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Robert E. Schmidt, MD, PhD

Professor, Pathology & Immunology
Director, Division of Neuropathology
Director, Research and Clinical Electron Microscopy Facility

Specialty Areas

Pathology
Neuropathology

Board Certifications

Anatomic Pathology
Neuropathology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Peripheral neuropathy, white matter diseases including multiple sclerosis, brain tumors, general neuropathology

  • Education
  • Publication & Research

Education

Education

Medical Degree: Washington University School of Medicine, St. Louis, MO 1976
Chief Resident, Neuropathology: Barnes-Jewish Hospital, St. Louis, MO 1980
Residency, Pathology: Barnes-Jewish Hospital, St. Louis, MO 1978
PhD, Medical Sciences: Washington University School of Medicine, St. Louis, MO 1976
Postdoctoral Fellow, Pharmacology: Washington University School of Medicine, St. Louis, MO 1976
Bachelor of Arts: Washington University, St. Louis, MO 1969

Publication & Research

Publication & Research

TREX1 is expressed by microglia in normal human brain and increases in regions affected by ischemia.
Kothari PH, Kolar GR, Jen JC, Hajj-Ali R, Bertram P, Schmidt RE, Atkinson JP
Brain Pathol. 2018 Jul 30; doi: 10.1111/bpa.12626.

PMID:
    30062819
    [PubMed - as supplied by publisher]
Related citations


Primary immunodeficiency disorder caused by phosphoinositide 3-kinase delta (PI3Kδ) deficiency.
Sogkas G, Fedchenko M, Dhingra A, Jablonka A, Schmidt RE, Atschekzei F
J Allergy Clin Immunol. 2018 Jul 21; pii: S0091-6749(18)31051-0. doi: 10.1016/j.jaci.2018.06.039.

PMID:
    30040974
    [PubMed - as supplied by publisher]
Related citations


Reciprocal relations between care-related emotional burden and sleep problems in healthcare professionals: a multicentre international cohort study.
Cheval B, Mongin D, Cullati S, Winz C, von Arx M, Schmidt RE, Agoritsas T, Chopard P, Courvoisier DS
Occup Environ Med. 2018 Jul 19; pii: oemed-2018-105096. doi: 10.1136/oemed-2018-105096.

PMID:
    30026283
    [PubMed - as supplied by publisher]
Related citations


Histopathological correlation of diffusion basis spectrum imaging metrics of a biopsy-proven inflammatory demyelinating brain lesion: A brief report.
Shirani A, Sun P, Schmidt RE, Trinkaus K, Naismith RT, Song SK, Cross AH
Mult Scler. 2018 Jul 1; 1352458518786072. doi: 10.1177/1352458518786072.

PMID:
    29992856
    [PubMed - as supplied by publisher]
Related citations


"We Won't Retire Without Skeletons in the Closet": Healthcare-Related Regrets Among Physicians and Nurses in German-Speaking Swiss Hospitals.
von Arx M, Cullati S, Schmidt RE, Richner S, Kraehenmann R, Cheval B, Agoritsas T, Chopard P, Burton-Jeangros C, Courvoisier DS
Qual Health Res. 2018 Sep; 28(11)1746-1758. doi: 10.1177/1049732318782434.

PMID:
    29945491
    [PubMed - in process]
Related citations


Patients With Arthralgia and Anti-Citrullinated Peptide Antibody Positivity on Hydroxychloroquine Therapy: An Update on 2 and 3 Years' Follow-up Data of a Pilot Study.
Merkesdal S, Kirchhoff T, Jablonka A, Schmidt RE, Köhler L
J Clin Rheumatol. 2018 Jun 15; doi: 10.1097/RHU.0000000000000816.

PMID:
    29912776
    [PubMed - as supplied by publisher]
Related citations


Tuberculosis Specific Interferon-Gamma Production in a Current Refugee Cohort in Western Europe.
Jablonka A, Dopfer C, Happle C, Sogkas G, Ernst D, Atschekzei F, Hirsch S, Schäll A, Jirmo A, Solbach P, Schmidt RE, Behrens GMN, Wetzke M
Int J Environ Res Public Health. 2018 Jun 14; 15(6)pii: E1263. doi: 10.3390/ijerph15061263.

PMID:
    29904012
    [PubMed - in process]
Related citations


Occurrence of the large ostracod, <i>Chlamydotheca unispinosa</i> (Baird, 1862), in temporary waters of Montserrat, Lesser Antilles.
Schmidt RE, Shoobs NF, McMullin ER
Zookeys. 2018; (748)89-95. doi: 10.3897/zookeys.748.22323.

PMID:
    29674916
    [PubMed]
Related citations


Amyloid-β Plaques in Clinical Alzheimer's Disease Brain Incorporate Stable Isotope Tracer <i>In Vivo</i> and Exhibit Nanoscale Heterogeneity.
Wildburger NC, Gyngard F, Guillermier C, Patterson BW, Elbert D, Mawuenyega KG, Schneider T, Green K, Roth R, Schmidt RE, Cairns NJ, Benzinger TLS, Steinhauser ML, Bateman RJ
Front Neurol. 2018; 9169. doi: 10.3389/fneur.2018.00169.

PMID:
    29623063
    [PubMed]
Related citations


Prevalence and Types of Anemia in a Large Refugee Cohort in Western Europe in 2015.
Jablonka A, Wetzke M, Sogkas G, Dopfer C, Schmidt RE, Behrens GMN, Happle C
J Immigr Minor Health. 2018 Mar 26; doi: 10.1007/s10903-018-0725-6.

PMID:
    29582203
    [PubMed - as supplied by publisher]
Related citations


Autoimmune Encephalitis With Multiple Autoantibodies: A Diagnostic and Therapeutic Challenge.
Kim AE, Kang P, Bucelli RC, Ferguson CJ, Schmidt RE, Varadhachary AS, Day GS
Neurologist. 2018 Mar; 23(2)55-59. doi: 10.1097/NRL.0000000000000171.

PMID:
    29494437
    [PubMed - in process]
Related citations


Prevalence and clinical challenges among adults with primary immunodeficiency and recombination-activating gene deficiency.
Lawless D, Geier CB, Farmer JR, Lango Allen H, Thwaites D, Atschekzei F, Brown M, Buchbinder D, Burns SO, Butte MJ, Csomos K, Deevi SVV, Egner W, Ehl S, Eibl MM, Fadugba O, Foldvari Z, Green DM, Henrickson SE, Holland SM, John T, Klemann C, Kuijpers TW, Moreira F, Piller A, Rayner-Matthews P, Romberg ND, Sargur R, Schmidt RE, Schröder C, Schuetz C, Sharapova SO, Smith KGC, Sogkas G, Speckmann C, Stirrups K, Thrasher AJ, Wolf HM, Notarangelo LD, Anwar R, Boyes J, Ujhazi B, NIHR BioResource–Rare Diseases Consortium., Thaventhiran J, Walter JE, Savic S
J Allergy Clin Immunol. 2018 Jun; 141(6)2303-2306. doi: 10.1016/j.jaci.2018.02.007.

PMID:
    29477728
    [PubMed - in process]
Related citations


C5aR activation in the absence of C5a: A new disease mechanism of autoimmune hemolytic anemia in mice.
Syed SN, Rau E, Ziegelmann M, Sogkas G, Brüne B, Schmidt RE
Eur J Immunol. 2018 Apr; 48(4)696-704. doi: 10.1002/eji.201747238.

PMID:
    29277896
    [PubMed - in process]
Related citations


A 60-Year-Old Woman with Multifocal Subcortical Infarcts.
Schwetye KE, Rodriguez D, Schmidt RE, Dahiya S
Brain Pathol. 2018 Jan; 28(1)131-132. doi: 10.1111/bpa.12579.

PMID:
    29265630
    [PubMed - in process]
Related citations


An 8-Year-Old Girl with A Supratentorial Mass.
Schwetye KE, Gauvain K, Rodriguez D, Cottrell C, Limbrick DD Jr, Schmidt RE, Dahiya S
Brain Pathol. 2018 Jan; 28(1)125-126. doi: 10.1111/bpa.12576.

PMID:
    29265627
    [PubMed - in process]
Related citations


Autoimmunity and primary immunodeficiency: two sides of the same coin?
Schmidt RE, Grimbacher B, Witte T
Nat Rev Rheumatol. 2017 Dec 19; 14(1)7-18. doi: 10.1038/nrrheum.2017.198.

PMID:
    29255211
    [PubMed - indexed for MEDLINE]
Related citations


Antibodies against MYC-Associated Zinc Finger Protein: An Independent Marker in Acute Coronary Syndrome?
Ernst D, Widera C, Baerlecken NT, Schlumberger W, Daehnrich C, Schmidt RE, Gabrysch K, Wallentin L, Witte T
Front Immunol. 2017; 81595. doi: 10.3389/fimmu.2017.01595.

PMID:
    29209328
    [PubMed]
Related citations


Autoantibodies binding to stathmin-4: new marker for polyneuropathy in primary Sjögren's syndrome.
Duda S, Witte T, Stangel M, Adams J, Schmidt RE, Baerlecken NT
Immunol Res. 2017 Dec; 65(6)1099-1102. doi: 10.1007/s12026-017-8970-7.

PMID:
    29138979
    [PubMed - in process]
Related citations


Evidence of inflammasome activation and formation of monocyte-derived ASC specks in HIV-1 positive patients.
Ahmad F, Mishra N, Ahrenstorf G, Franklin BS, Latz E, Schmidt RE, Bossaller L
AIDS. 2018 Jan 28; 32(3)299-307. doi: 10.1097/QAD.0000000000001693.

PMID:
    29135573
    [PubMed - in process]
Related citations


Norovirus outbreaks in german refugee camps in 2015.
Grote U, Schleenvoigt BT, Happle C, Dopfer C, Wetzke M, Ahrenstorf G, Holst H, Pletz MW, Schmidt RE, Behrens GM, Jablonka A
Z Gastroenterol. 2017 Oct; 55(10)997-1003. doi: 10.1055/s-0043-109701.

PMID:
    29020698
    [PubMed - in process]
Related citations

Areas of Research Interest

The pathogenesis of peripheral nerve disease with a particular focus on the autonomic nervous system in aging and diabetes. Pathologic examination of white matter disease with a special focus on multiple sclerosis.