Patient Portal

Ramaswamy Govindan, MD

Professor, Medicine
Division of Medical Oncology

Specialty Areas

Medical Oncology
Esophageal Cancer
Pulmonary Oncology
Lung Cancer

Board Certifications

Hematology
Internal Medicine
Medical Oncology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Esophageal, thoracic and lung cancer

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Siteman Cancer Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 7
Office Phone: 314-747-1171
Fax: 314-362-3895

Education

Education

Fellowship: Hematology - Oncology at Washington University School of Medicine, St. Louis, MO
Residency: Internal Medicine at Michael Reese Hospital and Medical Center, Chicago, IL
Residency: Internal Medicine at JIPMER, India
Medical Degree: University of Madras, Madras, India 1987
B.S.: SIR. MCTM Higher Secondary School, Madras, India 1980

Publication & Research

Publication & Research

Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer.
Wagner AH, Devarakonda S, Skidmore ZL, Krysiak K, Ramu A, Trani L, Kunisaki J, Masood A, Waqar SN, Spies NC, Morgensztern D, Waligorski J, Ponce J, Fulton RS, Maggi LB Jr, Weber JD, Watson MA, O'Conor CJ, Ritter JH, Olsen RR, Cheng H, Mukhopadhyay A, Can I, Cessna MH, Oliver TG, Mardis ER, Wilson RK, Griffith M, Griffith OL, Govindan R
Nat Commun. 2018 Sep 17; 9(1)3787. doi: 10.1038/s41467-018-06162-9.

PMID:
    30224629
    [PubMed - in process]
Related citations


Ensuring signal quality of cerebral near infrared spectroscopy during continuous longterm monitoring.
Govindan RB, Massaro AN, du Plessis A
J Neurosci Methods. 2018 Sep 4; 309147-152. doi: 10.1016/j.jneumeth.2018.09.003.

PMID:
    30189283
    [PubMed - as supplied by publisher]
Related citations


Tumor Mutation Burden as a Biomarker in Resected Non-Small-Cell Lung Cancer.
Devarakonda S, Rotolo F, Tsao MS, Lanc I, Brambilla E, Masood A, Olaussen KA, Fulton R, Sakashita S, McLeer-Florin A, Ding K, Le Teuff G, Shepherd FA, Pignon JP, Graziano SL, Kratzke R, Soria JC, Seymour L, Govindan R, Michiels S
J Clin Oncol. 2018 Aug 14; JCO2018781963. doi: 10.1200/JCO.2018.78.1963.

PMID:
    30106638
    [PubMed - as supplied by publisher]
Related citations


Comprehensive Characterization of Cancer Driver Genes and Mutations.
Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Kwok-Shing Ng P, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortés-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H, MC3 Working Group., Cancer Genome Atlas Research Network., Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J, Wheeler D, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L
Cell. 2018 Aug 9; 174(4)1034-1035. doi: 10.1016/j.cell.2018.07.034.

PMID:
    30096302
    [PubMed - in process]
Related citations


Phase Ib/II study of the pan-cyclin-dependent kinase inhibitor roniciclib in combination with chemotherapy in patients with extensive-disease small-cell lung cancer.
Cho BC, Dy GK, Govindan R, Kim DW, Pennell NA, Zalcman G, Besse B, Kim JH, Koca G, Rajagopalan P, Langer S, Ocker M, Nogai H, Barlesi F
Lung Cancer. 2018 Sep; 12314-21. doi: 10.1016/j.lungcan.2018.04.022.

PMID:
    30089585
    [PubMed - in process]
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Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.
Kahles A, Lehmann KV, Toussaint NC, Hüser M, Stark SG, Sachsenberg T, Stegle O, Kohlbacher O, Sander C, Cancer Genome Atlas Research Network., Rätsch G
Cancer Cell. 2018 Aug 13; 34(2)211-224.e6. doi: 10.1016/j.ccell.2018.07.001.

PMID:
    30078747
    [PubMed - in process]
Related citations


Autonomic nervous system depression at term in neurologically normal premature infants.
Mulkey SB, Kota S, Swisher CB, Hitchings L, Metzler M, Wang Y, Maxwell GL, Baker R, du Plessis AJ, Govindan R
Early Hum Dev. 2018 Aug; 12311-16. doi: 10.1016/j.earlhumdev.2018.07.003.

PMID:
    30025221
    [PubMed - in process]
Related citations


Proteogenomic Analysis of Surgically Resected Lung Adenocarcinoma.
Sharpnack MF, Ranbaduge N, Srivastava A, Cerciello F, Codreanu SG, Liebler DC, Mascaux C, Miles WO, Morris R, McDermott JE, Sharpnack JL, Amann J, Maher CA, Machiraju R, Wysocki VH, Govindan R, Mallick P, Coombes KR, Huang K, Carbone DP
J Thorac Oncol. 2018 Jul 11; pii: S1556-0864(18)30784-6. doi: 10.1016/j.jtho.2018.06.025.

PMID:
    30017829
    [PubMed - as supplied by publisher]
Related citations


The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of non-small cell lung cancer (NSCLC).
Brahmer JR, Govindan R, Anders RA, Antonia SJ, Sagorsky S, Davies MJ, Dubinett SM, Ferris A, Gandhi L, Garon EB, Hellmann MD, Hirsch FR, Malik S, Neal JW, Papadimitrakopoulou VA, Rimm DL, Schwartz LH, Sepesi B, Yeap BY, Rizvi NA, Herbst RS
J Immunother Cancer. 2018 Jul 17; 6(1)75. doi: 10.1186/s40425-018-0382-2.

PMID:
    30012210
    [PubMed - in process]
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NCCN Guidelines Insights: Non-Small Cell Lung Cancer, Version 5.2018.
Ettinger DS, Aisner DL, Wood DE, Akerley W, Bauman J, Chang JY, Chirieac LR, D'Amico TA, Dilling TJ, Dobelbower M, Govindan R, Gubens MA, Hennon M, Horn L, Lackner RP, Lanuti M, Leal TA, Lilenbaum R, Lin J, Loo BW Jr, Martins R, Otterson GA, Patel SP, Reckamp K, Riely GJ, Schild SE, Shapiro TA, Stevenson J, Swanson SJ, Tauer K, Yang SC, Gregory K, Hughes M
J Natl Compr Canc Netw. 2018 Jul; 16(7)807-821. doi: 10.6004/jnccn.2018.0062.

PMID:
    30006423
    [PubMed - in process]
Related citations


Direct Visualization of the Conformational Dynamics of Single Influenza Hemagglutinin Trimers.
Das DK, Govindan R, Nikić-Spiegel I, Krammer F, Lemke EA, Munro JB
Cell. 2018 Aug 9; 174(4)926-937.e12. doi: 10.1016/j.cell.2018.05.050.

PMID:
    29961575
    [PubMed - in process]
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The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.
Ricketts CJ, De Cubas AA, Fan H, Smith CC, Lang M, Reznik E, Bowlby R, Gibb EA, Akbani R, Beroukhim R, Bottaro DP, Choueiri TK, Gibbs RA, Godwin AK, Haake S, Hakimi AA, Henske EP, Hsieh JJ, Ho TH, Kanchi RS, Krishnan B, Kwiatkowski DJ, Lui W, Merino MJ, Mills GB, Myers J, Nickerson ML, Reuter VE, Schmidt LS, Shelley CS, Shen H, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Vincent BG, Vocke CD, Wheeler DA, Yang L, Kim WY, Robertson AG, Cancer Genome Atlas Research Network., Spellman PT, Rathmell WK, Linehan WM
Cell Rep. 2018 Jun 19; 23(12)3698. doi: 10.1016/j.celrep.2018.06.032.

PMID:
    29925010
    [PubMed - in process]
Related citations


The Impact of Staging by Positron-Emission Tomography on Overall Survival and Progression-Free Survival in Patients With Locally Advanced NSCLC.
Vokes EE, Govindan R, Iscoe N, Hossain AM, San Antonio B, Chouaki N, Koczywas M, Senan S
J Thorac Oncol. 2018 Aug; 13(8)1183-1188. doi: 10.1016/j.jtho.2018.04.028.

PMID:
    29733908
    [PubMed - in process]
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Four-mirror flat-field anastigmat aplanat telescopes with simple closed-form solutions.
Govindan R
J Opt Soc Am A Opt Image Sci Vis. 2018 May 1; 35(5)779-784. doi: 10.1364/JOSAA.35.000779.

PMID:
    29726483
    [PubMed]
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The Immune Landscape of Cancer.
Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CE, Cancer Genome Atlas Research Network., Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich L
Immunity. 2018 Apr 17; 48(4)812-830.e14. doi: 10.1016/j.immuni.2018.03.023.

PMID:
    29628290
    [PubMed - in process]
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An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics.
Liu J, Lichtenberg T, Hoadley KA, Poisson LM, Lazar AJ, Cherniack AD, Kovatich AJ, Benz CC, Levine DA, Lee AV, Omberg L, Wolf DM, Shriver CD, Thorsson V, Cancer Genome Atlas Research Network., Hu H
Cell. 2018 Apr 5; 173(2)400-416.e11. doi: 10.1016/j.cell.2018.02.052.

PMID:
    29625055
    [PubMed - in process]
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A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples.
Chen H, Li C, Peng X, Zhou Z, Weinstein JN, Cancer Genome Atlas Research Network., Liang H
Cell. 2018 Apr 5; 173(2)386-399.e12. doi: 10.1016/j.cell.2018.03.027.

PMID:
    29625054
    [PubMed - in process]
Related citations


Comprehensive Characterization of Cancer Driver Genes and Mutations.
Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Ng PK, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortés-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H, MC3 Working Group., Cancer Genome Atlas Research Network., Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J, Wheeler D, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L
Cell. 2018 Apr 5; 173(2)371-385.e18. doi: 10.1016/j.cell.2018.02.060.

PMID:
    29625053
    [PubMed - in process]
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Pathogenic Germline Variants in 10,389 Adult Cancers.
Huang KL, Mashl RJ, Wu Y, Ritter DI, Wang J, Oh C, Paczkowska M, Reynolds S, Wyczalkowski MA, Oak N, Scott AD, Krassowski M, Cherniack AD, Houlahan KE, Jayasinghe R, Wang LB, Zhou DC, Liu D, Cao S, Kim YW, Koire A, McMichael JF, Hucthagowder V, Kim TB, Hahn A, Wang C, McLellan MD, Al-Mulla F, Johnson KJ, Cancer Genome Atlas Research Network., Lichtarge O, Boutros PC, Raphael B, Lazar AJ, Zhang W, Wendl MC, Govindan R, Jain S, Wheeler D, Kulkarni S, Dipersio JF, Reimand J, Meric-Bernstam F, Chen K, Shmulevich I, Plon SE, Chen F, Ding L
Cell. 2018 Apr 5; 173(2)355-370.e14. doi: 10.1016/j.cell.2018.03.039.

PMID:
    29625052
    [PubMed - in process]
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Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.
Malta TM, Sokolov A, Gentles AJ, Burzykowski T, Poisson L, Weinstein JN, Kamińska B, Huelsken J, Omberg L, Gevaert O, Colaprico A, Czerwińska P, Mazurek S, Mishra L, Heyn H, Krasnitz A, Godwin AK, Lazar AJ, Cancer Genome Atlas Research Network., Stuart JM, Hoadley KA, Laird PW, Noushmehr H, Wiznerowicz M
Cell. 2018 Apr 5; 173(2)338-354.e15. doi: 10.1016/j.cell.2018.03.034.

PMID:
    29625051
    [PubMed - in process]
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