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Faculty Physicians

Phillip I. Tarr, MD

Melvin E. Carnahan Professor of Pediatrics
Director, Pediatric Division of Gastroenterolgy and Nutrition

Specialty Areas

Pediatric Gastroenterology

Board Certifications

Pediatrics
Pediatric Gastroenterology

Hospital Affiliations

St. Louis Children's Hospital

Areas of Clinical Interest

Gastrointestinal diseases, e coli, infectious diseases, nutrition, food safety

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Office Phone: 314-454-6173
Fax: 314-454-2412

Education

Education

Fellowship: Pediatric Gastroenterology, University of Washington School of Medicine and Children's Hosptial and Medical Center, Seattle, Washington 1989
Research Associate: Seattle Biomedical Intitute, Seattle, Washington 1987
Senior Fellow: Infectious Diseases, Department of Medicine, University of Washington School of Medicine, Seattle, Washington 1986
Residency: Pediatrics, University of Washington School of Medicine/Children's Orthopedic Hospital and Medical Center, Seattle, Washington 1983
Medical Degree: Yale University School of Medicine, New Haven, Connecticut 1980
A.B.: Biology, Brown University, Providence, Rhode Island 1975

Publication & Research

Publication & Research

Droplet digital PCR quantifies host inflammatory transcripts in feces reliably and reproducibly.
Stauber J, Shaikh N, Ordiz MI, Tarr PI, Manary MJ
Cell Immunol. 2016 Apr 6; pii: S0008-8749(16)30016-8. doi: 10.1016/j.cellimm.2016.03.007.

PMID:
    27063479
    [PubMed - as supplied by publisher]
Related citations


Environmental Enteric Dysfunction Includes a Broad Spectrum of Inflammatory Responses and Epithelial Repair Processes.
Yu J, Ordiz MI, Stauber J, Shaikh N, Trehan I, Barnell E, Head RD, Maleta K, Tarr PI, Manary MJ
Cell Mol Gastroenterol Hepatol. 2016 Feb; 2(2)158-174.e1.

PMID:
    26973864
    [PubMed]
Related citations


Gut bacteria dysbiosis and necrotising enterocolitis in very low birthweight infants: a prospective case-control study.
Warner BB, Deych E, Zhou Y, Hall-Moore C, Weinstock GM, Sodergren E, Shaikh N, Hoffmann JA, Linneman LA, Hamvas A, Khanna G, Rouggly-Nickless LC, Ndao IM, Shands BA, Escobedo M, Sullivan JE, Radmacher PG, Shannon WD, Tarr PI
Lancet. 2016 Mar 8; pii: S0140-6736(16)00081-7. doi: 10.1016/S0140-6736(16)00081-7.

PMID:
    26969089
    [PubMed - as supplied by publisher]
Related citations


Shiga Toxin-Producing Escherichia coli Infection, Antibiotics, and Risk of Developing Hemolytic Uremic Syndrome: A Meta-analysis.
Freedman SB, Xie J, Neufeld MS, Hamilton WL, Hartling L, Tarr PI, Alberta Provincial Pediatric Enteric Infection Team (APPETITE)
Clin Infect Dis. 2016 May 15; 62(10)1251-8. doi: 10.1093/cid/ciw099.

PMID:
    26917812
    [PubMed - in process]
Related citations


Early life dynamics of the human gut virome and bacterial microbiome in infants.
Lim ES, Zhou Y, Zhao G, Bauer IK, Droit L, Ndao IM, Warner BB, Tarr PI, Wang D, Holtz LR
Nat Med. 2015 Oct; 21(10)1228-34. doi: 10.1038/nm.3950.

PMID:
    26366711
    [PubMed - indexed for MEDLINE]
Related citations


The effect of dietary resistant starch type 2 on the microbiota and markers of gut inflammation in rural Malawi children.
Ordiz MI, May TD, Mihindukulasuriya K, Martin J, Crowley J, Tarr PI, Ryan K, Mortimer E, Gopalsamy G, Maleta K, Mitreva M, Young G, Manary MJ
Microbiome. 2015 Sep 3; 337. doi: 10.1186/s40168-015-0102-9.

PMID:
    26334878
    [PubMed - in process]
Related citations


Erratum: Gut resistome development in healthy twin pairs in the first year of life.
Moore AM, Ahmadi S, Patel S, Gibson MK, Wang B, Ndao IM, Deych E, Shannon W, Tarr PI, Warner BB, Dantas G
Microbiome. 2015; 329. doi: 10.1186/s40168-015-0095-4.

PMID:
    26207183
    [PubMed]
Related citations


Identification of Candidate Adherent-Invasive E. coli Signature Transcripts by Genomic/Transcriptomic Analysis.
Zhang Y, Rowehl L, Krumsiek JM, Orner EP, Shaikh N, Tarr PI, Sodergren E, Weinstock GM, Boedeker EC, Xiong X, Parkinson J, Frank DN, Li E, Gathungu G
PLoS One. 2015; 10(6)e0130902. doi: 10.1371/journal.pone.0130902.

PMID:
    26125937
    [PubMed - indexed for MEDLINE]
Related citations


Gut resistome development in healthy twin pairs in the first year of life.
Moore AM, Ahmadi S, Patel S, Gibson MK, Wang B, Ndao MI, Deych E, Shannon W, Tarr PI, Warner BB, Dantas G
Microbiome. 2015; 327. doi: 10.1186/s40168-015-0090-9.

PMID:
    26113976
    [PubMed]
Related citations


Impact of neonatal intensive care bed configuration on rates of late-onset bacterial sepsis and methicillin-resistant Staphylococcus aureus colonization.
Julian S, Burnham CA, Sellenriek P, Shannon WD, Hamvas A, Tarr PI, Warner BB
Infect Control Hosp Epidemiol. 2015 Oct; 36(10)1173-82. doi: 10.1017/ice.2015.144.

PMID:
    26108888
    [PubMed - in process]
Related citations


Gut Colonization of Healthy Children and Their Mothers With Pathogenic Ciprofloxacin-Resistant Escherichia coli.
Gurnee EA, Ndao IM, Johnson JR, Johnston BD, Gonzalez MD, Burnham CA, Hall-Moore CM, McGhee JE, Mellmann A, Warner BB, Tarr PI
J Infect Dis. 2015 Dec 15; 212(12)1862-8. doi: 10.1093/infdis/jiv278.

PMID:
    25969564
    [PubMed - indexed for MEDLINE]
Related citations


Real-Time PCR Assay for Detection and Differentiation of Shiga Toxin-Producing Escherichia coli from Clinical Samples.
Qin X, Klein EJ, Galanakis E, Thomas AA, Stapp JR, Rich S, Buccat AM, Tarr PI
J Clin Microbiol. 2015 Jul; 53(7)2148-53. doi: 10.1128/JCM.00115-15.

PMID:
    25926491
    [PubMed - indexed for MEDLINE]
Related citations


Agitation down-regulates immunoglobulin binding protein EibG expression in Shiga toxin-producing Escherichia coli (STEC).
Kuczius T, Zhang W, Merkel V, Mellmann A, Tarr PI, Karch H
PLoS One. 2015; 10(3)e0119583. doi: 10.1371/journal.pone.0119583.

PMID:
    25746924
    [PubMed - indexed for MEDLINE]
Related citations


Use of the lactulose to mannitol ratio to evaluate childhood environmental enteric dysfunction: a systematic review.
Denno DM, VanBuskirk K, Nelson ZC, Musser CA, Hay Burgess DC, Tarr PI
Clin Infect Dis. 2014 Nov 1; 59 Suppl 4S213-9. doi: 10.1093/cid/ciu541.

PMID:
    25305289
    [PubMed - indexed for MEDLINE]
Related citations


Environmental enteric dysfunction: pathogenesis, diagnosis, and clinical consequences.
Keusch GT, Denno DM, Black RE, Duggan C, Guerrant RL, Lavery JV, Nataro JP, Rosenberg IH, Ryan ET, Tarr PI, Ward H, Bhutta ZA, Coovadia H, Lima A, Ramakrishna B, Zaidi AK, Hay Burgess DC, Brewer T
Clin Infect Dis. 2014 Nov 1; 59 Suppl 4S207-12. doi: 10.1093/cid/ciu485.

PMID:
    25305288
    [PubMed - indexed for MEDLINE]
Related citations


Phenotypic and genotypic analysis of Clostridium difficile isolates: a single-center study.
Zhou Y, Burnham CA, Hink T, Chen L, Shaikh N, Wollam A, Sodergren E, Weinstock GM, Tarr PI, Dubberke ER
J Clin Microbiol. 2014 Dec; 52(12)4260-6. doi: 10.1128/JCM.02115-14.

PMID:
    25275005
    [PubMed - indexed for MEDLINE]
Related citations


Small bowel resection induces long-term changes in the enteric microbiota of mice.
Sommovilla J, Zhou Y, Sun RC, Choi PM, Diaz-Miron J, Shaikh N, Sodergren E, Warner BB, Weinstock GM, Tarr PI, Warner BW
J Gastrointest Surg. 2015 Jan; 19(1)56-64; discussion 64. doi: 10.1007/s11605-014-2631-0.

PMID:
    25183407
    [PubMed - in process]
Related citations


Patterned progression of bacterial populations in the premature infant gut.
La Rosa PS, Warner BB, Zhou Y, Weinstock GM, Sodergren E, Hall-Moore CM, Stevens HJ, Bennett WE Jr, Shaikh N, Linneman LA, Hoffmann JA, Hamvas A, Deych E, Shands BA, Shannon WD, Tarr PI
Proc Natl Acad Sci U S A. 2014 Aug 26; 111(34)12522-7. doi: 10.1073/pnas.1409497111.

PMID:
    25114261
    [PubMed - indexed for MEDLINE]
Related citations


Shiga toxin-producing Escherichia coli: a single-center, 11-year pediatric experience.
Schindler EI, Sellenriek P, Storch GA, Tarr PI, Burnham CA
J Clin Microbiol. 2014 Oct; 52(10)3647-53. doi: 10.1128/JCM.01231-14.

PMID:
    25078916
    [PubMed - indexed for MEDLINE]
Related citations


Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays.
VanDussen KL, Marinshaw JM, Shaikh N, Miyoshi H, Moon C, Tarr PI, Ciorba MA, Stappenbeck TS
Gut. 2015 Jun; 64(6)911-20. doi: 10.1136/gutjnl-2013-306651.

PMID:
    25007816
    [PubMed - indexed for MEDLINE]
Related citations