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Premal H. Thaker, MD, MS

Associate Professor, Obstetrics and Gynecology
Division of Gynecologic Oncology

Specialty Areas

Cervical Cancer
Gynecologic Oncology
Ovarian Cancer
Endometrial Cancer

Board Certifications

Gynecologic Oncology
Obstetrics and Gynecology

Hospital Affiliations

Barnes-Jewish Hospital
Missouri Baptist Medical Center
Progress West Hospital

Areas of Clinical Interest

Gynecologic oncology, endometrial cancer, vulvar carcinoma, cervical cancer, ovarian cancer, adnexal masses, tumors, hysterectomy, ob/gyn, women's health, lymphadenectomy, endometrial adenocarcinomas, cervical intraepithelial neoplasia, laparoscopy, gynecologic malignancies

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Missouri Baptist Medical Center
Building D

3023 N. Ballas Road
Fourth Floor, Suite 450
St. Louis, MO 63131

Suite: Suite 450
Office Phone: 314-996-6075
Fax: 314-996-6074

Center for Advanced Medicine
Gynecologic Treatment Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 13
Office Phone: 314-362-3181
Fax: 314-362-8644

Education

Education

Fellowship: Gynecologic Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 2006
Residency: Obstetrics and Gynecolgy, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 2002
M.S.: Cancer Biology, University of Texas Graduate School of Biomedical Sciences, Houston, Texas 2004
Medical Degree: Allegheny University-Medical College of PA, Philadelphia, Pennsylvania 1997
B.A.: Biology, Villanova University, Villanova, Pennsylvania 1995

Publication & Research

Publication & Research

A rare case of endometrial cancer metastatic to the uveal choroid.
Smith SH, Arudra SKC, Mullen MM, Palisoul M, Dahiya S, Kumar Rao P, Thaker PH
Gynecol Oncol Rep. 2018 Feb; 2324-27. doi: 10.1016/j.gore.2018.01.001.

PMID:
    29326973
    [PubMed]
Related citations


Biobehavioral modulation of the exosome transcriptome in ovarian carcinoma.
Lutgendorf SK, Thaker PH, Arevalo JM, Goodheart MJ, Slavich GM, Sood AK, Cole SW
Cancer. 2017 Nov 7; doi: 10.1002/cncr.31078.

PMID:
    29112229
    [PubMed - as supplied by publisher]
Related citations


Endometrial carcinoma recurrence according to race and ethnicity: An NRG Oncology/Gynecologic Oncology Group 210 Study.
Felix AS, Brasky TM, Cohn DE, Mutch DG, Creasman WT, Thaker PH, Walker JL, Moore RG, Lele SB, Guntupalli SR, Downs LS, Nagel C, Boggess JF, Pearl ML, Ioffe OB, Deng W, Miller DS, Brinton LA
Int J Cancer. 2017 Oct 24; doi: 10.1002/ijc.31127.

PMID:
    29063589
    [PubMed - as supplied by publisher]
Related citations


Benefit of combination chemotherapy and radiation stratified by grade of stage IIIC endometrial cancer.
Binder PS, Kuroki LM, Zhao P, Cusworth S, Divine LM, Hagemann AR, McCourt CK, Thaker PH, Powell MA, Mutch DG, Massad LS
Gynecol Oncol. 2017 Nov; 147(2)309-314. doi: 10.1016/j.ygyno.2017.08.031.

PMID:
    28916118
    [PubMed - indexed for MEDLINE]
Related citations


Inhibition of the Receptor Tyrosine Kinase AXL Restores Paclitaxel Chemosensitivity in Uterine Serous Cancer.
Palisoul ML, Quinn JM, Schepers E, Hagemann IS, Guo L, Reger K, Hagemann AR, McCourt CK, Thaker PH, Powell MA, Mutch DG, Fuh KC
Mol Cancer Ther. 2017 Dec; 16(12)2881-2891. doi: 10.1158/1535-7163.MCT-17-0587.

PMID:
    28904132
    [PubMed - in process]
Related citations


A phase I trial of intraperitoneal GEN-1, an IL-12 plasmid formulated with PEG-PEI-cholesterol lipopolymer, administered with pegylated liposomal doxorubicin in patients with recurrent or persistent epithelial ovarian, fallopian tube or primary peritoneal cancers: An NRG Oncology/Gynecologic Oncology Group study.
Thaker PH, Brady WE, Lankes HA, Odunsi K, Bradley WH, Moore KN, Muller CY, Anwer K, Schilder RJ, Alvarez RD, Fracasso PM
Gynecol Oncol. 2017 Nov; 147(2)283-290. doi: 10.1016/j.ygyno.2017.08.001.

PMID:
    28802766
    [PubMed - indexed for MEDLINE]
Related citations


The effect of a multidisciplinary palliative care initiative on end of life care in gynecologic oncology patients.
Mullen MM, Divine LM, Porcelli BP, Wilkinson-Ryan I, Dans MC, Powell MA, Mutch DG, Hagemann AR, Thaker PH
Gynecol Oncol. 2017 Nov; 147(2)460-464. doi: 10.1016/j.ygyno.2017.08.002.

PMID:
    28784245
    [PubMed - indexed for MEDLINE]
Related citations


Diurnal cortisol rhythms, fatigue and psychosocial factors in five-year survivors of ovarian cancer.
Cuneo MG, Schrepf A, Slavich GM, Thaker PH, Goodheart M, Bender D, Cole SW, Sood AK, Lutgendorf SK
Psychoneuroendocrinology. 2017 Oct; 84139-142. doi: 10.1016/j.psyneuen.2017.06.019.

PMID:
    28711723
    [PubMed - in process]
Related citations


Risk of Subsequent Ovarian Cancer After Ovarian Conservation in Young Women With Stage I Endometrioid Endometrial Cancer.
Matsuo K, Machida H, Stone RL, Soliman PT, Thaker PH, Roman LD, Wright JD
Obstet Gynecol. 2017 Aug; 130(2)403-410. doi: 10.1097/AOG.0000000000002142.

PMID:
    28697110
    [PubMed - indexed for MEDLINE]
Related citations


Yield of Cytology Surveillance After High-Grade Vulvar Intraepithelial Neoplasia or Cancer.
Kuroki LM, Frolova AI, Wu N, Liu J, Powell M, Thaker PH, Massad LS
J Low Genit Tract Dis. 2017 Jul; 21(3)193-197. doi: 10.1097/LGT.0000000000000321.

PMID:
    28644191
    [PubMed - in process]
Related citations


Changes in spiritual well-being and psychological outcomes in ovarian cancer survivors.
Davis LZ, Cuneo M, Thaker PH, Goodheart MJ, Bender D, Lutgendorf SK
Psychooncology. 2017 Jun 21; doi: 10.1002/pon.4485.

PMID:
    28637083
    [PubMed - as supplied by publisher]
Related citations


Restraint and Social Isolation Stressors Differentially Regulate Adaptive Immunity and Tumor Angiogenesis in a Breast Cancer Mouse Model.
Budiu RA, Vlad AM, Nazario L, Bathula C, Cooper KL, Edmed J, Thaker PH, Urban J, Kalinski P, Lee AV, Elishaev EL, Conrads TP, Flint MS
Cancer Clin Oncol. 2017 May; 6(1)12-24. doi: 10.5539/cco.v6n1p12.

PMID:
    28603578
    [PubMed]
Related citations


Wound Complication Rates After Staples or Suture for Midline Vertical Skin Closure in Obese Women: A Randomized Controlled Trial.
Kuroki LM, Mullen MM, Massad LS, Wu N, Liu J, Mutch DG, Powell MA, Hagemann AR, Thaker PH, McCourt CK, Novetsky AP
Obstet Gynecol. 2017 Jul; 130(1)91-99. doi: 10.1097/AOG.0000000000002061.

PMID:
    28594761
    [PubMed - indexed for MEDLINE]
Related citations


Identification of molecular targets in vulvar cancers.
Palisoul ML, Mullen MM, Feldman R, Thaker PH
Gynecol Oncol. 2017 Aug; 146(2)305-313. doi: 10.1016/j.ygyno.2017.05.011.

PMID:
    28536037
    [PubMed - indexed for MEDLINE]
Related citations


Survival of Cervical Cancer Patients Presenting with Occult Supraclavicular Metastases Detected by FDG-Positron Emission Tomography/CT: Impact of Disease Extent and Treatment.
Ioffe YJ, Massad LS, Powell MA, Hagemann AR, Mutch DG, Thaker PH, Schwarz JK, Grigsby PW
Gynecol Obstet Invest. 2017 Apr 8; doi: 10.1159/000458706.

PMID:
    28399524
    [PubMed - as supplied by publisher]
Related citations


Nonsteroidal Anti-inflammatory Drugs and Endometrial Carcinoma Mortality and Recurrence.
Brasky TM, Felix AS, Cohn DE, McMeekin DS, Mutch DG, Creasman WT, Thaker PH, Walker JL, Moore RG, Lele SB, Guntupalli SR, Downs LS, Nagel CI, Boggess JF, Pearl ML, Ioffe OB, Park KJ, Ali S, Brinton LA
J Natl Cancer Inst. 2017 Mar 1; 109(3)1-10. doi: 10.1093/jnci/djw251.

PMID:
    28376204
    [PubMed - indexed for MEDLINE]
Related citations


A stratified randomized double-blind phase II trial of celecoxib for treating patients with cervical intraepithelial neoplasia: The potential predictive value of VEGF serum levels: An NRG Oncology/Gynecologic Oncology Group study.
Rader JS, Sill MW, Beumer JH, Lankes HA, Benbrook DM, Garcia F, Trimble C, Tate Thigpen J, Lieberman R, Zuna RE, Leath CA 3rd, Spirtos NM, Byron J, Thaker PH, Lele S, Alberts D
Gynecol Oncol. 2017 May; 145(2)291-297. doi: 10.1016/j.ygyno.2017.02.040.

PMID:
    28285845
    [PubMed - indexed for MEDLINE]
Related citations


Nothing left to chance? The impact of locus of control on physical and mental quality of life in terminal cancer patients.
Brown AJ, Thaker PH, Sun CC, Urbauer DL, Bruera E, Bodurka DC, Ramondetta LM
Support Care Cancer. 2017 Jun; 25(6)1985-1991. doi: 10.1007/s00520-017-3605-z.

PMID:
    28175997
    [PubMed - indexed for MEDLINE]
Related citations


A phase I trial of paclitaxel, cisplatin, and veliparib in the treatment of persistent or recurrent carcinoma of the cervix: an NRG Oncology Study (NCT#01281852).
Thaker PH, Salani R, Brady WE, Lankes HA, Cohn DE, Mutch DG, Mannel RS, Bell-McGuinn KM, Di Silvestro PA, Jelovac D, Carter JS, Duan W, Resnick KE, Dizon DS, Aghajanian C, Fracasso PM
Ann Oncol. 2017 Mar 1; 28(3)505-511. doi: 10.1093/annonc/mdw635.

PMID:
    27998970
    [PubMed - indexed for MEDLINE]
Related citations


Stress and burnout among gynecologic oncologists: A Society of Gynecologic Oncology Evidence-based Review and Recommendations.
Cass I, Duska LR, Blank SV, Cheng G, duPont NC, Frederick PJ, Hill EK, Matthews CM, Pua TL, Rath KS, Ruskin R, Thaker PH, Berchuck A, Gostout BS, Kushner DM, Fowler JM
Gynecol Oncol. 2016 Nov; 143(2)421-427. doi: 10.1016/j.ygyno.2016.08.319.

PMID:
    27575910
    [PubMed - indexed for MEDLINE]
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