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Rajendra S. Apte, MD, PhD

Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences

Specialty Areas

Ophthalmology, Retina
Retina
Ophthalmology

Board Certifications

Ophthalmology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Diabetic retinopathy, macular surgery, macular holes, macular pucker, age-related macular degeneration, vitreous substitutes, retinal detachments

  • Maps & Directions
  • Education
  • Publication & Research
  • In the News
  • Financial Disclosures
  • Videos

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Eye Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 12
Office Phone: 314-362-EYES
Fax: 314-362-3725

Center for Advanced Medicine - South County

5201 Midamerica Plaza
St. Louis, MO 63129

Office Phone: 314-273-0020
Fax: 314-842-2316

Education

Education

Fellowship: Vitreoretinal, Wilmer Ophthalmological Institute, Baltimore, Maryland 2003
Fellowship: Retinal Vascular, Wilmer Ophthalmological Institute, Baltimore, Maryland 2002
Residency: Ophthalmology, UT Southwestern Medical Center, Dallas, Texas 2001
Ph.D.: Cellular and Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 1997
Medical Degree: L.T.M. Medical College, University of Bombay, Bombay, India 1992
Pre-Med: University of Bombay, Bombay, India 1986

Publication & Research

Publication & Research

Impaired autophagy in macrophages promotes inflammatory eye disease.
Santeford A, Wiley LA, Park S, Bamba S, Nakamura R, Gdoura A, Ferguson TA, Rao PK, Guan JL, Saitoh T, Akira S, Xavier R, Virgin Iv HW, Apte RS
Autophagy. 2016 Jul 27; 1-10.

PMID:
    27463423
    [PubMed - as supplied by publisher]
Related citations


Physician-Industry Interactions and Anti-Vascular Endothelial Growth Factor Use Among US Ophthalmologists.
Taylor SC, Huecker JB, Gordon MO, Vollman DE, Apte RS
JAMA Ophthalmol. 2016 Aug 1; 134(8)897-903. doi: 10.1001/jamaophthalmol.2016.1678.

PMID:
    27356110
    [PubMed - in process]
Related citations


Targeting Tissue Lipids in Age-related Macular Degeneration.
Apte RS
EBioMedicine. 2016 Mar; 526-7. doi: 10.1016/j.ebiom.2016.02.003.

PMID:
    27077107
    [PubMed - indexed for MEDLINE]
Related citations


Combined Epiretinal and Internal Limiting Membrane Peeling Facilitated by High Dilution Indocyanine Green Negative Staining.
Kaehr MM, Apte RS
J Ophthalmic Vis Res. 2015 Oct-Dec; 10(4)495-7. doi: 10.4103/2008-322X.176898.

PMID:
    27051499
    [PubMed]
Related citations


Dissociations of the Fluocinolone Acetonide Implant: The Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study.
Holbrook JT, Sugar EA, Burke AE, Vitale AT, Thorne JE, Davis JL, Jabs DA, Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group
Am J Ophthalmol. 2016 Apr; 16429-36. doi: 10.1016/j.ajo.2015.12.028.

PMID:
    26748056
    [PubMed - in process]
Related citations


What Is Chronic or Persistent Diabetic Macular Edema and How Should It Be Treated?
Apte RS
JAMA Ophthalmol. 2016 Mar; 134(3)285-6. doi: 10.1001/jamaophthalmol.2015.5469.

PMID:
    26746003
    [PubMed - indexed for MEDLINE]
Related citations


Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2.
Park C, Lee TJ, Bhang SH, Liu F, Nakamura R, Oladipupo SS, Pitha-Rowe I, Capoccia B, Choi HS, Kim TM, Urao N, Ushio-Fukai M, Lee D, Miyoshi H, Kim BS, Lim DS, Apte RS, Ornitz DM, Choi K
Arterioscler Thromb Vasc Biol. 2016 Jan; 36(1)86-96. doi: 10.1161/ATVBAHA.115.306430.

PMID:
    26586661
    [PubMed - indexed for MEDLINE]
Related citations


Seeing through thick and through thin: Retinal manifestations of thrombophilic and hyperviscosity syndromes.
Rajagopal R, Apte RS
Surv Ophthalmol. 2016 Mar-Apr; 61(2)236-47. doi: 10.1016/j.survophthal.2015.10.006.

PMID:
    26519860
    [PubMed - in process]
Related citations


A systematic review of as needed versus treat and extend ranibizumab or bevacizumab treatment regimens for neovascular age-related macular degeneration.
Chin-Yee D, Eck T, Fowler S, Hardi A, Apte RS
Br J Ophthalmol. 2015 Oct 29; pii: bjophthalmol-2015-306987. doi: 10.1136/bjophthalmol-2015-306987.

PMID:
    26516125
    [PubMed - as supplied by publisher]
Related citations


SCLERAL BUCKLING WITH WIDE-ANGLED ENDOILLUMINATION AS A SURGICAL EDUCATIONAL TOOL.
Narayanan R, Tyagi M, Hussein A, Chhablani J, Apte RS
Retina. 2016 Apr; 36(4)830-3. doi: 10.1097/IAE.0000000000000792.

PMID:
    26447399
    [PubMed - in process]
Related citations


Factors Predicting Visual Acuity Outcome in Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial.
Kempen JH, Van Natta ML, Altaweel MM, Dunn JP, Jabs DA, Lightman SL, Thorne JE, Holbrook JT, Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group
Am J Ophthalmol. 2015 Dec; 160(6)1133-1141.e9. doi: 10.1016/j.ajo.2015.09.017.

PMID:
    26386159
    [PubMed - indexed for MEDLINE]
Related citations


Outcome of Treatment of Uveitic Macular Edema: The Multicenter Uveitis Steroid Treatment Trial 2-Year Results.
Tomkins-Netzer O, Lightman S, Drye L, Kempen J, Holland GN, Rao NA, Stawell RJ, Vitale A, Jabs DA, Multicenter Uveitis Steroid Treatment Trial Research Group
Ophthalmology. 2015 Nov; 122(11)2351-9. doi: 10.1016/j.ophtha.2015.07.036.

PMID:
    26359188
    [PubMed - indexed for MEDLINE]
Related citations


Quality of Life and Risks Associated with Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, or Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatment Trial and Follow-up Study.
Multicenter Uveitis Steroid Treatment (MUST) Trial Follow-up Study Research Group
Ophthalmology. 2015 Oct; 122(10)1976-86. doi: 10.1016/j.ophtha.2015.06.043.

PMID:
    26298718
    [PubMed - indexed for MEDLINE]
Related citations


Benefits of Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, and Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study.
Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group, Kempen JH, Altaweel MM, Drye LT, Holbrook JT, Jabs DA, Sugar EA, Thorne JE
Ophthalmology. 2015 Oct; 122(10)1967-75. doi: 10.1016/j.ophtha.2015.06.042.

PMID:
    26298715
    [PubMed - indexed for MEDLINE]
Related citations


IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis.
Nakamura R, Sene A, Santeford A, Gdoura A, Kubota S, Zapata N, Apte RS
Nat Commun. 2015 Aug 11; 67847. doi: 10.1038/ncomms8847.

PMID:
    26260587
    [PubMed - indexed for MEDLINE]
Related citations


Microstructural retinal findings by spectral-domain optical coherence tomography after vitrectomy repair of rhegmatogenous retinal detachments.
Kumar GN, Rao PK, Apte RS
Ophthalmic Surg Lasers Imaging Retina. 2015 Apr; 46(4)493-8. doi: 10.3928/23258160-20150422-17.

PMID:
    25932731
    [PubMed - indexed for MEDLINE]
Related citations


Full thickness macular hole case after intravitreal aflibercept treatment.
Oshima Y, Apte RS, Nakao S, Yoshida S, Ishibashi T
BMC Ophthalmol. 2015 Mar 29; 1530. doi: 10.1186/s12886-015-0021-3.

PMID:
    25881212
    [PubMed - indexed for MEDLINE]
Related citations


Autophagy supports survival and phototransduction protein levels in rod photoreceptors.
Zhou Z, Doggett TA, Sene A, Apte RS, Ferguson TA
Cell Death Differ. 2015 Mar; 22(3)488-98. doi: 10.1038/cdd.2014.229.

PMID:
    25571975
    [PubMed - indexed for MEDLINE]
Related citations


Seeing through VEGF: innate and adaptive immunity in pathological angiogenesis in the eye.
Sene A, Chin-Yee D, Apte RS
Trends Mol Med. 2015 Jan; 21(1)43-51. doi: 10.1016/j.molmed.2014.10.005.

PMID:
    25457617
    [PubMed - indexed for MEDLINE]
Related citations


Endothelial cell FGF signaling is required for injury response but not for vascular homeostasis.
Oladipupo SS, Smith C, Santeford A, Park C, Sene A, Wiley LA, Osei-Owusu P, Hsu J, Zapata N, Liu F, Nakamura R, Lavine KJ, Blumer KJ, Choi K, Apte RS, Ornitz DM
Proc Natl Acad Sci U S A. 2014 Sep 16; 111(37)13379-84. doi: 10.1073/pnas.1324235111.

PMID:
    25139991
    [PubMed - indexed for MEDLINE]
Related citations

In the News

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2015.

Company Name: Liberty Biosecurity

Royalties:

Equity: Yes

Consulting/Advisory Board:

Speaker Fees:

Reporting Date: May 01, 2016


Company Name: Metro Midwest Biotech

Royalties:

Equity: Yes

Consulting/Advisory Board:

Speaker Fees:

Reporting Date: May 01, 2016


Company Name: Ophthotech

Royalties:

Equity: Yes

Consulting/Advisory Board:

Speaker Fees:

Reporting Date: May 01, 2016

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