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Sharon Cresci, MD

Associate Professor, Medicine
Division of Cardiovascular Diseases

Specialty Areas

Cardiology
Echocardiography
Hypertrophic Cardiomyopathy
Cardiovascular Disease

Board Certifications

Cardiology
Internal Medicine
Echocardiography

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Physician Referral Required

Areas of Clinical Interest

Transthoracic, transesophageal and stress echocardiograms

  • Education
  • Publication & Research

Education

Education

Fellowship: Cardiovascular, Barnes-Jewish/Washington University School of Medicine, St. Louis, Missouri 1997
Fellowship: Cardiology, Bellevue Hospital, New York University Medical Center, New York, New York 1991
Sr. Chief Resident: Department of Medicine, Bellevue Hospital, New York University Medical Center, New York, New York 1990
Medical Degree: New York University Medical Center, New York, New York 1986
B.S.: Biochemistry, State University of New York at Binghamton, Binghamton, New York 1982

Publication & Research

Publication & Research

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.
Zewinger S, Kleber ME, Tragante V, McCubrey RO, Schmidt AF, Direk K, Laufs U, Werner C, Koenig W, Rothenbacher D, Mons U, Breitling LP, Brenner H, Jennings RT, Petrakis I, Triem S, Klug M, Filips A, Blankenberg S, Waldeyer C, Sinning C, Schnabel RB, Lackner KJ, Vlachopoulou E, Nygård O, Svingen GFT, Pedersen ER, Tell GS, Sinisalo J, Nieminen MS, Laaksonen R, Trompet S, Smit RAJ, Sattar N, Jukema JW, Groesdonk HV, Delgado G, Stojakovic T, Pilbrow AP, Cameron VA, Richards AM, Doughty RN, Gong Y, Cooper-DeHoff R, Johnson J, Scholz M, Beutner F, Thiery J, Smith JG, Vilmundarson RO, McPherson R, Stewart AFR, Cresci S, Lenzini PA, Spertus JA, Olivieri O, Girelli D, Martinelli NI, Leiherer A, Saely CH, Drexel H, Mündlein A, Braund PS, Nelson CP, Samani NJ, Kofink D, Hoefer IE, Pasterkamp G, Quyyumi AA, Ko YA, Hartiala JA, Allayee H, Tang WHW, Hazen SL, Eriksson N, Held C, Hagström E, Wallentin L, Åkerblom A, Siegbahn A, Karp I, Labos C, Pilote L, Engert JC, Brophy JM, Thanassoulis G, Bogaty P, Szczeklik W, Kaczor M, Sanak M, Virani SS, Ballantyne CM, Lee VV, Boerwinkle E, Holmes MV, Horne BD, Hingorani A, Asselbergs FW, Patel RS, GENIUS-CHD consortium., Krämer BK, Scharnagl H, Fliser D, März W, Speer T
Lancet Diabetes Endocrinol. 2017 Jul; 5(7)534-543. doi: 10.1016/S2213-8587(17)30096-7.

PMID:
    28566218
    [PubMed - in process]
Related citations


Change in Angina Symptom Status After Acute Myocardial Infarction and Its Association With Readmission Risk: An Analysis of the Translational Research Investigating Underlying Disparities in Acute Myocardial Infarction Patients' Health Status (TRIUMPH) Registry.
Doll JA, Tang F, Cresci S, Ho PM, Maddox TM, Spertus JA, Wang TY
J Am Heart Assoc. 2016 Jun 13; 5(6)pii: e003205. doi: 10.1161/JAHA.116.003205.

PMID:
    27412898
    [PubMed - indexed for MEDLINE]
Related citations


A framework for detecting unfolding emergencies using humans as sensors.
Avvenuti M, Cimino MG, Cresci S, Marchetti A, Tesconi M
Springerplus. 2016; 543. doi: 10.1186/s40064-016-1674-y.

PMID:
    26811805
    [PubMed]
Related citations


Association of Smoking Status With Angina and Health-Related Quality of Life After Acute Myocardial Infarction.
Buchanan DM, Arnold SV, Gosch KL, Jones PG, Longmore LS, Spertus JA, Cresci S
Circ Cardiovasc Qual Outcomes. 2015 Sep; 8(5)493-500.

PMID:
    26307130
    [PubMed - indexed for MEDLINE]
Related citations


Utility of a genetic risk score to predict recurrent cardiovascular events 1 year after an acute coronary syndrome: A pooled analysis of the RISCA, PRAXY, and TRIUMPH cohorts.
Labos C, Martinez SC, Leo Wang RH, Lenzini PA, Pilote L, Bogaty P, Brophy JM, Engert JC, Cresci S, Thanassoulis G
Atherosclerosis. 2015 Sep; 242(1)261-7. doi: 10.1016/j.atherosclerosis.2015.07.029.

PMID:
    26232166
    [PubMed - indexed for MEDLINE]
Related citations


Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project.
Auer PL, Nalls M, Meschia JF, Worrall BB, Longstreth WT Jr, Seshadri S, Kooperberg C, Burger KM, Carlson CS, Carty CL, Chen WM, Cupples LA, DeStefano AL, Fornage M, Hardy J, Hsu L, Jackson RD, Jarvik GP, Kim DS, Lakshminarayan K, Lange LA, Manichaikul A, Quinlan AR, Singleton AB, Thornton TA, Nickerson DA, Peters U, Rich SS, National Heart, Lung, and Blood Institute Exome Sequencing Project.
JAMA Neurol. 2015 Jul; 72(7)781-8. doi: 10.1001/jamaneurol.2015.0582.

PMID:
    25961151
    [PubMed - indexed for MEDLINE]
Related citations


Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.
Do R, Stitziel NO, Won HH, Jørgensen AB, Duga S, Angelica Merlini P, Kiezun A, Farrall M, Goel A, Zuk O, Guella I, Asselta R, Lange LA, Peloso GM, Auer PL, NHLBI Exome Sequencing Project., Girelli D, Martinelli N, Farlow DN, DePristo MA, Roberts R, Stewart AF, Saleheen D, Danesh J, Epstein SE, Sivapalaratnam S, Hovingh GK, Kastelein JJ, Samani NJ, Schunkert H, Erdmann J, Shah SH, Kraus WE, Davies R, Nikpay M, Johansen CT, Wang J, Hegele RA, Hechter E, Marz W, Kleber ME, Huang J, Johnson AD, Li M, Burke GL, Gross M, Liu Y, Assimes TL, Heiss G, Lange EM, Folsom AR, Taylor HA, Olivieri O, Hamsten A, Clarke R, Reilly DF, Yin W, Rivas MA, Donnelly P, Rossouw JE, Psaty BM, Herrington DM, Wilson JG, Rich SS, Bamshad MJ, Tracy RP, Cupples LA, Rader DJ, Reilly MP, Spertus JA, Cresci S, Hartiala J, Tang WH, Hazen SL, Allayee H, Reiner AP, Carlson CS, Kooperberg C, Jackson RD, Boerwinkle E, Lander ES, Schwartz SM, Siscovick DS, McPherson R, Tybjaerg-Hansen A, Abecasis GR, Watkins H, Nickerson DA, Ardissino D, Sunyaev SR, O'Donnell CJ, Altshuler D, Gabriel S, Kathiresan S
Nature. 2015 Feb 5; 518(7537)102-6. doi: 10.1038/nature13917.

PMID:
    25487149
    [PubMed - indexed for MEDLINE]
Related citations


Inactivating mutations in NPC1L1 and protection from coronary heart disease.
Myocardial Infarction Genetics Consortium Investigators., Stitziel NO, Won HH, Morrison AC, Peloso GM, Do R, Lange LA, Fontanillas P, Gupta N, Duga S, Goel A, Farrall M, Saleheen D, Ferrario P, König I, Asselta R, Merlini PA, Marziliano N, Notarangelo MF, Schick U, Auer P, Assimes TL, Reilly M, Wilensky R, Rader DJ, Hovingh GK, Meitinger T, Kessler T, Kastrati A, Laugwitz KL, Siscovick D, Rotter JI, Hazen SL, Tracy R, Cresci S, Spertus J, Jackson R, Schwartz SM, Natarajan P, Crosby J, Muzny D, Ballantyne C, Rich SS, O'Donnell CJ, Abecasis G, Sunaev S, Nickerson DA, Buring JE, Ridker PM, Chasman DI, Austin E, Kullo IJ, Weeke PE, Shaffer CM, Bastarache LA, Denny JC, Roden DM, Palmer C, Deloukas P, Lin DY, Tang ZZ, Erdmann J, Schunkert H, Danesh J, Marrugat J, Elosua R, Ardissino D, McPherson R, Watkins H, Reiner AP, Wilson JG, Altshuler D, Gibbs RA, Lander ES, Boerwinkle E, Gabriel S, Kathiresan S
N Engl J Med. 2014 Nov 27; 371(22)2072-82. doi: 10.1056/NEJMoa1405386.

PMID:
    25390462
    [PubMed - indexed for MEDLINE]
Related citations


Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results.
Tabor HK, Auer PL, Jamal SM, Chong JX, Yu JH, Gordon AS, Graubert TA, O'Donnell CJ, Rich SS, Nickerson DA, NHLBI Exome Sequencing Project., Bamshad MJ
Am J Hum Genet. 2014 Aug 7; 95(2)183-93. doi: 10.1016/j.ajhg.2014.07.006.

PMID:
    25087612
    [PubMed - indexed for MEDLINE]
Related citations


Clinical outcomes associated with proton pump inhibitor use among clopidogrel-treated patients within CYP2C19 genotype groups following acute myocardial infarction.
Depta JP, Lenzini PA, Lanfear DE, Wang TY, Spertus JA, Bach RG, Cresci S
Pharmacogenomics J. 2015 Feb; 15(1)20-5. doi: 10.1038/tpj.2014.28.

PMID:
    25001880
    [PubMed - indexed for MEDLINE]
Related citations


Cytochrome p450 gene variants, race, and mortality among clopidogrel-treated patients after acute myocardial infarction.
Cresci S, Depta JP, Lenzini PA, Li AY, Lanfear DE, Province MA, Spertus JA, Bach RG
Circ Cardiovasc Genet. 2014 Jun; 7(3)277-86. doi: 10.1161/CIRCGENETICS.113.000303.

PMID:
    24762860
    [PubMed - indexed for MEDLINE]
Related citations


Association between diabetes mellitus and angina after acute myocardial infarction: analysis of the TRIUMPH prospective cohort study.
Arnold SV, Spertus JA, Lipska KJ, Tang F, Goyal A, McGuire DK, Cresci S, Maddox TM, Kosiborod M
Eur J Prev Cardiol. 2015 Jun; 22(6)779-87. doi: 10.1177/2047487314533622.

PMID:
    24740679
    [PubMed - indexed for MEDLINE]
Related citations


CHRNA5 variant predicts smoking cessation in patients with acute myocardial infarction.
Chen LS, Bach RG, Lenzini PA, Spertus JA, Bierut LJ, Cresci S
Nicotine Tob Res. 2014 Sep; 16(9)1224-31. doi: 10.1093/ntr/ntu059.

PMID:
    24727484
    [PubMed - indexed for MEDLINE]
Related citations


Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.
Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang ZZ, Bizon C, Lange EM, Smith JD, Turner EH, Jun G, Kang HM, Peloso G, Auer P, Li KP, Flannick J, Zhang J, Fuchsberger C, Gaulton K, Lindgren C, Locke A, Manning A, Sim X, Rivas MA, Holmen OL, Gottesman O, Lu Y, Ruderfer D, Stahl EA, Duan Q, Li Y, Durda P, Jiao S, Isaacs A, Hofman A, Bis JC, Correa A, Griswold ME, Jakobsdottir J, Smith AV, Schreiner PJ, Feitosa MF, Zhang Q, Huffman JE, Crosby J, Wassel CL, Do R, Franceschini N, Martin LW, Robinson JG, Assimes TL, Crosslin DR, Rosenthal EA, Tsai M, Rieder MJ, Farlow DN, Folsom AR, Lumley T, Fox ER, Carlson CS, Peters U, Jackson RD, van Duijn CM, Uitterlinden AG, Levy D, Rotter JI, Taylor HA, Gudnason V Jr, Siscovick DS, Fornage M, Borecki IB, Hayward C, Rudan I, Chen YE, Bottinger EP, Loos RJ, Sætrom P, Hveem K, Boehnke M, Groop L, McCarthy M, Meitinger T, Ballantyne CM, Gabriel SB, O'Donnell CJ, Post WS, North KE, Reiner AP, Boerwinkle E, Psaty BM, Altshuler D, Kathiresan S, Lin DY, Jarvik GP, Cupples LA, Kooperberg C, Wilson JG, Nickerson DA, Abecasis GR, Rich SS, Tracy RP, Willer CJ, NHLBI Grand Opportunity Exome Sequencing Project.
Am J Hum Genet. 2014 Feb 6; 94(2)233-45. doi: 10.1016/j.ajhg.2014.01.010.

PMID:
    24507775
    [PubMed - indexed for MEDLINE]
Related citations


Joint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia.
Rosenthal EA, Ranchalis J, Crosslin DR, Burt A, Brunzell JD, Motulsky AG, Nickerson DA, NHLBI GO Exome Sequencing Project., Wijsman EM, Jarvik GP
Am J Hum Genet. 2013 Dec 5; 93(6)1035-45. doi: 10.1016/j.ajhg.2013.10.019.

PMID:
    24268658
    [PubMed - indexed for MEDLINE]
Related citations


Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections.
Guo DC, Regalado E, Casteel DE, Santos-Cortez RL, Gong L, Kim JJ, Dyack S, Horne SG, Chang G, Jondeau G, Boileau C, Coselli JS, Li Z, Leal SM, Shendure J, Rieder MJ, Bamshad MJ, Nickerson DA, GenTAC Registry Consortium., National Heart, Lung, and Blood Institute Grand Opportunity Exome Sequencing Project., Kim C, Milewicz DM
Am J Hum Genet. 2013 Aug 8; 93(2)398-404. doi: 10.1016/j.ajhg.2013.06.019.

PMID:
    23910461
    [PubMed - indexed for MEDLINE]
Related citations


Insulin resistance is associated with significant clinical atherosclerosis in nondiabetic patients with acute myocardial infarction.
Karrowni W, Li Y, Jones PG, Cresci S, Abdallah MS, Lanfear DE, Maddox TM, McGuire DK, Spertus JA, Horwitz PA
Arterioscler Thromb Vasc Biol. 2013 Sep; 33(9)2245-51. doi: 10.1161/ATVBAHA.113.301585.

PMID:
    23868937
    [PubMed - indexed for MEDLINE]
Related citations


Fine-scale patterns of population stratification confound rare variant association tests.
O'Connor TD, Kiezun A, Bamshad M, Rich SS, Smith JD, Turner E, NHLBIGO Exome Sequencing Project., ESP Population Genetics, Statistical Analysis Working Group., Leal SM, Akey JM
PLoS One. 2013; 8(7)e65834. doi: 10.1371/journal.pone.0065834.

PMID:
    23861739
    [PubMed - indexed for MEDLINE]
Related citations


Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project.
Johnsen JM, Auer PL, Morrison AC, Jiao S, Wei P, Haessler J, Fox K, McGee SR, Smith JD, Carlson CS, Smith N, Boerwinkle E, Kooperberg C, Nickerson DA, Rich SS, Green D, Peters U, Cushman M, Reiner AP, NHLBI Exome Sequencing Project.
Blood. 2013 Jul 25; 122(4)590-7. doi: 10.1182/blood-2013-02-485094.

PMID:
    23690449
    [PubMed - indexed for MEDLINE]
Related citations


Exome sequencing and genome-wide linkage analysis in 17 families illustrate the complex contribution of TTN truncating variants to dilated cardiomyopathy.
Norton N, Li D, Rampersaud E, Morales A, Martin ER, Zuchner S, Guo S, Gonzalez M, Hedges DJ, Robertson PD, Krumm N, Nickerson DA, Hershberger RE, National Heart, Lung, and Blood Institute GO Exome Sequencing Project and the Exome Sequencing Project Family Studies Project Team.
Circ Cardiovasc Genet. 2013 Apr; 6(2)144-53. doi: 10.1161/CIRCGENETICS.111.000062.

PMID:
    23418287
    [PubMed - indexed for MEDLINE]
Related citations