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Sandor J. Kovacs, PhD, MD

Professor, Medicine
Division of Cardiovascular Diseases
Adjunct Professor, Physics
Adjunct Professor, Biomedical and Biological Engineering
Director, Cardiovasculat Biophysics Laboratory

Specialty Areas

Cardiovascular Disease
Cardiology
Cardiac Catheterization
Interventional Cardiology

Board Certifications

Cardiology
Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Physician Referral Required

Areas of Clinical Interest

Cardiology, diastolic function, congestive heart failure, magnetic resonance imaging, hypertension, myocardial ischemia, cardiac catheterization, echocardiography

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish Hospital

1 Barnes-Jewish Hospital Plaza
St. Louis, MO 63110

Office Phone: 314-362-2284

Education

Education

Fellowship: Cardiology, Barnes Hospital, Washington University School of Medicine, St. Louis, Missouri 1985
Residency: Internal Medicine, Barnes Hospital, Washington University School of Medicine, St. Louis, Missouri 1982
Medical Degree: University of Miami, Miami, Florida 1979
Ph.D.: Physics, California Institute of Technology 1977
M.S.: Physics, California Institute of Technology 1972
B.S.: Engineering, Cornell University, Ithaca, New York 1969

Publication & Research

Publication & Research

Quantifying Diastolic Function: From E-Waves as Triangles to Physiologic Contours via the 'Geometric Method'.
Golman M, Padovano W, Shmuylovich L, Kovács SJ
Cardiovasc Eng Technol. 2018 Jan 16; doi: 10.1007/s13239-017-0339-5.

PMID:
    29340885
    [PubMed - as supplied by publisher]
Related citations


Functional Contribution of Circumferential Versus Longitudinal Strain: Different Concepts Suggest Conflicting Results.
Carlsson M, Heiberg E, Ostenfeld E, Steding-Ehrenborg K, Kovács SJ, Flachskampf F, Arheden H
J Am Coll Cardiol. 2018 Jan 16; 71(2)254-255. doi: 10.1016/j.jacc.2017.09.1156.

PMID:
    29325646
    [PubMed - in process]
Related citations


Challenges and opportunities in the development of medical therapies for pediatric populations and the role of extrapolation.
IQ consortium - CPLG Pediatric Working Group., Barrett JS, Bishai R, Bucci-Rechtweg C, Cheung S, Corriol-Rohou S, Haertter S, James A, Kovacs SJ, Liu J, Potempa D, Strougo A, Vanevski K
Clin Pharmacol Ther. 2017 Dec 26; doi: 10.1002/cpt.1000.

PMID:
    29277892
    [PubMed - as supplied by publisher]
Related citations


The quest for load-independent left ventricular chamber properties: exploring the normalized pressure-volume loop.
Kohli K, Kovács SJ
Physiol Rep. 2017 Mar; 5(6)pii: e13160. doi: 10.14814/phy2.13160.

PMID:
    28351966
    [PubMed - indexed for MEDLINE]
Related citations


Hydraulic forces contribute to left ventricular diastolic filling.
Maksuti E, Carlsson M, Arheden H, Kovács SJ, Broomé M, Ugander M
Sci Rep. 2017 Mar 3; 743505. doi: 10.1038/srep43505.

PMID:
    28256604
    [PubMed - in process]
Related citations


Applying a technology-based system for weight loss in adults with obesity.
Rogers RJ, Lang W, Barone Gibbs B, Davis KK, Burke LE, Kovacs SJ, Portzer LA, Jakicic JM
Obes Sci Pract. 2016 Mar; 2(1)3-12.

PMID:
    27812375
    [PubMed]
Related citations


Randomized, Open-Label Study of the Pharmacokinetics and Safety of Oral and Intravenous Administration of Omadacycline to Healthy Subjects.
Sun H, Ting L, Machineni S, Praestgaard J, Kuemmell A, Stein DS, Sunkara G, Kovacs SJ, Villano S, Tanaka SK
Antimicrob Agents Chemother. 2016 Dec; 60(12)7431-7435.

PMID:
    27736760
    [PubMed - indexed for MEDLINE]
Related citations


Clinical disposition, metabolism and in vitro drug-drug interaction properties of omadacycline.
Flarakos J, Du Y, Gu H, Wang L, Einolf HJ, Chun DY, Zhu B, Alexander N, Natrillo A, Hanna I, Ting L, Zhou W, Dole K, Sun H, Kovacs SJ, Stein DS, Tanaka SK, Villano S, Mangold JB
Xenobiotica. 2017 Aug; 47(8)682-696. doi: 10.1080/00498254.2016.1213465.

PMID:
    27499331
    [PubMed - indexed for MEDLINE]
Related citations


Vortex ring behavior provides the epigenetic blueprint for the human heart.
Arvidsson PM, Kovács SJ, Töger J, Borgquist R, Heiberg E, Carlsson M, Arheden H
Sci Rep. 2016 Feb 26; 622021. doi: 10.1038/srep22021.

PMID:
    26915473
    [PubMed - indexed for MEDLINE]
Related citations


Vortex-ring mixing as a measure of diastolic function of the human heart: Phantom validation and initial observations in healthy volunteers and patients with heart failure.
Töger J, Kanski M, Arvidsson PM, Carlsson M, Kovács SJ, Borgquist R, Revstedt J, Söderlind G, Arheden H, Heiberg E
J Magn Reson Imaging. 2016 Jun; 43(6)1386-97. doi: 10.1002/jmri.25111.

PMID:
    26663607
    [PubMed - indexed for MEDLINE]
Related citations


The impact of 6 weeks of atrial fibrillation on left atrial and ventricular structure and function.
Kazui T, Henn MC, Watanabe Y, Kovács SJ, Lawrance CP, Greenberg JW, Moon M, Schuessler RB, Damiano RJ Jr
J Thorac Cardiovasc Surg. 2015 Dec; 150(6)1602-8. doi: 10.1016/j.jtcvs.2015.08.105.

PMID:
    26432717
    [PubMed - indexed for MEDLINE]
Related citations


Letter to the Editor: Atrioventricular plane displacement is not the sole mechanism of atrial and ventricular refill.
Arvidsson PM, Carlsson M, Kovács SJ, Arheden H
Am J Physiol Heart Circ Physiol. 2015 Sep 15; 309(6)H1094-6. doi: 10.1152/ajpheart.00483.2015.

PMID:
    26374902
    [PubMed - indexed for MEDLINE]
Related citations


What global diastolic function is, what it is not, and how to measure it.
Chung CS, Shmuylovich L, Kovács SJ
Am J Physiol Heart Circ Physiol. 2015 Nov; 309(9)H1392-406. doi: 10.1152/ajpheart.00436.2015.

PMID:
    26320035
    [PubMed - indexed for MEDLINE]
Related citations


Quantitative assessment of atrial conduit function: a new index of diastolic dysfunction.
Nappo R, Degiovanni A, Bolzani V, Sartori C, Di Giovine G, Cerini P, Fossaceca R, Kovács SJ, Marino PN
Clin Res Cardiol. 2016 Jan; 105(1)17-28. doi: 10.1007/s00392-015-0882-8.

PMID:
    26123829
    [PubMed - indexed for MEDLINE]
Related citations


Early detection of abnormal left ventricular relaxation in acute myocardial ischemia with a quadratic model. Med Eng Phys 2014;36(September (9)):1101-5 by Morimont et al.
Chung CS, Shmuylovich L, Kovács SJ
Med Eng Phys. 2015 Aug; 37(8)826. doi: 10.1016/j.medengphy.2015.05.002.

PMID:
    26050201
    [PubMed - indexed for MEDLINE]
Related citations


Diastolic function in heart failure.
Kovács SJ
Clin Med Insights Cardiol. 2015; 9(Suppl 1)49-55. doi: 10.4137/CMC.S18743.

PMID:
    25922587
    [PubMed]
Related citations


Fractionating E-wave deceleration time into its stiffness and relaxation components distinguishes pseudonormal from normal filling.
Mossahebi S, Zhu S, Kovács SJ
Circ Cardiovasc Imaging. 2015 Jan; 8(1)pii: e002177. doi: 10.1161/CIRCIMAGING.114.002177.

PMID:
    25596141
    [PubMed - indexed for MEDLINE]
Related citations


The effects of CYP3A4 induction and inhibition on the pharmacokinetics of alisporivir in humans.
Barve A, Kovacs SJ, Ke J, Crabbe R, Grosgurin P, Menetrey A, Nicolas-Métral V, Dabovic K, Dole K, Zhang J, Praestgaard J, Sunkara G, Stein D
Clin Pharmacol Drug Dev. 2015 Jan; 4(1)25-32. doi: 10.1002/cpdd.114.

PMID:
    27128001
    [PubMed - indexed for MEDLINE]
Related citations


Quantification of global diastolic function by kinematic modeling-based analysis of transmitral flow via the parametrized diastolic filling formalism.
Mossahebi S, Zhu S, Chen H, Shmuylovich L, Ghosh E, Kovács SJ
J Vis Exp. 2014 Sep 1; (91)e51471. doi: 10.3791/51471.

PMID:
    25226101
    [PubMed - indexed for MEDLINE]
Related citations


E-wave generated intraventricular diastolic vortex to L-wave relation: model-based prediction with in vivo validation.
Ghosh E, Caruthers SD, Kovács SJ
J Appl Physiol (1985). 2014 Aug 1; 117(3)316-24. doi: 10.1152/japplphysiol.00215.2014.

PMID:
    24903922
    [PubMed - indexed for MEDLINE]
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