Patient Portal

William C. Chapman, MD, FACS

Professor, Surgery
Eugene M. Bricker Chair of Surgery
Chief, Division of General Surgery
Chief, Abdominal Transplantation Section

Specialty Areas

Liver Surgery
Transplantation Surgery
Hepatobiliary Surgery
Liver Diseases
Pediatric Liver Transplantation
Liver Transplantation

Board Certifications

Critical Care
General Surgery

Hospital Affiliations

St. Louis Children's Hospital
Barnes-Jewish Hospital
VA Medical Center - St. Louis

Areas of Clinical Interest

Surgical treatment of complex hepatobiliary conditions, image-guided liver surgery, gallstone pathogenesis and prevention, hepatic transplant immunosuppression, hepatic surgery, bile duct surgery, liver surgery, bile duct surgery, surgery for portal hypertension, radiofrequency ablation (RFA) of liver tumors, cryoablation, hepatic artery infusion (HAI) pumps, liver transplant in adults, liver transplant in children, living donor, living adult related donor, adult to adult liver doner, live doner transplant

  • Location(s)
  • Education
  • Publication & Research
  • Videos

Location(s)

Location(s)

Center for Advanced Medicine
Gastrointestinal Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 8
Office Phone: (314) 362-2538
Additional Phone: 314-362-7792.
Fax: 314-361-4197

Education

Education

Fellowship: Hepatobiliary Surgery and Liver Transplantation, Kings College Hospital, London, England 1992
Chief Residency: General Surgery, Vanderbilt University Hospital, Nashville, Tennessee 1991
Fellowship: Hepatobiliary Research, Vanderbilt University Medical Center, Nashville, Tennesee 1989
Residency: General Surgery, Vanderbilt University Hospital, Nashville, Tennessee 1987
Medical Degree: Medical University of South Carolina, Charleston, South Carolina 1984
B.A.: Chemistry, University of North Carolina, Chapel Hill, North Carolina 1980

Publication & Research

Publication & Research

Feasibility and safety of non-operative management of portal vein aneurysms: a thirty-five year experience.
Ahmed O, Ohman JW, Vachharajani N, Yano M, Sanford DE, Hammill C, Fields RC, Hawkins WG, Strasberg SM, Doyle MB, Chapman WC, Khan AS
HPB (Oxford). 2020 Jun 16; pii: S1365-182X(20)31021-2. doi: 10.1016/j.hpb.2020.05.006.

PMID:
    32561177
    [PubMed - as supplied by publisher]
Related citations


Surgical Therapy for Pediatric Hepatoblastoma in the USA over the Last Decade: Analysis of the National Cancer Database.
Kulkarni S, Brauer DG, Turmelle Y, Stoll J, Nadler M, Chapman WC, Doyle MB, Khan AS
J Gastrointest Cancer. 2020 May 27; doi: 10.1007/s12029-020-00421-z.

PMID:
    32458263
    [PubMed - as supplied by publisher]
Related citations


Incisional hernia after liver transplantation: Risk factors, management strategies and long-term outcomes of a cohort study.
Cos H, Ahmed O, Garcia-Aroz S, Vachharajani N, Shenoy S, Wellen JR, Doyle MM, Chapman WC, Khan AS
Int J Surg. 2020 Jun; 78149-153. doi: 10.1016/j.ijsu.2020.04.048.

PMID:
    32335240
    [PubMed - in process]
Related citations


Perioperative Complications After Proctectomy for Rectal Cancer: Does Neoadjuvant Regimen Matter?
Bauer PS, Chapman WC Jr, Atallah C, Makhdoom BA, Damle A, Smith RK, Wise PE, Glasgow SC, Silviera ML, Hunt SR, Mutch MG
Ann Surg. 2020 Mar 20; doi: 10.1097/SLA.0000000000003885.

PMID:
    32209914
    [PubMed - as supplied by publisher]
Related citations


Real-time colorectal cancer diagnosis using PR-OCT with deep learning.
Zeng Y, Xu S, Chapman WC Jr, Li S, Alipour Z, Abdelal H, Chatterjee D, Mutch M, Zhu Q
Theranostics. 2020; 10(6)2587-2596. doi: 10.7150/thno.40099.

PMID:
    32194821
    [PubMed - in process]
Related citations


Adaptive Boosting (AdaBoost)-based multiwavelength spatial frequency domain imaging and characterization for ex vivo human colorectal tissue assessment.
Li S, Zeng Y, Chapman WC Jr, Erfanzadeh M, Nandy S, Mutch M, Zhu Q
J Biophotonics. 2020 Jun; 13(6)e201960241. doi: 10.1002/jbio.201960241.

PMID:
    32125775
    [PubMed - in process]
Related citations


Liver Transplantation Outcomes in a U.S. Multicenter Cohort of 789 Patients with Hepatocellular Carcinoma Presenting Beyond Milan Criteria.
Kardashian A, Florman SS, Haydel B, Ruiz RM, Klintmalm GB, Lee DD, Taner CB, Aucejo F, Tevar AD, Humar A, Verna EC, Halazun KJ, Chapman WC, Vachharajani N, Hoteit M, Levine MH, Nguyen MH, Melcher ML, Langnas AN, Carney CA, Mobley C, Ghobrial M, Amundsen B, Markmann JF, Sudan DL, Jones CM, Berumen J, Hemming AW, Hong JC, Kim J, Zimmerman MA, Nydam TL, Rana A, Kueht ML, Fishbein TM, Markovic D, Busuttil RW, Agopian VG
Hepatology. 2020 Mar 2; doi: 10.1002/hep.31210.

PMID:
    32124453
    [PubMed - as supplied by publisher]
Related citations


Punctuality Matters: Starting on Time Remains Key Among Many Factors: In Reply to Tsai and Dexter.
Chapman WC Jr, Luo X, Wellen J
J Am Coll Surg. 2020 May; 230(5)839. doi: 10.1016/j.jamcollsurg.2020.01.007.

PMID:
    32093968
    [PubMed - in process]
Related citations


Liver transplantation for hepatitis C patients in the era of direct-acting antiviral treatment: A retrospective cohort study.
Khan AS, Adams N, Vachharajani N, Dageforde L, Wellen J, Shenoy S, Crippin JS, Doyle MB, Chapman WC
Int J Surg. 2020 Mar; 7584-90. doi: 10.1016/j.ijsu.2020.01.145.

PMID:
    32014598
    [PubMed - in process]
Related citations


Clinicopathologic determinants of pathologic treatment response in neoadjuvant treated rectal adenocarcinoma.
González I, Bauer PS, Chapman WC Jr, Alipour Z, Rais R, Liu J, Chatterjee D
Ann Diagn Pathol. 2020 Apr; 45151452. doi: 10.1016/j.anndiagpath.2019.151452.

PMID:
    31945621
    [PubMed - in process]
Related citations


Composite Length of Stay, An Outcome Measure of Postoperative and Readmission Length of Stays in Pancreatoduodenectomy.
Williams GA, Liu J, Chapman WC, Hawkins WG, Fields RC, Sanford DE, Doyle MB, Hammill CW, Khan AS, Strasberg SM
J Gastrointest Surg. 2019 Dec 16; doi: 10.1007/s11605-019-04475-8.

PMID:
    31845140
    [PubMed - as supplied by publisher]
Related citations


Time Is Money: Can Punctuality Decrease Operating Room Cost?
Chapman WC Jr, Luo X, Doyle M, Khan A, Chapman WC, Kangrga I, Martin J Jr, Wellen J
J Am Coll Surg. 2020 Feb; 230(2)182-189.e4. doi: 10.1016/j.jamcollsurg.2019.10.017.

PMID:
    31843690
    [PubMed - in process]
Related citations


Assessment of Hepatic Arterial Infusion of Floxuridine in Combination With Systemic Gemcitabine and Oxaliplatin in Patients With Unresectable Intrahepatic Cholangiocarcinoma: A Phase 2 Clinical Trial.
Cercek A, Boerner T, Tan BR, Chou JF, Gönen M, Boucher TM, Hauser HF, Do RKG, Lowery MA, Harding JJ, Varghese AM, Reidy-Lagunes D, Saltz L, Schultz N, Kingham TP, D'Angelica MI, DeMatteo RP, Drebin JA, Allen PJ, Balachandran VP, Lim KH, Sanchez-Vega F, Vachharajani N, Majella Doyle MB, Fields RC, Hawkins WG, Strasberg SM, Chapman WC, Diaz LA Jr, Kemeny NE, Jarnagin WR
JAMA Oncol. 2019 Oct 31; doi: 10.1001/jamaoncol.2019.3718.

PMID:
    31670750
    [PubMed - as supplied by publisher]
Related citations


Utilization Trends, Outcomes, and Cost in Minimally Invasive Lobectomy.
Subramanian MP, Liu J, Chapman WC Jr, Olsen MA, Yan Y, Liu Y, Semenkovich TR, Meyers BF, Puri V, Kozower BD
Ann Thorac Surg. 2019 Dec; 108(6)1648-1655. doi: 10.1016/j.athoracsur.2019.06.049.

PMID:
    31400324
    [PubMed - indexed for MEDLINE]
Related citations


A 22-year experience with pancreatic resection for metastatic renal cell carcinoma.
Anderson B, Williams GA, Sanford DE, Liu J, Dageforde LA, Hammill CW, Fields RC, Hawkins WG, Strasberg SM, Doyle MB, Chapman WC, Khan AS
HPB (Oxford). 2020 Feb; 22(2)312-317. doi: 10.1016/j.hpb.2019.05.019.

PMID:
    31345661
    [PubMed - in process]
Related citations


Pathologic Response to Pretransplant Locoregional Therapy is Predictive of Patient Outcome After Liver Transplantation for Hepatocellular Carcinoma: Analysis From the US Multicenter HCC Transplant Consortium.
DiNorcia J, Florman SS, Haydel B, Tabrizian P, Ruiz RM, Klintmalm GB, Senguttuvan S, Lee DD, Taner CB, Verna EC, Halazun KJ, Hoteit M, Levine MH, Chapman WC, Vachharajani N, Aucejo F, Nguyen MH, Melcher ML, Tevar AD, Humar A, Mobley C, Ghobrial M, Nydam TL, Amundsen B, Markmann JF, Berumen J, Hemming AW, Langnas AN, Carney CA, Sudan DL, Hong JC, Kim J, Zimmerman MA, Rana A, Kueht ML, Jones CM, Fishbein TM, Markovic D, Busuttil RW, Agopian VG
Ann Surg. 2020 Apr; 271(4)616-624. doi: 10.1097/SLA.0000000000003253.

PMID:
    30870180
    [PubMed - indexed for MEDLINE]
Related citations


The Angular Spectrum of the Scattering Coefficient Map Reveals Subsurface Colorectal Cancer.
Zeng Y, Rao B, Chapman WC Jr, Nandy S, Rais R, González I, Chatterjee D, Mutch M, Zhu Q
Sci Rep. 2019 Feb 28; 9(1)2998. doi: 10.1038/s41598-019-39146-w.

PMID:
    30816153
    [PubMed - in process]
Related citations


Unintended consequences of changes to lung allocation policy.
Puri V, Hachem RR, Frye CC, Harrison MS, Semenkovich TR, Lynch JP, Ridolfi G, Rowe C, Meyers BF, Patterson GA, Kozower BD, Pasque MK, Nava RG, Marklin GF, Brockmeier D, Sweet SC, Chapman WC, Kreisel D
Am J Transplant. 2019 Aug; 19(8)2164-2167. doi: 10.1111/ajt.15307.

PMID:
    30758137
    [PubMed - in process]
Related citations


Management of Bouveret's syndrome.
Abdallah MA, Atiq M, Kushnir V, Das KK, Doyle MB, Chapman WC, Khan AS
J Dig Dis. 2019 Apr; 20(4)215-219. doi: 10.1111/1751-2980.12713.

PMID:
    30756478
    [PubMed - indexed for MEDLINE]
Related citations


Response to the Comment on "Prediction of Hepatocellular Carcinoma Recurrence Beyond Milan Criteria After Resection: Validation of a Clinical Risk Score in Aninternational Cohort".
Zheng J, Chapman WC, Turcotte S, Koerkamp BG, Lee SY, Jarnagin WR
Ann Surg. 2019 Mar; 269(3)e34-e35. doi: 10.1097/SLA.0000000000002871.

PMID:
    30724808
    [PubMed - indexed for MEDLINE]
Related citations

Videos

Videos

Areas of Research Interest

Liver-lung interactions following liver injury, Image-guided liver surgery, Transcriptional regulation of hepatocellular carcinoma, Surgical Treatment of complex hepatobiliary problems, Hepatic transplant immunosuppression, Gallstone pathogenesis and prevention