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William Frederick Stenson, MD

Dr. Nicholas V. Costrini Professor of Gastroenterology & Inflammatory Bowel Disease, Division of Gastroenterology

Specialty Areas

Gastroenterology
Inflammatory Bowel Disease
Gastrointestinal Oncology

Board Certifications

Internal Medicine
Gastroenterology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Gastroenterology, inflammatory bowel disease, ulcerative colitis, Crohn’s disease, celiac disease

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Gastrointestinal Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 8
Office Phone: 314-747-3969
Fax: 314-362-9035

Education

Education

Fellowship: Gastroenterology, Washington University School of Medicine, St Louis, Missouri 1978
Residency: Internal Medicine, Barnes-Jewish Hospital, St. Louis, Missouri 1976
Medical Degree: Washington University School of Medicine, St Louis, Missouri 1971
B.S.: Providence College, Providence, Rhode Island 1967

Publication & Research

Publication & Research

Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse.
Schill EM, Lake JI, Tusheva OA, Nagy N, Bery SK, Foster L, Avetisyan M, Johnson SL, Stenson WF, Goldstein AM, Heuckeroth RO
Dev Biol. 2016 Jan 15; 409(2)473-88. doi: 10.1016/j.ydbio.2015.09.023.

PMID:
    26586201
    [PubMed - in process]
Related citations


CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5+ stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice.
Riehl TE, Santhanam S, Foster L, Ciorba M, Stenson WF
Am J Physiol Gastrointest Liver Physiol. 2015 Dec 1; 309(11)G874-87. doi: 10.1152/ajpgi.00123.2015.

PMID:
    26505972
    [PubMed - indexed for MEDLINE]
Related citations


Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis.
Hannan TJ, Roberts PL, Riehl TE, van der Post S, Binkley JM, Schwartz DJ, Miyoshi H, Mack M, Schwendener RA, Hooton TM, Stappenbeck TS, Hansson GC, Stenson WF, Colonna M, Stapleton AE, Hultgren SJ
EBioMedicine. 2014 Nov; 1(1)46-57. doi: 10.1016/j.ebiom.2014.10.011.

PMID:
    26125048
    [PubMed]
Related citations


Probiotics to prevent gastrointestinal toxicity from cancer therapy: an interpretive review and call to action.
Ciorba MA, Hallemeier CL, Stenson WF, Parikh PJ
Curr Opin Support Palliat Care. 2015 Jun; 9(2)157-62. doi: 10.1097/SPC.0000000000000134.

PMID:
    25872116
    [PubMed - indexed for MEDLINE]
Related citations


Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice.
Shen Y, Ma J, Yan R, Ling H, Li X, Yang W, Gao J, Huang C, Bu Y, Cao Y, He Y, Wan L, Zu X, Liu J, Huang MC, Stenson WF, Liao DF, Cao D
Clin Cancer Res. 2015 Mar 15; 21(6)1466-76. doi: 10.1158/1078-0432.CCR-14-2072.

PMID:
    25538260
    [PubMed - indexed for MEDLINE]
Related citations


Variation in treatment of patients with inflammatory bowel diseases at major referral centers in the United States.
Ananthakrishnan AN, Kwon J, Raffals L, Sands B, Stenson WF, McGovern D, Kwon JH, Rheaume RL, Sandler RS
Clin Gastroenterol Hepatol. 2015 Jun; 13(6)1197-200. doi: 10.1016/j.cgh.2014.11.020.

PMID:
    25460565
    [PubMed - indexed for MEDLINE]
Related citations


The universe of arachidonic acid metabolites in inflammatory bowel disease: can we tell the good from the bad?
Stenson WF
Curr Opin Gastroenterol. 2014 Jul; 30(4)347-51. doi: 10.1097/MOG.0000000000000075.

PMID:
    24837228
    [PubMed - indexed for MEDLINE]
Related citations


IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice.
Thaker AI, Rao MS, Bishnupuri KS, Kerr TA, Foster L, Marinshaw JM, Newberry RD, Stenson WF, Ciorba MA
Gastroenterology. 2013 Aug; 145(2)416-25.e1-4. doi: 10.1053/j.gastro.2013.05.002.

PMID:
    23669411
    [PubMed - indexed for MEDLINE]
Related citations


Preventing necrotising enterocolitis with amniotic fluid stem cells.
Stenson WF
Gut. 2014 Feb; 63(2)218-9. doi: 10.1136/gutjnl-2013-304653.

PMID:
    23616579
    [PubMed - indexed for MEDLINE]
Related citations


The hyaluronic acid receptor CD44 coordinates normal and metaplastic gastric epithelial progenitor cell proliferation.
Khurana SS, Riehl TE, Moore BD, Fassan M, Rugge M, Romero-Gallo J, Noto J, Peek RM Jr, Stenson WF, Mills JC
J Biol Chem. 2013 May 31; 288(22)16085-97. doi: 10.1074/jbc.M112.445551.

PMID:
    23589310
    [PubMed - indexed for MEDLINE]
Related citations


Postnatal growth in the intestine.
Stenson WF
Curr Opin Gastroenterol. 2013 Mar; 29(2)107-11. doi: 10.1097/MOG.0b013e32835d9ec3.

PMID:
    23286926
    [PubMed - indexed for MEDLINE]
Related citations


CD36-dependent signaling mediates fatty acid-induced gut release of secretin and cholecystokinin.
Sundaresan S, Shahid R, Riehl TE, Chandra R, Nassir F, Stenson WF, Liddle RA, Abumrad NA
FASEB J. 2013 Mar; 27(3)1191-202. doi: 10.1096/fj.12-217703.

PMID:
    23233532
    [PubMed - indexed for MEDLINE]
Related citations


Hyaluronic acid regulates normal intestinal and colonic growth in mice.
Riehl TE, Ee X, Stenson WF
Am J Physiol Gastrointest Liver Physiol. 2012 Aug 1; 303(3)G377-88. doi: 10.1152/ajpgi.00034.2012.

PMID:
    22556141
    [PubMed - indexed for MEDLINE]
Related citations


Hyaluronic acid is radioprotective in the intestine through a TLR4 and COX-2-mediated mechanism.
Riehl TE, Foster L, Stenson WF
Am J Physiol Gastrointest Liver Physiol. 2012 Feb 1; 302(3)G309-16. doi: 10.1152/ajpgi.00248.2011.

PMID:
    22038822
    [PubMed - indexed for MEDLINE]
Related citations


Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner.
Ciorba MA, Riehl TE, Rao MS, Moon C, Ee X, Nava GM, Walker MR, Marinshaw JM, Stappenbeck TS, Stenson WF
Gut. 2012 Jun; 61(6)829-38. doi: 10.1136/gutjnl-2011-300367.

PMID:
    22027478
    [PubMed - indexed for MEDLINE]
Related citations


Serum analysis of tryptophan catabolism pathway: correlation with Crohn's disease activity.
Gupta NK, Thaker AI, Kanuri N, Riehl TE, Rowley CW, Stenson WF, Ciorba MA
Inflamm Bowel Dis. 2012 Jul; 18(7)1214-20. doi: 10.1002/ibd.21849.

PMID:
    21823214
    [PubMed - indexed for MEDLINE]
Related citations


COX-1(+/-)COX-2(-/-) genotype in mice is associated with shortened time to carotid artery occlusion through increased PAI-1.
Riehl TE, He L, Zheng L, Greco S, Tollefsen DM, Stenson WF
J Thromb Haemost. 2011 Feb; 9(2)350-60. doi: 10.1111/j.1538-7836.2010.04156.x.

PMID:
    21138526
    [PubMed - indexed for MEDLINE]
Related citations


Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis.
Ciorba MA, Bettonville EE, McDonald KG, Metz R, Prendergast GC, Newberry RD, Stenson WF
J Immunol. 2010 Apr 1; 184(7)3907-16. doi: 10.4049/jimmunol.0900291.

PMID:
    20181893
    [PubMed - indexed for MEDLINE]
Related citations


Growth factor regulation of prostaglandin-endoperoxide synthase 2 (Ptgs2) expression in colonic mesenchymal stem cells.
Walker MR, Brown SL, Riehl TE, Stenson WF, Stappenbeck TS
J Biol Chem. 2010 Feb 12; 285(7)5026-39. doi: 10.1074/jbc.M109.032672.

PMID:
    20018844
    [PubMed - indexed for MEDLINE]
Related citations


Hyaluronic acid and intestinal inflammation.
Stenson WF
Curr Opin Gastroenterol. 2010 Mar; 26(2)85-7. doi: 10.1097/MOG.0b013e328334b417.

PMID:
    19926985
    [PubMed - indexed for MEDLINE]
Related citations