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Robert C. McKinstry III, MD, PhD

Professor, Radiology
Division of Diagnostic Radiology
Pediatric Radiology and Neuroradiology Sections
Chief, Pediatric Radiology
Professor, Pediatrics

Specialty Areas

Pediatric Neuroradiology
Neuroradiology
Neuro Oncology
Radiology
Pediatric Radiology

Board Certifications

Radiology
Neuroradiology

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Magnetic resonance imaging, MRI, MR imaging of brain development, diffusion tensor imaging, perfusion MR imaging and functional MR imaging, functional neuroimaging with magnetic resonance

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish Hospital
Mallinckrodt Institute of Radiology

510 South Kingshighway Boulevard
St. Louis, MO 63110

Office Phone: 314-362-5949
Fax: 314-362-4886

Education

Education

Fellowship: Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri 1999
Residency: Mallinckrodt Institute of Radiology and Barnes-Jewish Hospital, St. Louis, Missouri 1997
Medical Degree: Harvard-MIT Division of Health Sciences & Technology, Harvard Medical School, Boston, Massachusetts 1992
Ph.D.: Radiological Sciences, Massachusetts Institute of Technology, Boston, Massachusetts 1991
B.S.: Boston University, Boston, Massachusetts 1984

Publication & Research

Publication & Research

Early brain development in infants at high risk for autism spectrum disorder.
Hazlett HC, Gu H, Munsell BC, Kim SH, Styner M, Wolff JJ, Elison JT, Swanson MR, Zhu H, Botteron KN, Collins DL, Constantino JN, Dager SR, Estes AM, Evans AC, Fonov VS, Gerig G, Kostopoulos P, McKinstry RC, Pandey J, Paterson S, Pruett JR, Schultz RT, Shaw DW, Zwaigenbaum L, Piven J, IBIS Network., Clinical Sites., Data Coordinating Center., Image Processing Core., Statistical Analysis.
Nature. 2017 Feb 15; 542(7641)348-351. doi: 10.1038/nature21369.

PMID:
    28202961
    [PubMed - in process]
Related citations


Large-Vessel Vasculopathy in Children With Sickle Cell Disease: A Magnetic Resonance Imaging Study of Infarct Topography and Focal Atrophy.
Guilliams KP, Fields ME, Ragan DK, Chen Y, Eldeniz C, Hulbert ML, Binkley MM, Rhodes JN, Shimony JS, McKinstry RC, Vo KD, An H, Lee JM, Ford AL
Pediatr Neurol. 2016 Dec 7; pii: S0887-8994(16)30739-1. doi: 10.1016/j.pediatrneurol.2016.11.005.

PMID:
    28159432
    [PubMed - as supplied by publisher]
Related citations


Joint Attention and Brain Functional Connectivity in Infants and Toddlers.
Eggebrecht AT, Elison JT, Feczko E, Todorov A, Wolff JJ, Kandala S, Adams CM, Snyder AZ, Lewis JD, Estes AM, Zwaigenbaum L, Botteron KN, McKinstry RC, Constantino JN, Evans A, Hazlett HC, Dager S, Paterson SJ, Schultz RT, Styner MA, Gerig G, Das S, Kostopoulos P, Schlaggar BL, Petersen SE, Piven J, Pruett JR Jr, IBIS Network .
Cereb Cortex. 2017 Jan 6; doi: 10.1093/cercor/bhw403.

PMID:
    28062515
    [PubMed - as supplied by publisher]
Related citations


Neurologic Injury in Acidemic Term Infants.
Cahill AG, Mathur AM, Smyser CD, Mckinstry RC, Roehl KA, López JD, Inder TE, Macones GA
Am J Perinatol. 2016 Dec 7;

PMID:
    27926973
    [PubMed - as supplied by publisher]
Related citations


Left hemisphere structural connectivity abnormality in pediatric hydrocephalus patients following surgery.
Yuan W, Meller A, Shimony JS, Nash T, Jones BV, Holland SK, Altaye M, Barnard H, Phillips J, Powell S, McKinstry RC, Limbrick DD, Rajagopal A, Mangano FT
Neuroimage Clin. 2016 Sep 4; 12631-639.

PMID:
    27722087
    [PubMed - in process]
Related citations


Changes of White Matter Diffusion Anisotropy in Response to a 6-Week iPad Application-Based Occupational Therapy Intervention in Children with Surgically Treated Hydrocephalus: A Pilot Study.
Yuan W, Harpster K, Jones BV, Shimony JS, McKinstry RC, Weckherlin N, Powell SS, Barnard H, Engsberg J, Kadis DS, Dodd J, Altaye M, Limbrick DD, Holland SK, Simpson SM, Bidwell S, Mangano FT
Neuropediatrics. 2016 Oct; 47(5)336-40. doi: 10.1055/s-0036-1584938.

PMID:
    27438376
    [PubMed - in process]
Related citations


Anxious/depressed symptoms are related to microstructural maturation of white matter in typically developing youths.
Albaugh MD, Ducharme S, Karama S, Watts R, Lewis JD, Orr C, Nguyen TV, Mckinstry RC, Botteron KN, Evans AC, Hudziak JJ, Brain Development Cooperative Group.
Dev Psychopathol. 2016 Jun 14; 1-8.

PMID:
    27297294
    [PubMed - as supplied by publisher]
Related citations


High-Dose Erythropoietin and Hypothermia for Hypoxic-Ischemic Encephalopathy: A Phase II Trial.
Wu YW, Mathur AM, Chang T, McKinstry RC, Mulkey SB, Mayock DE, Van Meurs KP, Rogers EE, Gonzalez FF, Comstock BA, Juul SE, Msall ME, Bonifacio SL, Glass HC, Massaro AN, Dong L, Tan KW, Heagerty PJ, Ballard RA
Pediatrics. 2016 Jun; 137(6)pii: e20160191. doi: 10.1542/peds.2016-0191.

PMID:
    27244862
    [PubMed - in process]
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Diffusion tensor imaging study of pediatric patients with congenital hydrocephalus: 1-year postsurgical outcomes.
Mangano FT, Altaye M, McKinstry RC, Shimony JS, Powell SK, Phillips JM, Barnard H, Limbrick DD Jr, Holland SK, Jones BV, Dodd J, Simpson S, Mercer D, Rajagopal A, Bidwell S, Yuan W
J Neurosurg Pediatr. 2016 Sep; 18(3)306-19. doi: 10.3171/2016.2.PEDS15628.

PMID:
    27203134
    [PubMed - indexed for MEDLINE]
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Development of cortical shape in the human brain from 6 to 24months of age via a novel measure of shape complexity.
Kim SH, Lyu I, Fonov VS, Vachet C, Hazlett HC, Smith RG, Piven J, Dager SR, Mckinstry RC, Pruett JR Jr, Evans AC, Collins DL, Botteron KN, Schultz RT, Gerig G, Styner MA, IBIS Network.
Neuroimage. 2016 Jul 15; 135163-76. doi: 10.1016/j.neuroimage.2016.04.053.

PMID:
    27150231
    [PubMed - in process]
Related citations


Brain atrophy in paediatric sickle cell anaemia: findings from the silent infarct transfusion (SIT) trial.
Kawadler JM, Clark CA, McKinstry RC, Kirkham FJ
Br J Haematol. 2016 Apr 7; doi: 10.1111/bjh.14039.

PMID:
    27061199
    [PubMed - as supplied by publisher]
Related citations


De novo development of gliomas in a child with neurofibromatosis type 1, fragile X and previously normal brain magnetic resonance imaging.
Zafar R, Hsiao EY, Botteron KN, McKinstry RC, Gutmann DH
Radiol Case Rep. 2016 Feb 2; 11(1)33-5. doi: 10.1016/j.radcr.2015.12.008.

PMID:
    26973730
    [PubMed]
Related citations


Splenium development and early spoken language in human infants.
Swanson MR, Wolff JJ, Elison JT, Gu H, Hazlett HC, Botteron K, Styner M, Paterson S, Gerig G, Constantino J, Dager S, Estes A, Vachet C, Piven J, IBIS Network.
Dev Sci. 2015 Oct 21; doi: 10.1111/desc.12360.

PMID:
    26490257
    [PubMed - as supplied by publisher]
Related citations


Trajectories of cortical thickness maturation in normal brain development--The importance of quality control procedures.
Ducharme S, Albaugh MD, Nguyen TV, Hudziak JJ, Mateos-Pérez JM, Labbe A, Evans AC, Karama S, Brain Development Cooperative Group.
Neuroimage. 2016 Jan 15; 125267-79. doi: 10.1016/j.neuroimage.2015.10.010.

PMID:
    26463175
    [PubMed - indexed for MEDLINE]
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CT Dose Optimization in Pediatric Radiology: A Multiyear Effort to Preserve the Benefits of Imaging While Reducing the Risks.
Greenwood TJ, Lopez-Costa RI, Rhoades PD, Ramírez-Giraldo JC, Starr M, Street M, Duncan J, McKinstry RC
Radiographics. 2015 Sep-Oct; 35(5)1539-54. doi: 10.1148/rg.2015140267.

PMID:
    26267677
    [PubMed - indexed for MEDLINE]
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Abnormal structural connectivity in the brain networks of children with hydrocephalus.
Yuan W, Holland SK, Shimony JS, Altaye M, Mangano FT, Limbrick DD, Jones BV, Nash T, Rajagopal A, Simpson S, Ragan D, McKinstry RC
Neuroimage Clin. 2015 Apr 29; 8483-92. doi: 10.1016/j.nicl.2015.04.015.

PMID:
    26106573
    [PubMed - indexed for MEDLINE]
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The diffusion tensor imaging (DTI) component of the NIH MRI study of normal brain development (PedsDTI).
Walker L, Chang LC, Nayak A, Irfanoglu MO, Botteron KN, McCracken J, McKinstry RC, Rivkin MJ, Wang DJ, Rumsey J, Pierpaoli C, Brain Development Cooperative Group.
Neuroimage. 2016 Jan 1; 124(Pt B)1125-30. doi: 10.1016/j.neuroimage.2015.05.083.

PMID:
    26048622
    [PubMed - indexed for MEDLINE]
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Periventricular hyperintensity in children with hydrocephalus.
Akbari SH, Limbrick DD Jr, McKinstry RC, Altaye M, Ragan DK, Yuan W, Mangano FT, Holland SK, Shimony JS
Pediatr Radiol. 2015 Jul; 45(8)1189-97. doi: 10.1007/s00247-015-3298-8.

PMID:
    25779827
    [PubMed - indexed for MEDLINE]
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Evaluation of the use of automatic exposure control and automatic tube potential selection in low-dose cerebrospinal fluid shunt head CT.
Wallace AN, Vyhmeister R, Bagade S, Chatterjee A, Hicks B, Ramirez-Giraldo JC, McKinstry RC
Neuroradiology. 2015 Jun; 57(6)639-44. doi: 10.1007/s00234-015-1508-6.

PMID:
    25779098
    [PubMed - indexed for MEDLINE]
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The accuracy of linear indices of ventricular volume in pediatric hydrocephalus: technical note.
Ragan DK, Cerqua J, Nash T, McKinstry RC, Shimony JS, Jones BV, Mangano FT, Holland SK, Yuan W, Limbrick DD Jr
J Neurosurg Pediatr. 2015 Jun; 15(6)547-51. doi: 10.3171/2014.10.PEDS14209.

PMID:
    25745953
    [PubMed - indexed for MEDLINE]
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