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Robert C. McKinstry III, MD, PhD

Professor, Radiology
Division of Diagnostic Radiology
Pediatric Radiology and Neuroradiology Sections
Chief, Pediatric Radiology
Professor, Pediatrics

Specialty Areas

Pediatric Neuroradiology
Neuroradiology
Neuro Oncology
Radiology
Pediatric Radiology

Board Certifications

Radiology
Neuroradiology

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Magnetic resonance imaging, MRI, MR imaging of brain development, diffusion tensor imaging, perfusion MR imaging and functional MR imaging, functional neuroimaging with magnetic resonance

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish Hospital
Mallinckrodt Institute of Radiology

510 South Kingshighway Boulevard
St. Louis, MO 63110

Office Phone: 314-362-5949
Fax: 314-362-4886

Education

Education

Fellowship: Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri 1999
Residency: Mallinckrodt Institute of Radiology and Barnes-Jewish Hospital, St. Louis, Missouri 1997
Medical Degree: Harvard-MIT Division of Health Sciences & Technology, Harvard Medical School, Boston, Massachusetts 1992
Ph.D.: Radiological Sciences, Massachusetts Institute of Technology, Boston, Massachusetts 1991
B.S.: Boston University, Boston, Massachusetts 1984

Publication & Research

Publication & Research

Changes of White Matter Diffusion Anisotropy in Response to a 6-Week iPad Application-Based Occupational Therapy Intervention in Children with Surgically Treated Hydrocephalus: A Pilot Study.
Yuan W, Harpster K, Jones BV, Shimony JS, McKinstry RC, Weckherlin N, Powell SS, Barnard H, Engsberg J, Kadis DS, Dodd J, Altaye M, Limbrick DD, Holland SK, Simpson SM, Bidwell S, Mangano FT
Neuropediatrics. 2016 Oct; 47(5)336-40. doi: 10.1055/s-0036-1584938.

PMID:
    27438376
    [PubMed - in process]
Related citations


Anxious/depressed symptoms are related to microstructural maturation of white matter in typically developing youths.
Albaugh MD, Ducharme S, Karama S, Watts R, Lewis JD, Orr C, Nguyen TV, Mckinstry RC, Botteron KN, Evans AC, Hudziak JJ, Brain Development Cooperative Group
Dev Psychopathol. 2016 Jun 14; 1-8.

PMID:
    27297294
    [PubMed - as supplied by publisher]
Related citations


High-Dose Erythropoietin and Hypothermia for Hypoxic-Ischemic Encephalopathy: A Phase II Trial.
Wu YW, Mathur AM, Chang T, McKinstry RC, Mulkey SB, Mayock DE, Van Meurs KP, Rogers EE, Gonzalez FF, Comstock BA, Juul SE, Msall ME, Bonifacio SL, Glass HC, Massaro AN, Dong L, Tan KW, Heagerty PJ, Ballard RA
Pediatrics. 2016 Jun; 137(6)pii: e20160191. doi: 10.1542/peds.2016-0191.

PMID:
    27244862
    [PubMed - in process]
Related citations


Diffusion tensor imaging study of pediatric patients with congenital hydrocephalus: 1-year postsurgical outcomes.
Mangano FT, Altaye M, McKinstry RC, Shimony JS, Powell SK, Phillips JM, Barnard H, Limbrick DD Jr, Holland SK, Jones BV, Dodd J, Simpson S, Mercer D, Rajagopal A, Bidwell S, Yuan W
J Neurosurg Pediatr. 2016 Sep; 18(3)306-19. doi: 10.3171/2016.2.PEDS15628.

PMID:
    27203134
    [PubMed - in process]
Related citations


Development of cortical shape in the human brain from 6 to 24months of age via a novel measure of shape complexity.
Kim SH, Lyu I, Fonov VS, Vachet C, Hazlett HC, Smith RG, Piven J, Dager SR, Mckinstry RC, Pruett JR Jr, Evans AC, Collins DL, Botteron KN, Schultz RT, Gerig G, Styner MA, IBIS Network
Neuroimage. 2016 Jul 15; 135163-76. doi: 10.1016/j.neuroimage.2016.04.053.

PMID:
    27150231
    [PubMed - in process]
Related citations


Brain atrophy in paediatric sickle cell anaemia: findings from the silent infarct transfusion (SIT) trial.
Kawadler JM, Clark CA, McKinstry RC, Kirkham FJ
Br J Haematol. 2016 Apr 7; doi: 10.1111/bjh.14039.

PMID:
    27061199
    [PubMed - as supplied by publisher]
Related citations


De novo development of gliomas in a child with neurofibromatosis type 1, fragile X and previously normal brain magnetic resonance imaging.
Zafar R, Hsiao EY, Botteron KN, McKinstry RC, Gutmann DH
Radiol Case Rep. 2016 Mar; 11(1)33-5. doi: 10.1016/j.radcr.2015.12.008.

PMID:
    26973730
    [PubMed]
Related citations


Splenium development and early spoken language in human infants.
Swanson MR, Wolff JJ, Elison JT, Gu H, Hazlett HC, Botteron K, Styner M, Paterson S, Gerig G, Constantino J, Dager S, Estes A, Vachet C, Piven J, IBIS Network
Dev Sci. 2015 Oct 21; doi: 10.1111/desc.12360.

PMID:
    26490257
    [PubMed - as supplied by publisher]
Related citations


Trajectories of cortical thickness maturation in normal brain development--The importance of quality control procedures.
Ducharme S, Albaugh MD, Nguyen TV, Hudziak JJ, Mateos-Pérez JM, Labbe A, Evans AC, Karama S, Brain Development Cooperative Group
Neuroimage. 2016 Jan 15; 125267-79. doi: 10.1016/j.neuroimage.2015.10.010.

PMID:
    26463175
    [PubMed - in process]
Related citations


CT Dose Optimization in Pediatric Radiology: A Multiyear Effort to Preserve the Benefits of Imaging While Reducing the Risks.
Greenwood TJ, Lopez-Costa RI, Rhoades PD, Ramírez-Giraldo JC, Starr M, Street M, Duncan J, McKinstry RC
Radiographics. 2015 Sep-Oct; 35(5)1539-54. doi: 10.1148/rg.2015140267.

PMID:
    26267677
    [PubMed - indexed for MEDLINE]
Related citations


Abnormal structural connectivity in the brain networks of children with hydrocephalus.
Yuan W, Holland SK, Shimony JS, Altaye M, Mangano FT, Limbrick DD, Jones BV, Nash T, Rajagopal A, Simpson S, Ragan D, McKinstry RC
Neuroimage Clin. 2015; 8483-92. doi: 10.1016/j.nicl.2015.04.015.

PMID:
    26106573
    [PubMed - indexed for MEDLINE]
Related citations


The diffusion tensor imaging (DTI) component of the NIH MRI study of normal brain development (PedsDTI).
Walker L, Chang LC, Nayak A, Irfanoglu MO, Botteron KN, McCracken J, McKinstry RC, Rivkin MJ, Wang DJ, Rumsey J, Pierpaoli C, Brain Development Cooperative Group
Neuroimage. 2016 Jan 1; 124(Pt B)1125-30. doi: 10.1016/j.neuroimage.2015.05.083.

PMID:
    26048622
    [PubMed - indexed for MEDLINE]
Related citations


Periventricular hyperintensity in children with hydrocephalus.
Akbari SH, Limbrick DD Jr, McKinstry RC, Altaye M, Ragan DK, Yuan W, Mangano FT, Holland SK, Shimony JS
Pediatr Radiol. 2015 Jul; 45(8)1189-97. doi: 10.1007/s00247-015-3298-8.

PMID:
    25779827
    [PubMed - indexed for MEDLINE]
Related citations


Evaluation of the use of automatic exposure control and automatic tube potential selection in low-dose cerebrospinal fluid shunt head CT.
Wallace AN, Vyhmeister R, Bagade S, Chatterjee A, Hicks B, Ramirez-Giraldo JC, McKinstry RC
Neuroradiology. 2015 Jun; 57(6)639-44. doi: 10.1007/s00234-015-1508-6.

PMID:
    25779098
    [PubMed - indexed for MEDLINE]
Related citations


The accuracy of linear indices of ventricular volume in pediatric hydrocephalus: technical note.
Ragan DK, Cerqua J, Nash T, McKinstry RC, Shimony JS, Jones BV, Mangano FT, Holland SK, Yuan W, Limbrick DD Jr
J Neurosurg Pediatr. 2015 Jun; 15(6)547-51. doi: 10.3171/2014.10.PEDS14209.

PMID:
    25745953
    [PubMed - indexed for MEDLINE]
Related citations


Prediction of brain maturity based on cortical thickness at different spatial resolutions.
Khundrakpam BS, Tohka J, Evans AC, Brain Development Cooperative Group
Neuroimage. 2015 May 1; 111350-9. doi: 10.1016/j.neuroimage.2015.02.046.

PMID:
    25731999
    [PubMed - indexed for MEDLINE]
Related citations


Accurate age classification of 6 and 12 month-old infants based on resting-state functional connectivity magnetic resonance imaging data.
Pruett JR Jr, Kandala S, Hoertel S, Snyder AZ, Elison JT, Nishino T, Feczko E, Dosenbach NU, Nardos B, Power JD, Adeyemo B, Botteron KN, McKinstry RC, Evans AC, Hazlett HC, Dager SR, Paterson S, Schultz RT, Collins DL, Fonov VS, Styner M, Gerig G, Das S, Kostopoulos P, Constantino JN, Estes AM, IBIS Network, Petersen SE, Schlaggar BL, Piven J
Dev Cogn Neurosci. 2015 Apr; 12123-33. doi: 10.1016/j.dcn.2015.01.003.

PMID:
    25704288
    [PubMed - indexed for MEDLINE]
Related citations


Diffusion MRI quality control and functional diffusion map results in ACRIN 6677/RTOG 0625: a multicenter, randomized, phase II trial of bevacizumab and chemotherapy in recurrent glioblastoma.
Ellingson BM, Kim E, Woodworth DC, Marques H, Boxerman JL, Safriel Y, McKinstry RC, Bokstein F, Jain R, Chi TL, Sorensen AG, Gilbert MR, Barboriak DP
Int J Oncol. 2015 May; 46(5)1883-92. doi: 10.3892/ijo.2015.2891.

PMID:
    25672376
    [PubMed - indexed for MEDLINE]
Related citations


Prolonged exposure to high and variable phenylalanine levels over the lifetime predicts brain white matter integrity in children with phenylketonuria.
Hood A, Antenor-Dorsey JA, Rutlin J, Hershey T, Shimony JS, McKinstry RC, Grange DK, Christ SE, Steiner R, White DA
Mol Genet Metab. 2015 Jan; 114(1)19-24. doi: 10.1016/j.ymgme.2014.11.007.

PMID:
    25481106
    [PubMed - indexed for MEDLINE]
Related citations


The cyclic AMP pathway is a sex-specific modifier of glioma risk in type I neurofibromatosis patients.
Warrington NM, Sun T, Luo J, McKinstry RC, Parkin PC, Ganzhorn S, Spoljaric D, Albers AC, Merkelson A, Stewart DR, Stevenson DA, Viskochil D, Druley TE, Forys JT, Reilly KM, Fisher MJ, Tabori U, Allen JC, Schiffman JD, Gutmann DH, Rubin JB
Cancer Res. 2015 Jan 1; 75(1)16-21. doi: 10.1158/0008-5472.CAN-14-1891.

PMID:
    25381154
    [PubMed - indexed for MEDLINE]
Related citations