Wenkert D
J Bone Miner Res. 2010 Nov; 25(11)2515-26. doi: 10.1002/jbmr.130.

PMID:
    20499337
    [PubMed - indexed for MEDLINE]
Related citations


Chronic recurrent multifocal osteomyelitis mimicked in childhood hypophosphatasia.
Whyte MP, Wenkert D, McAlister WH, Mughal MZ, Freemont AJ, Whitehouse R, Baildam EM, Coburn SP, Ryan LM, Mumm S
J Bone Miner Res. 2009 Aug; 24(8)1493-505. doi: 10.1359/jbmr.090308.

PMID:
    19335222
    [PubMed - indexed for MEDLINE]
Related citations


Adenomyotic cyst of the uterus in an adolescent.
Ho ML, Raptis C, Hulett R, McAlister WH, Moran K, Bhalla S
Pediatr Radiol. 2008 Nov; 38(11)1239-42. doi: 10.1007/s00247-008-0948-0.

PMID:
    18679611
    [PubMed - indexed for MEDLINE]
Related citations


Bisphosphonate-induced osteopetrosis: novel bone modeling defects, metaphyseal osteopenia, and osteosclerosis fractures after drug exposure ceases.
Whyte MP, McAlister WH, Novack DV, Clements KL, Schoenecker PL, Wenkert D
J Bone Miner Res. 2008 Oct; 23(10)1698-707. doi: 10.1359/jbmr.080511.

PMID:
    18505375
    [PubMed - indexed for MEDLINE]
Related citations


Absence of MMP2 mutation in idiopathic multicentric osteolysis with nephropathy.
Wenkert D, Mumm S, Wiegand SM, McAlister WH, Whyte MP
Clin Orthop Relat Res. 2007 Sep; 46280-6.

PMID:
    17563705
    [PubMed - indexed for MEDLINE]
Related citations


Infantile hypophosphatasia: transplantation therapy trial using bone fragments and cultured osteoblasts.
Cahill RA, Wenkert D, Perlman SA, Steele A, Coburn SP, McAlister WH, Mumm S, Whyte MP
J Clin Endocrinol Metab. 2007 Aug; 92(8)2923-30.

PMID:
    17519318
    [PubMed - indexed for MEDLINE]
Related citations


Use of clinical practice guidelines by executive directors of optometric associations.
McAlister WH, Wingert TA, Weaver JL, Hanson HD, Amos JF
Optometry. 2006 Dec; 77(12)622-8.

PMID:
    17157243
    [PubMed - indexed for MEDLINE]
Related citations