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Robert C. McKinstry III, MD, PhD

Professor, Radiology
Director, Division of Diagnostic Radiology
Pediatric Radiology and Neuroradiology Sections
Professor, Pediatrics

Specialty Areas

Pediatric Neuroradiology
Neuroradiology
Neuro Oncology
Radiology
Pediatric Radiology

Board Certifications

Radiology
Neuroradiology

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Magnetic resonance imaging, MRI, MR imaging of brain development, diffusion tensor imaging, perfusion MR imaging and functional MR imaging, functional neuroimaging with magnetic resonance

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish Hospital
Mallinckrodt Institute of Radiology

510 South Kingshighway Boulevard
St. Louis, MO 63110

Office Phone: 314-362-5949
Fax: 314-362-4886

Education

Education

Fellowship: Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri 1999
Residency: Mallinckrodt Institute of Radiology and Barnes-Jewish Hospital, St. Louis, Missouri 1997
Medical Degree: Harvard-MIT Division of Health Sciences & Technology, Harvard Medical School, Boston, Massachusetts 1992
Ph.D.: Radiological Sciences, Massachusetts Institute of Technology, Boston, Massachusetts 1991
B.S.: Boston University, Boston, Massachusetts 1984

Publication & Research

Publication & Research

Intracranial vasculopathy and infarct recurrence in children with sickle cell anaemia, silent cerebral infarcts and normal transcranial Doppler velocities.
Choudhury NA, DeBaun MR, Ponisio MR, Jordan LC, Rodeghier M, Pruthi S, McKinstry RC
Br J Haematol. 2017 Oct 26; doi: 10.1111/bjh.14979.

PMID:
    29076125
    [PubMed - as supplied by publisher]
Related citations


CEDNIK: Phenotypic and Molecular Characterization of an Additional Patient and Review of the Literature.
Hsu T, Coughlin CC, Monaghan KG, Fiala E, McKinstry RC, Paciorkowski AR, Shinawi M
Child Neurol Open. 2017 Jan-Dec; 42329048X17733214. doi: 10.1177/2329048X17733214.

PMID:
    29051910
    [PubMed]
Related citations


A validated clinical MRI injury scoring system in neonatal hypoxic-ischemic encephalopathy.
Trivedi SB, Vesoulis ZA, Rao R, Liao SM, Shimony JS, McKinstry RC, Mathur AM
Pediatr Radiol. 2017 Oct; 47(11)1491-1499. doi: 10.1007/s00247-017-3893-y.

PMID:
    28623417
    [PubMed - in process]
Related citations


Functional neuroimaging of high-risk 6-month-old infants predicts a diagnosis of autism at 24 months of age.
Emerson RW, Adams C, Nishino T, Hazlett HC, Wolff JJ, Zwaigenbaum L, Constantino JN, Shen MD, Swanson MR, Elison JT, Kandala S, Estes AM, Botteron KN, Collins L, Dager SR, Evans AC, Gerig G, Gu H, McKinstry RC, Paterson S, Schultz RT, Styner M, IBIS Network., Schlaggar BL, Pruett JR Jr, Piven J
Sci Transl Med. 2017 Jun 7; 9(393)pii: eaag2882. doi: 10.1126/scitranslmed.aag2882.

PMID:
    28592562
    [PubMed - in process]
Related citations


The Emergence of Network Inefficiencies in Infants With Autism Spectrum Disorder.
Lewis JD, Evans AC, Pruett JR Jr, Botteron KN, McKinstry RC, Zwaigenbaum L, Estes AM, Collins DL, Kostopoulos P, Gerig G, Dager SR, Paterson S, Schultz RT, Styner MA, Hazlett HC, Piven J, Infant Brain Imaging Study Network.
Biol Psychiatry. 2017 Aug 1; 82(3)176-185. doi: 10.1016/j.biopsych.2017.03.006.

PMID:
    28460842
    [PubMed - in process]
Related citations


Erythropoietin and Brain Magnetic Resonance Imaging Findings in Hypoxic-Ischemic Encephalopathy: Volume of Acute Brain Injury and 1-Year Neurodevelopmental Outcome.
Mulkey SB, Ramakrishnaiah RH, McKinstry RC, Chang T, Mathur AM, Mayock DE, Van Meurs KP, Schaefer GB, Luo C, Bai S, Juul SE, Wu YW
J Pediatr. 2017 Jul; 186196-199. doi: 10.1016/j.jpeds.2017.03.053.

PMID:
    28456387
    [PubMed - indexed for MEDLINE]
Related citations


Increased Extra-axial Cerebrospinal Fluid in High-Risk Infants Who Later Develop Autism.
Shen MD, Kim SH, McKinstry RC, Gu H, Hazlett HC, Nordahl CW, Emerson RW, Shaw D, Elison JT, Swanson MR, Fonov VS, Gerig G, Dager SR, Botteron KN, Paterson S, Schultz RT, Evans AC, Estes AM, Zwaigenbaum L, Styner MA, Amaral DG, Piven J, Infant Brain Imaging Study Network., Infant Brain Imaging Study Network, The Infant Brain Imaging Study (IBIS) Network is a National Institutes of Health–funded Autism Center of Excellence project and consists of a consortium of eight universities in the United States and Canada., Piven J, Hazlett HC, Chappell C, Dager S, Estes A, Shaw D, Botteron K, McKinstry R, Constantino J, Pruett J, Schultz R, Zwaigenbaum L, Elison J, Evans AC, Collins DL, Pike GB, Fonov V, Kostopoulos P, Das S, Gerig G, Styner M, Gu H
Biol Psychiatry. 2017 Aug 1; 82(3)186-193. doi: 10.1016/j.biopsych.2017.02.1095.

PMID:
    28392081
    [PubMed - in process]
Related citations


A multi-institutional study of brainstem gliomas in children with neurofibromatosis type 1.
Mahdi J, Shah AC, Sato A, Morris SM, McKinstry RC, Listernick R, Packer RJ, Fisher MJ, Gutmann DH
Neurology. 2017 Apr 18; 88(16)1584-1589. doi: 10.1212/WNL.0000000000003881.

PMID:
    28330960
    [PubMed - indexed for MEDLINE]
Related citations


Early brain development in infants at high risk for autism spectrum disorder.
Hazlett HC, Gu H, Munsell BC, Kim SH, Styner M, Wolff JJ, Elison JT, Swanson MR, Zhu H, Botteron KN, Collins DL, Constantino JN, Dager SR, Estes AM, Evans AC, Fonov VS, Gerig G, Kostopoulos P, McKinstry RC, Pandey J, Paterson S, Pruett JR, Schultz RT, Shaw DW, Zwaigenbaum L, Piven J, IBIS Network., Clinical Sites., Data Coordinating Center., Image Processing Core., Statistical Analysis.
Nature. 2017 Feb 15; 542(7641)348-351. doi: 10.1038/nature21369.

PMID:
    28202961
    [PubMed - indexed for MEDLINE]
Related citations


Large-Vessel Vasculopathy in Children With Sickle Cell Disease: A Magnetic Resonance Imaging Study of Infarct Topography and Focal Atrophy.
Guilliams KP, Fields ME, Ragan DK, Chen Y, Eldeniz C, Hulbert ML, Binkley MM, Rhodes JN, Shimony JS, McKinstry RC, Vo KD, An H, Lee JM, Ford AL
Pediatr Neurol. 2017 Apr; 6949-57. doi: 10.1016/j.pediatrneurol.2016.11.005.

PMID:
    28159432
    [PubMed - in process]
Related citations


Joint Attention and Brain Functional Connectivity in Infants and Toddlers.
Eggebrecht AT, Elison JT, Feczko E, Todorov A, Wolff JJ, Kandala S, Adams CM, Snyder AZ, Lewis JD, Estes AM, Zwaigenbaum L, Botteron KN, McKinstry RC, Constantino JN, Evans A, Hazlett HC, Dager S, Paterson SJ, Schultz RT, Styner MA, Gerig G, Das S, Kostopoulos P, IBIS Network†., Schlaggar BL, Petersen SE, Piven J, Pruett JR Jr
Cereb Cortex. 2017 Mar 1; 27(3)1709-1720. doi: 10.1093/cercor/bhw403.

PMID:
    28062515
    [PubMed - indexed for MEDLINE]
Related citations


Neurologic Injury in Acidemic Term Infants.
Cahill AG, Mathur AM, Smyser CD, Mckinstry RC, Roehl KA, López JD, Inder TE, Macones GA
Am J Perinatol. 2017 Jun; 34(7)668-675. doi: 10.1055/s-0036-1597135.

PMID:
    27926973
    [PubMed - in process]
Related citations


Left hemisphere structural connectivity abnormality in pediatric hydrocephalus patients following surgery.
Yuan W, Meller A, Shimony JS, Nash T, Jones BV, Holland SK, Altaye M, Barnard H, Phillips J, Powell S, McKinstry RC, Limbrick DD, Rajagopal A, Mangano FT
Neuroimage Clin. 2016; 12631-639.

PMID:
    27722087
    [PubMed - in process]
Related citations


Changes of White Matter Diffusion Anisotropy in Response to a 6-Week iPad Application-Based Occupational Therapy Intervention in Children with Surgically Treated Hydrocephalus: A Pilot Study.
Yuan W, Harpster K, Jones BV, Shimony JS, McKinstry RC, Weckherlin N, Powell SS, Barnard H, Engsberg J, Kadis DS, Dodd J, Altaye M, Limbrick DD, Holland SK, Simpson SM, Bidwell S, Mangano FT
Neuropediatrics. 2016 Oct; 47(5)336-40. doi: 10.1055/s-0036-1584938.

PMID:
    27438376
    [PubMed - indexed for MEDLINE]
Related citations


Anxious/depressed symptoms are related to microstructural maturation of white matter in typically developing youths.
Albaugh MD, Ducharme S, Karama S, Watts R, Lewis JD, Orr C, Nguyen TV, Mckinstry RC, Botteron KN, Evans AC, Hudziak JJ, Brain Development Cooperative Group.
Dev Psychopathol. 2017 Aug; 29(3)751-758. doi: 10.1017/S0954579416000444.

PMID:
    27297294
    [PubMed - in process]
Related citations


High-Dose Erythropoietin and Hypothermia for Hypoxic-Ischemic Encephalopathy: A Phase II Trial.
Wu YW, Mathur AM, Chang T, McKinstry RC, Mulkey SB, Mayock DE, Van Meurs KP, Rogers EE, Gonzalez FF, Comstock BA, Juul SE, Msall ME, Bonifacio SL, Glass HC, Massaro AN, Dong L, Tan KW, Heagerty PJ, Ballard RA
Pediatrics. 2016 Jun; 137(6)pii: e20160191. doi: 10.1542/peds.2016-0191.

PMID:
    27244862
    [PubMed - indexed for MEDLINE]
Related citations


Diffusion tensor imaging study of pediatric patients with congenital hydrocephalus: 1-year postsurgical outcomes.
Mangano FT, Altaye M, McKinstry RC, Shimony JS, Powell SK, Phillips JM, Barnard H, Limbrick DD Jr, Holland SK, Jones BV, Dodd J, Simpson S, Mercer D, Rajagopal A, Bidwell S, Yuan W
J Neurosurg Pediatr. 2016 Sep; 18(3)306-19. doi: 10.3171/2016.2.PEDS15628.

PMID:
    27203134
    [PubMed - indexed for MEDLINE]
Related citations


Development of cortical shape in the human brain from 6 to 24months of age via a novel measure of shape complexity.
Kim SH, Lyu I, Fonov VS, Vachet C, Hazlett HC, Smith RG, Piven J, Dager SR, Mckinstry RC, Pruett JR Jr, Evans AC, Collins DL, Botteron KN, Schultz RT, Gerig G, Styner MA, IBIS Network.
Neuroimage. 2016 Jul 15; 135163-76. doi: 10.1016/j.neuroimage.2016.04.053.

PMID:
    27150231
    [PubMed - in process]
Related citations


Brain atrophy in paediatric sickle cell anaemia: findings from the silent infarct transfusion (SIT) trial.
Kawadler JM, Clark CA, McKinstry RC, Kirkham FJ
Br J Haematol. 2017 Apr; 177(1)151-153. doi: 10.1111/bjh.14039.

PMID:
    27061199
    [PubMed - in process]
Related citations


De novo development of gliomas in a child with neurofibromatosis type 1, fragile X and previously normal brain magnetic resonance imaging.
Zafar R, Hsiao EY, Botteron KN, McKinstry RC, Gutmann DH
Radiol Case Rep. 2016 Mar; 11(1)33-5. doi: 10.1016/j.radcr.2015.12.008.

PMID:
    26973730
    [PubMed]
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