Patient Portal

Toni Pearson, MD

Associate Professor, Neurology
Medical Director, Cerebral Palsy Center

Specialty Areas

Pediatric Movement Disorders
Pediatric Neurology
Cerebral Palsy

Board Certifications

Pediatric Neurology

Areas of Clinical Interest

pediatric cerebral palsy; pediatric neurology, pediatric movement disorders; chorea, ataxia, parkinsonism, tremor, myoclonus, stereotypies

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: C
Floor: 2
Office Phone: 314-454-6120
Fax: 314-454-2523



Fellowship, Movement Disorders: Columbia University, New York, NY 2010
Residency, Child Neurology: Columbia University, New York, NY 2006
Residency, Pediatrics: Children's Hospital at Westmead, Sydney, Australia; Montreal Children's Hospital, Montreal, QC 2003
MBBS: University of Adelaide, South Australia 1998

Publication & Research

Publication & Research

1. Gain-of-Function Mutations in RARB Cause Intellectual Disability with Progressive Motor Impairment. 
Srour M, Caron V, Pearson T, Nielsen SB, Lévesque S, Delrue MA, Becker TA, Hamdan FF, Kibar Z, Sattler SG, Schneider MC, Bitoun P, Chassaing N, Rosenfeld JA, Xia F, Desai S, Roeder E, Kimonis V, Schneider A, Littlejohn RO, Douzgou S, Tremblay A, Michaud JL. Human mutation. 2016; 37(8):786-93. PubMed [journal] PMID: 27120018

2.  More Than Ataxia: Hyperkinetic Movement Disorders in Childhood Autosomal Recessive Ataxia Syndromes.
Pearson TS.(New York, N.Y.). Tremor and other hyperkinetic movements (New York, N.Y.).2016; 6:368. PubMed [journal] PMID: 27536460, PMCID: PMC4950223

3.  Ataxia with Vitamin E Deficiency May Present with Cervical Dystonia. 
Becker AE, Vargas W, Pearson TS. Tremor and other hyperkinetic movements (New York, N.Y.); 2016; 6:374. PubMed [journal] PMID: 27274910, PMCID: PMC4884265

4. Long-term clinical course of Glut1 deficiency syndrome.
Alter AS, Engelstad K, Hinton VJ, Montes J, Pearson TS, Akman CI, De Vivo DC. Journal of child neurology. 2015; 30(2):160-9. PubMed [journal] PMID: 24789115

5.  Reduction in upper-extremity tone after lumbar selective dorsal rhizotomy in children with spastic cerebral palsy.
Gigante P, McDowell MM, Bruce SS, Chirelstein G, Chiriboga CA, Dutkowsky J, Fontana E, Hyman J, Kim H, Morgan D, Pearson TS, Roye BD, Roye DP Jr, Ryan P, Vitale M, Anderson RC. Journal of neurosurgery. Pediatrics. 2013; 12(6):588-94. PubMed [journal] PMID: 24116982

6. Delayed onset of progressive chorea after acute basal ganglia injury. 
Virmani T, Greene PE, Pearson TS. Movement disorders : official journal of the Movement Disorder Society. 2013; 28(5):585-7. PubMed [journal] PMID: 23677897

7. Phenotypic spectrum of glucose transporter type 1 deficiency syndrome (Glut1 DS).
Pearson TS, Akman C, Hinton VJ, Engelstad K, De Vivo DC.  Current neurology and neuroscience reports. 2013; 13(4):342. PubMed [journal] PMID: 23443458

8. Definition and classification of hyperkinetic movements in childhood.
Sanger TD, Chen D, Fehlings DL, Hallett M, Lang AE, Mink JW, Singer HS, Alter K, Ben-Pazi H, Butler EE, Chen R, Collins A, Dayanidhi S, Forssberg H, Fowler E, Gilbert DL, Gorman SL, Gormley ME Jr, Jinnah HA, Kornblau B, Krosschell KJ, Lehman RK, MacKinnon C, Malanga CJ, Mesterman R, Michaels MB, Pearson TS, Rose J, Russman BS, Sternad D, Swoboda KJ, Valero-Cuevas F.  Movement disorders : official journal of the Movement Disorder Society. 2010; 25(11):1538-49. NIHMSID: NIHMS229838 PubMed [journal] PMID: 20589866, PMCID: PMC2929378

9.Learning not to generalize: modular adaptation of visuomotor gain.
 Pearson TS, Krakauer JW, Mazzoni P.  Journal of neurophysiology. 2010; 103(6):2938-52. PubMed [journal] PMID: 20357068, PMCID: PMC2888232

10. An intronic mutation in DKC1 in an infant with Høyeraal-Hreidarsson syndrome.
Pearson T, Curtis F, Al-Eyadhy A, Al-Tamemi S, Mazer B, Dror Y, Abish S, Bale S, Compton J, Ray R, Scott P, Der Kaloustian VM.  American journal of medical genetics. 
Part A. 2008; 146A(16):2159-61. PubMed [journal] PMID: 18627054

Areas of Research Interest

Pediatric neurotransmitter disorders, dopa-responsive dystonia; aromatic amino acid decarboxylase (AADC) deficiency, childhood dystonia