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Faculty Physicians

Rajendra S. Apte, MD, PhD

Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences

Specialty Areas

Ophthalmology, Retina
Retina
Ophthalmology

Board Certifications

Ophthalmology

Areas of Clinical Interest

Diabetic retinopathy, macular surgery, macular holes, macular pucker, age-related macular degeneration, vitreous substitutes, retinal detachments

  • Maps & Directions
  • Education
  • Publication & Research
  • Financial Disclosures

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Eye Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 12
Office Phone: 314-362-EYES
Fax: 314-362-3725

Washington University Eye Center in South County

13303 Tesson Ferry Road
St. Louis , MO 63128

Office Phone: 314-273-0020
Fax: 314-842-2316

Education

Education

Fellowship: Vitreoretinal, Wilmer Ophthalmological Institute, Baltimore, Maryland 2003
Fellowship: Retinal Vascular, Wilmer Ophthalmological Institute, Baltimore, Maryland 2002
Residency: Ophthalmology, UT Southwestern Medical Center, Dallas, Texas 2001
Ph.D.: Cellular and Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 1997
Medical Degree: L.T.M. Medical College, University of Bombay, Bombay, India 1992
Pre-Med: University of Bombay, Bombay, India 1986

Publication & Research

Publication & Research

Visual cycle suppression via patching in central serous chorioretinopathy.
Earl JB, Lee CS, Yom V, Van Stavern GP, Abuattieh M, Chin-Yee D, Rao PK, Apte RS
Ophthalmology. 2014 Dec; 121(12)2502-4.e1. doi: 10.1016/j.ophtha.2014.06.038.

PMID:
    25109933
    [PubMed - indexed for MEDLINE]
Related citations


Cost-effectiveness of fluocinolone acetonide implant versus systemic therapy for noninfectious intermediate, posterior, and panuveitis.
Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group, Sugar EA, Holbrook JT, Kempen JH, Burke AE, Drye LT, Thorne JE, Louis TA, Jabs DA, Altaweel MM, Frick KD
Ophthalmology. 2014 Oct; 121(10)1855-62. doi: 10.1016/j.ophtha.2014.04.022.

PMID:
    24908205
    [PubMed - indexed for MEDLINE]
Related citations


Subconjunctival bevacizumab for iris neovascularisation - Authors' reply.
Rao RC, Choudhry N, Apte RS
Lancet Diabetes Endocrinol. 2014 Jun; 2(6)450-1. doi: 10.1016/S2213-8587(14)70071-3.

PMID:
    24880562
    [PubMed - indexed for MEDLINE]
Related citations


Regression of iris neovascularisation secondary to diabetic retinopathy with subconjunctival anti-VEGF therapy.
Rao RC, Choudhry N, Apte RS
Lancet Diabetes Endocrinol. 2014 Feb; 2(2)182. doi: 10.1016/S2213-8587(13)70150-5.

PMID:
    24622722
    [PubMed - indexed for MEDLINE]
Related citations


Eyeballing cholesterol efflux and macrophage function in disease pathogenesis.
Sene A, Apte RS
Trends Endocrinol Metab. 2014 Mar; 25(3)107-14. doi: 10.1016/j.tem.2013.10.007.

PMID:
    24252662
    [PubMed - indexed for MEDLINE]
Related citations


Fluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edema.
Kempen JH, Sugar EA, Jaffe GJ, Acharya NR, Dunn JP, Elner SG, Lightman SL, Thorne JE, Vitale AT, Altaweel MM, Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group
Ophthalmology. 2013 Sep; 120(9)1852-9. doi: 10.1016/j.ophtha.2013.01.069.

PMID:
    23706700
    [PubMed - indexed for MEDLINE]
Related citations


Risk of elevated intraocular pressure and glaucoma in patients with uveitis: results of the multicenter uveitis steroid treatment trial.
Friedman DS, Holbrook JT, Ansari H, Alexander J, Burke A, Reed SB, Katz J, Thorne JE, Lightman SL, Kempen JH, MUST Research Group
Ophthalmology. 2013 Aug; 120(8)1571-9. doi: 10.1016/j.ophtha.2013.01.025.

PMID:
    23601801
    [PubMed - indexed for MEDLINE]
Related citations


Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration.
Sene A, Khan AA, Cox D, Nakamura RE, Santeford A, Kim BM, Sidhu R, Onken MD, Harbour JW, Hagbi-Levi S, Chowers I, Edwards PA, Baldan A, Parks JS, Ory DS, Apte RS
Cell Metab. 2013 Apr 2; 17(4)549-61. doi: 10.1016/j.cmet.2013.03.009.

PMID:
    23562078
    [PubMed - indexed for MEDLINE]
Related citations


Cost-effectiveness analysis of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema.
Dewan V, Lambert D, Edler J, Kymes S, Apte RS
Ophthalmology. 2012 Aug; 119(8)1679-84. doi: 10.1016/j.ophtha.2012.01.049.

PMID:
    22503301
    [PubMed - indexed for MEDLINE]
Related citations


Hypotony in patients with uveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial.
Sen HN, Drye LT, Goldstein DA, Larson TA, Merrill PT, Pavan PR, Sheppard JD, Burke A, Srivastava SK, Jabs DA, Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group
Ocul Immunol Inflamm. 2012 Apr; 20(2)104-12. doi: 10.3109/09273948.2011.647228.

PMID:
    22409563
    [PubMed - indexed for MEDLINE]
Related citations


Evaluation of visual acuity measurements after autorefraction vs manual refraction in eyes with and without diabetic macular edema.
Sun JK, Qin H, Aiello LP, Melia M, Beck RW, Andreoli CM, Edwards PA, Glassman AR, Pavlica MR, Diabetic Retinopathy Clinical Research Network
Arch Ophthalmol. 2012 Apr; 130(4)470-9. doi: 10.1001/archophthalmol.2011.377.

PMID:
    22159173
    [PubMed - indexed for MEDLINE]
Related citations


Morphologic assessment for glaucoma in the Multicenter Uveitis Steroid Treatment (MUST) trial.
Gangaputra SS, Altaweel MM, Peng Q, Friedman DS, Rao PK, Foster CS, Kim RY, Reed SB, Srivastava SK, Wong IG, Kempen JH, MUST Trial Research Group
Ocul Immunol Inflamm. 2011 Aug; 19(4)267-74. doi: 10.3109/09273948.2011.583376.

PMID:
    21770805
    [PubMed - indexed for MEDLINE]
Related citations


Effect of preoperative vitreous status on visual outcomes following vitrectomy for epiretinal membrane repair.
Kraus CL, Rao PK, Apte RS
Can J Ophthalmol. 2011 Apr; 46(2)186-90. doi: 10.3129/i10-100.

PMID:
    21708089
    [PubMed - indexed for MEDLINE]
Related citations


Comparison of film and digital fundus photographs in eyes of individuals with diabetes mellitus.
Gangaputra S, Almukhtar T, Glassman AR, Aiello LP, Bressler N, Bressler SB, Danis RP, Davis MD, Diabetic Retinopathy Clinical Research Network
Invest Ophthalmol Vis Sci. 2011 Aug 3; 52(9)6168-73. doi: 10.1167/iovs.11-7321.

PMID:
    21571677
    [PubMed - indexed for MEDLINE]
Related citations


Pattern electroretinography in age-related macular degeneration.
Sheybani A, Brantley MA Jr, Apte RS
Arch Ophthalmol. 2011 May; 129(5)580-4. doi: 10.1001/archophthalmol.2011.83.

PMID:
    21555610
    [PubMed - indexed for MEDLINE]
Related citations


N-acetylcysteine amide (NACA) prevents retinal degeneration by up-regulating reduced glutathione production and reversing lipid peroxidation.
Schimel AM, Abraham L, Cox D, Sene A, Kraus C, Dace DS, Ercal N, Apte RS
Am J Pathol. 2011 May; 178(5)2032-43. doi: 10.1016/j.ajpath.2011.01.036.

PMID:
    21457933
    [PubMed - indexed for MEDLINE]
Related citations


An observational retrospective subgroup analysis of verteporfin photodynamic therapy-naive and previously treated patients in the focus trial.
Apte RS, Alexander SL, Henry EC, Wong P, Tuomi L
Retina. 2011 Jan; 31(1)56-64. doi: 10.1097/IAE.0b013e3181e09720.

PMID:
    20890244
    [PubMed - indexed for MEDLINE]
Related citations


Full-thickness macular hole in a patient with proliferative sickle cell retinopathy.
Rajagopal R, Apte RS
Retina. 2010 May; 30(5)838-9. doi: 10.1097/IAE.0b013e3181d87ee7.

PMID:
    20453806
    [PubMed - indexed for MEDLINE]
Related citations


Vitrectomy outcomes in eyes with diabetic macular edema and vitreomacular traction.
Diabetic Retinopathy Clinical Research Network Writing Committee, Haller JA, Qin H, Apte RS, Beck RR, Bressler NM, Browning DJ, Danis RP, Glassman AR, Googe JM, Kollman C, Lauer AK, Peters MA, Stockman ME
Ophthalmology. 2010 Jun; 117(6)1087-1093.e3. doi: 10.1016/j.ophtha.2009.10.040.

PMID:
    20299105
    [PubMed - indexed for MEDLINE]
Related citations


Regulation of angiogenesis by macrophages.
Apte RS
Adv Exp Med Biol. 2010; 66415-9. doi: 10.1007/978-1-4419-1399-9_2.

PMID:
    20237997
    [PubMed - indexed for MEDLINE]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2014.

Company Name: Genentech

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $10,001 - $25,000

Reporting Date: May 01, 2015


Company Name: Opthlotech

Royalties:

Equity: Yes

Consulting/Advisory Board:

Speaker Fees:

Reporting Date: May 01, 2015