Patient Portal

William C. Chapman, MD, FACS

Professor, Surgery
Eugene M. Bricker Chair of Surgery
Chief, Division of General Surgery
Chief, Abdominal Transplantation Section

Specialty Areas

Liver Surgery
Transplantation Surgery
Hepatobiliary Surgery
Liver Diseases
Pediatric Liver Transplantation
Liver Transplantation

Board Certifications

Critical Care
General Surgery

Hospital Affiliations

St. Louis Children's Hospital
Barnes-Jewish Hospital
VA Medical Center - St. Louis

Areas of Clinical Interest

Surgical treatment of complex hepatobiliary conditions, image-guided liver surgery, gallstone pathogenesis and prevention, hepatic transplant immunosuppression, hepatic surgery, bile duct surgery, liver surgery, bile duct surgery, surgery for portal hypertension, radiofrequency ablation (RFA) of liver tumors, cryoablation, hepatic artery infusion (HAI) pumps, liver transplant in adults, liver transplant in children, living donor, living adult related donor, adult to adult liver doner, live doner transplant

  • Location(s)
  • Education
  • Publication & Research
  • Videos

Location(s)

Location(s)

Center for Advanced Medicine
Gastrointestinal Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 8
Office Phone: (314) 362-2538
Additional Phone: 314-362-7792.
Fax: 314-361-4197

Education

Education

Fellowship: Hepatobiliary Surgery and Liver Transplantation, Kings College Hospital, London, England 1992
Chief Residency: General Surgery, Vanderbilt University Hospital, Nashville, Tennessee 1991
Fellowship: Hepatobiliary Research, Vanderbilt University Medical Center, Nashville, Tennesee 1989
Residency: General Surgery, Vanderbilt University Hospital, Nashville, Tennessee 1987
Medical Degree: Medical University of South Carolina, Charleston, South Carolina 1984
B.A.: Chemistry, University of North Carolina, Chapel Hill, North Carolina 1980

Publication & Research

Publication & Research

Utilization Trends, Outcomes, and Cost in Minimally Invasive Lobectomy.
Subramanian MP, Liu J, Chapman WC Jr, Olsen MA, Yan Y, Liu Y, Semenkovich TR, Meyers BF, Puri V, Kozower BD
Ann Thorac Surg. 2019 Aug 7; pii: S0003-4975(19)31097-5. doi: 10.1016/j.athoracsur.2019.06.049.

PMID:
    31400324
    [PubMed - as supplied by publisher]
Related citations


A 22-year experience with pancreatic resection for metastatic renal cell carcinoma.
Anderson B, Williams GA, Sanford DE, Lu J, Dageforde LA, Hammill CW, Fields RC, Hawkins WG, Strasberg SM, Doyle MB, Chapman WC, Khan AS
HPB (Oxford). 2019 Jul 23; pii: S1365-182X(19)30569-6. doi: 10.1016/j.hpb.2019.05.019.

PMID:
    31345661
    [PubMed - as supplied by publisher]
Related citations


Pathologic Response to Pretransplant Locoregional Therapy is Predictive of Patient Outcome After Liver Transplantation for Hepatocellular Carcinoma: Analysis From the US Multicenter HCC Transplant Consortium.
DiNorcia J, Florman SS, Haydel B, Tabrizian P, Ruiz RM, Klintmalm GB, Senguttuvan S, Lee DD, Taner CB, Verna EC, Halazun KJ, Hoteit M, Levine MH, Chapman WC, Vachharajani N, Aucejo F, Nguyen MH, Melcher ML, Tevar AD, Humar A, Mobley C, Ghobrial M, Nydam TL, Amundsen B, Markmann JF, Berumen J, Hemming AW, Langnas AN, Carney CA, Sudan DL, Hong JC, Kim J, Zimmerman MA, Rana A, Kueht ML, Jones CM, Fishbein TM, Markovic D, Busuttil RW, Agopian VG
Ann Surg. 2019 Mar 5; doi: 10.1097/SLA.0000000000003253.

PMID:
    30870180
    [PubMed - as supplied by publisher]
Related citations


The Angular Spectrum of the Scattering Coefficient Map Reveals Subsurface Colorectal Cancer.
Zeng Y, Rao B, Chapman WC Jr, Nandy S, Rais R, González I, Chatterjee D, Mutch M, Zhu Q
Sci Rep. 2019 Feb 28; 9(1)2998. doi: 10.1038/s41598-019-39146-w.

PMID:
    30816153
    [PubMed - in process]
Related citations


Unintended consequences of changes to lung allocation policy.
Puri V, Hachem RR, Frye CC, Harrison MS, Semenkovich TR, Lynch JP, Ridolfi G, Rowe C, Meyers BF, Patterson GA, Kozower BD, Pasque MK, Nava RG, Marklin GF, Brockmeier D, Sweet SC, Chapman WC, Kreisel D
Am J Transplant. 2019 Aug; 19(8)2164-2167. doi: 10.1111/ajt.15307.

PMID:
    30758137
    [PubMed - in process]
Related citations


Management of Bouveret's syndrome.
Abdallah MA, Atiq M, Kushnir V, Das KK, Doyle MB, Chapman WC, Khan AS
J Dig Dis. 2019 Apr; 20(4)215-219. doi: 10.1111/1751-2980.12713.

PMID:
    30756478
    [PubMed - in process]
Related citations


Response to the Comment on "Prediction of Hepatocellular Carcinoma Recurrence Beyond Milan Criteria After Resection: Validation of a Clinical Risk Score in Aninternational Cohort".
Zheng J, Chapman WC, Turcotte S, Koerkamp BG, Lee SY, Jarnagin WR
Ann Surg. 2019 Mar; 269(3)e34-e35. doi: 10.1097/SLA.0000000000002871.

PMID:
    30724808
    [PubMed - in process]
Related citations


Racial/Ethnic Disparities in Access and Outcomes of Simultaneous Liver-Kidney Transplant Among Liver Transplant Candidates With Renal Dysfunction in the United States.
Chang SH, Wang M, Liu X, Alhamad T, Lentine KL, Schnitzler MA, Colditz GA, Park Y, Chapman WC
Transplantation. 2019 Aug; 103(8)1663-1674. doi: 10.1097/TP.0000000000002574.

PMID:
    30720678
    [PubMed - in process]
Related citations


Long-Term Endocrine and Exocrine Insufficiency After Pancreatectomy.
Kusakabe J, Anderson B, Liu J, Williams GA, Chapman WC, Doyle MMB, Khan AS, Sanford DE, Hammill CW, Strasberg SM, Hawkins WG, Fields RC
J Gastrointest Surg. 2019 Aug; 23(8)1604-1613. doi: 10.1007/s11605-018-04084-x.

PMID:
    30671791
    [PubMed - in process]
Related citations


First, Do No Harm: Rethinking Routine Diversion in Sphincter-Preserving Rectal Cancer Resection.
Chapman WC Jr, Subramanian M, Jayarajan S, Makhdoom B, Mutch MG, Hunt S, Silviera ML, Glasgow SC, Olsen MA, Wise PE
J Am Coll Surg. 2019 Apr; 228(4)547-556.e8. doi: 10.1016/j.jamcollsurg.2018.12.012.

PMID:
    30639302
    [PubMed - in process]
Related citations


Hepatocellular carcinoma: Where are we in 2018?
Chapman WC, Korenblat KM, Fowler KJ, Saad N, Khan AS, Subramanian V, Doyle MBM, Dageforde LA, Tan B, Grierson P, Lin Y, Xu M, Brunt EM
Curr Probl Surg. 2018 Nov; 55(11)450-503. doi: 10.1067/j.cpsurg.2018.10.002.

PMID:
    30526875
    [PubMed - indexed for MEDLINE]
Related citations


Accounting for proximal variants improves neoantigen prediction.
Hundal J, Kiwala S, Feng YY, Liu CJ, Govindan R, Chapman WC, Uppaluri R, Swamidass SJ, Griffith OL, Mardis ER, Griffith M
Nat Genet. 2019 Jan; 51(1)175-179. doi: 10.1038/s41588-018-0283-9.

PMID:
    30510237
    [PubMed - indexed for MEDLINE]
Related citations


Systemic Therapy for Combined Hepatocellular-Cholangiocarcinoma: A Single-Institution Experience.
Trikalinos NA, Zhou A, Doyle MBM, Fowler KJ, Morton A, Vachharajani N, Amin M, Keller JW, Chapman WC, Brunt EM, Tan BR
J Natl Compr Canc Netw. 2018 Oct; 16(10)1193-1199. doi: 10.6004/jnccn.2018.7053.

PMID:
    30323089
    [PubMed - in process]
Related citations


Thoracic Epidural Analgesia: Does It Enhance Recovery?
Rosen DR, Wolfe RC, Damle A, Atallah C, Chapman WC Jr, Vetter JM, Mutch MG, Hunt SR, Glasgow SC, Wise PE, Smith RK, Silviera ML
Dis Colon Rectum. 2018 Dec; 61(12)1403-1409. doi: 10.1097/DCR.0000000000001226.

PMID:
    30308525
    [PubMed - indexed for MEDLINE]
Related citations


Antithrombin Perfluorocarbon Nanoparticles Improve Renal Allograft Function in a Murine Deceased Criteria Donor Model.
Vemuri C, Upadhya GA, Arif B, Jia J, Lin Y, Gaut JP, Fazal J, Pan H, Wickline SA, Chapman WC
Transplant Direct. 2018 Sep; 4(9)e384. doi: 10.1097/TXD.0000000000000817.

PMID:
    30234153
    [PubMed]
Related citations


Enhanced immunosuppression improves early allograft function in a porcine kidney transplant model of donation after circulatory death.
Xu M, Garcia-Aroz S, Banan B, Wang X, Rabe BJ, Zhou F, Nayak DK, Zhang Z, Jia J, Upadhya GA, Manning PT, Gaut JP, Lin Y, Chapman WC
Am J Transplant. 2019 Mar; 19(3)713-723. doi: 10.1111/ajt.15098.

PMID:
    30152136
    [PubMed - in process]
Related citations


"Response to Letter to the Editor: Impact of Recurrence Surveillance on Recurrence Patterns After Resection of Hepatocellular Carcinoma".
Zheng J, Chapman WC, Turcotte S, Koerkamp BG, Lee SY, Jarnagin WR
Ann Surg. 2018 Jun 28; doi: 10.1097/SLA.0000000000002871.

PMID:
    29958228
    [PubMed - as supplied by publisher]
Related citations


The importance of early recognition in management of ERCP-related perforations.
Bill JG, Smith Z, Brancheck J, Elsner J, Hobbs P, Lang GD, Early DS, Das K, Hollander T, Doyle MBM, Fields RC, Hawkins WG, Strasberg SM, Hammill C, Chapman WC, Edmundowicz S, Mullady DK, Kushnir VM
Surg Endosc. 2018 Dec; 32(12)4841-4849. doi: 10.1007/s00464-018-6235-8.

PMID:
    29770887
    [PubMed - in process]
Related citations


Benchmarking rectal cancer care: institutional compliance with a longitudinal checklist.
Chapman WC Jr, Choi P, Hawkins AT, Hunt SR, Silviera ML, Wise PE, Mutch MG, Glasgow SC
J Surg Res. 2018 May; 225142-147. doi: 10.1016/j.jss.2018.01.006.

PMID:
    29605024
    [PubMed - indexed for MEDLINE]
Related citations


Utility of Endoscopic Ultrasound in Evaluating Local Recurrence After Surgery for Pancreatic Cancer.
Lang GD, Mullady DK, Early DS, Hollander T, Edmundowicz SA, Murad FM, Strasberg SM, Fields RC, Hawkins WG, Doyle MB, Chapman WC, Wang-Gillam A, Kushnir VM
Clin Gastroenterol Hepatol. 2018 Nov; 16(11)1834-1835. doi: 10.1016/j.cgh.2018.02.031.

PMID:
    29505906
    [PubMed - in process]
Related citations

Videos

Videos

Areas of Research Interest

Liver-lung interactions following liver injury, Image-guided liver surgery, Transcriptional regulation of hepatocellular carcinoma, Surgical Treatment of complex hepatobiliary problems, Hepatic transplant immunosuppression, Gallstone pathogenesis and prevention