FollowMyHealth Patient Portal

Robert E. Kleiger, MD

Professor, Medicine
Cardiovascular Division

Specialty Areas

Cardiology
Heart Disease
Cardiovascular Disease

Board Certifications

Cardiology
Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Not Accepting New Patients

Areas of Clinical Interest

Heart rate variability, congestive heart failure, coronary artery bypass, acute non-Q-wave myocardial infarction, supervising and interpreting diagnostic tests, such as echocardiograms, stress echocardiograms, treadmill stress test, holter, event and loop monitors.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Heart & Vascular Center

4921 Parkview Place
St. Louis, MO 63110

Suite: A
Floor: 8
Office Phone: 314-454-8097

Education

Education

Fellowship: Cardiology, Stanford University School of Medicine, Stanford, California 1969
Fellowship: Cardiology, Harvard School of Public Health, Peter Brigham Hospital, Cambridge, Massachusetts 1965
Residency: Barnes Hospital, St. Louis, Missouri 1963
Residency: Peter Bent Brigham Hospital, Boston, Massachusetts 1961
Medical Degree: Harvard Medical School, Cambridge, Massachusetts 1960
B.A.: Yale University, New Haven, Connecticut 1956

Publication & Research

Publication & Research

The postimplantation electrocardiogram predicts clinical response to cardiac resynchronization therapy.
Coverstone E, Sheehy J, Kleiger RE, Smith TW
Pacing Clin Electrophysiol. 2015 May; 38(5)572-80. doi: 10.1111/pace.12609.

PMID:
    25732143
    [PubMed - indexed for MEDLINE]
Related citations


Characteristics of the electrocardiogram in patients with continuous-flow left ventricular assist devices.
Martinez SC, Fansler D, Lau J, Novak EL, Joseph SM, Kleiger RE
Ann Noninvasive Electrocardiol. 2015 Jan; 20(1)62-8. doi: 10.1111/anec.12181.

PMID:
    25041228
    [PubMed - indexed for MEDLINE]
Related citations


Novel measures of heart rate variability predict cardiovascular mortality in older adults independent of traditional cardiovascular risk factors: the Cardiovascular Health Study (CHS).
Stein PK, Barzilay JI, Chaves PH, Mistretta SQ, Domitrovich PP, Gottdiener JS, Rich MW, Kleiger RE
J Cardiovasc Electrophysiol. 2008 Nov; 19(11)1169-74. doi: 10.1111/j.1540-8167.2008.01232.x.

PMID:
    18631274
    [PubMed - indexed for MEDLINE]
Related citations


Diastolic dysfunction and autonomic abnormalities in patients with systolic heart failure.
Stein PK, Tereshchenko L, Domitrovich PP, Kleiger RE, Perez A, Deedwania P
Eur J Heart Fail. 2007 Apr; 9(4)364-9.

PMID:
    17123863
    [PubMed - indexed for MEDLINE]
Related citations


Individualizing decisions for patients with prophylactic implantable cardiac defibrillators subject to device advisories: a commentary.
Bigger JT, Kleiger RE
Am J Cardiol. 2006 Nov 1; 98(9)1291-3.

PMID:
    17056349
    [PubMed - indexed for MEDLINE]
Related citations


Traditional and nonlinear heart rate variability are each independently associated with mortality after myocardial infarction.
Stein PK, Domitrovich PP, Huikuri HV, Kleiger RE, Cast Investigators.
J Cardiovasc Electrophysiol. 2005 Jan; 16(1)13-20.

PMID:
    15673380
    [PubMed - indexed for MEDLINE]
Related citations


Heart rate variability: measurement and clinical utility.
Kleiger RE, Stein PK, Bigger JT Jr
Ann Noninvasive Electrocardiol. 2005 Jan; 10(1)88-101.

PMID:
    15649244
    [PubMed - indexed for MEDLINE]
Related citations


Including patients with diabetes mellitus or coronary artery bypass grafting decreases the association between heart rate variability and mortality after myocardial infarction.
Stein PK, Domitrovich PP, Kleiger RE, CAST Investigators.
Am Heart J. 2004 Feb; 147(2)309-16.

PMID:
    14760330
    [PubMed - indexed for MEDLINE]
Related citations


Relation between pet ownership and heart rate variability in patients with healed myocardial infarcts.
Friedmann E, Thomas SA, Stein PK, Kleiger RE
Am J Cardiol. 2003 Mar 15; 91(6)718-21.

PMID:
    12633806
    [PubMed - indexed for MEDLINE]
Related citations


Early invasive versus ischaemia-guided strategies in the management of non-Q wave myocardial infarction patients with and without prior myocardial infarction; results of Veterans Affairs Non-Q Wave Infarction Strategies in Hospital (VANQWISH) trial.
Heggunje PS, Wade MJ, O'Rourke RA, Kleiger RE, Deedwania PC, Lavori PW, Boden WE, VANQWISH trial investigators.
Eur Heart J. 2000 Dec; 21(24)2014-25.

PMID:
    11102252
    [PubMed - indexed for MEDLINE]
Related citations


Severe depression is associated with markedly reduced heart rate variability in patients with stable coronary heart disease.
Stein PK, Carney RM, Freedland KE, Skala JA, Jaffe AS, Kleiger RE, Rottman JN
J Psychosom Res. 2000 Apr-May; 48(4-5)493-500.

PMID:
    10880671
    [PubMed - indexed for MEDLINE]
Related citations


Clinical and demographic determinants of heart rate variability in patients post myocardial infarction: insights from the cardiac arrhythmia suppression trial (CAST).
Stein PK, Domitrovich PP, Kleiger RE, Schechtman KB, Rottman JN
Clin Cardiol. 2000 Mar; 23(3)187-94.

PMID:
    10761807
    [PubMed - indexed for MEDLINE]
Related citations


Morphology of right ventricular paced beats in posterior myocardial infarction.
Thanigaraj S, Kleiger RE
South Med J. 2000 Mar; 93(3)323-6.

PMID:
    10728525
    [PubMed - indexed for MEDLINE]
Related citations


Assessment of ultra low frequency band power of heart rate variability: validation of alternative methods.
Bilge AR, Stein PK, Domitrovich PP, Gérard PL, Rottman JN, Kleiger RE, Kulbertus HE, Piérard LA
Int J Cardiol. 1999 Sep 30; 71(1)1-6.

PMID:
    10522558
    [PubMed - indexed for MEDLINE]
Related citations


Effect of exercise training on heart rate variability in healthy older adults.
Stein PK, Ehsani AA, Domitrovich PP, Kleiger RE, Rottman JN
Am Heart J. 1999 Sep; 138(3 Pt 1)567-76.

PMID:
    10467210
    [PubMed - indexed for MEDLINE]
Related citations


Comparison based on age of baseline electrocardiographic abnormalities in non-Q-wave myocardial infarction. VANQWISH Trial Research Investigators. Veterans Affairs Non-Q-Wave Infarction Strategies In-Hospital.
Stratmann HG, Kleiger RE, Ferry DR, Zoble RG, Chow BK, Lavori PW, Boden WE
J Am Geriatr Soc. 1999 Jul; 47(7)870-2.

PMID:
    10404934
    [PubMed - indexed for MEDLINE]
Related citations


Changes in 24-hour heart rate variability during normal pregnancy.
Stein PK, Hagley MT, Cole PL, Domitrovich PP, Kleiger RE, Rottman JN
Am J Obstet Gynecol. 1999 Apr; 180(4)978-85.

PMID:
    10203667
    [PubMed - indexed for MEDLINE]
Related citations


Mechanisms of death in the CABG Patch trial: a randomized trial of implantable cardiac defibrillator prophylaxis in patients at high risk of death after coronary artery bypass graft surgery.
Bigger JT Jr, Whang W, Rottman JN, Kleiger RE, Gottlieb CD, Namerow PB, Steinman RC, Estes NA 3rd
Circulation. 1999 Mar 23; 99(11)1416-21.

PMID:
    10086963
    [PubMed - indexed for MEDLINE]
Related citations


Insights from the study of heart rate variability.
Stein PK, Kleiger RE
Annu Rev Med. 1999; 50249-61.

PMID:
    10073276
    [PubMed - indexed for MEDLINE]
Related citations


RR interval dynamics before atrial fibrillation in patients after coronary artery bypass graft surgery.
Hogue CW Jr, Domitrovich PP, Stein PK, Despotis GD, Re L, Schuessler RB, Kleiger RE, Rottman JN
Circulation. 1998 Aug 4; 98(5)429-34.

PMID:
    9714093
    [PubMed - indexed for MEDLINE]
Related citations