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William Gerard Powderly, MD

J. William Campbell Professor of Medicine, Infectious Diseases
Director, Institute of Public Health

Specialty Areas

Infectious Diseases
HIV Medicine

Areas of Clinical Interest

Treatment of infectious diseases including HIV and AIDS, fungal infections

  • Education
  • Publication & Research

Education

Education

MB, BCh, BAO: University College, Dublin, Ireland 1979
Fellowship, Infectious Diseases: Washington University School of Medicine, St. Louis, MO 1987
Residency, Registrar in Medicine: Mater Misericordiae Hospital, Dublin, Ireland 1983
Residency, Senior House Officer in Medicine: St. Vincent's Hospital, Dublin, Ireland 1982

Publication & Research

Publication & Research

EQUAL <i>Cryptococcus</i> Score 2018: A <i>E</i>uropean Confederation of Medical Mycology Score Derived From Current Guidelines to Measure <i>QUAL</i>ity of Clinical Cryptococcosis Management.
Spec A, Mejia-Chew C, Powderly WG, Cornely OA
Open Forum Infect Dis. 2018 Nov; 5(11)ofy299. doi: 10.1093/ofid/ofy299.

PMID:
    30515434
    [PubMed]
Related citations


Late Presentation and Missed Opportunities for HIV Diagnosis in Guatemala.
Meléndez J, Reinhardt SW, O'Halloran JA, Spec A, Alonzo Cordon A, Powderly WG, Mejia Villatoro C
AIDS Behav. 2018 Nov 13; doi: 10.1007/s10461-018-2331-y.

PMID:
    30426264
    [PubMed - as supplied by publisher]
Related citations


Comfort discussing HIV pre-exposure prophylaxis with patients among physicians in an urban emergency department.
Tortelli BA, Char DM, Crane JS, Powderly WG, Salter A, Chan PA, Patel RR
J Acquir Immune Defic Syndr. 2018 Nov 5; doi: 10.1097/QAI.0000000000001890.

PMID:
    30422901
    [PubMed - as supplied by publisher]
Related citations


Missed Opportunities to Prescribe HIV Pre-Exposure Prophylaxis by Primary Care Providers in Saint Louis, Missouri.
Patel RR, Chan PA, Harrison LC, Mayer KH, Nunn A, Mena LA, Powderly WG
LGBT Health. 2018 May/Jun; 5(4)250-256. doi: 10.1089/lgbt.2017.0101.

PMID:
    29688800
    [PubMed - in process]
Related citations


Cryptococcal meningitis in AIDS.
Spec A, Powderly WG
Handb Clin Neurol. 2018; 152139-150. doi: 10.1016/B978-0-444-63849-6.00011-6.

PMID:
    29604972
    [PubMed - indexed for MEDLINE]
Related citations


Creation and Assessment of a Clinical Predictive Calculator and Mortality Associated With <i>Candida krusei</i> Bloodstream Infections.
Kronen R, Hsueh K, Lin C, Powderly WG, Spec A
Open Forum Infect Dis. 2018 Feb; 5(2)ofx253. doi: 10.1093/ofid/ofx253.

PMID:
    29450209
    [PubMed]
Related citations


Sex Venue-Based Network Analysis to Identify HIV Prevention Dissemination Targets for Men Who Have Sex with Men.
Patel RR, Luke DA, Proctor EK, Powderly WG, Chan PA, Mayer KH, Harrison LC, Dhand A
LGBT Health. 2018 Jan; 5(1)78-85. doi: 10.1089/lgbt.2017.0018.

PMID:
    29324178
    [PubMed - in process]
Related citations


AIDS-Defining Illnesses at Initial Diagnosis of HIV in a Large Guatemalan Cohort.
Reinhardt SW, Spec A, Meléndez J, Alonzo Cordon A, Ross I, Powderly WG, Mejia Villatoro C
Open Forum Infect Dis. 2017 Fall; 4(4)ofx249. doi: 10.1093/ofid/ofx249.

PMID:
    29308405
    [PubMed]
Related citations


Tenofovir disoproxil fumarate as pre-exposure prophylaxis for HIV prevention in women with osteoporosis: a case report and review of the literature.
Patel RR, Presti R, Harrison LC, Powderly WG, Chan PA
Antivir Ther. 2018; 23(4)379-382. doi: 10.3851/IMP3208.

PMID:
    29168695
    [PubMed - in process]
Related citations


Understanding mechanisms to promote successful aging in persons living with HIV.
Escota GV, O'Halloran JA, Powderly WG, Presti RM
Int J Infect Dis. 2018 Jan; 6656-64. doi: 10.1016/j.ijid.2017.11.010.

PMID:
    29154830
    [PubMed - indexed for MEDLINE]
Related citations


Cryptococcosis today: It is not all about HIV infection.
O'Halloran JA, Powderly WG, Spec A
Curr Clin Microbiol Rep. 2017 Jun; 4(2)88-95. doi: 10.1007/s40588-017-0064-8.

PMID:
    29130027
    [PubMed]
Related citations


Benefits of Direct-Acting Antivirals for Hepatitis C.
Lok AS, Chung RT, Vargas HE, Kim AY, Naggie S, Powderly WG
Ann Intern Med. 2017 Dec 5; 167(11)812-813. doi: 10.7326/M17-1876.

PMID:
    29049502
    [PubMed - indexed for MEDLINE]
Related citations


Comparative Epidemiology and Outcomes of Human Immunodeficiency virus (HIV), Non-HIV Non-transplant, and Solid Organ Transplant Associated Cryptococcosis: A Population-Based Study.
George IA, Spec A, Powderly WG, Santos CAQ
Clin Infect Dis. 2018 Feb 1; 66(4)608-611. doi: 10.1093/cid/cix867.

PMID:
    29028978
    [PubMed - in process]
Related citations


IDSA/AASLD Response to Cochrane Review on Direct-Acting Antivirals for Hepatitis C.
Powderly WG, Naggie S, Kim AY, Vargas HE, Chung RT, Lok AS
Clin Infect Dis. 2017 Nov 13; 65(11)1773-1775. doi: 10.1093/cid/cix620.

PMID:
    29020156
    [PubMed - in process]
Related citations


Proposed U.S. Funding Cuts Threaten Progress on Antimicrobial Resistance.
Boucher HW, Murray BE, Powderly WG
Ann Intern Med. 2017 Nov 21; 167(10)738-739. doi: 10.7326/M17-1678.

PMID:
    28869976
    [PubMed - indexed for MEDLINE]
Related citations


Comments on cochrane review on direct-acting antivirals for hepatitis C.
Lok AS, Chung RT, Vargas HE, Kim AY, Naggie S, Powderly WG
Hepatology. 2017 Oct; 66(4)1016-1019. doi: 10.1002/hep.29366.

PMID:
    28714142
    [PubMed - indexed for MEDLINE]
Related citations


Invasive Fungal Infections Secondary to Traumatic Injury.
Kronen R, Liang SY, Bochicchio G, Bochicchio K, Powderly WG, Spec A
Int J Infect Dis. 2017 Sep; 62102-111. doi: 10.1016/j.ijid.2017.07.002.

PMID:
    28705753
    [PubMed - indexed for MEDLINE]
Related citations


Conflicts of Interest Reported in an Abbreviated Time Frame.
Lok AS, Powderly WG
JAMA Intern Med. 2017 Jul 1; 177(7)1059-1060. doi: 10.1001/jamainternmed.2017.2244.

PMID:
    28672362
    [PubMed - in process]
Related citations


Epidemiology of Cryptococcosis and Cryptococcal Meningitis in a Large Retrospective Cohort of Patients After Solid Organ Transplantation.
George IA, Santos CAQ, Olsen MA, Powderly WG
Open Forum Infect Dis. 2017 Winter; 4(1)ofx004. doi: 10.1093/ofid/ofx004.

PMID:
    28480277
    [PubMed]
Related citations


HIV and its relationship to insulin resistance and lipid abnormalities.
Non LR, Escota GV, Powderly WG
Transl Res. 2017 May; 18341-56. doi: 10.1016/j.trsl.2016.12.007.

PMID:
    28068521
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Improving treatments for patients with HIV; understanding long-term side effects of HIV medications, particularly metabolic problems such as diabetes, lipid abnormalities, and osteoporosis.