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Todd P. Margolis, MD, PhD

Alan A. and Edith L. Wolff Distinguished Professor and Chairman,
Ophthalmology and Visual Sciences

Specialty Areas

Infectious and Inflammatory Eye Disease
Corneal Disease
Uveitis
Ophthalmology

Board Certifications

Ophthalmology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

External disease, uveitis, herpes viruses, latency, herpes simplex virus, varicella zoster virus, cytomegalovirus, AIDS, molecular diagnostics, cornea, telemedicine

  • Maps & Directions
  • Education
  • Publication & Research
  • In the News

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Eye Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 12
Office Phone: (314) 362-3937
Fax: (314) 362-3725

Education

Education

Fellowship: Corneal/External Diseases, University of California, Los Angeles 1991
Fellowship: Corneal/External Disease, University of California, San Francisco 1989
Residency: Ophthalmology, University of California, San Francisco 1988
Medical Degree: University of California, San Francisco 1984
Bachelor of Science: Stanford University, Stanford, California 1977
PhD: University of California, San Francisco 1983

Publication & Research

Publication & Research

Risk factors for CMV retinitis among individuals with HIV and low CD4 count in northern Thailand: importance of access to healthcare.
Leenasirimakul P, Liu Y, Jirawison C, Khienprasit N, Kamphaengkham S, Ausayakhun S, Chen J, Yen M, Heiden D, Holland GN, Margolis TP, Keenan JD
Br J Ophthalmol. 2016 Aug; 100(8)1017-21. doi: 10.1136/bjophthalmol-2016-308556.

PMID:
    27297217
    [PubMed - in process]
Related citations


Dissociations of the Fluocinolone Acetonide Implant: The Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study.
Holbrook JT, Sugar EA, Burke AE, Vitale AT, Thorne JE, Davis JL, Jabs DA, Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group
Am J Ophthalmol. 2016 Apr; 16429-36. doi: 10.1016/j.ajo.2015.12.028.

PMID:
    26748056
    [PubMed - in process]
Related citations


Conjunctival Sensation in Scleritis.
Somkijrungroj T, Pimolrat W, Gonzales JA, Keenan JD, Margolis TP
Ocul Immunol Inflamm. 2016; 24(1)24-8. doi: 10.3109/09273948.2015.1057598.

PMID:
    26647348
    [PubMed - in process]
Related citations


Ebola and the Ophthalmologist.
Van Gelder RN, Margolis TP
Ophthalmology. 2015 Nov; 122(11)2152-4. doi: 10.1016/j.ophtha.2015.08.027.

PMID:
    26498076
    [PubMed - indexed for MEDLINE]
Related citations


Factors Predicting Visual Acuity Outcome in Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial.
Kempen JH, Van Natta ML, Altaweel MM, Dunn JP, Jabs DA, Lightman SL, Thorne JE, Holbrook JT, Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group
Am J Ophthalmol. 2015 Dec; 160(6)1133-1141.e9. doi: 10.1016/j.ajo.2015.09.017.

PMID:
    26386159
    [PubMed - indexed for MEDLINE]
Related citations


Incomplete response to artificial tears is associated with features of neuropathic ocular pain.
Galor A, Batawi H, Felix ER, Margolis TP, Sarantopoulos KD, Martin ER, Levitt RC
Br J Ophthalmol. 2016 Jun; 100(6)745-9. doi: 10.1136/bjophthalmol-2015-307094.

PMID:
    26377416
    [PubMed - in process]
Related citations


Outcome of Treatment of Uveitic Macular Edema: The Multicenter Uveitis Steroid Treatment Trial 2-Year Results.
Tomkins-Netzer O, Lightman S, Drye L, Kempen J, Holland GN, Rao NA, Stawell RJ, Vitale A, Jabs DA, Multicenter Uveitis Steroid Treatment Trial Research Group
Ophthalmology. 2015 Nov; 122(11)2351-9. doi: 10.1016/j.ophtha.2015.07.036.

PMID:
    26359188
    [PubMed - indexed for MEDLINE]
Related citations


Topical Valganciclovir for the Treatment of Hypertensive Anterior Uveitis.
Delwig A, Keenan JD, Margolis TP
Cornea. 2015 Nov; 34(11)1513-5. doi: 10.1097/ICO.0000000000000579.

PMID:
    26356754
    [PubMed - indexed for MEDLINE]
Related citations


Quality of Life and Risks Associated with Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, or Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatment Trial and Follow-up Study.
Multicenter Uveitis Steroid Treatment (MUST) Trial Follow-up Study Research Group
Ophthalmology. 2015 Oct; 122(10)1976-86. doi: 10.1016/j.ophtha.2015.06.043.

PMID:
    26298718
    [PubMed - indexed for MEDLINE]
Related citations


Benefits of Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, and Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study.
Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group, Kempen JH, Altaweel MM, Drye LT, Holbrook JT, Jabs DA, Sugar EA, Thorne JE
Ophthalmology. 2015 Oct; 122(10)1967-75. doi: 10.1016/j.ophtha.2015.06.042.

PMID:
    26298715
    [PubMed - indexed for MEDLINE]
Related citations


Remembering David C. Beebe, PhD, 1944-2015.
Margolis TP
Invest Ophthalmol Vis Sci. 2015 Jul; 56(8)4975. doi: 10.1167/iovs.15-17592.

PMID:
    26230761
    [PubMed - indexed for MEDLINE]
Related citations


Dry eye symptoms align more closely to non-ocular conditions than to tear film parameters.
Galor A, Felix ER, Feuer W, Shalabi N, Martin ER, Margolis TP, Sarantopoulos CD, Levitt RC
Br J Ophthalmol. 2015 Aug; 99(8)1126-9. doi: 10.1136/bjophthalmol-2014-306481.

PMID:
    25710726
    [PubMed - indexed for MEDLINE]
Related citations


Characterization of herpes simplex virus 2 primary microRNA Transcript regulation.
Tang S, Bosch-Marce M, Patel A, Margolis TP, Krause PR
J Virol. 2015 May; 89(9)4837-48. doi: 10.1128/JVI.03135-14.

PMID:
    25673716
    [PubMed - indexed for MEDLINE]
Related citations


Retinal detachment associated with AIDS-related cytomegalovirus retinitis: risk factors in a resource-limited setting.
Yen M, Chen J, Ausayakhun S, Kunavisarut P, Vichitvejpaisal P, Ausayakhun S, Jirawison C, Shantha J, Holland GN, Heiden D, Margolis TP, Keenan JD
Am J Ophthalmol. 2015 Jan; 159(1)185-92. doi: 10.1016/j.ajo.2014.10.014.

PMID:
    25448999
    [PubMed - indexed for MEDLINE]
Related citations


Telemedicine screening for cytomegalovirus retinitis at the point of care for human immunodeficiency virus infection.
Jirawison C, Yen M, Leenasirimakul P, Chen J, Guadanant S, Kunavisarut P, Patikulsila D, Watanachai N, Ausayakhun S, Heiden D, Holland GN, Margolis TP, Keenan JD
JAMA Ophthalmol. 2015 Feb; 133(2)198-205. doi: 10.1001/jamaophthalmol.2014.4766.

PMID:
    25412344
    [PubMed - indexed for MEDLINE]
Related citations


Dry eye symptom severity and persistence are associated with symptoms of neuropathic pain.
Galor A, Zlotcavitch L, Walter SD, Felix ER, Feuer W, Martin ER, Margolis TP, Sarantopoulos KD, Levitt RC
Br J Ophthalmol. 2015 May; 99(5)665-8. doi: 10.1136/bjophthalmol-2014-306057.

PMID:
    25336572
    [PubMed - indexed for MEDLINE]
Related citations


The epidemiology of herpes simplex virus eye disease in Northern California.
Stanzel TP, Diaz JD, Mather R, Wong IG, Margolis TP, Gritz DC
Ophthalmic Epidemiol. 2014 Dec; 21(6)370-7. doi: 10.3109/09286586.2014.966848.

PMID:
    25299934
    [PubMed - indexed for MEDLINE]
Related citations


Complications related to a cosmetic eye-whitening procedure.
Vo RC, Stafeeva K, Aldave AJ, Stulting RD, Moore Q, Pflugfelder SC, Chungfat NC, Holsclaw DS, Margolis TP, Deng SX
Am J Ophthalmol. 2014 Nov; 158(5)967-73. doi: 10.1016/j.ajo.2014.07.032.

PMID:
    25072832
    [PubMed - indexed for MEDLINE]
Related citations


Novel telemedicine device for diagnosis of corneal abrasions and ulcers in resource-poor settings.
Maamari RN, Ausayakhun S, Margolis TP, Fletcher DA, Keenan JD
JAMA Ophthalmol. 2014 Jul; 132(7)894-5. doi: 10.1001/jamaophthalmol.2014.335.

PMID:
    25010172
    [PubMed - indexed for MEDLINE]
Related citations


Telemedicine diagnosis of cytomegalovirus retinitis by nonophthalmologists.
Yen M, Ausayakhun S, Chen J, Ausayakhun S, Jirawison C, Heiden D, Holland GN, Margolis TP, Keenan JD
JAMA Ophthalmol. 2014 Sep; 132(9)1052-8. doi: 10.1001/jamaophthalmol.2014.1108.

PMID:
    24945306
    [PubMed - indexed for MEDLINE]
Related citations

In the News

Areas of Research Interest

Herpes simplex infection, varicella zoster infection, ocular pain, molecular diagnostics, cost effective care via telemedicine