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Robert J. Hayashi, MD

Professor, Pediatrics
Director, Division of Pediatric Hematology and Oncology
Director, Bone Marrow Transplant Unit

Specialty Areas

Pediatric Hematology
Pediatric Oncology
Bone Marrow Transplant

Board Certifications

Pediatrics
Pediatric Hematology & Oncology

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Leukemia, blood disorders, cancer in children, bone marrow transplantation, post-transplant lymphoproliferative disease, allogeneic transplant, malignant and non-malignant diseases in children.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: 9th Floor, South
Office Phone: 314-454-6018
Fax: 314-454-2780

St. Louis Children's Specialty Care Center

13001 North Outer Forty
St. Louis, MO 63017

Suite: 2E
Office Phone: 314-454-6018
Fax: 314-454-2780

Education

Education

Fellowship: Pediatric Hematology & Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland 1992
Residency: Pediatrics, St. Louis Children's Hospital at Washington University School of Medicine, St. Louis, MO 1989
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1986
B.S.: Stanford University, Stanford, California 1982

Publication & Research

Publication & Research

Long-Term Follow-Up after Reduced-Intensity Conditioning and Stem Cell Transplantation for Childhood Nonmalignant Disorders.
Madden LM, Hayashi RJ, Chan KW, Pulsipher MA, Douglas D, Hale GA, Chaudhury S, Haut P, Kasow KA, Gilman A, Murray LM, Shenoy S
Biol Blood Marrow Transplant. 2016 May 6; pii: S1083-8791(16)30064-7. doi: 10.1016/j.bbmt.2016.04.025.

PMID:
    27164064
    [PubMed - as supplied by publisher]
Related citations


The genomic landscape of juvenile myelomonocytic leukemia.
Stieglitz E, Taylor-Weiner AN, Chang TY, Gelston LC, Wang YD, Mazor T, Esquivel E, Yu A, Seepo S, Olsen SR, Rosenberg M, Archambeault SL, Abusin G, Beckman K, Brown PA, Briones M, Carcamo B, Cooper T, Dahl GV, Emanuel PD, Fluchel MN, Goyal RK, Hayashi RJ, Hitzler J, Hugge C, Liu YL, Messinger YH, Mahoney DH Jr, Monteleone P, Nemecek ER, Roehrs PA, Schore RJ, Stine KC, Takemoto CM, Toretsky JA, Costello JF, Olshen AB, Stewart C, Li Y, Ma J, Gerbing RB, Alonzo TA, Getz G, Gruber TA, Golub TR, Stegmaier K, Loh ML
Nat Genet. 2015 Nov; 47(11)1326-33. doi: 10.1038/ng.3400.

PMID:
    26457647
    [PubMed - indexed for MEDLINE]
Related citations


Successful matched sibling donor marrow transplantation following reduced intensity conditioning in children with hemoglobinopathies.
King AA, Kamani N, Bunin N, Sahdev I, Brochstein J, Hayashi RJ, Grimley M, Abraham A, Dioguardi J, Chan KW, Douglas D, Adams R, Andreansky M, Anderson E, Gilman A, Chaudhury S, Yu L, Dalal J, Hale G, Cuvelier G, Jain A, Krajewski J, Gillio A, Kasow KA, Delgado D, Hanson E, Murray L, Shenoy S
Am J Hematol. 2015 Dec; 90(12)1093-8. doi: 10.1002/ajh.24183.

PMID:
    26348869
    [PubMed - in process]
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Transplant Outcomes for Children with T Cell Acute Lymphoblastic Leukemia in Second Remission: A Report from the Center for International Blood and Marrow Transplant Research.
Burke MJ, Verneris MR, Le Rademacher J, He W, Abdel-Azim H, Abraham AA, Auletta JJ, Ayas M, Brown VI, Cairo MS, Chan KW, Diaz Perez MA, Dvorak CC, Egeler RM, Eldjerou L, Frangoul H, Guilcher GM, Hayashi RJ, Ibrahim A, Kasow KA, Leung WH, Olsson RF, Pulsipher MA, Shah N, Shah NN, Thiel E, Talano JA, Kitko CL
Biol Blood Marrow Transplant. 2015 Dec; 21(12)2154-9. doi: 10.1016/j.bbmt.2015.08.023.

PMID:
    26327632
    [PubMed - in process]
Related citations


A prognostic model predicting autologous transplantation outcomes in children, adolescents and young adults with Hodgkin lymphoma.
Satwani P, Ahn KW, Carreras J, Abdel-Azim H, Cairo MS, Cashen A, Chen AI, Cohen JB, Costa LJ, Dandoy C, Fenske TS, Freytes CO, Ganguly S, Gale RP, Ghosh N, Hertzberg MS, Hayashi RJ, Kamble RT, Kanate AS, Keating A, Kharfan-Dabaja MA, Lazarus HM, Marks DI, Nishihori T, Olsson RF, Prestidge TD, Rolon JM, Savani BN, Vose JM, Wood WA, Inwards DJ, Bachanova V, Smith SM, Maloney DG, Sureda A, Hamadani M
Bone Marrow Transplant. 2015 Nov; 50(11)1416-23. doi: 10.1038/bmt.2015.177.

PMID:
    26237164
    [PubMed - in process]
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Tacrolimus versus Cyclosporine after Hematopoietic Cell Transplantation for Acquired Aplastic Anemia.
Inamoto Y, Flowers ME, Wang T, Urbano-Ispizua A, Hemmer MT, Cutler CS, Couriel DR, Alousi AM, Antin JH, Gale RP, Gupta V, Hamilton BK, Kharfan-Dabaja MA, Marks DI, Ringdén OT, Socié G, Solh MM, Akpek G, Cairo MS, Chao NJ, Hayashi RJ, Nishihori T, Reshef R, Saad A, Shah A, Teshima T, Tallman MS, Wirk B, Spellman SR, Arora M, Martin PJ
Biol Blood Marrow Transplant. 2015 Oct; 21(10)1776-82. doi: 10.1016/j.bbmt.2015.05.023.

PMID:
    26033280
    [PubMed - in process]
Related citations


The Impact of Graft-versus-Host Disease on the Relapse Rate in Patients with Lymphoma Depends on the Histological Subtype and the Intensity of the Conditioning Regimen.
Urbano-Ispizua A, Pavletic SZ, Flowers ME, Klein JP, Zhang MJ, Carreras J, Montoto S, Perales MA, Aljurf MD, Akpek G, Bredeson CN, Costa LJ, Dandoy C, Freytes CO, Fung HC, Gale RP, Gibson J, Hamadani M, Hayashi RJ, Inamoto Y, Inwards DJ, Lazarus HM, Maloney DG, Martino R, Munker R, Nishihori T, Olsson RF, Rizzieri DA, Reshef R, Saad A, Savani BN, Schouten HC, Smith SM, Socié G, Wirk B, Yu LC, Saber W
Biol Blood Marrow Transplant. 2015 Oct; 21(10)1746-53. doi: 10.1016/j.bbmt.2015.05.010.

PMID:
    25981509
    [PubMed - in process]
Related citations


Neurocognitive outcomes and school performance in solid tumor cancer survivors lacking therapy to the central nervous system.
Mohrmann C, Henry J, Hauff M, Hayashi RJ
J Pers Med. 2015 Apr 10; 5(2)83-90. doi: 10.3390/jpm5020083.

PMID:
    25867598
    [PubMed]
Related citations


Secondary solid cancer screening following hematopoietic cell transplantation.
Inamoto Y, Shah NN, Savani BN, Shaw BE, Abraham AA, Ahmed IA, Akpek G, Atsuta Y, Baker KS, Basak GW, Bitan M, DeFilipp Z, Gregory TK, Greinix HT, Hamadani M, Hamilton BK, Hayashi RJ, Jacobsohn DA, Kamble RT, Kasow KA, Khera N, Lazarus HM, Malone AK, Lupo-Stanghellini MT, Margossian SP, Muffly LS, Norkin M, Ramanathan M, Salooja N, Schoemans H, Wingard JR, Wirk B, Wood WA, Yong A, Duncan CN, Flowers ME, Majhail NS
Bone Marrow Transplant. 2015 Aug; 50(8)1013-23. doi: 10.1038/bmt.2015.63.

PMID:
    25822223
    [PubMed - indexed for MEDLINE]
Related citations


Alemtuzumab based reduced intensity transplantation for pediatric severe aplastic anemia.
Ngwube A, Hayashi RJ, Murray L, Loechelt B, Dalal J, Jaroscak J, Shenoy S
Pediatr Blood Cancer. 2015 Jul; 62(7)1270-6. doi: 10.1002/pbc.25458.

PMID:
    25755151
    [PubMed - indexed for MEDLINE]
Related citations


Increasing incidence of chronic graft-versus-host disease in allogeneic transplantation: a report from the Center for International Blood and Marrow Transplant Research.
Arai S, Arora M, Wang T, Spellman SR, He W, Couriel DR, Urbano-Ispizua A, Cutler CS, Bacigalupo AA, Battiwalla M, Flowers ME, Juckett MB, Lee SJ, Loren AW, Klumpp TR, Prockup SE, Ringdén OT, Savani BN, Socié G, Schultz KR, Spitzer T, Teshima T, Bredeson CN, Jacobsohn DA, Hayashi RJ, Drobyski WR, Frangoul HA, Akpek G, Ho VT, Lewis VA, Gale RP, Koreth J, Chao NJ, Aljurf MD, Cooper BW, Laughlin MJ, Hsu JW, Hematti P, Verdonck LF, Solh MM, Norkin M, Reddy V, Martino R, Gadalla S, Goldberg JD, McCarthy PL, Pérez-Simón JA, Khera N, Lewis ID, Atsuta Y, Olsson RF, Saber W, Waller EK, Blaise D, Pidala JA, Martin PJ, Satwani P, Bornhäuser M, Inamoto Y, Weisdorf DJ, Horowitz MM, Pavletic SZ, Graft-vs-Host Disease Working Committee of the CIBMTR
Biol Blood Marrow Transplant. 2015 Feb; 21(2)266-74. doi: 10.1016/j.bbmt.2014.10.021.

PMID:
    25445023
    [PubMed - indexed for MEDLINE]
Related citations


Late toxicity of a novel allogeneic stem cell transplant using single fraction total body irradiation for hematologic malignancies in children.
Madden LM, Ngwube AI, Shenoy S, Druley TE, Hayashi RJ
J Pediatr Hematol Oncol. 2015 Mar; 37(2)e94-e101. doi: 10.1097/MPH.0000000000000272.

PMID:
    25333837
    [PubMed - indexed for MEDLINE]
Related citations


Long-term survival and late effects among one-year survivors of second allogeneic hematopoietic cell transplantation for relapsed acute leukemia and myelodysplastic syndromes.
Duncan CN, Majhail NS, Brazauskas R, Wang Z, Cahn JY, Frangoul HA, Hayashi RJ, Hsu JW, Kamble RT, Kasow KA, Khera N, Lazarus HM, Loren AW, Marks DI, Maziarz RT, Mehta P, Myers KC, Norkin M, Pidala JA, Porter DL, Reddy V, Saber W, Savani BN, Schouten HC, Steinberg A, Wall DA, Warwick AB, Wood WA, Yu LC, Jacobsohn DA, Sorror ML
Biol Blood Marrow Transplant. 2015 Jan; 21(1)151-8. doi: 10.1016/j.bbmt.2014.10.006.

PMID:
    25316109
    [PubMed - indexed for MEDLINE]
Related citations


Second solid cancers after allogeneic hematopoietic cell transplantation using reduced-intensity conditioning.
Ringdén O, Brazauskas R, Wang Z, Ahmed I, Atsuta Y, Buchbinder D, Burns LJ, Cahn JY, Duncan C, Hale GA, Halter J, Hayashi RJ, Hsu JW, Jacobsohn DA, Kamble RT, Kamani NR, Kasow KA, Khera N, Lazarus HM, Loren AW, Marks DI, Myers KC, Ramanathan M, Saber W, Savani BN, Schouten HC, Socie G, Sorror ML, Steinberg A, Popat U, Wingard JR, Mattsson J, Majhail NS
Biol Blood Marrow Transplant. 2014 Nov; 20(11)1777-84. doi: 10.1016/j.bbmt.2014.07.009.

PMID:
    25042734
    [PubMed - indexed for MEDLINE]
Related citations


Differential effects of radiotherapy on growth and endocrine function among acute leukemia survivors: a childhood cancer survivor study report.
Chow EJ, Liu W, Srivastava K, Leisenring WM, Hayashi RJ, Sklar CA, Stovall M, Robison LL, Baker KS
Pediatr Blood Cancer. 2013 Jan; 60(1)110-5. doi: 10.1002/pbc.24198.

PMID:
    22628201
    [PubMed - indexed for MEDLINE]
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Late onset hearing loss: a significant complication of cancer survivors treated with Cisplatin containing chemotherapy regimens.
Kolinsky DC, Hayashi SS, Karzon R, Mao J, Hayashi RJ
J Pediatr Hematol Oncol. 2010 Mar; 32(2)119-23. doi: 10.1097/MPH.0b013e3181cb8593.

PMID:
    20098336
    [PubMed - indexed for MEDLINE]
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Hearing loss in pediatric oncology patients receiving carboplatin-containing regimens.
Dean JB, Hayashi SS, Albert CM, King AA, Karzon R, Hayashi RJ
J Pediatr Hematol Oncol. 2008 Feb; 30(2)130-4. doi: 10.1097/MPH.0b013e31815d1d83.

PMID:
    18376265
    [PubMed - indexed for MEDLINE]
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Cutaneous effects of thiotepa in pediatric patients receiving high-dose chemotherapy with autologous stem cell transplantation.
Rosman IS, Lloyd BM, Hayashi RJ, Bayliss SJ
J Am Acad Dermatol. 2008 Apr; 58(4)575-8. doi: 10.1016/j.jaad.2007.12.037.

PMID:
    18249465
    [PubMed - indexed for MEDLINE]
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Safety and efficacy of prolonged cytomegalovirus prophylaxis with intravenous ganciclovir in pediatric and young adult lung transplant recipients.
Spivey JF, Singleton D, Sweet S, Storch GA, Hayashi RJ, Huddleston CB, Danziger-Isakov LA
Pediatr Transplant. 2007 May; 11(3)312-8.

PMID:
    17430489
    [PubMed - indexed for MEDLINE]
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Requirement of high-affinity IL-2-IL-2R interaction for T cell anergy induction.
Hayashi RJ, Kanagawa O
Int Immunol. 2006 May; 18(5)645-51.

PMID:
    16574670
    [PubMed - indexed for MEDLINE]
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