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Todd A. Fehniger, MD, PhD

Associate Professor, Medicine
Division of Oncology
Section, Bone Marrow Transplant

Specialty Areas

Oncology
Lymphoma
Bone Marrow Transplant

Board Certifications

Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Lymphoma, cellular therapy and bone marrow transplantation

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 7
Office Phone: 314-454-8304
Fax: 314-454-7551

Education

Education

PhD: Molecular Virology, Immunology, and Medical Genetics, The Ohio State University, College of Medicine and Public Health Columbus, Ohio 2000
BS: Biological Sciences, SUNY, Buffalo, New York 1994
Fellowship: Hematology and Oncology, Washington University School of Medicine, St. Louis, Missouri 2008
Residency: Internal Medicine, Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, Missouri 2004
Medical Degree: The Ohio State University, College of Medicine and Public Health, Columbus, Ohio 2002

Publication & Research

Publication & Research

CD70 turns on NK cells to attack lymphoma.
Fehniger TA
Blood. 2017 Jul 20; 130(3)238-239. doi: 10.1182/blood-2017-06-786244.

PMID:
    28729334
    [PubMed - in process]
Related citations


A Phase I/II Trial of Panobinostat in Combination With Lenalidomide in Patients With Relapsed or Refractory Hodgkin Lymphoma.
Maly JJ, Christian BA, Zhu X, Wei L, Sexton JL, Jaglowski SM, Devine SM, Fehniger TA, Wagner-Johnston ND, Phelps MA, Bartlett NL, Blum KA
Clin Lymphoma Myeloma Leuk. 2017 Jun; 17(6)347-353. doi: 10.1016/j.clml.2017.05.008.

PMID:
    28622959
    [PubMed - in process]
Related citations


T Cell-Replete Peripheral Blood Haploidentical Hematopoietic Cell Transplantation with Post-Transplantation Cyclophosphamide Results in Outcomes Similar to Transplantation from Traditionally Matched Donors in Active Disease Acute Myeloid Leukemia.
How J, Slade M, Vu K, DiPersio JF, Westervelt P, Uy GL, Abboud CN, Vij R, Schroeder MA, Fehniger TA, Romee R
Biol Blood Marrow Transplant. 2017 Apr; 23(4)648-653. doi: 10.1016/j.bbmt.2017.01.068.

PMID:
    28087457
    [PubMed - in process]
Related citations


Single institution experience with G-CSF mobilized T-cell replete haploidentical hematopoietic cell transplantation.
Huselton E, Slade M, DiPersio JF, Westervelt P, Vij R, Uy GL, Fehniger TA, Abboud CN, Gao F, Schroeder MA, Romee R
Bone Marrow Transplant. 2017 May; 52(5)769-771. doi: 10.1038/bmt.2016.354.

PMID:
    28067881
    [PubMed - in process]
Related citations


Recurrent somatic mutations affecting B-cell receptor signaling pathway genes in follicular lymphoma.
Krysiak K, Gomez F, White BS, Matlock M, Miller CA, Trani L, Fronick CC, Fulton RS, Kreisel F, Cashen AF, Carson KR, Berrien-Elliott MM, Bartlett NL, Griffith M, Griffith OL, Fehniger TA
Blood. 2017 Jan 26; 129(4)473-483. doi: 10.1182/blood-2016-07-729954.

PMID:
    28064239
    [PubMed - indexed for MEDLINE]
Related citations


TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes.
Welch JS, Petti AA, Miller CA, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Baty JD, Duncavage EJ, Tandon B, Lee YS, Wartman LD, Uy GL, Ghobadi A, Tomasson MH, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Cashen AF, Schroeder MA, Jacoby MA, Heath SE, Luber K, Janke MR, Hantel A, Khan N, Sukhanova MJ, Knoebel RW, Stock W, Graubert TA, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ
N Engl J Med. 2016 Nov 24; 375(21)2023-2036. doi: 10.1056/NEJMoa1605949.

PMID:
    27959731
    [PubMed - indexed for MEDLINE]
Related citations


Cytokine-Induced Memory-Like Differentiation Enhances Unlicensed Natural Killer Cell Antileukemia and FcγRIIIa-Triggered Responses.
Wagner JA, Berrien-Elliott MM, Rosario M, Leong JW, Jewell BA, Schappe T, Abdel-Latif S, Fehniger TA
Biol Blood Marrow Transplant. 2017 Mar; 23(3)398-404. doi: 10.1016/j.bbmt.2016.11.018.

PMID:
    27894857
    [PubMed - in process]
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Cytomegalovirus viremia, disease, and impact on relapse in T-cell replete peripheral blood haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide.
Goldsmith SR, Slade M, DiPersio JF, Westervelt P, Lawrence SJ, Uy GL, Abboud CN, Vij R, Schroeder MA, Fehniger TA, Dubberke ER, Trinkaus K, Romee R
Haematologica. 2016 Nov; 101(11)e465-e468.

PMID:
    27443287
    [PubMed - in process]
Related citations


Harnessing NK Cell Memory for Cancer Immunotherapy.
Fehniger TA, Cooper MA
Trends Immunol. 2016 Dec; 37(12)877-888. doi: 10.1016/j.it.2016.09.005.

PMID:
    27773685
    [PubMed - indexed for MEDLINE]
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Mir-223 regulates the number and function of myeloid-derived suppressor cells in multiple sclerosis and experimental autoimmune encephalomyelitis.
Cantoni C, Cignarella F, Ghezzi L, Mikesell B, Bollman B, Berrien-Elliott MM, Ireland AR, Fehniger TA, Wu GF, Piccio L
Acta Neuropathol. 2017 Jan; 133(1)61-77. doi: 10.1007/s00401-016-1621-6.

PMID:
    27704281
    [PubMed - in process]
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Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia.
Romee R, Rosario M, Berrien-Elliott MM, Wagner JA, Jewell BA, Schappe T, Leong JW, Abdel-Latif S, Schneider SE, Willey S, Neal CC, Yu L, Oh ST, Lee YS, Mulder A, Claas F, Cooper MA, Fehniger TA
Sci Transl Med. 2016 Sep 21; 8(357)357ra123. doi: 10.1126/scitranslmed.aaf2341.

PMID:
    27655849
    [PubMed - in process]
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Longitudinal Body Composition Changes in Diffuse Large B-cell Lymphoma Survivors: A Retrospective Cohort Study of United States Veterans.
Xiao DY, Luo S, O'Brian K, Sanfilippo KM, Ganti A, Riedell P, Lynch RC, Liu W, Kahl BS, Cashen AF, Fehniger TA, Carson KR
J Natl Cancer Inst. 2016 Nov; 108(11)doi: 10.1093/jnci/djw145.

PMID:
    27381623
    [PubMed - indexed for MEDLINE]
Related citations


Severe Cytokine-Release Syndrome after T Cell-Replete Peripheral Blood Haploidentical Donor Transplantation Is Associated with Poor Survival and Anti-IL-6 Therapy Is Safe and Well Tolerated.
Abboud R, Keller J, Slade M, DiPersio JF, Westervelt P, Rettig MP, Meier S, Fehniger TA, Abboud CN, Uy GL, Vij R, Trinkaus KM, Schroeder MA, Romee R
Biol Blood Marrow Transplant. 2016 Oct; 22(10)1851-1860. doi: 10.1016/j.bbmt.2016.06.010.

PMID:
    27318038
    [PubMed - in process]
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Comparison of Outcomes after Peripheral Blood Haploidentical versus Matched Unrelated Donor Allogeneic Hematopoietic Cell Transplantation in Patients with Acute Myeloid Leukemia: A Retrospective Single-Center Review.
Rashidi A, DiPersio JF, Westervelt P, Vij R, Schroeder MA, Cashen AF, Fehniger TA, Romee R
Biol Blood Marrow Transplant. 2016 Sep; 22(9)1696-1701. doi: 10.1016/j.bbmt.2016.05.010.

PMID:
    27223108
    [PubMed - in process]
Related citations


Human Adaptive Natural Killer Cells: Beyond NKG2C.
Wagner JA, Fehniger TA
Trends Immunol. 2016 Jun; 37(6)351-3. doi: 10.1016/j.it.2016.05.001.

PMID:
    27179621
    [PubMed - indexed for MEDLINE]
Related citations


HLA disparity is not inconsequential in peripheral blood T-replete haploidentical hematopoietic stem cell transplantation.
Rashidi A, DiPersio JF, Westervelt P, Abboud CN, Schroeder MA, Pusic I, Cashen AF, Fehniger TA, Romee R
Bone Marrow Transplant. 2016 Sep; 51(9)1275-8. doi: 10.1038/bmt.2016.117.

PMID:
    27159170
    [PubMed - in process]
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Transcriptional and post-transcriptional regulation of NK cell development and function.
Leong JW, Wagner JA, Ireland AR, Fehniger TA
Clin Immunol. 2017 Apr; 17760-69. doi: 10.1016/j.clim.2016.03.003.

PMID:
    26948928
    [PubMed - indexed for MEDLINE]
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The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas.
Rosario M, Liu B, Kong L, Collins LI, Schneider SE, Chen X, Han K, Jeng EK, Rhode PR, Leong JW, Schappe T, Jewell BA, Keppel CR, Shah K, Hess B, Romee R, Piwnica-Worms DR, Cashen AF, Bartlett NL, Wong HC, Fehniger TA
Clin Cancer Res. 2016 Feb 1; 22(3)596-608. doi: 10.1158/1078-0432.CCR-15-1419.

PMID:
    26423796
    [PubMed - indexed for MEDLINE]
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Improving natural killer cell cancer immunotherapy.
Berrien-Elliott MM, Romee R, Fehniger TA
Curr Opin Organ Transplant. 2015 Dec; 20(6)671-80. doi: 10.1097/MOT.0000000000000243.

PMID:
    26414502
    [PubMed - indexed for MEDLINE]
Related citations


Memory NK Cells Take Out the (Mitochondrial) Garbage.
Wagner JA, Fehniger TA
Immunity. 2015 Aug 18; 43(2)218-20. doi: 10.1016/j.immuni.2015.08.009.

PMID:
    26287678
    [PubMed - indexed for MEDLINE]
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