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William E. Gillanders, MD

Professor, Surgery
Vice Chair for Research, Surgery
Division of General Surgery
Section of Endocrine and Oncologic Surgery

Specialty Areas

Thyroid Surgery
Parathyroid Surgery
Breast Surgery
Breast Cancer

Board Certifications

General Surgery

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Endocrine surgery, including thyroid and parathyroid surgery; minimally invasive parathyroid surgery; breast surgery, including breast cancer surgery

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Breast Health Center

4921 Parkview Place
St. Louis, MO 63110

Suite: F
Floor: 5
Office Phone: 314-362-2280
Fax: 314-454 5509

Education

Education

Master of Science: Clinical Research, Medical University of South Carolina, Charleston, South Carolina 2005
Chief Resident: Washington University School of Medicine, St. Louis, Missouri 1999
Residency: Surgery, Washington University School of Medicine, St. Louis Missouri 1998
Fellowship: Surgical Oncology Research, Washington University in St. Louis, St. Louis Missouri 1996
Medical School: Duke University School of Medicine, Durham, North Carolina 1991
Bachelor of Arts: Williams College, Williamstown, Massachusetts 1987

Publication & Research

Publication & Research

Personalized cancer vaccines: Targeting the cancer mutanome.
Zhang X, Sharma PK, Peter Goedegebuure S, Gillanders WE
Vaccine. 2016 Jul 20; pii: S0264-410X(16)30399-1. doi: 10.1016/j.vaccine.2016.05.073.

PMID:
    27449681
    [PubMed - as supplied by publisher]
Related citations


Successful Completion of the Pilot Phase of a Randomized Controlled Trial Comparing Sentinel Lymph Node Biopsy to No Further Axillary Staging in Patients with Clinical T1-T2 N0 Breast Cancer and Normal Axillary Ultrasound.
Cyr AE, Tucker N, Ademuyiwa F, Margenthaler JA, Aft RL, Eberlein TJ, Appleton CM, Zoberi I, Thomas MA, Gao F, Gillanders WE
J Am Coll Surg. 2016 Aug; 223(2)399-407. doi: 10.1016/j.jamcollsurg.2016.04.048.

PMID:
    27212005
    [PubMed - in process]
Related citations


Mammaglobin-A is a target for breast cancer vaccination.
Kim SW, Goedegebuure P, Gillanders WE
Oncoimmunology. 2016 Feb; 5(2)e1069940.

PMID:
    27057470
    [PubMed]
Related citations


Axillary Ultrasound Accurately Excludes Clinically Significant Lymph Node Disease in Patients With Early Stage Breast Cancer.
Tucker NS, Cyr AE, Ademuyiwa FO, Tabchy A, George K, Sharma PK, Jin LX, Sanati S, Aft R, Gao F, Margenthaler JA, Gillanders WE
Ann Surg. 2016 Jan 15;

PMID:
    26779976
    [PubMed - as supplied by publisher]
Related citations


Lymphovascular space invasion and lack of downstaging after neoadjuvant chemotherapy are strong predictors of adverse outcome in young women with locally advanced breast cancer.
Khwaja SS, Ivanovich J, DeWees TA, Ochoa L, Mullen DF, Thomas M, Margenthaler JA, Cyr A, Naughton M, Sanati S, Eberlein TJ, Gillanders WE, Aft RL, Zoberi JE, Zoberi I
Cancer Med. 2016 Feb; 5(2)230-8. doi: 10.1002/cam4.586.

PMID:
    26687192
    [PubMed - in process]
Related citations


Management of the Parathyroid Glands During Preventive Thyroidectomy in Patients With Multiple Endocrine Neoplasia Type 2.
Moley JF, Skinner M, Gillanders WE, Lairmore TC, Rowland KJ, Traugott AL, Jin LX, Wells SA Jr
Ann Surg. 2015 Oct; 262(4)641-6. doi: 10.1097/SLA.0000000000001464.

PMID:
    26366543
    [PubMed - indexed for MEDLINE]
Related citations


Developing a clinical development paradigm for translation of a mammaglobin-A DNA vaccine.
Li L, Goedegebuure SP, Fleming TP, Gillanders WE
Immunotherapy. 2015; 7(7)709-11. doi: 10.2217/imt.15.40.

PMID:
    26250406
    [PubMed - indexed for MEDLINE]
Related citations


Safety and preliminary evidence of biologic efficacy of a mammaglobin-a DNA vaccine in patients with stable metastatic breast cancer.
Tiriveedhi V, Tucker N, Herndon J, Li L, Sturmoski M, Ellis M, Ma C, Naughton M, Lockhart AC, Gao F, Fleming T, Goedegebuure P, Mohanakumar T, Gillanders WE
Clin Cancer Res. 2014 Dec 1; 20(23)5964-75. doi: 10.1158/1078-0432.CCR-14-0059.

PMID:
    25451106
    [PubMed - indexed for MEDLINE]
Related citations


Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens.
Gubin MM, Zhang X, Schuster H, Caron E, Ward JP, Noguchi T, Ivanova Y, Hundal J, Arthur CD, Krebber WJ, Mulder GE, Toebes M, Vesely MD, Lam SS, Korman AJ, Allison JP, Freeman GJ, Sharpe AH, Pearce EL, Schumacher TN, Aebersold R, Rammensee HG, Melief CJ, Mardis ER, Gillanders WE, Artyomov MN, Schreiber RD
Nature. 2014 Nov 27; 515(7528)577-81. doi: 10.1038/nature13988.

PMID:
    25428507
    [PubMed - indexed for MEDLINE]
Related citations


Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.
Barbie TU, Alexe G, Aref AR, Li S, Zhu Z, Zhang X, Imamura Y, Thai TC, Huang Y, Bowden M, Herndon J, Cohoon TJ, Fleming T, Tamayo P, Mesirov JP, Ogino S, Wong KK, Ellis MJ, Hahn WC, Barbie DA, Gillanders WE
J Clin Invest. 2014 Dec; 124(12)5411-23. doi: 10.1172/JCI75661.

PMID:
    25365225
    [PubMed - indexed for MEDLINE]
Related citations


Identification and translational validation of novel mammaglobin-A CD8 T cell epitopes.
Soysal SD, Muenst S, Kan-Mitchell J, Huarte E, Zhang X, Wilkinson-Ryan I, Fleming T, Tiriveedhi V, Mohanakumar T, Li L, Herndon J, Oertli D, Goedegebuure SP, Gillanders WE
Breast Cancer Res Treat. 2014 Oct; 147(3)527-37. doi: 10.1007/s10549-014-3129-x.

PMID:
    25212176
    [PubMed - indexed for MEDLINE]
Related citations


Author's response to "Letter to the editor: unvalidated antibodies and misleading results".
Muenst S, Tzankov A, Gillanders WE, Soysal SD
Breast Cancer Res Treat. 2014 Sep; 147(2)459-62. doi: 10.1007/s10549-014-3064-x.

PMID:
    25082517
    [PubMed - indexed for MEDLINE]
Related citations


Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer.
Muenst S, Schaerli AR, Gao F, Däster S, Trella E, Droeser RA, Muraro MG, Zajac P, Zanetti R, Gillanders WE, Weber WP, Soysal SD
Breast Cancer Res Treat. 2014 Jul; 146(1)15-24. doi: 10.1007/s10549-014-2988-5.

PMID:
    24842267
    [PubMed - indexed for MEDLINE]
Related citations


Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.
Zhu Z, Aref AR, Cohoon TJ, Barbie TU, Imamura Y, Yang S, Moody SE, Shen RR, Schinzel AC, Thai TC, Reibel JB, Tamayo P, Godfrey JT, Qian ZR, Page AN, Maciag K, Chan EM, Silkworth W, Labowsky MT, Rozhansky L, Mesirov JP, Gillanders WE, Ogino S, Hacohen N, Gaudet S, Eck MJ, Engelman JA, Corcoran RB, Wong KK, Hahn WC, Barbie DA
Cancer Discov. 2014 Apr; 4(4)452-65. doi: 10.1158/2159-8290.CD-13-0646.

PMID:
    24444711
    [PubMed - indexed for MEDLINE]
Related citations


A prospective longitudinal clinical trial evaluating quality of life after breast-conserving surgery and high-dose-rate interstitial brachytherapy for early-stage breast cancer.
Garsa AA, Ferraro DJ, DeWees TA, Deshields TL, Margenthaler JA, Cyr AE, Naughton M, Aft R, Gillanders WE, Eberlein T, Matesa MA, Ochoa LL, Zoberi I
Int J Radiat Oncol Biol Phys. 2013 Dec 1; 87(5)1043-50. doi: 10.1016/j.ijrobp.2013.09.009.

PMID:
    24161428
    [PubMed - indexed for MEDLINE]
Related citations


The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer.
Muenst S, Soysal SD, Gao F, Obermann EC, Oertli D, Gillanders WE
Breast Cancer Res Treat. 2013 Jun; 139(3)667-76. doi: 10.1007/s10549-013-2581-3.

PMID:
    23756627
    [PubMed - indexed for MEDLINE]
Related citations


Src homology phosphotyrosyl phosphatase-2 expression is an independent negative prognostic factor in human breast cancer.
Muenst S, Obermann EC, Gao F, Oertli D, Viehl CT, Weber WP, Fleming T, Gillanders WE, Soysal SD
Histopathology. 2013 Jul; 63(1)74-82. doi: 10.1111/his.12140.

PMID:
    23672411
    [PubMed - indexed for MEDLINE]
Related citations


EpCAM expression varies significantly and is differentially associated with prognosis in the luminal B HER2(+), basal-like, and HER2 intrinsic subtypes of breast cancer.
Soysal SD, Muenst S, Barbie T, Fleming T, Gao F, Spizzo G, Oertli D, Viehl CT, Obermann EC, Gillanders WE
Br J Cancer. 2013 Apr 16; 108(7)1480-7. doi: 10.1038/bjc.2013.80.

PMID:
    23519058
    [PubMed - indexed for MEDLINE]
Related citations


EpCAM modulates NF-κB signaling and interleukin-8 expression in breast cancer.
Sankpal NV, Fleming TP, Gillanders WE
Mol Cancer Res. 2013 Apr; 11(4)418-26. doi: 10.1158/1541-7786.MCR-12-0518.

PMID:
    23378578
    [PubMed - indexed for MEDLINE]
Related citations


PTP1B expression is an independent positive prognostic factor in human breast cancer.
Soysal S, Obermann EC, Gao F, Oertli D, Gillanders WE, Viehl CT, Muenst S
Breast Cancer Res Treat. 2013 Jan; 137(2)637-44. doi: 10.1007/s10549-012-2373-1.

PMID:
    23242616
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Cancer vaccine development, breast cancer biology