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Timothy Miller, MD, PhD

David Clayson Professor of Neurology

Specialty Areas

Neurology - Adult
ALS - Lou Gehrig's Disease

Board Certifications


Areas of Clinical Interest

Disease models of ALS, translational neuroscience, novel therapies for neurodegenerative diseases

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Neuroscience Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: 314-362-6981
Fax: 314-362-3752



Medical Degree: Washington University School of Medicine, St. Louis, MO 1998
PhD: Washington University School of Medicine, St. Louis, MO 1998
Residency: Neurology, University of California, San Francisco 2003
Fellowship: Neuromuscular, University of California, San Francisco 2003
BS, BA: University of Virginia, Charlottesville, VA 1991

Publication & Research

Publication & Research

Paganoni S, Hyman T, Shui A, Allred P, Harms M, Liu J, Maragakis N, Schoenfeld D, Yu H, Atassi N, Cudkowicz M, Miller TM. Pre-morbid type 2 diabetes mellitus is not a prognostic factor in amyotrophic lateral sclerosis. Muscle Nerve. 2015 Sep;52(3):339-343. PMID: 25900666

Crisp MJ, Mawuenyega KG, Patterson BW, Reddy NC, Chott R, Self WK, Weihl CC, Jockel-Balsarotti J, Varadhachary AS, Bucelli RC, Yarasheski KE, Bateman RJ, Miller TM. In vivo kinetic approach reveals slow SOD1 turnover in the CNS. The Journal of Clinical Investigation 2015;125(7):2772-2780. PMID: 26075819

Reddy LV, Miller TM. RNA-targeted Therapeutics for ALS. Neurotherapeutics 2015;12(2):424-427. PMCID: 4404448

Sanders DW, Kaufman SK, DeVos SL, Sharma AM, Mirbaha H, Li A, Barker SJ, Foley AC, Thorpe JR, Serpell LC, Miller TM, Grinberg LT, Seeley WW, Diamond MI. Distinct tau prion strains propagate in cells and mice and define different tauopathies. Neuron 2014;82(6):1271-1288. PMCID: 4171396

Cady J, Koval ED, Benitez BA, Zaidman C, Jockel-Balsarotti J, Allred P, Baloh RH, Ravits J, Simpson E, Appel SH, Pestronk A, Goate AM, Miller TM, Cruchaga C, Harms MB. TREM2 variant p.R47H as a risk factor for sporadic amyotrophic lateral sclerosis. JAMA Neurol 2014;71(4):449-453. PMCID: 4087113

Crisp MJ, Beckett J, Coates JR, Miller TM. Canine degenerative myelopathy: biochemical characterization of superoxide dismutase 1 in the first naturally occurring non-human amyotrophic lateral sclerosis model. Exp Neurol 2013;248:1-9. PMCID: 3773294