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Tiffany M. Osborn, MD, MPH, FACEP

Professor, Surgery
Acute and Critical Care Surgery

Specialty Areas

Burn/Trauma/Surgical Critical Care

Board Certifications

Critical Care ( European Society of Intensive Care Medicine)
Emergency Medicine

Areas of Clinical Interest

Emergency medicine, critical care, trauma

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

Barnes-Jewish Center for Outpatient Health

4901 Forest Park Avenue
St. Louis, MO 63108

Office Phone: 314-362-1272
Fax: 314-362-5743

Barnes-Jewish Hospital

1 Barnes-Jewish Hospital Plaza
St. Louis, MO 63110

Office Phone: 314-362-1272
Fax: 314-362-5743

Education

Education

Masters Degree: (Public Health Research), London School of Hygiene and Tropical Medicine, London, England 2009
Medical School: University of Texas Health Sciences Center, San Antonio TX 1997
Residency: Emergency Medicine, University of Maryland Medical System, Baltimore, MD 2000
Fellowship: Trauma and Surgical Critical Care, R Adams Cowley Shock Trauma Center, Baltimore, MD, 2002

Publication & Research

Publication & Research

Urban and Rural Emergency Department Performance on National Quality Metrics for Sepsis Care in the United States.
Greenwood-Ericksen MB, Rothenberg C, Mohr N, Andrea SD, Slesinger T, Osborn T, Whittle J, Goyal P, Tarrant N, Schuur JD, Yealy DM, Venkatesh A
J Rural Health. 2018 Nov 28; doi: 10.1111/jrh.12339.

PMID:
    30488590
    [PubMed - as supplied by publisher]
Related citations


Mortality Changes Associated with Mandated Public Reporting for Sepsis. The Results of the New York State Initiative.
Levy MM, Gesten FC, Phillips GS, Terry KM, Seymour CW, Prescott HC, Friedrich M, Iwashyna TJ, Osborn T, Lemeshow S
Am J Respir Crit Care Med. 2018 Dec 1; 198(11)1406-1412. doi: 10.1164/rccm.201712-2545OC.

PMID:
    30189749
    [PubMed - in process]
Related citations


A global perspective on vasoactive agents in shock.
Annane D, Ouanes-Besbes L, de Backer D, DU B, Gordon AC, Hernández G, Olsen KM, Osborn TM, Peake S, Russell JA, Cavazzoni SZ
Intensive Care Med. 2018 Jun; 44(6)833-846. doi: 10.1007/s00134-018-5242-5.

PMID:
    29868972
    [PubMed - indexed for MEDLINE]
Related citations


Sepsis in the older person: The ravages of time and bacteria.
Burkett E, Macdonald SP, Carpenter CR, Arendts G, Hullick C, Nagaraj G, Osborn TM
Emerg Med Australas. 2018 Apr; 30(2)249-258. doi: 10.1111/1742-6723.12949.

PMID:
    29569846
    [PubMed - indexed for MEDLINE]
Related citations


Reporting of Sepsis Cases for Performance Measurement Versus for Reimbursement in New York State.
Prescott HC, Cope TM, Gesten FC, Ledneva TA, Friedrich ME, Iwashyna TJ, Osborn TM, Seymour CW, Levy MM
Crit Care Med. 2018 May; 46(5)666-673. doi: 10.1097/CCM.0000000000003005.

PMID:
    29406420
    [PubMed - in process]
Related citations


The New York Sepsis Severity Score: Development of a Risk-Adjusted Severity Model for Sepsis.
Phillips GS, Osborn TM, Terry KM, Gesten F, Levy MM, Lemeshow S
Crit Care Med. 2018 May; 46(5)674-683. doi: 10.1097/CCM.0000000000002824.

PMID:
    29206765
    [PubMed - in process]
Related citations


Preliminary Performance on the New CMS Sepsis-1 National Quality Measure: Early Insights From the Emergency Quality Network (E-QUAL).
Venkatesh AK, Slesinger T, Whittle J, Osborn T, Aaronson E, Rothenberg C, Tarrant N, Goyal P, Yealy DM, Schuur JD
Ann Emerg Med. 2018 Jan; 71(1)10-15.e1. doi: 10.1016/j.annemergmed.2017.06.032.

PMID:
    28789803
    [PubMed - indexed for MEDLINE]
Related citations


Time to Treatment and Mortality during Mandated Emergency Care for Sepsis.
Seymour CW, Gesten F, Prescott HC, Friedrich ME, Iwashyna TJ, Phillips GS, Lemeshow S, Osborn T, Terry KM, Levy MM
N Engl J Med. 2017 Jun 8; 376(23)2235-2244. doi: 10.1056/NEJMoa1703058.

PMID:
    28528569
    [PubMed - indexed for MEDLINE]
Related citations


Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis.
PRISM Investigators., Rowan KM, Angus DC, Bailey M, Barnato AE, Bellomo R, Canter RR, Coats TJ, Delaney A, Gimbel E, Grieve RD, Harrison DA, Higgins AM, Howe B, Huang DT, Kellum JA, Mouncey PR, Music E, Peake SL, Pike F, Reade MC, Sadique MZ, Singer M, Yealy DM
N Engl J Med. 2017 Jun 8; 376(23)2223-2234. doi: 10.1056/NEJMoa1701380.

PMID:
    28320242
    [PubMed - indexed for MEDLINE]
Related citations


Severe Sepsis and Septic Shock Trials (ProCESS, ARISE, ProMISe): What is Optimal Resuscitation?
Osborn TM
Crit Care Clin. 2017 Apr; 33(2)323-344. doi: 10.1016/j.ccc.2016.12.004.

PMID:
    28284298
    [PubMed - indexed for MEDLINE]
Related citations


Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP
Intensive Care Med. 2017 Mar; 43(3)304-377. doi: 10.1007/s00134-017-4683-6.

PMID:
    28101605
    [PubMed - indexed for MEDLINE]
Related citations


Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP
Crit Care Med. 2017 Mar; 45(3)486-552. doi: 10.1097/CCM.0000000000002255.

PMID:
    28098591
    [PubMed - indexed for MEDLINE]
Related citations


Application of a Framework to Assess the Usefulness of Alternative Sepsis Criteria.
Seymour CW, Coopersmith CM, Deutschman CS, Gesten F, Klompas M, Levy M, Martin GS, Osborn TM, Rhee C, Warren DK, Watson RS, Angus DC
Crit Care Med. 2016 Mar; 44(3)e122-30. doi: 10.1097/CCM.0000000000001724.

PMID:
    26901560
    [PubMed - indexed for MEDLINE]
Related citations


A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria.
Angus DC, Seymour CW, Coopersmith CM, Deutschman CS, Klompas M, Levy MM, Martin GS, Osborn TM, Rhee C, Watson RS
Crit Care Med. 2016 Mar; 44(3)e113-21. doi: 10.1097/CCM.0000000000001730.

PMID:
    26901559
    [PubMed - indexed for MEDLINE]
Related citations


Protocolised Management In Sepsis (ProMISe): a multicentre randomised controlled trial of the clinical effectiveness and cost-effectiveness of early, goal-directed, protocolised resuscitation for emerging septic shock.
Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Tan JC, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM
Health Technol Assess. 2015 Nov; 19(97)i-xxv, 1-150. doi: 10.3310/hta19970.

PMID:
    26597979
    [PubMed - indexed for MEDLINE]
Related citations


Trial of early, goal-directed resuscitation for septic shock.
Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM, ProMISe Trial Investigators.
N Engl J Med. 2015 Apr 2; 372(14)1301-11. doi: 10.1056/NEJMoa1500896.

PMID:
    25776532
    [PubMed - indexed for MEDLINE]
Related citations


Lactate measurements in sepsis-induced tissue hypoperfusion: results from the Surviving Sepsis Campaign database.
Casserly B, Phillips GS, Schorr C, Dellinger RP, Townsend SR, Osborn TM, Reinhart K, Selvakumar N, Levy MM
Crit Care Med. 2015 Mar; 43(3)567-73. doi: 10.1097/CCM.0000000000000742.

PMID:
    25479113
    [PubMed - indexed for MEDLINE]
Related citations


Surviving Sepsis Campaign: association between performance metrics and outcomes in a 7.5-year study.
Levy MM, Rhodes A, Phillips GS, Townsend SR, Schorr CA, Beale R, Osborn T, Lemeshow S, Chiche JD, Artigas A, Dellinger RP
Crit Care Med. 2015 Jan; 43(1)3-12. doi: 10.1097/CCM.0000000000000723.

PMID:
    25275252
    [PubMed - indexed for MEDLINE]
Related citations


Surviving Sepsis Campaign: association between performance metrics and outcomes in a 7.5-year study.
Levy MM, Rhodes A, Phillips GS, Townsend SR, Schorr CA, Beale R, Osborn T, Lemeshow S, Chiche JD, Artigas A, Dellinger RP
Intensive Care Med. 2014 Nov; 40(11)1623-33. doi: 10.1007/s00134-014-3496-0.

PMID:
    25270221
    [PubMed - indexed for MEDLINE]
Related citations


Age-related differences in biomarkers of acute inflammation during hospitalization for sepsis.
Ginde AA, Blatchford PJ, Trzeciak S, Hollander JE, Birkhahn R, Otero R, Osborn TM, Moretti E, Nguyen HB, Gunnerson KJ, Milzman D, Gaieski DF, Goyal M, Cairns CB, Rivers EP, Shapiro NI
Shock. 2014 Aug; 42(2)99-107. doi: 10.1097/SHK.0000000000000182.

PMID:
    24978893
    [PubMed - indexed for MEDLINE]
Related citations