Patient Portal

Steven L. Brody, MD

Dorothy R. and Hubert C. Moog Professor of Pulmonary Medicine
Division of Pulmonary and Critical Care Medicine

Specialty Areas

Pulmonary Disease
Gene Therapy

Board Certifications

Critical Care Medicine
Internal Medicine
Pulmonary Disease
Emergency Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Critical care medicine, ARDS, septic shock, clinical toxicology, cystic fibrosis, primary ciliary dyskinesia

  • Education
  • Publication & Research

Education

Education

Fellowship: Pulmonary Medicine, National Institute of Health, Bethesda, Maryland 1994
Residency: Internal Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio 1983
Medical Degree: University Of Michigan Medical School, Ann Arbor, Michigan 1980
B.S.: Michigan State University, Lyman Briggs Residential College, East Lansing, Michigan 1976

Publication & Research

Publication & Research

Quantification of image texture in X-ray phase-contrast-enhanced projection images of in vivo mouse lungs observed at varied inflation pressures.
Brooks FJ, Gunsten SP, Vasireddi SK, Brody SL, Anastasio MA
Physiol Rep. 2019 Aug; 7(16)e14208. doi: 10.14814/phy2.14208.

PMID:
    31444862
    [PubMed - in process]
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Autophagy proteins are required for club cell structure and function in airways.
Malvin NP, Kern JT, Liu TC, Brody SL, Stappenbeck TS
Am J Physiol Lung Cell Mol Physiol. 2019 Aug 1; 317(2)L259-L270. doi: 10.1152/ajplung.00394.2018.

PMID:
    31116580
    [PubMed - in process]
Related citations


Regulation of cilia abundance in multiciliated cells.
Nanjundappa R, Kong D, Shim K, Stearns T, Brody SL, Loncarek J, Mahjoub MR
Elife. 2019 Apr 26; 8pii: e44039. doi: 10.7554/eLife.44039.

PMID:
    31025935
    [PubMed - in process]
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An obligatory role for club cells in preventing obliterative bronchiolitis in lung transplants.
Liu Z, Liao F, Scozzi D, Furuya Y, Pugh KN, Hachem R, Chen DL, Cano M, Green JM, Krupnick AS, Kreisel D, Perl AKT, Huang HJ, Brody SL, Gelman AE
JCI Insight. 2019 Apr 16; 5pii: 124732. doi: 10.1172/jci.insight.124732.

PMID:
    30990794
    [PubMed - in process]
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Frequenting Sequencing: How Genetics Teaches us Cilia Biology.
Horani A, Brody SL
Am J Respir Cell Mol Biol. 2019 Apr 5; doi: 10.1165/rcmb.2019-0103ED.

PMID:
    30951371
    [PubMed - as supplied by publisher]
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Molecular Imaging Visualizes Recruitment of Inflammatory Monocytes and Macrophages to the Injured Heart.
Heo GS, Kopecky B, Sultan D, Ou M, Feng G, Bajpai G, Zhang X, Luehmann H, Detering L, Su Y, Leuschner F, Combadière C, Kreisel D, Gropler RJ, Brody SL, Liu Y, Lavine KJ
Circ Res. 2019 Mar 15; 124(6)881-890. doi: 10.1161/CIRCRESAHA.118.314030.

PMID:
    30661445
    [PubMed - in process]
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Technical Considerations for Lung Transplantation in Kartagener's Syndrome.
Gauthier JM, Takahashi T, Bierhals AJ, Brody SL, Hachem RR, Witt CA, Byers DE, Yusen RD, Trulock EP, Aguilar PR, Nava RG, Kozower BD, Meyers BF, Patterson GA, Kreisel D, Puri V
Ann Thorac Surg. 2019 May; 107(5)e337-e339. doi: 10.1016/j.athoracsur.2018.08.095.

PMID:
    30612988
    [PubMed - in process]
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A liquid-like organelle at the root of motile ciliopathy.
Huizar RL, Lee C, Boulgakov AA, Horani A, Tu F, Marcotte EM, Brody SL, Wallingford JB
Elife. 2018 Dec 18; 7pii: e38497. doi: 10.7554/eLife.38497.

PMID:
    30561330
    [PubMed - indexed for MEDLINE]
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Intracellular C3 Protects Human Airway Epithelial Cells from Stress-associated Cell Death.
Kulkarni HS, Elvington ML, Perng YC, Liszewski MK, Byers DE, Farkouh C, Yusen RD, Lenschow DJ, Brody SL, Atkinson JP
Am J Respir Cell Mol Biol. 2019 Feb; 60(2)144-157. doi: 10.1165/rcmb.2017-0405OC.

PMID:
    30156437
    [PubMed - in process]
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Blood Exposure Causes Ventricular Zone Disruption and Glial Activation In Vitro.
Castaneyra-Ruiz L, Morales DM, McAllister JP, Brody SL, Isaacs AM, Strahle JM, Dahiya SM, Limbrick DD
J Neuropathol Exp Neurol. 2018 Sep 1; 77(9)803-813. doi: 10.1093/jnen/nly058.

PMID:
    30032242
    [PubMed - in process]
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Quantifying Ciliary Dynamics during Assembly Reveals Stepwise Waveform Maturation in Airway Cells.
Oltean A, Schaffer AJ, Bayly PV, Brody SL
Am J Respir Cell Mol Biol. 2018 Oct; 59(4)511-522. doi: 10.1165/rcmb.2017-0436OC.

PMID:
    29851510
    [PubMed - indexed for MEDLINE]
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Visualization of Monocytic Cells in Regressing Atherosclerotic Plaques by Intravital 2-Photon and Positron Emission Tomography-Based Imaging-Brief Report.
Li W, Luehmann HP, Hsiao HM, Tanaka S, Higashikubo R, Gauthier JM, Sultan D, Lavine KJ, Brody SL, Gelman AE, Gropler RJ, Liu Y, Kreisel D
Arterioscler Thromb Vasc Biol. 2018 May; 38(5)1030-1036. doi: 10.1161/ATVBAHA.117.310517.

PMID:
    29567678
    [PubMed - indexed for MEDLINE]
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Development of Fully Degradable Phosphonium-Functionalized Amphiphilic Diblock Copolymers for Nucleic Acids Delivery.
Borguet YP, Khan S, Noel A, Gunsten SP, Brody SL, Elsabahy M, Wooley KL
Biomacromolecules. 2018 Apr 9; 19(4)1212-1222. doi: 10.1021/acs.biomac.8b00069.

PMID:
    29526096
    [PubMed - indexed for MEDLINE]
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Establishment of the early cilia preassembly protein complex during motile ciliogenesis.
Horani A, Ustione A, Huang T, Firth AL, Pan J, Gunsten SP, Haspel JA, Piston DW, Brody SL
Proc Natl Acad Sci U S A. 2018 Feb 6; 115(6)E1221-E1228. doi: 10.1073/pnas.1715915115.

PMID:
    29358401
    [PubMed - indexed for MEDLINE]
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The complement system in the airway epithelium: An overlooked host defense mechanism and therapeutic target?
Kulkarni HS, Liszewski MK, Brody SL, Atkinson JP
J Allergy Clin Immunol. 2018 May; 141(5)1582-1586.e1. doi: 10.1016/j.jaci.2017.11.046.

PMID:
    29339260
    [PubMed - indexed for MEDLINE]
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Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation.
Dickinson JD, Sweeter JM, Warren KJ, Ahmad IM, De Deken X, Zimmerman MC, Brody SL
Redox Biol. 2018 Apr; 14272-284. doi: 10.1016/j.redox.2017.09.013.

PMID:
    28982074
    [PubMed - indexed for MEDLINE]
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17β-Estradiol Dysregulates Innate Immune Responses to Pseudomonas aeruginosa Respiratory Infection and Is Modulated by Estrogen Receptor Antagonism.
Abid S, Xie S, Bose M, Shaul PW, Terada LS, Brody SL, Thomas PJ, Katzenellenbogen JA, Kim SH, Greenberg DE, Jain R
Infect Immun. 2017 Oct; 85(10)pii: e00422-17. doi: 10.1128/IAI.00422-17.

PMID:
    28784925
    [PubMed - indexed for MEDLINE]
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Harnessing TGF-β and BMP signaling for expansion of p63-positive epithelial stem cells.
Brody SL, Kaiko GE
Stem Cell Investig. 2016; 382. doi: 10.21037/sci.2016.10.13.

PMID:
    28066784
    [PubMed]
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PET-based Imaging of Chemokine Receptor 2 in Experimental and Disease-related Lung Inflammation.
Liu Y, Gunsten SP, Sultan DH, Luehmann HP, Zhao Y, Blackwell TS, Bollermann-Nowlis Z, Pan JH, Byers DE, Atkinson JJ, Kreisel D, Holtzman MJ, Gropler RJ, Combadiere C, Brody SL
Radiology. 2017 Jun; 283(3)758-768. doi: 10.1148/radiol.2016161409.

PMID:
    28045644
    [PubMed - indexed for MEDLINE]
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Noninvasive Imaging of CCR2<sup>+</sup> Cells in Ischemia-Reperfusion Injury After Lung Transplantation.
Liu Y, Li W, Luehmann HP, Zhao Y, Detering L, Sultan DH, Hsiao HM, Krupnick AS, Gelman AE, Combadiere C, Gropler RJ, Brody SL, Kreisel D
Am J Transplant. 2016 Oct; 16(10)3016-3023. doi: 10.1111/ajt.13907.

PMID:
    27273836
    [PubMed - indexed for MEDLINE]
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