Patient Portal

Ramaswamy Govindan, MD

Professor, Medicine
Division of Medical Oncology

Specialty Areas

Medical Oncology
Esophageal Cancer
Pulmonary Oncology
Lung Cancer

Board Certifications

Hematology
Internal Medicine
Medical Oncology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Esophageal, thoracic and lung cancer

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

Center for Advanced Medicine
Siteman Cancer Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 7
Office Phone: 314-747-1171
Fax: 314-362-3895

Education

Education

Fellowship: Hematology - Oncology at Washington University School of Medicine, St. Louis, MO
Residency: Internal Medicine at Michael Reese Hospital and Medical Center, Chicago, IL
Residency: Internal Medicine at JIPMER, India
Medical Degree: University of Madras, Madras, India 1987
B.S.: SIR. MCTM Higher Secondary School, Madras, India 1980

Publication & Research

Publication & Research

Pooled overall survival and safety data from the pivotal phase II studies (NP28673 and NP28761) of alectinib in ALK-positive non-small-cell lung cancer.
Ou SI, Gadgeel SM, Barlesi F, Yang JC, De Petris L, Kim DW, Govindan R, Dingemans AM, Crino L, Léna H, Popat S, Ahn JS, Dansin E, Mitry E, Müller B, Bordogna W, Balas B, Morcos PN, Shaw AT
Lung Cancer. 2019 Oct 14; 13922-27. doi: 10.1016/j.lungcan.2019.10.015.

PMID:
    31706099
    [PubMed - as supplied by publisher]
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The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity.
Canon J, Rex K, Saiki AY, Mohr C, Cooke K, Bagal D, Gaida K, Holt T, Knutson CG, Koppada N, Lanman BA, Werner J, Rapaport AS, San Miguel T, Ortiz R, Osgood T, Sun JR, Zhu X, McCarter JD, Volak LP, Houk BE, Fakih MG, O'Neil BH, Price TJ, Falchook GS, Desai J, Kuo J, Govindan R, Hong DS, Ouyang W, Henary H, Arvedson T, Cee VJ, Lipford JR
Nature. 2019 Nov; 575(7781)217-223. doi: 10.1038/s41586-019-1694-1.

PMID:
    31666701
    [PubMed - in process]
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Open-Sourced CIViC Annotation Pipeline to Identify and Annotate Clinically Relevant Variants Using Single-Molecule Molecular Inversion Probes.
Barnell EK, Waalkes A, Mosior MC, Penewit K, Cotto KC, Danos AM, Sheta LM, Campbell KM, Krysiak K, Rieke D, Spies NC, Skidmore ZL, Pritchard CC, Fehniger TA, Uppaluri R, Govindan R, Griffith M, Salipante SJ, Griffith OL
JCO Clin Cancer Inform. 2019 Oct; 31-12. doi: 10.1200/CCI.19.00077.

PMID:
    31618044
    [PubMed - in process]
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Efficacy and Safety of Rovalpituzumab Tesirine in Third-Line and Beyond Patients with DLL3-Expressing, Relapsed/Refractory Small-Cell Lung Cancer: Results From the Phase II TRINITY Study.
Morgensztern D, Besse B, Greillier L, Santana-Davila R, Ready N, Hann CL, Glisson BS, Farago AF, Dowlati A, Rudin CM, Moulec SL, Lally S, Yalamanchili S, Wolf J, Govindan R, Carbone DP
Clin Cancer Res. 2019 Sep 10; doi: 10.1158/1078-0432.CCR-19-1133.

PMID:
    31506387
    [PubMed - as supplied by publisher]
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Identifying an optimal epoch length for spectral analysis of heart rate of critically-ill infants.
Govindan RB, Massaro A, Vezina G, Chang T, du Plessis A
Comput Biol Med. 2019 Oct; 113103391. doi: 10.1016/j.compbiomed.2019.103391.

PMID:
    31446320
    [PubMed - in process]
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The Immune Landscape of Cancer.
Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS, Cancer Genome Atlas Research Network., Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I
Immunity. 2019 Aug 20; 51(2)411-412. doi: 10.1016/j.immuni.2019.08.004.

PMID:
    31433971
    [PubMed]
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The effect of labor and delivery mode on electrocortical and brainstem autonomic function during neonatal transition.
Mulkey SB, Kota S, Govindan RB, Al-Shargabi T, Swisher CB, Eze A Jr, Hitchings L, Russo S, Herrera N, McCarter R, Maxwell GL, Baker R, du Plessis AJ
Sci Rep. 2019 Jul 30; 9(1)11020. doi: 10.1038/s41598-019-47306-1.

PMID:
    31363124
    [PubMed - in process]
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Circulating Tumor DNA Profiling in Small-Cell Lung Cancer Identifies Potentially Targetable Alterations.
Devarakonda S, Sankararaman S, Herzog BH, Gold KA, Waqar SN, Ward JP, Raymond VM, Lanman RB, Chaudhuri AA, Owonikoko TK, Li BT, Poirier JT, Rudin CM, Govindan R, Morgensztern D
Clin Cancer Res. 2019 Oct 15; 25(20)6119-6126. doi: 10.1158/1078-0432.CCR-19-0879.

PMID:
    31300452
    [PubMed - in process]
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Untangling the evolutionary roots of lung cancer.
Devarakonda S, Govindan R
Nat Commun. 2019 Jul 5; 10(1)2979. doi: 10.1038/s41467-019-10879-6.

PMID:
    31278259
    [PubMed - indexed for MEDLINE]
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Phase I, Open-Label, Dose-Escalation Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of GSK2879552 in Relapsed/Refractory SCLC.
Bauer TM, Besse B, Martinez-Marti A, Trigo JM, Moreno V, Garrido P, Ferron-Brady G, Wu Y, Park J, Collingwood T, Kruger RG, Mohammad HP, Ballas MS, Dhar A, Govindan R
J Thorac Oncol. 2019 Oct; 14(10)1828-1838. doi: 10.1016/j.jtho.2019.06.021.

PMID:
    31260835
    [PubMed - in process]
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Heart rate variability is depressed in the early transitional period for newborns with complex congenital heart disease.
Mulkey SB, Govindan R, Metzler M, Swisher CB, Hitchings L, Wang Y, Baker R, Larry Maxwell G, Krishnan A, du Plessis AJ
Clin Auton Res. 2019 Jun 25; doi: 10.1007/s10286-019-00616-w.

PMID:
    31240423
    [PubMed - as supplied by publisher]
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Healthcare resource utilization and associated cost analysis of the PROCLAIM study in patients with stage III non-small-cell lung cancer.
Govindan R, Senan S, Dickgreber N, Provencio M, Wu YL, Syrigos K, Parente B, Wilson M, Ziemiecki R, Chouaki N, Hossain A, San Antonio B, Winfree K, Vokes EE
Curr Med Res Opin. 2019 Oct; 35(10)1761-1767. doi: 10.1080/03007995.2019.1623185.

PMID:
    31125266
    [PubMed - in process]
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Multicenter Phase I Study of Erdafitinib (JNJ-42756493), Oral Pan-Fibroblast Growth Factor Receptor Inhibitor, in Patients with Advanced or Refractory Solid Tumors.
Bahleda R, Italiano A, Hierro C, Mita A, Cervantes A, Chan N, Awad M, Calvo E, Moreno V, Govindan R, Spira A, Gonzalez M, Zhong B, Santiago-Walker A, Poggesi I, Parekh T, Xie H, Infante J, Tabernero J
Clin Cancer Res. 2019 Aug 15; 25(16)4888-4897. doi: 10.1158/1078-0432.CCR-18-3334.

PMID:
    31088831
    [PubMed - in process]
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Knowledge and perceptions of Indian primary care nurses towards mental illness.
Gandhi S, Poreddi V, Govindan R, G J, Anjanappa S, Sahu M, Narayanasamy P, N M, C N, Badamath S
Invest Educ Enferm. 2019 Feb; 37(1)doi: 10.17533/udea.iee.v37n1e06.

PMID:
    31083843
    [PubMed - in process]
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Comparison of Frequency- and Time-Domain Autoregulation and Vasoreactivity Indices in a Piglet Model of Hypoxia-Ischemia and Hypothermia.
Govindan RB, Brady KM, Massaro AN, Perin J, Jennings JM, DuPlessis AJ, Koehler RC, Lee JK
Dev Neurosci. 2019 May 2; 1-13. doi: 10.1159/000499425.

PMID:
    31048593
    [PubMed - as supplied by publisher]
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The effect of unilateral stroke on autonomic function in the term newborn.
Reich DA, Govindan RB, Whitehead MT, Wang J, Chang T, Kota S, du Plessis AJ
Pediatr Res. 2019 May; 85(6)830-834. doi: 10.1038/s41390-019-0320-0.

PMID:
    30712058
    [PubMed - in process]
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Anodal tDCS modulates cortical activity and synchronization in Parkinson's disease depending on motor processing.
Schoellmann A, Scholten M, Wasserka B, Govindan RB, Krüger R, Gharabaghi A, Plewnia C, Weiss D
Neuroimage Clin. 2019; 22101689. doi: 10.1016/j.nicl.2019.101689.

PMID:
    30708350
    [PubMed - in process]
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Phase II Study of Roniciclib in Combination with Cisplatin/Etoposide or Carboplatin/Etoposide as First-Line Therapy in Patients with Extensive-Disease Small Cell Lung Cancer.
Reck M, Horn L, Novello S, Barlesi F, Albert I, Juhász E, Kowalski D, Robinet G, Cadranel J, Bidoli P, Chung J, Fritsch A, Drews U, Wagner A, Govindan R
J Thorac Oncol. 2019 Apr; 14(4)701-711. doi: 10.1016/j.jtho.2019.01.010.

PMID:
    30677506
    [PubMed - in process]
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Accounting for proximal variants improves neoantigen prediction.
Hundal J, Kiwala S, Feng YY, Liu CJ, Govindan R, Chapman WC, Uppaluri R, Swamidass SJ, Griffith OL, Mardis ER, Griffith M
Nat Genet. 2019 Jan; 51(1)175-179. doi: 10.1038/s41588-018-0283-9.

PMID:
    30510237
    [PubMed - indexed for MEDLINE]
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SELECT: A Phase II Trial of Adjuvant Erlotinib in Patients With Resected Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer.
Pennell NA, Neal JW, Chaft JE, Azzoli CG, Jänne PA, Govindan R, Evans TL, Costa DB, Wakelee HA, Heist RS, Shapiro MA, Muzikansky A, Murthy S, Lanuti M, Rusch VW, Kris MG, Sequist LV
J Clin Oncol. 2019 Jan 10; 37(2)97-104. doi: 10.1200/JCO.18.00131.

PMID:
    30444685
    [PubMed - indexed for MEDLINE]
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