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Ryan C. Fields, MD

Professor, Surgery
Division of General Surgery
Chief, Section of Surgical Oncology

Specialty Areas

Melanoma
Hepatobiliary Cancer
Sarcoma
Gastrointestinal Oncology
Liver Surgery
Pancreatic Cancer

Hospital Affiliations

Barnes-Jewish West County Hospital
Barnes-Jewish Hospital

Areas of Clinical Interest

Dr Fields specializes in surgical oncology, the surgical treatment of cancer including  tumors of the upper gastrointestinal tract, pancreatic cancer, liver tumors, primary liver tumor, metastatic liver tumor, gastric cancer, stomach cancer, GI stromal tumor, GIST, small bowel tumor,  neuroendocrine tumors, carcinoid tumors.  He has advanced training in surgical treatment of skin cancer, melanoma, Merkel cell carcinoma, basal cell, squamous cell cancer, sarcoma,  retroperitoneal sarcoma.  Also he treats patients with benign hepatobiliary disease, pancreatic conditions.  Dr. Fields also performs  isolated limb Infusion (ILI) and isolated limb perfusion (ILP) for advanced extremity melanoma and other skin/soft tissue malignancies.

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

Center for Advanced Medicine
Gastrointestinal Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 8
Office Phone: 314-286-1694
Fax: 314-222-6255

Barnes-Jewish West County Hospital 
Siteman Cancer Center
Medical Building Two

10 Barnes West Drive
Creve Coeur, MO 63141
Phone: 314-747-7222

Office Phone: 314-286-1694

Education

Education

Fellowship (Research): Surgery and Immunology, Washington University School of Medicine, St. Louis, MO 2006
Medical School : Duke University School of Medicine, Durham, NC, 2003
Residency: General Surgery, Barnes-Jewish Hospital, St. Louis MO 2008
Chief Resident (Administrative): General Surgery, Barnes-Jewish Hospital, St. Louis MO 2009
Fellowship: Surgical Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 2011

Publication & Research

Publication & Research

B cell-Derived IL35 Drives STAT3-Dependent CD8<sup>+</sup> T-cell Exclusion in Pancreatic Cancer.
Mirlekar B, Michaud D, Lee SJ, Kren NP, Harris C, Greene K, Goldman EC, Gupta GP, Fields RC, Hawkins WG, DeNardo DG, Rashid NU, Yeh JJ, McRee AJ, Vincent BG, Vignali DAA, Pylayeva-Gupta Y
Cancer Immunol Res. 2020 Feb 5; doi: 10.1158/2326-6066.CIR-19-0349.

PMID:
    32024640
    [PubMed - as supplied by publisher]
Related citations


NCCN Guidelines Insights: Uveal Melanoma, Version 1.2019.
Rao PK, Barker C, Coit DG, Joseph RW, Materin M, Rengan R, Sosman J, Thompson JA, Albertini MR, Boland G, Carson Iii WE, Contreras C, Daniels GA, DiMaio D, Durham A, Fields RC, Fleming MD, Galan A, Gastman B, Grossman K, Guild V, Johnson D, Karakousis G, Lange JR, ScM., Margolin K, Nath S, Olszanski AJ, Ott PA, Ross MI, Salama AK, Skitzki J, Swetter SM, Wuthrick E, McMillian NR, Engh A
J Natl Compr Canc Netw. 2020 Feb; 18(2)120-131. doi: 10.6004/jnccn.2020.0007.

PMID:
    32023525
    [PubMed - in process]
Related citations


Evaluating the ACS-NSQIP Risk Calculator in Primary GI Neuroendocrine Tumor: Results from the United States Neuroendocrine Tumor Study Group.
Armstrong EA, Beal EW, Lopez-Aguiar AG, Poultsides G, Cannon JG, Rocha F, Crown A, Barrett J, Ronnkleiv-Kelly S, Fields RC, Krasnick BA, Idrees K, Smith PM, Nathan H, Beems MV, Maithel SK, Schmidt CR, Pawlik TM, Dillhoff M
Am Surg. 2019 Dec 1; 85(12)1334-1340.

PMID:
    31908214
    [PubMed - indexed for MEDLINE]
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Survival benefit of lymphadenectomy for gallbladder cancer based on the therapeutic index: An analysis of the US extrahepatic biliary malignancy consortium.
Sahara K, Tsilimigras DI, Maithel SK, Abbott DE, Poultsides GA, Hatzaras I, Fields RC, Weiss M, Scoggins C, Isom CA, Idrees K, Shen P, Endo I, Pawlik TM, and the US Extrahepatic Biliary Malignancy Consortium.
J Surg Oncol. 2020 Mar; 121(3)503-510. doi: 10.1002/jso.25825.

PMID:
    31907941
    [PubMed - indexed for MEDLINE]
Related citations


Composite Length of Stay, An Outcome Measure of Postoperative and Readmission Length of Stays in Pancreatoduodenectomy.
Williams GA, Liu J, Chapman WC, Hawkins WG, Fields RC, Sanford DE, Doyle MB, Hammill CW, Khan AS, Strasberg SM
J Gastrointest Surg. 2019 Dec 16; doi: 10.1007/s11605-019-04475-8.

PMID:
    31845140
    [PubMed - as supplied by publisher]
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Impact of perioperative blood transfusion on survival in pancreatic neuroendocrine tumor patients: analysis from the US Neuroendocrine Study Group.
Marincola Smith P, Baechle J, Solórzano CC, Tan M, Lopez-Aguiar AG, Dillhoff M, Beal E, Poultsides G, Cannon JGD, Rocha FG, Crown A, Cho C, Beems M, Winslow ER, Rendell VR, Krasnick BA, Fields RC, Maithel SK, Bailey CE, Idrees K
HPB (Oxford). 2019 Dec 2; pii: S1365-182X(19)33183-1. doi: 10.1016/j.hpb.2019.10.2441.

PMID:
    31806388
    [PubMed - as supplied by publisher]
Related citations


Appendiceal Neuroendocrine Tumors: Does Colon Resection Improve Outcomes?
Crown A, Simianu VV, Kennecke H, Lopez-Aguiar AG, Dillhoff M, Beal EW, Poultsides GA, Makris E, Idrees K, Smith PM, Nathan H, Beems M, Abbott D, Barrett J, Fields RC, Davidson J, Maithel SK, Rocha FG
J Gastrointest Surg. 2019 Nov 20; doi: 10.1007/s11605-019-04431-6.

PMID:
    31749094
    [PubMed - as supplied by publisher]
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Assessment of Hepatic Arterial Infusion of Floxuridine in Combination With Systemic Gemcitabine and Oxaliplatin in Patients With Unresectable Intrahepatic Cholangiocarcinoma: A Phase 2 Clinical Trial.
Cercek A, Boerner T, Tan BR, Chou JF, Gönen M, Boucher TM, Hauser HF, Do RKG, Lowery MA, Harding JJ, Varghese AM, Reidy-Lagunes D, Saltz L, Schultz N, Kingham TP, D'Angelica MI, DeMatteo RP, Drebin JA, Allen PJ, Balachandran VP, Lim KH, Sanchez-Vega F, Vachharajani N, Majella Doyle MB, Fields RC, Hawkins WG, Strasberg SM, Chapman WC, Diaz LA Jr, Kemeny NE, Jarnagin WR
JAMA Oncol. 2019 Oct 31; doi: 10.1001/jamaoncol.2019.3718.

PMID:
    31670750
    [PubMed - as supplied by publisher]
Related citations


Conditional disease-free survival after curative-intent liver resection for neuroendocrine liver metastasis.
Sahara K, Merath K, Tsilimigras DI, Hyer JM, Guglielmi A, Aldrighetti L, Weiss M, Fields RC, Poultsides GA, Maithel SK, Endo I, Pawlik TM, Other Members Of The U S Neuroendocrine Tumor Study Group
J Surg Oncol. 2019 Dec; 120(7)1087-1095. doi: 10.1002/jso.25713.

PMID:
    31550406
    [PubMed - indexed for MEDLINE]
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Correction to: Neuroendocrine Liver Metastasis: Prognostic Implications of Primary Tumor Site on Patients Undergoing Curative Intent Liver Surgery.
Spolverato G, Bagante F, Aldrighetti L, Poultsides G, Bauer TW, Fields RC, Marques HP, Weiss M, Maithel SK, Pawlik TM
J Gastrointest Surg. 2020 Jan; 24(1)231. doi: 10.1007/s11605-019-04371-1.

PMID:
    31529199
    [PubMed]
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IRAK4 mediates colitis-induced tumorigenesis and chemoresistance in colorectal cancer.
Li Q, Chen Y, Zhang D, Grossman J, Li L, Khurana N, Jiang H, Grierson PM, Herndon J, DeNardo DG, Challen GA, Liu J, Ruzinova MB, Fields RC, Lim KH
JCI Insight. 2019 Oct 3; 4(19)pii: 130867. doi: 10.1172/jci.insight.130867.

PMID:
    31527315
    [PubMed - in process]
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Trends in the Use of Adjuvant Chemotherapy for High-Grade Truncal and Extremity Soft Tissue Sarcomas.
Squires MH, Ethun CG, Suarez-Kelly LP, Yu PY, Hughes TM, Shelby RD, Tran TB, Poultsides G, Charlson J, Gamblin TC, Tseng J, Roggin KK, Chouliaras K, Votanopoulos K, Krasnick BA, Fields RC, Pollock RE, Grignol V, Cardona K, Howard JH
J Surg Res. 2020 Jan; 245577-586. doi: 10.1016/j.jss.2019.08.002.

PMID:
    31494391
    [PubMed - indexed for MEDLINE]
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Role of radiation therapy for retroperitoneal sarcomas: An eight-institution study from the US Sarcoma Collaborative.
Chouliaras K, Senehi R, Ethun CG, Poultsides G, Grignol V, Clarke CN, Roggin KK, Fields RC, Schwartz PB, Ronnekleiv-Kelly SM, D'Agostino R Jr, Johnson EN, Levine EA, Cardona K, Votanopoulos KI
J Surg Oncol. 2019 Dec; 120(7)1227-1234. doi: 10.1002/jso.25694.

PMID:
    31486096
    [PubMed - indexed for MEDLINE]
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T Cell- and Monocyte-Specific RNA-Sequencing Analysis in Septic and Nonseptic Critically Ill Patients and in Patients with Cancer.
Washburn ML, Wang Z, Walton AH, Goedegebuure SP, Figueroa DJ, Van Horn S, Grossman J, Remlinger K, Madsen H, Brown J, Srinivasan R, Wolf AI, Berger SB, Yi VN, Hawkins WG, Fields RC, Hotchkiss RS
J Immunol. 2019 Oct 1; 203(7)1897-1908. doi: 10.4049/jimmunol.1900560.

PMID:
    31484735
    [PubMed - in process]
Related citations


Therapeutic index of lymphadenectomy among patients with pancreatic neuroendocrine tumors: A multi-institutional analysis.
Wu L, Sahara K, Tsilimigras DI, Maithel SK, Poultsides GA, Rocha FG, Weber SM, Fields RC, Idrees K, Cho CS, Shen F, Pawlik TM, and other members of the U.S. Neuroendocrine Tumor Study Group.
J Surg Oncol. 2019 Dec; 120(7)1080-1086. doi: 10.1002/jso.25689.

PMID:
    31468550
    [PubMed - indexed for MEDLINE]
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Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles.
Strand MS, Krasnick BA, Pan H, Zhang X, Bi Y, Brooks C, Wetzel C, Sankpal N, Fleming T, Goedegebuure SP, DeNardo DG, Gillanders WE, Hawkins WG, Wickline SA, Fields RC
Oncotarget. 2019 Jul 30; 10(46)4761-4775. doi: 10.18632/oncotarget.27109.

PMID:
    31413817
    [PubMed]
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Interaction of race and pathology for neuroendocrine tumors: Epidemiology, natural history, or racial disparity?
DePalo DK, Lee RM, Lopez-Aguiar AG, Gamboa AC, Rocha F, Poultsides G, Dillhoff M, Fields RC, Idrees K, Nathan H, Abbott D, Maithel SK, Russell MC, other members of the United States Neuroendocrine Tumor Study Group.
J Surg Oncol. 2019 Nov; 120(6)919-925. doi: 10.1002/jso.25662.

PMID:
    31385621
    [PubMed - indexed for MEDLINE]
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Lung Surveillance Strategy for High-Grade Soft Tissue Sarcomas: Chest X-Ray or CT Scan?
Gamboa AC, Ethun CG, Switchenko JM, Lipscomb J, Poultsides GA, Grignol V, Howard JH, Gamblin TC, Roggin KK, Votanopoulos K, Fields RC, Maithel SK, Delman KA, Cardona K
J Am Coll Surg. 2019 Nov; 229(5)449-457. doi: 10.1016/j.jamcollsurg.2019.07.010.

PMID:
    31377411
    [PubMed - in process]
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A 22-year experience with pancreatic resection for metastatic renal cell carcinoma.
Anderson B, Williams GA, Sanford DE, Lu J, Dageforde LA, Hammill CW, Fields RC, Hawkins WG, Strasberg SM, Doyle MB, Chapman WC, Khan AS
HPB (Oxford). 2019 Jul 23; pii: S1365-182X(19)30569-6. doi: 10.1016/j.hpb.2019.05.019.

PMID:
    31345661
    [PubMed - as supplied by publisher]
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Assessing the Role of Neoadjuvant Chemotherapy in Primary High-Risk Truncal/Extremity Soft Tissue Sarcomas: An Analysis of the Multi-institutional U.S. Sarcoma Collaborative.
Zaidi MY, Ethun CG, Tran TB, Poultsides G, Grignol VP, Howard JH, Bedi M, Mogal H, Tseng J, Roggin KK, Chouliaras K, Votanopoulos K, Krasnick B, Fields RC, Oskouei S, Reimer N, Monson D, Maithel SK, Cardona K
Ann Surg Oncol. 2019 Oct; 26(11)3542-3549. doi: 10.1245/s10434-019-07639-7.

PMID:
    31342400
    [PubMed - indexed for MEDLINE]
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