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Stephanie Markovina, MD, PhD

Assistant Professor, Radiation Oncology

Specialty Areas

Gynecologic Oncology
Anal Cancer
Thyroid Cancer

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Gynecologic oncology, thyroid cancer, anal cancer and brachytherapy.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Siteman Cancer Center - South County

5225 MidAmerica Plaza
St. Louis, MO 63129
Phone: 314-747-7222

Office Phone: 314-747-7222
Additional Phone: 800-600-3606

Center for Advanced Medicine
Radiation Oncology Center

4921 Parkview Place
St. Louis, MO 63110

Suite: LL

Education

Education

Residency, Radiation Oncology: Washington University School of Medicine, St. Louis, MO 2015
Medical Degree: University of Wisconsin School of Medicine & Public Health, Madison, WI 2011
PhD, Cellular and Molecular Biology: University of Wisconsin Madison, Madison, WI 2008
BS, Biology: Washington University, St. Louis, MO 2001

Publication & Research

Publication & Research

Improved Metastasis- and Disease-Free Survival With Preoperative Sequential Short-Course Radiation Therapy and FOLFOX Chemotherapy for Rectal Cancer Compared With Neoadjuvant Long-Course Chemoradiotherapy: Results of a Matched Pair Analysis.
Markovina S, Youssef F, Roy A, Aggarwal S, Khwaja S, DeWees T, Tan B, Hunt S, Myerson RJ, Chang DT, Parikh PJ, Olsen JR
Int J Radiat Oncol Biol Phys. 2017 Oct 1; 99(2)417-426. doi: 10.1016/j.ijrobp.2017.05.048.

PMID:
    28871992
    [PubMed - in process]
Related citations


Improved survival with definitive chemoradiation compared to definitive radiation alone in squamous cell carcinoma of the vulva: A review of the National Cancer Database.
Rao YJ, Chin RI, Hui C, Mutch DG, Powell MA, Schwarz JK, Grigsby PW, Markovina S
Gynecol Oncol. 2017 Sep; 146(3)572-579. doi: 10.1016/j.ygyno.2017.06.022.

PMID:
    28662775
    [PubMed - indexed for MEDLINE]
Related citations


Quality of Life Outcomes From a Phase 2 Trial of Short-Course Radiation Therapy Followed by FOLFOX Chemotherapy as Preoperative Treatment for Rectal Cancer.
Khwaja SS, Roy A, Markovina S, Dewees TA, Hunt S, Tan B, Myerson RJ, Olsen JR, Parikh PJ
Int J Radiat Oncol Biol Phys. 2016 Aug 1; 95(5)1429-38. doi: 10.1016/j.ijrobp.2016.03.020.

PMID:
    27209506
    [PubMed - indexed for MEDLINE]
Related citations


Regional Lymph Node Uptake of [(18)F]Fluorodeoxyglucose After Definitive Chemoradiation Therapy Predicts Local-Regional Failure of Locally Advanced Non-Small Cell Lung Cancer: Results of ACRIN 6668/RTOG 0235.
Markovina S, Duan F, Snyder BS, Siegel BA, Machtay M, Bradley JD
Int J Radiat Oncol Biol Phys. 2015 Nov 1; 93(3)597-605. doi: 10.1016/j.ijrobp.2015.04.026.

PMID:
    26461002
    [PubMed - indexed for MEDLINE]
Related citations


Rebuttal to Drs. Hussein and Cooperberg.
Markovina S, Michalski J
Brachytherapy. 2015 Nov-Dec; 14(6)763-5. doi: 10.1016/j.brachy.2015.06.010.

PMID:
    26235200
    [PubMed - indexed for MEDLINE]
Related citations


Counterpoint: Unfair comparisons lead to unwarranted conclusions-Can treatment modalities for localized prostate cancer truly be compared without bias?
Markovina S, Michalski J
Brachytherapy. 2015 Nov-Dec; 14(6)756-60. doi: 10.1016/j.brachy.2015.06.009.

PMID:
    26219833
    [PubMed - indexed for MEDLINE]
Related citations


Low incidence of new biochemical hypogonadism after intensity modulated radiation therapy for prostate cancer.
Markovina S, Weschenfelder DC, Gay H, McCandless A, Carey B, DeWees T, Knutson N, Michalski J
Pract Radiat Oncol. 2014 Nov-Dec; 4(6)430-6. doi: 10.1016/j.prro.2014.02.004.

PMID:
    25407866
    [PubMed - indexed for MEDLINE]
Related citations


Radiation therapy dose escalation for glioblastoma multiforme in the era of temozolomide.
Badiyan SN, Markovina S, Simpson JR, Robinson CG, DeWees T, Tran DD, Linette G, Jalalizadeh R, Dacey R, Rich KM, Chicoine MR, Dowling JL, Leuthardt EC, Zipfel GJ, Kim AH, Huang J
Int J Radiat Oncol Biol Phys. 2014 Nov 15; 90(4)877-85. doi: 10.1016/j.ijrobp.2014.07.014.

PMID:
    25257812
    [PubMed - indexed for MEDLINE]
Related citations


Acetyl-L-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network.
Callander N, Markovina S, Eickhoff J, Hutson P, Campbell T, Hematti P, Go R, Hegeman R, Longo W, Williams E, Asimakopoulos F, Miyamoto S
Cancer Chemother Pharmacol. 2014 Oct; 74(4)875-82. doi: 10.1007/s00280-014-2550-5.

PMID:
    25168296
    [PubMed - indexed for MEDLINE]
Related citations


Treatment approach, surveillance, and outcome of well-differentiated thyroid cancer in childhood and adolescence.
Markovina S, Grigsby PW, Schwarz JK, DeWees T, Moley JF, Siegel BA, Perkins SM
Thyroid. 2014 Jul; 24(7)1121-6. doi: 10.1089/thy.2013.0297.

PMID:
    24731094
    [PubMed - indexed for MEDLINE]
Related citations


Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-kappaB activity in myeloma cells.
Markovina S, Callander NS, O'Connor SL, Xu G, Shi Y, Leith CP, Kim K, Trivedi P, Kim J, Hematti P, Miyamoto S
Mol Cancer. 2010 Jul 6; 9176. doi: 10.1186/1476-4598-9-176.

PMID:
    20604947
    [PubMed - indexed for MEDLINE]
Related citations


Common variable immunodeficiency with regulatory T-cell deficiency treated with rapamycin.
Simonson WT, Markovina S, Grossman WJ, Lokuta MA, Doan AT, Seroogy CM, Huttenlocher A
Ann Allergy Asthma Immunol. 2009 Feb; 102(2)170-1. doi: 10.1016/S1081-1206(10)60251-7.

PMID:
    19230472
    [PubMed - indexed for MEDLINE]
Related citations


Bortezomib-resistant nuclear factor-kappaB activity in multiple myeloma cells.
Markovina S, Callander NS, O'Connor SL, Kim J, Werndli JE, Raschko M, Leith CP, Kahl BS, Kim K, Miyamoto S
Mol Cancer Res. 2008 Aug; 6(8)1356-64. doi: 10.1158/1541-7786.MCR-08-0108.

PMID:
    18708367
    [PubMed - indexed for MEDLINE]
Related citations


Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma.
Yang DT, Young KH, Kahl BS, Markovina S, Miyamoto S
Mol Cancer. 2008 May 19; 740. doi: 10.1186/1476-4598-7-40.

PMID:
    18489772
    [PubMed - indexed for MEDLINE]
Related citations


DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells.
Mishra MV, Bisht KS, Sun L, Muldoon-Jacobs K, Awwad R, Kaushal A, Nguyen P, Huang L, Pennington JD, Markovina S, Bradbury CM, Gius D
Mol Cancer Res. 2008 Feb; 6(2)243-9. doi: 10.1158/1541-7786.MCR-07-0373.

PMID:
    18314485
    [PubMed - indexed for MEDLINE]
Related citations


Evidence for a phosphorylation-independent role for Ser 32 and 36 in proteasome inhibitor-resistant (PIR) IkappaBalpha degradation in B cells.
O'Connor S, Markovina S, Miyamoto S
Exp Cell Res. 2005 Jul 1; 307(1)15-25.

PMID:
    15922723
    [PubMed - indexed for MEDLINE]
Related citations


Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.
Bisht KS, Bradbury CM, Mattson D, Kaushal A, Sowers A, Markovina S, Ortiz KL, Sieck LK, Isaacs JS, Brechbiel MW, Mitchell JB, Neckers LM, Gius D
Cancer Res. 2003 Dec 15; 63(24)8984-95.

PMID:
    14695217
    [PubMed - indexed for MEDLINE]
Related citations


Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation.
Karimpour S, Lou J, Lin LL, Rene LM, Lagunas L, Ma X, Karra S, Bradbury CM, Markovina S, Goswami PC, Spitz DR, Hirota K, Kalvakolanu DV, Yodoi J, Gius D
Oncogene. 2002 Sep 12; 21(41)6317-27.

PMID:
    12214272
    [PubMed - indexed for MEDLINE]
Related citations


Indomethacin-induced radiosensitization and inhibition of ionizing radiation-induced NF-kappaB activation in HeLa cells occur via a mechanism involving p38 MAP kinase.
Bradbury CM, Markovina S, Wei SJ, Rene LM, Zoberi I, Horikoshi N, Gius D
Cancer Res. 2001 Oct 15; 61(20)7689-96.

PMID:
    11606413
    [PubMed - indexed for MEDLINE]
Related citations


Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation.
Wei SJ, Botero A, Hirota K, Bradbury CM, Markovina S, Laszlo A, Spitz DR, Goswami PC, Yodoi J, Gius D
Cancer Res. 2000 Dec 1; 60(23)6688-95.

PMID:
    11118054
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Cancer biology