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Thomas W. Ferkol Jr., MD

Alexis Hartmann Professor, Pediatrics
Division of Pediatric Allergy, Immunology and Pulmonary Medicine
Director, Division of Pediatric Allergy, Immunology and Pulmonary Medicine

Specialty Areas

Pediatric Pulmonary Disease
Pediatric Asthma
Pediatric Cystic Fibrosis

Board Certifications

Pediatrics
Pediatric Pulmonary Disease

Hospital Affiliations

St. Louis Children's Hospital

Areas of Clinical Interest

Cystic fibrosis, pulmonary inflammation and disease in children

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: Second Floor, Suite C
Office Phone: 314-454-2694
Fax: 314-454-2515

St. Louis Children's Specialty Care Center

13001 North Outer Forty
St. Louis, MO 63017

Suite: 2E
Office Phone: 314-454-2694

Education

Education

Fellowship: Pediatric Pulmonology, Case Western Reserve University, Cleveland, Ohio 1989
Chief Resident: University of North Carolina, Chapel Hill, North Carolina 1989
Residency: Pediatrics, University of North Carolina, Chapel Hill, North Carolina 1988
Medical Degree: Ohio State University College of Medicine, Cleveland, Ohio 1985
B.S.: Case Western Reserve University, Cleveland, Ohio 1981

Publication & Research

Publication & Research

Primary Ciliary Dyskinesia: First Health-related Quality of Life Measures for Pediatric Patients.
Dell SD, Leigh MW, Lucas JS, Ferkol TW, Knowles MR, Alpern A, Behan L, Morris AM, Hogg C, DunnGalvin A, Quittner AL
Ann Am Thorac Soc. 2016 Jul 27;

PMID:
    27464304
    [PubMed - as supplied by publisher]
Related citations


Clinical Features and Associated Likelihood of Primary Ciliary Dyskinesia in Children and Adolescents.
Leigh MW, Ferkol TW, Davis SD, Lee HS, Rosenfeld M, Dell SD, Sagel SD, Milla C, Olivier KN, Sullivan KM, Zariwala MA, Pittman J, Shapiro AJ, Carson JL, Krischer J, Hazucha MJ, Knowles MR
Ann Am Thorac Soc. 2016 Apr 12;

PMID:
    27070726
    [PubMed - as supplied by publisher]
Related citations


Primary ciliary dyskinesia and associated sensory ciliopathies.
Horani A, Ferkol TW
Expert Rev Respir Med. 2016 May; 10(5)569-76. doi: 10.1586/17476348.2016.1165612.

PMID:
    26967669
    [PubMed - in process]
Related citations


Genetics and biology of primary ciliary dyskinesia.
Horani A, Ferkol TW, Dutcher SK, Brody SL
Paediatr Respir Rev. 2016 Mar; 1818-24. doi: 10.1016/j.prrv.2015.09.001.

PMID:
    26476603
    [PubMed - in process]
Related citations


Outcomes and Treatment of Chronic Methicillin-Resistant Staphylococcus aureus Differs by Staphylococcal Cassette Chromosome mec (SCCmec) Type in Children With Cystic Fibrosis.
Heltshe SL, Saiman L, Popowitch EB, Miller MB, Kloster M, Thompson V, Ferkol TW, Hoover WC, Schechter MS, Muhlebach MS
J Pediatric Infect Dis Soc. 2015 Sep; 4(3)225-31. doi: 10.1093/jpids/piu048.

PMID:
    26336603
    [PubMed - in process]
Related citations


Such Are the Impositions of Quackery: E-Cigarettes.
Leone FT, Ferkol TW
Ann Am Thorac Soc. 2015 Jun; 12(6)787-8. doi: 10.1513/AnnalsATS.201504-252ED.

PMID:
    26075549
    [PubMed - indexed for MEDLINE]
Related citations


Use of ibuprofen to assess inflammatory biomarkers in induced sputum: Implications for clinical trials in cystic fibrosis.
Chmiel JF, Konstan MW, Accurso FJ, Lymp J, Mayer-Hamblett N, VanDevanter DR, Rose LM, Ramsey BW, Assessment of Induced Sputum in Cystic Fibrosis Study Group
J Cyst Fibros. 2015 Nov; 14(6)720-6. doi: 10.1016/j.jcf.2015.03.007.

PMID:
    25869324
    [PubMed - in process]
Related citations


Response to Snijders et al.
Horani A, Brody SL, Ferkol TW
Pediatr Res. 2014 Sep; 76(3)322. doi: 10.1038/pr.2014.80.

PMID:
    24933009
    [PubMed - indexed for MEDLINE]
Related citations


L-plastin is essential for alveolar macrophage production and control of pulmonary pneumococcal infection.
Deady LE, Todd EM, Davis CG, Zhou JY, Topcagic N, Edelson BT, Ferkol TW, Cooper MA, Muenzer JT, Morley SC
Infect Immun. 2014 May; 82(5)1982-93. doi: 10.1128/IAI.01199-13.

PMID:
    24595139
    [PubMed - indexed for MEDLINE]
Related citations


Picking up speed: advances in the genetics of primary ciliary dyskinesia.
Horani A, Brody SL, Ferkol TW
Pediatr Res. 2014 Jan; 75(1-2)158-64. doi: 10.1038/pr.2013.200.

PMID:
    24192704
    [PubMed - indexed for MEDLINE]
Related citations


FDG PET imaging in cystic fibrosis.
Chen DL, Atkinson JJ, Ferkol TW
Semin Nucl Med. 2013 Nov; 43(6)412-9. doi: 10.1053/j.semnuclmed.2013.06.002.

PMID:
    24094708
    [PubMed - indexed for MEDLINE]
Related citations


CCDC65 mutation causes primary ciliary dyskinesia with normal ultrastructure and hyperkinetic cilia.
Horani A, Brody SL, Ferkol TW, Shoseyov D, Wasserman MG, Ta-shma A, Wilson KS, Bayly PV, Amirav I, Cohen-Cymberknoh M, Dutcher SK, Elpeleg O, Kerem E
PLoS One. 2013; 8(8)e72299. doi: 10.1371/journal.pone.0072299.

PMID:
    23991085
    [PubMed - indexed for MEDLINE]
Related citations


LRRC6 mutation causes primary ciliary dyskinesia with dynein arm defects.
Horani A, Ferkol TW, Shoseyov D, Wasserman MG, Oren YS, Kerem B, Amirav I, Cohen-Cymberknoh M, Dutcher SK, Brody SL, Elpeleg O, Kerem E
PLoS One. 2013; 8(3)e59436. doi: 10.1371/journal.pone.0059436.

PMID:
    23527195
    [PubMed - indexed for MEDLINE]
Related citations


Primary ciliary dyskinesia-causing mutations in Amish and Mennonite communities.
Ferkol TW, Puffenberger EG, Lie H, Helms C, Strauss KA, Bowcock A, Carson JL, Hazucha M, Morton DH, Patel AC, Leigh MW, Knowles MR, Zariwala MA
J Pediatr. 2013 Aug; 163(2)383-7. doi: 10.1016/j.jpeds.2013.01.061.

PMID:
    23477994
    [PubMed - indexed for MEDLINE]
Related citations


Whole-exome capture and sequencing identifies HEATR2 mutation as a cause of primary ciliary dyskinesia.
Horani A, Druley TE, Zariwala MA, Patel AC, Levinson BT, Van Arendonk LG, Thornton KC, Giacalone JC, Albee AJ, Wilson KS, Turner EH, Nickerson DA, Shendure J, Bayly PV, Leigh MW, Knowles MR, Brody SL, Dutcher SK, Ferkol TW
Am J Hum Genet. 2012 Oct 5; 91(4)685-93. doi: 10.1016/j.ajhg.2012.08.022.

PMID:
    23040496
    [PubMed - indexed for MEDLINE]
Related citations


Ciliopathies: the central role of cilia in a spectrum of pediatric disorders.
Ferkol TW, Leigh MW
J Pediatr. 2012 Mar; 160(3)366-71. doi: 10.1016/j.jpeds.2011.11.024.

PMID:
    22177992
    [PubMed - indexed for MEDLINE]
Related citations


Effect of polarized release of CXC-chemokines from wild-type and cystic fibrosis murine airway epithelial cells.
Farberman MM, Ibricevic A, Joseph TD, Akers KT, Garcia-Medina R, Crosby S, Clarke LL, Brody SL, Ferkol TW
Am J Respir Cell Mol Biol. 2011 Aug; 45(2)221-8. doi: 10.1165/rcmb.2009-0249OC.

PMID:
    20639462
    [PubMed - indexed for MEDLINE]
Related citations


Primary ciliary dyskinesia in Amish communities.
Lie H, Zariwala MA, Helms C, Bowcock AM, Carson JL, Brown DE 3rd, Hazucha MJ, Forsen J, Molter D, Knowles MR, Leigh MW, Ferkol TW
J Pediatr. 2010 Jun; 156(6)1023-5. doi: 10.1016/j.jpeds.2010.01.054.

PMID:
    20350728
    [PubMed - indexed for MEDLINE]
Related citations


Aquagenic wrinkling of the palms in cystic fibrosis: comparison with controls and genotype-phenotype correlations.
Berk DR, Ciliberto HM, Sweet SC, Ferkol TW, Bayliss SJ
Arch Dermatol. 2009 Nov; 145(11)1296-9. doi: 10.1001/archdermatol.2009.260.

PMID:
    19917960
    [PubMed - indexed for MEDLINE]
Related citations


Panton-Valentine Leukocidin-positive methicillin-resistant Staphylococcus aureus lung infection in patients with cystic fibrosis.
Elizur A, Orscheln RC, Ferkol TW, Atkinson JJ, Dunne WM Jr, Buller RS, Armstrong JR, Mardis ER, Storch GA, Cannon CL
Chest. 2007 Jun; 131(6)1718-25.

PMID:
    17400676
    [PubMed - indexed for MEDLINE]
Related citations