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Thomas John Baranski, MD, PhD

Associate Professor, Medicine
Division of Endocrinology, Diabetes and Metabolism
Assistant Professor, Molecular Biology and Pharmacology

Specialty Areas

Diabetes
Endocrinology
Metabolism

Board Certifications

Endocrinology, Diabetes and Metabolism
Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Endocrinology, metabolism, diabetes

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Medicine Multispecialty Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 5
Office Phone: 314-362-3500
Fax: 314-747-2460

Education

Education

Fellowship: Diabetes, Endocrinology and Metabolism, University of California, San Francisco, California 1998
Residency: University of California, San Francisco, California 1994
Ph.D.: Washington University School of Medicine 1992
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1992
B.S.: University of Wisconsin, Madison, Wisconsin 1985

Publication & Research

Publication & Research

CoA protects against the deleterious effects of caloric overload in Drosophila.
Palanker Musselman L, Fink JL, Baranski TJ
J Lipid Res. 2016 Mar; 57(3)380-7. doi: 10.1194/jlr.M062976.

PMID:
    26805007
    [PubMed - in process]
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BRAF mutation is not predictive of long-term outcome in papillary thyroid carcinoma.
Henke LE, Pfeifer JD, Ma C, Perkins SM, DeWees T, El-Mofty S, Moley JF, Nussenbaum B, Haughey BH, Baranski TJ, Schwarz JK, Grigsby PW
Cancer Med. 2015 Jun; 4(6)791-9. doi: 10.1002/cam4.417.

PMID:
    25712893
    [PubMed - indexed for MEDLINE]
Related citations


Transformed Drosophila cells evade diet-mediated insulin resistance through wingless signaling.
Hirabayashi S, Baranski TJ, Cagan RL
Cell. 2013 Aug 1; 154(3)664-75. doi: 10.1016/j.cell.2013.06.030.

PMID:
    23911328
    [PubMed - indexed for MEDLINE]
Related citations


Evidence for transgenerational metabolic programming in Drosophila.
Buescher JL, Musselman LP, Wilson CA, Lang T, Keleher M, Baranski TJ, Duncan JG
Dis Model Mech. 2013 Sep; 6(5)1123-32. doi: 10.1242/dmm.011924.

PMID:
    23649823
    [PubMed - indexed for MEDLINE]
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Frizzled receptors signal through G proteins.
Nichols AS, Floyd DH, Bruinsma SP, Narzinski K, Baranski TJ
Cell Signal. 2013 Jun; 25(6)1468-75. doi: 10.1016/j.cellsig.2013.03.009.

PMID:
    23524329
    [PubMed - indexed for MEDLINE]
Related citations


A Drosophila functional evaluation of candidates from human genome-wide association studies of type 2 diabetes and related metabolic traits identifies tissue-specific roles for dHHEX.
Pendse J, Ramachandran PV, Na J, Narisu N, Fink JL, Cagan RL, Collins FS, Baranski TJ
BMC Genomics. 2013 Feb 27; 14136. doi: 10.1186/1471-2164-14-136.

PMID:
    23445342
    [PubMed - indexed for MEDLINE]
Related citations


Role of fat body lipogenesis in protection against the effects of caloric overload in Drosophila.
Musselman LP, Fink JL, Ramachandran PV, Patterson BW, Okunade AL, Maier E, Brent MR, Turk J, Baranski TJ
J Biol Chem. 2013 Mar 22; 288(12)8028-42. doi: 10.1074/jbc.M112.371047.

PMID:
    23355467
    [PubMed - indexed for MEDLINE]
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A Drosophila model of high sugar diet-induced cardiomyopathy.
Na J, Musselman LP, Pendse J, Baranski TJ, Bodmer R, Ocorr K, Cagan R
PLoS Genet. 2013; 9(1)e1003175. doi: 10.1371/journal.pgen.1003175.

PMID:
    23326243
    [PubMed - indexed for MEDLINE]
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Best practices and pearls in interdisciplinary mentoring from Building Interdisciplinary Research Careers in Women's Health Directors.
Guise JM, Nagel JD, Regensteiner JG, Building Interdisciplinary Research Careers in Women’s Health Directors
J Womens Health (Larchmt). 2012 Nov; 21(11)1114-27. doi: 10.1089/jwh.2012.3788.

PMID:
    22994986
    [PubMed - indexed for MEDLINE]
Related citations


Structural mechanisms of constitutive activation in the C5a receptors with mutations in the extracellular loops: molecular modeling study.
Nikiforovich GV, Baranski TJ
Proteins. 2012 Jan; 80(1)71-80. doi: 10.1002/prot.23162.

PMID:
    21960464
    [PubMed - indexed for MEDLINE]
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Interdisciplinary research career development: building interdisciplinary research careers in women's health program best practices.
Domino SE, Bodurtha J, Nagel JD, BIRCWH Program Leadership
J Womens Health (Larchmt). 2011 Nov; 20(11)1587-601. doi: 10.1089/jwh.2011.3165.

PMID:
    21923414
    [PubMed - indexed for MEDLINE]
Related citations


Difference between restoring and predicting 3D structures of the loops in G-protein-coupled receptors by molecular modeling.
Nikiforovich GV, Taylor CM, Marshall GR, Baranski TJ
Proc Natl Acad Sci U S A. 2011 Jul 26; 108(30)E341; author reply E342. doi: 10.1073/pnas.1107702108.

PMID:
    21724986
    [PubMed - indexed for MEDLINE]
Related citations


A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila.
Musselman LP, Fink JL, Narzinski K, Ramachandran PV, Hathiramani SS, Cagan RL, Baranski TJ
Dis Model Mech. 2011 Nov; 4(6)842-9. doi: 10.1242/dmm.007948.

PMID:
    21719444
    [PubMed - indexed for MEDLINE]
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Thyroid cancer: what to do after fine needle aspiration.
Rometo DA, Baranski TJ
Mo Med. 2011 Mar-Apr; 108(2)93-8.

PMID:
    21568229
    [PubMed - indexed for MEDLINE]
Related citations


Simplified modeling approach suggests structural mechanisms for constitutive activation of the C5a receptor.
Nikiforovich GV, Marshall GR, Baranski TJ
Proteins. 2011 Mar; 79(3)787-802. doi: 10.1002/prot.22918.

PMID:
    21287612
    [PubMed - indexed for MEDLINE]
Related citations


Computational modeling of constitutively active mutants of GPCRs C5a receptor.
Nikiforovich GV, Baranski TJ
Methods Enzymol. 2010; 485369-91. doi: 10.1016/B978-0-12-381296-4.00021-X.

PMID:
    21050928
    [PubMed - indexed for MEDLINE]
Related citations


Electron paramagnetic resonance studies of functionally active, nitroxide spin-labeled peptide analogues of the C-terminus of a G-protein alpha subunit.
Van Eps N, Anderson LL, Kisselev OG, Baranski TJ, Hubbell WL, Marshall GR
Biochemistry. 2010 Aug 17; 49(32)6877-86. doi: 10.1021/bi100846c.

PMID:
    20695526
    [PubMed - indexed for MEDLINE]
Related citations


Third extracellular loop (EC3)-N terminus interaction is important for seven-transmembrane domain receptor function: implications for an activation microswitch region.
Rana S, Baranski TJ
J Biol Chem. 2010 Oct 8; 285(41)31472-83. doi: 10.1074/jbc.M110.129213.

PMID:
    20663868
    [PubMed - indexed for MEDLINE]
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Structural models for the complex of chemotaxis inhibitory protein of Staphylococcus aureus with the C5a receptor.
Nikiforovich GV, Baranski TJ
Biochem Biophys Res Commun. 2009 Dec 18; 390(3)481-4. doi: 10.1016/j.bbrc.2009.09.113.

PMID:
    19799858
    [PubMed - indexed for MEDLINE]
Related citations


Modeling the possible conformations of the extracellular loops in G-protein-coupled receptors.
Nikiforovich GV, Taylor CM, Marshall GR, Baranski TJ
Proteins. 2010 Feb 1; 78(2)271-85. doi: 10.1002/prot.22537.

PMID:
    19731375
    [PubMed - indexed for MEDLINE]
Related citations