Patient Portal

Tanner Johanns, MD, PhD

Instructor, Medicine
Medical Oncology

Specialty Areas

Medical Oncology
Neuro Oncology
Skin Cancer

Board Certifications

Internal Medicine
Medical Oncology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Immunotherapy clinical trials, primary brain tumors and brain metastases, melanoma, merkel cell carcinoma. 

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Siteman Cancer Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 7
Office Phone: 314-747-1171
Fax: 314-362-3192

Education

Education

Research Fellowship, Medical Oncology: Washington University School of Medicine, St. Louis, MO 2018
Fellowship, Medical Oncology: Washington University School of Medicine, St. Louis, MO 2015
Residency, Internal Medicine: Barnes-Jewish Hospital, St. Louis, MO 2014
Medical Degree: University of Minnesota, Minneapolis, MN 2012
PhD, Immunology: University of Minnesota, Minneapolis, MN 2010

Publication & Research

Publication & Research

Late Effects of Radiation Prime the Brain Microenvironment for Accelerated Tumor Growth.
Duan C, Yang R, Yuan L, Engelbach JA, Tsien CI, Rich KM, Dahiya SM, Johanns TM, Ackerman JJH, Garbow JR
Int J Radiat Oncol Biol Phys. 2019 Jan 1; 103(1)190-194. doi: 10.1016/j.ijrobp.2018.08.033.

PMID:
    30171879
    [PubMed - in process]
Related citations


Stereotactic radiosurgery and immunotherapy in melanoma brain metastases: Patterns of care and treatment outcomes.
Gabani P, Fischer-Valuck BW, Johanns TM, Hernandez-Aya LF, Keller JW, Rich KM, Kim AH, Dunn GP, Robinson CG, Chicoine MR, Huang J, Abraham CD
Radiother Oncol. 2018 Aug; 128(2)266-273. doi: 10.1016/j.radonc.2018.06.017.

PMID:
    29960685
    [PubMed - indexed for MEDLINE]
Related citations


BRAF-Targeted Therapy in the Treatment of <i>BRAF</i>-Mutant High-Grade Gliomas in Adults.
Johanns TM, Ansstas G, Dahiya S
J Natl Compr Canc Netw. 2018 Apr; 16(4)451-454. doi: 10.6004/jnccn.2018.7029.

PMID:
    29632063
    [PubMed - in process]
Related citations


Use of extracranial radiation therapy in metastatic melanoma patients receiving immunotherapy.
Gabani P, Robinson CG, Ansstas G, Johanns TM, Huang J
Radiother Oncol. 2018 May; 127(2)310-317. doi: 10.1016/j.radonc.2018.02.022.

PMID:
    29534829
    [PubMed - indexed for MEDLINE]
Related citations


T-Cell Exhaustion Signatures Vary with Tumor Type and Are Severe in Glioblastoma.
Woroniecka K, Chongsathidkiet P, Rhodin K, Kemeny H, Dechant C, Farber SH, Elsamadicy AA, Cui X, Koyama S, Jackson C, Hansen LJ, Johanns TM, Sanchez-Perez L, Chandramohan V, Yu YA, Bigner DD, Giles A, Healy P, Dranoff G, Weinhold KJ, Dunn GP, Fecci PE
Clin Cancer Res. 2018 Sep 1; 24(17)4175-4186. doi: 10.1158/1078-0432.CCR-17-1846.

PMID:
    29437767
    [PubMed - in process]
Related citations


Cancer immunogenomic approach to neoantigen discovery in a checkpoint blockade responsive murine model of oral cavity squamous cell carcinoma.
Zolkind P, Przybylski D, Marjanovic N, Nguyen L, Lin T, Johanns T, Alexandrov A, Zhou L, Allen CT, Miceli AP, Schreiber RD, Artyomov M, Dunn GP, Uppaluri R
Oncotarget. 2018 Jan 9; 9(3)4109-4119. doi: 10.18632/oncotarget.23751.

PMID:
    29423108
    [PubMed]
Related citations


Rapid Clinical and Radiographic Response With Combined Dabrafenib and Trametinib in Adults With <i>BRAF</i>-Mutated High-Grade Glioma.
Johanns TM, Ferguson CJ, Grierson PM, Dahiya S, Ansstas G
J Natl Compr Canc Netw. 2018 Jan; 16(1)4-10. doi: 10.6004/jnccn.2017.7032.

PMID:
    29295876
    [PubMed - in process]
Related citations


Management of intracranial melanomas in the era of precision medicine.
Young GJ, Bi WL, Wu WW, Johanns TM, Dunn GP, Dunn IF
Oncotarget. 2017 Oct 24; 8(51)89326-89347. doi: 10.18632/oncotarget.19223.

PMID:
    29179523
    [PubMed]
Related citations


Comprehensive Analysis of Hypermutation in Human Cancer.
Campbell BB, Light N, Fabrizio D, Zatzman M, Fuligni F, de Borja R, Davidson S, Edwards M, Elvin JA, Hodel KP, Zahurancik WJ, Suo Z, Lipman T, Wimmer K, Kratz CP, Bowers DC, Laetsch TW, Dunn GP, Johanns TM, Grimmer MR, Smirnov IV, Larouche V, Samuel D, Bronsema A, Osborn M, Stearns D, Raman P, Cole KA, Storm PB, Yalon M, Opocher E, Mason G, Thomas GA, Sabel M, George B, Ziegler DS, Lindhorst S, Issai VM, Constantini S, Toledano H, Elhasid R, Farah R, Dvir R, Dirks P, Huang A, Galati MA, Chung J, Ramaswamy V, Irwin MS, Aronson M, Durno C, Taylor MD, Rechavi G, Maris JM, Bouffet E, Hawkins C, Costello JF, Meyn MS, Pursell ZF, Malkin D, Tabori U, Shlien A
Cell. 2017 Nov 16; 171(5)1042-1056.e10. doi: 10.1016/j.cell.2017.09.048.

PMID:
    29056344
    [PubMed - indexed for MEDLINE]
Related citations


Targeting Neoantigens in Glioblastoma: An Overview of Cancer Immunogenomics and Translational Implications.
Johanns TM, Bowman-Kirigin JA, Liu C, Dunn GP
Neurosurgery. 2017 Sep 1; 64(CN_suppl_1)165-176. doi: 10.1093/neuros/nyx321.

PMID:
    28899059
    [PubMed]
Related citations


Applied Cancer Immunogenomics: Leveraging Neoantigen Discovery in Glioblastoma.
Johanns TM, Dunn GP
Cancer J. 2017 Mar/Apr; 23(2)125-130. doi: 10.1097/PPO.0000000000000247.

PMID:
    28410300
    [PubMed - indexed for MEDLINE]
Related citations


Immune checkpoint inhibition in patients with brain metastases.
Johanns T, Waqar SN, Morgensztern D
Ann Transl Med. 2016 Oct; 4(Suppl 1)S9.

PMID:
    27867977
    [PubMed]
Related citations


Immunogenomics of Hypermutated Glioblastoma: A Patient with Germline POLE Deficiency Treated with Checkpoint Blockade Immunotherapy.
Johanns TM, Miller CA, Dorward IG, Tsien C, Chang E, Perry A, Uppaluri R, Ferguson C, Schmidt RE, Dahiya S, Ansstas G, Mardis ER, Dunn GP
Cancer Discov. 2016 Nov; 6(11)1230-1236.

PMID:
    27683556
    [PubMed - indexed for MEDLINE]
Related citations


Endogenous Neoantigen-Specific CD8 T Cells Identified in Two Glioblastoma Models Using a Cancer Immunogenomics Approach.
Johanns TM, Ward JP, Miller CA, Wilson C, Kobayashi DK, Bender D, Fu Y, Alexandrov A, Mardis ER, Artyomov MN, Schreiber RD, Dunn GP
Cancer Immunol Res. 2016 Dec; 4(12)1007-1015.

PMID:
    27799140
    [PubMed - indexed for MEDLINE]
Related citations


High incidence of TERT mutation in brain tumor cell lines.
Johanns TM, Fu Y, Kobayashi DK, Mei Y, Dunn IF, Mao DD, Kim AH, Dunn GP
Brain Tumor Pathol. 2016 Jul; 33(3)222-7. doi: 10.1007/s10014-016-0257-5.

PMID:
    26960334
    [PubMed - indexed for MEDLINE]
Related citations


Selective culling of high avidity antigen-specific CD4+ T cells after virulent Salmonella infection.
Ertelt JM, Johanns TM, Mysz MA, Nanton MR, Rowe JH, Aguilera MN, Way SS
Immunology. 2011 Dec; 134(4)487-97. doi: 10.1111/j.1365-2567.2011.03510.x.

PMID:
    22044420
    [PubMed - indexed for MEDLINE]
Related citations


Early eradication of persistent Salmonella infection primes antibody-mediated protective immunity to recurrent infection.
Johanns TM, Law CY, Kalekar LA, O'Donnell H, Ertelt JM, Rowe JH, Way SS
Microbes Infect. 2011 Apr; 13(4)322-30. doi: 10.1016/j.micinf.2010.11.004.

PMID:
    21134485
    [PubMed - indexed for MEDLINE]
Related citations


Regulatory T cell suppressive potency dictates the balance between bacterial proliferation and clearance during persistent Salmonella infection.
Johanns TM, Ertelt JM, Rowe JH, Way SS
PLoS Pathog. 2010 Aug 12; 6(8)e1001043. doi: 10.1371/journal.ppat.1001043.

PMID:
    20714351
    [PubMed - indexed for MEDLINE]
Related citations


Interleukin (IL)-21-independent pathogen-specific CD8+ T-cell expansion, and IL-21-dependent suppression of CD4+ T-cell IL-17 production.
Ertelt JM, Johanns TM, Rowe JH, Way SS
Immunology. 2010 Oct; 131(2)183-91. doi: 10.1111/j.1365-2567.2010.03287.x.

PMID:
    20465570
    [PubMed - indexed for MEDLINE]
Related citations


Naturally occurring altered peptide ligands control Salmonella-specific CD4+ T cell proliferation, IFN-gamma production, and protective potency.
Johanns TM, Ertelt JM, Lai JC, Rowe JH, Avant RA, Way SS
J Immunol. 2010 Jan 15; 184(2)869-76. doi: 10.4049/jimmunol.0901804.

PMID:
    20026741
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Understanding mechanism of immune evasion in the brain; investigating mechanism of action of novel immunotherapies.