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Samir K. El-Mofty, DMD, PhD, MS

Professor, Oral and Maxillofacial Pathology
Associate Professor, Pathology & Immunology
Associate Professor, Otolaryngology - Head and Neck Surgery

Specialty Areas

Pathology
Head and Neck Pathology
Head and Neck Surgery

Board Certifications

Oral and Maxillofacial Pathology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Oral and maxillofacial pathology

  • Education
  • Publication & Research

Education

Education

DDS: Cairo University, Cairo, Egypt 1961
PhD, Pathology: Temple University, Philadelphia, PA 1976
MS, Oral Surgery: University of Pennsylvania, Philadelphia, PA 1966
DMD: Washington University School of Medicine, St. Louis, MO 1987

Publication & Research

Publication & Research

Malignant Transformation of a Desmoplastic Ameloblastoma to Squamous Cell Carcinoma: A Case Report.
Rais R, El-Mofty SK
Head Neck Pathol. 2018 Jul 4; doi: 10.1007/s12105-018-0946-y.

PMID:
    29974411
    [PubMed - as supplied by publisher]
Related citations


Salivary Duct Carcinoma and Invasive Ductal Carcinoma of the Breast: A Comparative Immunohistochemical Study.
Jalaly JB, Sanati S, Chernock RD, Dibe DG, El-Mofty SK
Head Neck Pathol. 2018 Jan 4; doi: 10.1007/s12105-017-0882-2.

PMID:
    29302899
    [PubMed - as supplied by publisher]
Related citations


Gnathodiaphyseal dysplasia: Severe atypical presentation with novel heterozygous mutation of the anoctamin gene (ANO5).
Otaify GA, Whyte MP, Gottesman GS, McAlister WH, Eric Gordon J, Hollander A, Andrews MV, El-Mofty SK, Chen WS, Veis DV, Stolina M, Woo AS, Katsonis P, Lichtarge O, Zhang F, Shinawi M
Bone. 2018 Feb; 107161-171. doi: 10.1016/j.bone.2017.11.012.

PMID:
    29175271
    [PubMed - in process]
Related citations


p16 expression in follicular dendritic cell sarcoma: a potential mimicker of human papillomavirus-related oropharyngeal squamous cell carcinoma.
Zhang L, Yang C, Lewis JS Jr, El-Mofty SK, Chernock RD
Hum Pathol. 2017 Aug; 6640-47. doi: 10.1016/j.humpath.2017.05.019.

PMID:
    28554574
    [PubMed - indexed for MEDLINE]
Related citations


SMARCB1 (INI-1)-deficient Sinonasal Carcinoma: A Series of 39 Cases Expanding the Morphologic and Clinicopathologic Spectrum of a Recently Described Entity.
Agaimy A, Hartmann A, Antonescu CR, Chiosea SI, El-Mofty SK, Geddert H, Iro H, Lewis JS Jr, Märkl B, Mills SE, Riener MO, Robertson T, Sandison A, Semrau S, Simpson RH, Stelow E, Westra WH, Bishop JA
Am J Surg Pathol. 2017 Apr; 41(4)458-471. doi: 10.1097/PAS.0000000000000797.

PMID:
    28291122
    [PubMed - indexed for MEDLINE]
Related citations


Nonkeratinizing Squamous Cell Carcinoma In Situ of the Upper Aerodigestive Tract: An HPV-Related Entity.
Zhang L, Lewis JS Jr, El-Mofty SK, Gandhi M, Chernock RD
Head Neck Pathol. 2017 Jun; 11(2)152-161. doi: 10.1007/s12105-016-0749-y.

PMID:
    27492445
    [PubMed - indexed for MEDLINE]
Related citations


Expression of CDX2 and Thyroid Transcription Factor-1 in Oropharyngeal Undifferentiated Carcinomas: A Potential Diagnostic Pitfall.
Chernock RD, Bibbey S, El-Mofty SK, Carpenter DH, Lewis JS Jr
Appl Immunohistochem Mol Morphol. 2018 Apr; 26(4)268-273. doi: 10.1097/PAI.0000000000000414.

PMID:
    27389559
    [PubMed - in process]
Related citations


Histologic Typing in Oropharyngeal Squamous Cell Carcinoma: A 4-Year Prospective Practice Study With p16 and High-Risk HPV mRNA Testing Correlation.
Gondim DD, Haynes W, Wang X, Chernock RD, El-Mofty SK, Lewis JS Jr
Am J Surg Pathol. 2016 Aug; 40(8)1117-24. doi: 10.1097/PAS.0000000000000650.

PMID:
    27035614
    [PubMed - indexed for MEDLINE]
Related citations


Diagnostic Discrepancies in Mandatory Slide Review of Extradepartmental Head and Neck Cases: Experience at a Large Academic Center.
Mehrad M, Chernock RD, El-Mofty SK, Lewis JS Jr
Arch Pathol Lab Med. 2015 Dec; 139(12)1539-45. doi: 10.5858/arpa.2014-0628-OA.

PMID:
    26619026
    [PubMed - indexed for MEDLINE]
Related citations


Human papillomavirus-related head and neck squamous cell carcinoma variants.
El-Mofty SK
Semin Diagn Pathol. 2015 Jan; 32(1)23-31. doi: 10.1053/j.semdp.2015.02.022.

PMID:
    25804342
    [PubMed - indexed for MEDLINE]
Related citations


Low-grade papillary schneiderian carcinoma, a unique and deceptively bland malignant neoplasm: report of a case.
Lewis JS Jr, Chernock RD, Haynes W, El-Mofty SK
Am J Surg Pathol. 2015 May; 39(5)714-21. doi: 10.1097/PAS.0000000000000390.

PMID:
    25634744
    [PubMed - indexed for MEDLINE]
Related citations


Epidermal Growth Factor Receptor Expression in Spindle Cell Carcinomas of the Head and Neck.
Watson RF, Chernock RD, Zhang KH, Michel LS, Adkins DR, El-Mofty SK, Lewis JS Jr
Head Neck Pathol. 2015 Sep; 9(3)360-8. doi: 10.1007/s12105-014-0604-y.

PMID:
    25563452
    [PubMed - indexed for MEDLINE]
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Fibro-osseous lesions of the craniofacial skeleton: an update.
El-Mofty SK
Head Neck Pathol. 2014 Dec; 8(4)432-44. doi: 10.1007/s12105-014-0590-0.

PMID:
    25409854
    [PubMed - indexed for MEDLINE]
Related citations


Prevalence of a hobnail pattern in papillary, poorly differentiated, and anaplastic thyroid carcinoma: a possible manifestation of high-grade transformation.
Amacher AM, Goyal B, Lewis JS Jr, El-Mofty SK, Chernock RD
Am J Surg Pathol. 2015 Feb; 39(2)260-5. doi: 10.1097/PAS.0000000000000329.

PMID:
    25321328
    [PubMed - indexed for MEDLINE]
Related citations


Verrucous carcinoma with dysplasia or minimal invasion: a variant of verrucous carcinoma with extremely favorable prognosis.
Patel KR, Chernock RD, Sinha P, Müller S, El-Mofty SK, Lewis JS Jr
Head Neck Pathol. 2015 Mar; 9(1)65-73. doi: 10.1007/s12105-014-0551-7.

PMID:
    24947053
    [PubMed - indexed for MEDLINE]
Related citations


Histopathologic risk factors in oral and oropharyngeal squamous cell carcinoma variants: an update with special reference to HPV-related carcinomas.
El-Mofty SK
Med Oral Patol Oral Cir Bucal. 2014 Jul 1; 19(4)e377-85.

PMID:
    24880454
    [PubMed - indexed for MEDLINE]
Related citations


Keratinizing-type squamous cell carcinoma of the oropharynx: p16 overexpression is associated with positive high-risk HPV status and improved survival.
Cai C, Chernock RD, Pittman ME, El-Mofty SK, Thorstad WL, Lewis JS Jr
Am J Surg Pathol. 2014 Jun; 38(6)809-15. doi: 10.1097/PAS.0000000000000183.

PMID:
    24698966
    [PubMed - indexed for MEDLINE]
Related citations


Evaluation of a new grading system for laryngeal squamous intraepithelial lesions--a proposed unified classification.
Gale N, Blagus R, El-Mofty SK, Helliwell T, Prasad ML, Sandison A, Volavšek M, Wenig BM, Zidar N, Cardesa A
Histopathology. 2014 Oct; 65(4)456-64. doi: 10.1111/his.12427.

PMID:
    24689850
    [PubMed - indexed for MEDLINE]
Related citations


Tophaceous pseudogout of the temporomandibular joint: a series of 3 cases.
Abdelsayed RA, Said-Al-Naief N, Salguerio M, Holmes J, El-Mofty SK
Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Mar; 117(3)369-75. doi: 10.1016/j.oooo.2013.12.007.

PMID:
    24528794
    [PubMed - indexed for MEDLINE]
Related citations


Histologic and systemic prognosticators for local control and survival in margin-negative transoral laser microsurgery treated oral cavity squamous cell carcinoma.
Sinha P, Mehrad M, Chernock RD, Lewis JS Jr, El-Mofty SK, Wu N, Nussenbaum B, Haughey BH
Head Neck. 2015 Jan; 37(1)52-63. doi: 10.1002/hed.23553.

PMID:
    24430914
    [PubMed - indexed for MEDLINE]
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