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William Gerard Powderly, MD

J. William Campbell Professor of Medicine, Infectious Diseases
Director, Institute of Public Health
Director, Institute of Clinical and Translational Sciences

Specialty Areas

Infectious Diseases
HIV Medicine

Areas of Clinical Interest

Treatment of infectious diseases including HIV and AIDS, fungal infections

  • Education
  • Publication & Research
  • Financial Disclosures

Education

Education

MB, BCh, BAO: University College, Dublin, Ireland 1979
Fellowship, Infectious Diseases: Washington University School of Medicine, St. Louis, MO 1987
Residency, Registrar in Medicine: Mater Misericordiae Hospital, Dublin, Ireland 1983
Residency, Senior House Officer in Medicine: St. Vincent's Hospital, Dublin, Ireland 1982

Publication & Research

Publication & Research

COVID-19 and Outpatient Parenteral Antimicrobial Therapy: The Need to Protect Vulnerable Medicare Beneficiaries.
Hamad Y, Joynt Maddox KE, Powderly WG
Ann Intern Med. 2020 May 13; doi: 10.7326/M20-1774.

PMID:
    32422072
    [PubMed - as supplied by publisher]
Related citations


Integrase Strand Transfer Inhibitors are associated with lower risk of incident Cardiovascular Disease in People Living with HIV.
O'Halloran JA, Sahrmann J, Butler AM, Olsen MA, Powderly WG
J Acquir Immune Defic Syndr. 2020 Mar 25; doi: 10.1097/QAI.0000000000002357.

PMID:
    32243280
    [PubMed - as supplied by publisher]
Related citations


Infectious disease consultation for candidaemia - Authors' reply.
Mejia-Chew C, O'Halloran JA, Olsen MA, Stwalley D, Salter A, Powderly WG, Spec A
Lancet Infect Dis. 2020 Feb; 20(2)165-166. doi: 10.1016/S1473-3099(20)30005-0.

PMID:
    32006500
    [PubMed - in process]
Related citations


Risk factors predicting Candida infective endocarditis in patients with candidemia.
Foong KS, Sung A, Burnham JP, Kronen R, Lian Q, Salazar Zetina A, Hsueh K, Lin C, Powderly WG, Spec A
Med Mycol. 2019 Oct 15; pii: myz104. doi: 10.1093/mmy/myz104.

PMID:
    31613365
    [PubMed - as supplied by publisher]
Related citations


Effect of infectious disease consultation on mortality and treatment of patients with candida bloodstream infections: a retrospective, cohort study.
Mejia-Chew C, O'Halloran JA, Olsen MA, Stwalley D, Kronen R, Lin C, Salazar AS, Larson L, Hsueh K, Powderly WG, Spec A
Lancet Infect Dis. 2019 Dec; 19(12)1336-1344. doi: 10.1016/S1473-3099(19)30405-0.

PMID:
    31562024
    [PubMed - in process]
Related citations


Designing for Accelerated Translation (DART) of Emerging Innovations in Health.
Ramsey AT, Proctor EK, Chambers DA, Garbutt JM, Malone S, Powderly WG, Bierut LJ
J Clin Transl Sci. 2019 Jun; 3(2-3)53-58. doi: 10.1017/cts.2019.386.

PMID:
    31528365
    [PubMed]
Related citations


HOW INFECTION SHAPED HISTORY: LESSONS FROM THE IRISH FAMINE.
Powderly WG
Trans Am Clin Climatol Assoc. 2019; 130127-135.

PMID:
    31516176
    [PubMed - indexed for MEDLINE]
Related citations


The Importance of Inclusion, Diversity, and Equity to the Future of the Infectious Diseases Society of America.
Powderly WG
J Infect Dis. 2019 Aug 20; 220(220 Suppl 2)S82-S85. doi: 10.1093/infdis/jiz197.

PMID:
    31430378
    [PubMed - indexed for MEDLINE]
Related citations


Mortality After Cryptococcal Infection in the Modern Antiretroviral Therapy Era.
Hevey MA, Presti RM, OʼHalloran JA, Larson L, Raval K, Powderly WG, Spec A
J Acquir Immune Defic Syndr. 2019 Sep 1; 82(1)81-87. doi: 10.1097/QAI.0000000000002095.

PMID:
    31408451
    [PubMed - indexed for MEDLINE]
Related citations


MSG-10: a Phase 2 study of oral ibrexafungerp (SCY-078) following initial echinocandin therapy in non-neutropenic patients with invasive candidiasis.
Spec A, Pullman J, Thompson GR, Powderly WG, Tobin EH, Vazquez J, Wring SA, Angulo D, Helou S, Pappas PG, Mycoses Study Group.
J Antimicrob Chemother. 2019 Oct 1; 74(10)3056-3062. doi: 10.1093/jac/dkz277.

PMID:
    31304536
    [PubMed - in process]
Related citations


Presentation and Mortality of Cryptococcal Infection Varies by Predisposing Illness: A Retrospective Cohort Study.
Hevey MA, George IA, Raval K, Powderly WG, Spec A
Am J Med. 2019 Aug; 132(8)977-983.e1. doi: 10.1016/j.amjmed.2019.04.026.

PMID:
    31077652
    [PubMed - indexed for MEDLINE]
Related citations


Creation and assessment of a clinical predictive model for candidaemia in patients with candiduria.
Wang K, Hsueh K, Kronen R, Lin C, Salazar AS, Powderly WG, Spec A
Mycoses. 2019 Jul; 62(7)554-561. doi: 10.1111/myc.12917.

PMID:
    31025417
    [PubMed - indexed for MEDLINE]
Related citations


Reply.
Lok AS, Powderly WG
Hepatology. 2019 May; 69(5)2301. doi: 10.1002/hep.30564.

PMID:
    30762891
    [PubMed - indexed for MEDLINE]
Related citations


EQUAL <i>Cryptococcus</i> Score 2018: A <i>E</i>uropean Confederation of Medical Mycology Score Derived From Current Guidelines to Measure <i>QUAL</i>ity of Clinical Cryptococcosis Management.
Spec A, Mejia-Chew C, Powderly WG, Cornely OA
Open Forum Infect Dis. 2018 Nov; 5(11)ofy299. doi: 10.1093/ofid/ofy299.

PMID:
    30515434
    [PubMed]
Related citations


Late Presentation and Missed Opportunities for HIV Diagnosis in Guatemala.
Meléndez J, Reinhardt SW, O'Halloran JA, Spec A, Alonzo Cordon A, Powderly WG, Mejia Villatoro C
AIDS Behav. 2019 Apr; 23(4)920-928. doi: 10.1007/s10461-018-2331-y.

PMID:
    30426264
    [PubMed - indexed for MEDLINE]
Related citations


Comfort Discussing HIV Pre-exposure Prophylaxis With Patients Among Physicians in an Urban Emergency Department.
Tortelli BA, Char DM, Crane JS, Powderly WG, Salter A, Chan PA, Patel RR
J Acquir Immune Defic Syndr. 2019 Feb 1; 80(2)e49-e52. doi: 10.1097/QAI.0000000000001890.

PMID:
    30422901
    [PubMed - indexed for MEDLINE]
Related citations


Missed Opportunities to Prescribe HIV Pre-Exposure Prophylaxis by Primary Care Providers in Saint Louis, Missouri.
Patel RR, Chan PA, Harrison LC, Mayer KH, Nunn A, Mena LA, Powderly WG
LGBT Health. 2018 May/Jun; 5(4)250-256. doi: 10.1089/lgbt.2017.0101.

PMID:
    29688800
    [PubMed - indexed for MEDLINE]
Related citations


Cryptococcal meningitis in AIDS.
Spec A, Powderly WG
Handb Clin Neurol. 2018; 152139-150. doi: 10.1016/B978-0-444-63849-6.00011-6.

PMID:
    29604972
    [PubMed - indexed for MEDLINE]
Related citations


Creation and Assessment of a Clinical Predictive Calculator and Mortality Associated With <i>Candida krusei</i> Bloodstream Infections.
Kronen R, Hsueh K, Lin C, Powderly WG, Spec A
Open Forum Infect Dis. 2018 Feb; 5(2)ofx253. doi: 10.1093/ofid/ofx253.

PMID:
    29450209
    [PubMed]
Related citations


Sex Venue-Based Network Analysis to Identify HIV Prevention Dissemination Targets for Men Who Have Sex with Men.
Patel RR, Luke DA, Proctor EK, Powderly WG, Chan PA, Mayer KH, Harrison LC, Dhand A
LGBT Health. 2018 Jan; 5(1)78-85. doi: 10.1089/lgbt.2017.0018.

PMID:
    29324178
    [PubMed - indexed for MEDLINE]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians and health professionals are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians and health professionals work collaboratively with pharmaceutical, medical device or other medical care related companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our physicians and health professionals have an ownership or potential ownership interest in a commercial company; and/or are paid by a commercial company to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians or health professionals must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this website, physicians and health professionals earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following financial interests during calendar year 2019:

Company Name: Gilead

Royalties:

Equity: No

Consulting/Advisory Board: $10,000 - $19,999

Speaker Fees:

Reporting Date: May 01, 2020

Areas of Research Interest

Improving treatments for patients with HIV; understanding long-term side effects of HIV medications, particularly metabolic problems such as diabetes, lipid abnormalities, and osteoporosis.