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Timothy J. Eberlein, MD

Bixby Professor, Surgery
Chairman, Surgery
Spencer T. and Ann W. Olin Distinguished Professor and Director, The Alvin J. Siteman Cancer Center
Surgeon-in-Chief, Barnes-Jewish Hospital

Specialty Areas

Oncologic Surgery
Breast Oncology
Breast Health

Board Certifications

General Surgery

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital
VA Medical Center - St. Louis

Areas of Clinical Interest

Breast cancer, breast surgery

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Breast Health Center

4921 Parkview Place
St. Louis, MO 63110

Suite: F
Floor: 5
Office Phone: 314-362-2280
Fax: 314-454-1898

Education

Education

M.A. (Hon.): Harvard University, Cambridge, Massachusetts 1996
Residency: Surgery, Brigham & Women's Hospital, Boston, Massachusetts 1984
Medical Degree: University Of Pittsburgh, Pittsburgh, Pennsylvania 1977
B.S.: University of Pittsburgh, Pittsburgh, Pennsylvania 1973

Publication & Research

Publication & Research

NeoPalAna: Neoadjuvant Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, and Anastrozole for Clinical Stage 2 or 3 Estrogen Receptor-Positive Breast Cancer.
Ma CX, Gao F, Luo J, Northfelt DW, Goetz M, Forero A, Hoog J, Naughton M, Ademuyiwa F, Suresh R, Anderson KS, Margenthaler J, Aft R, Hobday T, Moynihan T, Gillanders W, Cyr A, Eberlein TJ, Hieken T, Krontiras H, Guo Z, Lee MV, Spies NC, Skidmore ZL, Griffith OL, Griffith M, Thomas S, Bumb C, Vij K, Bartlett CH, Koehler M, Al-Kateb H, Sanati S, Ellis MJ
Clin Cancer Res. 2017 Aug 1; 23(15)4055-4065. doi: 10.1158/1078-0432.CCR-16-3206.

PMID:
    28270497
    [PubMed - in process]
Related citations


Successful Completion of the Pilot Phase of a Randomized Controlled Trial Comparing Sentinel Lymph Node Biopsy to No Further Axillary Staging in Patients with Clinical T1-T2 N0 Breast Cancer and Normal Axillary Ultrasound.
Cyr AE, Tucker N, Ademuyiwa F, Margenthaler JA, Aft RL, Eberlein TJ, Appleton CM, Zoberi I, Thomas MA, Gao F, Gillanders WE
J Am Coll Surg. 2016 Aug; 223(2)399-407. doi: 10.1016/j.jamcollsurg.2016.04.048.

PMID:
    27212005
    [PubMed - indexed for MEDLINE]
Related citations


Key Tenets of Effective Surgery Leadership: Perspectives From the Society of Surgical Chairs Mentorship Sessions.
Rosengart TK, Kent KC, Bland KI, Britt LD, Eberlein TJ, Gewertz BL, Hunter JG, Lillemoe KD, Pellegrini CA, Schulick RD, Stain SC, Weigel RJ
JAMA Surg. 2016 Aug 1; 151(8)768-70. doi: 10.1001/jamasurg.2016.0405.

PMID:
    27096328
    [PubMed - indexed for MEDLINE]
Related citations


Surgical Training and the Early Specialization Program: Analysis of a National Program.
Klingensmith ME, Potts JR, Merrill WH, Eberlein TJ, Rhodes RS, Ashley SW, Valentine RJ, Hunter JG, Stain SC
J Am Coll Surg. 2016 Apr; 222(4)410-6. doi: 10.1016/j.jamcollsurg.2015.12.035.

PMID:
    27016968
    [PubMed - indexed for MEDLINE]
Related citations


Lymphovascular space invasion and lack of downstaging after neoadjuvant chemotherapy are strong predictors of adverse outcome in young women with locally advanced breast cancer.
Khwaja SS, Ivanovich J, DeWees TA, Ochoa L, Mullen DF, Thomas M, Margenthaler JA, Cyr A, Naughton M, Sanati S, Eberlein TJ, Gillanders WE, Aft RL, Zoberi JE, Zoberi I
Cancer Med. 2016 Feb; 5(2)230-8. doi: 10.1002/cam4.586.

PMID:
    26687192
    [PubMed - indexed for MEDLINE]
Related citations


Presidential Forum Discussion: Development of Surgical Scientists.
Weigel RJ, Upchurch GR Jr, Eberlein TJ, Lucas CE
Ann Surg. 2015 Oct; 262(4)555-62. doi: 10.1097/SLA.0000000000001400.

PMID:
    26366534
    [PubMed - indexed for MEDLINE]
Related citations


Delivering High-Quality Cancer Care: The Critical Role of Quality Measurement.
Spinks T, Ganz PA, Sledge GW Jr, Levit L, Hayman JA, Eberlein TJ, Feeley TW
Healthc (Amst). 2014 Mar 1; 2(1)53-62.

PMID:
    24839592
    [PubMed]
Related citations


A new paradigm in surgical training.
Eberlein TJ
J Am Coll Surg. 2014 Apr; 218(4)511-8. doi: 10.1016/j.jamcollsurg.2013.12.045.

PMID:
    24655837
    [PubMed - indexed for MEDLINE]
Related citations


An institutional strategy to increase minority recruitment to therapeutic trials.
Anwuri VV, Hall LE, Mathews K, Springer BC, Tappenden JR, Farria DM, Jackson S, Goodman MS, Eberlein TJ, Colditz GA
Cancer Causes Control. 2013 Oct; 24(10)1797-809. doi: 10.1007/s10552-013-0258-1.

PMID:
    23846282
    [PubMed - indexed for MEDLINE]
Related citations


Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axis.
Sanford DE, Belt BA, Panni RZ, Mayer A, Deshpande AD, Carpenter D, Mitchem JB, Plambeck-Suess SM, Worley LA, Goetz BD, Wang-Gillam A, Eberlein TJ, Denardo DG, Goedegebuure SP, Linehan DC
Clin Cancer Res. 2013 Jul 1; 19(13)3404-15. doi: 10.1158/1078-0432.CCR-13-0525.

PMID:
    23653148
    [PubMed - indexed for MEDLINE]
Related citations


Disease recurrence in sentinel node-positive breast cancer patients forgoing axillary lymph node dissection.
Cyr A, Gao F, Gillanders WE, Aft RL, Eberlein TJ, Margenthaler JA
Ann Surg Oncol. 2012 Oct; 19(10)3185-91. doi: 10.1245/s10434-012-2547-4.

PMID:
    22890591
    [PubMed - indexed for MEDLINE]
Related citations


Shaping a modern academic department of surgery: honoring the past; focusing on the future.
Eberlein TJ
Ann Surg. 2012 Sep; 256(3)395-401. doi: 10.1097/SLA.0b013e3182641299.

PMID:
    22868359
    [PubMed - indexed for MEDLINE]
Related citations


Compromised margins following mastectomy for stage I-III invasive breast cancer.
Yu J, Al Mushawah F, Taylor ME, Cyr AE, Gillanders WE, Aft RL, Eberlein TJ, Gao F, Margenthaler JA
J Surg Res. 2012 Sep; 177(1)102-8. doi: 10.1016/j.jss.2012.03.046.

PMID:
    22520579
    [PubMed - indexed for MEDLINE]
Related citations


Positive margin rates following breast-conserving surgery for stage I-III breast cancer: palpable versus nonpalpable tumors.
Atkins J, Al Mushawah F, Appleton CM, Cyr AE, Gillanders WE, Aft RL, Eberlein TJ, Gao F, Margenthaler JA
J Surg Res. 2012 Sep; 177(1)109-15. doi: 10.1016/j.jss.2012.03.045.

PMID:
    22516344
    [PubMed - indexed for MEDLINE]
Related citations


Neoadjuvant chemotherapy is associated with improved survival compared with adjuvant chemotherapy in patients with triple-negative breast cancer only after complete pathologic response.
Fisher CS, Ma CX, Gillanders WE, Aft RL, Eberlein TJ, Gao F, Margenthaler JA
Ann Surg Oncol. 2012 Jan; 19(1)253-8. doi: 10.1245/s10434-011-1877-y.

PMID:
    21725686
    [PubMed - indexed for MEDLINE]
Related citations


Breast cancer in elderly women (≥ 80 years): variation in standard of care?
Cyr A, Gillanders WE, Aft RL, Eberlein TJ, Margenthaler JA
J Surg Oncol. 2011 Mar 1; 103(3)201-6. doi: 10.1002/jso.21799.

PMID:
    21337547
    [PubMed - indexed for MEDLINE]
Related citations


Consensus statement on the adoption of the COPE guidelines.
Surgery Journal Editors Group.
J Hepatobiliary Pancreat Sci. 2011 Jan; 18(1)125-6. doi: 10.1007/s00534-010-0366-1.

PMID:
    21184116
    [PubMed - indexed for MEDLINE]
Related citations


Are we overtreating papillomas diagnosed on core needle biopsy?
Cyr AE, Novack D, Trinkaus K, Margenthaler JA, Gillanders WE, Eberlein TJ, Ritter J, Aft RL
Ann Surg Oncol. 2011 Apr; 18(4)946-51. doi: 10.1245/s10434-010-1403-7.

PMID:
    21046266
    [PubMed - indexed for MEDLINE]
Related citations


Micrometastatic disease and isolated tumor cells as a predictor for additional breast cancer axillary metastatic burden.
Cyr A, Gillanders WE, Aft RL, Eberlein TJ, Gao F, Margenthaler JA
Ann Surg Oncol. 2010 Oct; 17 Suppl 3303-11. doi: 10.1245/s10434-010-1255-1.

PMID:
    20853051
    [PubMed - indexed for MEDLINE]
Related citations


Induction of Th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer.
Gnerlich JL, Mitchem JB, Weir JS, Sankpal NV, Kashiwagi H, Belt BA, Porembka MR, Herndon JM, Eberlein TJ, Goedegebuure P, Linehan DC
J Immunol. 2010 Oct 1; 185(7)4063-71. doi: 10.4049/jimmunol.0902609.

PMID:
    20805420
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Tumor immunology and immune therapies using T-cells and T-cell subpopulations;tumor/lymphocyte interactions and their role in tumor rejection;Identification of tumor associated antigens; Identification of the co-stimulatory molecules and pathways in human solid tumors. Also, clinical aspects of therapy for sarcomas, melanoma, breast cancer, and malignancies of the GI tract.