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William Gerard Powderly, MD

J. William Campbell Professor of Medicine, Infectious Diseases
Director, Institute of Public Health

Specialty Areas

Infectious Diseases
HIV Medicine

Areas of Clinical Interest

Treatment of infectious diseases including HIV and AIDS, fungal infections

  • Education
  • Publication & Research
  • Financial Disclosures

Education

Education

MB, BCh, BAO: University College, Dublin, Ireland 1979
Fellowship, Infectious Diseases: Washington University School of Medicine, St. Louis, MO 1987
Residency, Registrar in Medicine: Mater Misericordiae Hospital, Dublin, Ireland 1983
Residency, Senior House Officer in Medicine: St. Vincent's Hospital, Dublin, Ireland 1982

Publication & Research

Publication & Research

Sex Venue-Based Network Analysis to Identify HIV Prevention Dissemination Targets for Men Who Have Sex with Men.
Patel RR, Luke DA, Proctor EK, Powderly WG, Chan PA, Mayer KH, Harrison LC, Dhand A
LGBT Health. 2018 Jan; 5(1)78-85. doi: 10.1089/lgbt.2017.0018.

PMID:
    29324178
    [PubMed - in process]
Related citations


AIDS-Defining Illnesses at Initial Diagnosis of HIV in a Large Guatemalan Cohort.
Reinhardt SW, Spec A, Meléndez J, Alonzo Cordon A, Ross I, Powderly WG, Mejia Villatoro C
Open Forum Infect Dis. 2017 Fall; 4(4)ofx249. doi: 10.1093/ofid/ofx249.

PMID:
    29308405
    [PubMed]
Related citations


Tenofovir disoproxil fumarate as pre-exposure prophylaxis for HIV prevention in women with osteoporosis: a case report and review of the literature.
Patel RR, Presti R, Harrison LC, Powderly WG, Chan PA
Antivir Ther. 2017 Nov 23; doi: 10.3851/IMP3208.

PMID:
    29168695
    [PubMed - as supplied by publisher]
Related citations


Understanding mechanisms to promote successful aging in persons living with HIV.
Escota GV, O'Halloran JA, Powderly WG, Presti RM
Int J Infect Dis. 2018 Jan; 6656-64. doi: 10.1016/j.ijid.2017.11.010.

PMID:
    29154830
    [PubMed - in process]
Related citations


Cryptococcosis today: It is not all about HIV infection.
O'Halloran JA, Powderly WG, Spec A
Curr Clin Microbiol Rep. 2017 Jun; 4(2)88-95. doi: 10.1007/s40588-017-0064-8.

PMID:
    29130027
    [PubMed]
Related citations


Benefits of Direct-Acting Antivirals for Hepatitis C.
Lok AS, Chung RT, Vargas HE, Kim AY, Naggie S, Powderly WG
Ann Intern Med. 2017 Dec 5; 167(11)812-813. doi: 10.7326/M17-1876.

PMID:
    29049502
    [PubMed - indexed for MEDLINE]
Related citations


Comparative Epidemiology and Outcomes of HIV, Non-HIV Non-Transplant and Organ Transplant Associated Cryptococcosis: A Population-Based Study.
George IA, Spec A, Powderly WG, Santos CAQ
Clin Infect Dis. 2017 Oct 4; doi: 10.1093/cid/cix867.

PMID:
    29028978
    [PubMed - as supplied by publisher]
Related citations


IDSA/AASLD Response to Cochrane Review on Direct-Acting Antivirals for Hepatitis C.
Powderly WG, Naggie S, Kim AY, Vargas HE, Chung RT, Lok AS
Clin Infect Dis. 2017 Nov 13; 65(11)1773-1775. doi: 10.1093/cid/cix620.

PMID:
    29020156
    [PubMed - in process]
Related citations


Proposed U.S. Funding Cuts Threaten Progress on Antimicrobial Resistance.
Boucher HW, Murray BE, Powderly WG
Ann Intern Med. 2017 Nov 21; 167(10)738-739. doi: 10.7326/M17-1678.

PMID:
    28869976
    [PubMed - indexed for MEDLINE]
Related citations


Comments on cochrane review on direct-acting antivirals for hepatitis C.
Lok AS, Chung RT, Vargas HE, Kim AY, Naggie S, Powderly WG
Hepatology. 2017 Oct; 66(4)1016-1019. doi: 10.1002/hep.29366.

PMID:
    28714142
    [PubMed - in process]
Related citations


Invasive Fungal Infections Secondary to Traumatic Injury.
Kronen R, Liang SY, Bochicchio G, Bochicchio K, Powderly WG, Spec A
Int J Infect Dis. 2017 Sep; 62102-111. doi: 10.1016/j.ijid.2017.07.002.

PMID:
    28705753
    [PubMed - in process]
Related citations


Conflicts of Interest Reported in an Abbreviated Time Frame.
Lok AS, Powderly WG
JAMA Intern Med. 2017 Jul 1; 177(7)1059-1060. doi: 10.1001/jamainternmed.2017.2244.

PMID:
    28672362
    [PubMed - in process]
Related citations


Epidemiology of Cryptococcosis and Cryptococcal Meningitis in a Large Retrospective Cohort of Patients After Solid Organ Transplantation.
George IA, Santos CAQ, Olsen MA, Powderly WG
Open Forum Infect Dis. 2017 Winter; 4(1)ofx004. doi: 10.1093/ofid/ofx004.

PMID:
    28480277
    [PubMed]
Related citations


HIV and its relationship to insulin resistance and lipid abnormalities.
Non LR, Escota GV, Powderly WG
Transl Res. 2017 May; 18341-56. doi: 10.1016/j.trsl.2016.12.007.

PMID:
    28068521
    [PubMed - indexed for MEDLINE]
Related citations


Impact of Infectious Diseases Consultation on Mortality of Cryptococcal infection in Patients without HIV.
Spec A, Olsen MA, Raval K, Powderly WG
Clin Infect Dis. 2017 Mar 1; 64(5)558-564. doi: 10.1093/cid/ciw786.

PMID:
    27927865
    [PubMed - as supplied by publisher]
Related citations


Concurrent Ramsay Hunt syndrome and disseminated herpes zoster in a patient with relapsed chronic lymphocytic leukemia.
Chen I, Fohtung RB, Oughli HA, Bauer R, Mattar C, Powderly WG, Thoelke MS
IDCases. 2016; 679-82.

PMID:
    27757380
    [PubMed]
Related citations


Association of serum albumin and aspartate transaminase with 5-year all-cause mortality in HIV/hepatitis C virus coinfection and HIV monoinfection.
Scherzer R, Heymsfield SB, Rimland D, Powderly WG, Tien PC, Bacchetti P, Shlipak MG, Grunfeld C, Study of Fat Redistribution, Metabolic Change in HIV Infection (FRAM).
AIDS. 2017 Jan 2; 31(1)71-79.

PMID:
    27677166
    [PubMed - indexed for MEDLINE]
Related citations


Diabetes Mellitus is Associated With Higher Risk of Developing Decompensated Cirrhosis in Chronic Hepatitis C Patients.
Saeed MJ, Olsen MA, Powderly WG, Presti RM
J Clin Gastroenterol. 2017 Jan; 51(1)70-76.

PMID:
    27306942
    [PubMed - indexed for MEDLINE]
Related citations


End-Stage Liver Disease Is a Strong Predictor of Early Mortality in Cryptococcosis.
Spec A, Raval K, Powderly WG
Open Forum Infect Dis. 2016 Jan; 3(1)ofv197. doi: 10.1093/ofid/ofv197.

PMID:
    26835475
    [PubMed]
Related citations


Target prices for mass production of tyrosine kinase inhibitors for global cancer treatment.
Hill A, Gotham D, Fortunak J, Meldrum J, Erbacher I, Martin M, Shoman H, Levi J, Powderly WG, Bower M
BMJ Open. 2016 Jan 27; 6(1)e009586. doi: 10.1136/bmjopen-2015-009586.

PMID:
    26817636
    [PubMed - indexed for MEDLINE]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2016.

Company Name: Gilead

Royalties:

Equity: No

Consulting/Advisory Board: $10,001 - $25,000

Speaker Fees:

Reporting Date: May 01, 2017

Areas of Research Interest

Improving treatments for patients with HIV; understanding long-term side effects of HIV medications, particularly metabolic problems such as diabetes, lipid abnormalities, and osteoporosis.