Patient Portal

Phillip I. Tarr, MD

Melvin E. Carnahan Professor of Pediatrics
Director, Pediatric Division of Gastroenterolgy and Nutrition

Specialty Areas

Pediatric Gastroenterology

Board Certifications

Pediatrics
Pediatric Gastroenterology

Hospital Affiliations

St. Louis Children's Hospital

Areas of Clinical Interest

Gastrointestinal diseases, e coli, infectious diseases, nutrition, food safety

  • Location(s)
  • Education
  • Publication & Research
  • In the News
  • Financial Disclosures

Location(s)

Location(s)

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Office Phone: 314-454-6173
Fax: 314-454-2412

Education

Education

Fellowship: Pediatric Gastroenterology, University of Washington School of Medicine and Children's Hosptial and Medical Center, Seattle, Washington 1989
Research Associate: Seattle Biomedical Intitute, Seattle, Washington 1987
Senior Fellow: Infectious Diseases, Department of Medicine, University of Washington School of Medicine, Seattle, Washington 1986
Residency: Pediatrics, University of Washington School of Medicine/Children's Orthopedic Hospital and Medical Center, Seattle, Washington 1983
Medical Degree: Yale University School of Medicine, New Haven, Connecticut 1980
A.B.: Biology, Brown University, Providence, Rhode Island 1975

Publication & Research

Publication & Research

A novel histological index for evaluation of environmental enteric dysfunction identifies geographic-specific features of enteropathy among children with suboptimal growth.
Liu TC, VanBuskirk K, Ali SA, Kelly MP, Holtz LR, Yilmaz OH, Sadiq K, Iqbal N, Amadi B, Syed S, Ahmed T, Moore S, Ndao IM, Isaacs MH, Pfeifer JD, Atlas H, Tarr PI, Denno DM, Moskaluk CA
PLoS Negl Trop Dis. 2020 Jan 13; 14(1)e0007975. doi: 10.1371/journal.pntd.0007975.

PMID:
    31929525
    [PubMed - as supplied by publisher]
Related citations


Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice.
Zhang Y, Shaikh N, Ferey JL, Wankhade UD, Chintapalli SV, Higgins CB, Crowley JR, Heitmeier MR, Stothard AI, Mihi B, Good MR, Higashiyama T, Swarts BM, Hruz PW, Shankar K, Tarr PI, DeBosch BJ
Gastroenterology. 2019 Dec 12; pii: S0016-5085(19)41894-5. doi: 10.1053/j.gastro.2019.11.295.

PMID:
    31838076
    [PubMed - as supplied by publisher]
Related citations


Discordant transmission of bacteria and viruses from mothers to babies at birth.
Maqsood R, Rodgers R, Rodriguez C, Handley SA, Ndao IM, Tarr PI, Warner BB, Lim ES, Holtz LR
Microbiome. 2019 Dec 10; 7(1)156. doi: 10.1186/s40168-019-0766-7.

PMID:
    31823811
    [PubMed - in process]
Related citations


Transdermal fluorescence detection of a dual fluorophore system for noninvasive point-of-care gastrointestinal permeability measurement.
Dorshow RB, Johnson JR, Debreczeny MP, Riley IR, Shieh JJ, Rogers TE, Hall-Moore C, Shaikh N, Rouggly-Nickless LC, Tarr PI
Biomed Opt Express. 2019 Oct 1; 10(10)5103-5116. doi: 10.1364/BOE.10.005103.

PMID:
    31646033
    [PubMed]
Related citations


Contribution and Interaction of Shiga Toxin Genes to <i>Escherichia coli</i> O157:H7 Virulence.
Tarr GAM, Stokowski T, Shringi S, Tarr PI, Freedman SB, Oltean HN, Rabinowitz PM, Chui L
Toxins (Basel). 2019 Oct 18; 11(10)pii: E607. doi: 10.3390/toxins11100607.

PMID:
    31635282
    [PubMed - in process]
Related citations


Persistent metagenomic signatures of early-life hospitalization and antibiotic treatment in the infant gut microbiota and resistome.
Gasparrini AJ, Wang B, Sun X, Kennedy EA, Hernandez-Leyva A, Ndao IM, Tarr PI, Warner BB, Dantas G
Nat Microbiol. 2019 Dec; 4(12)2285-2297. doi: 10.1038/s41564-019-0550-2.

PMID:
    31501537
    [PubMed - in process]
Related citations


Clinical interpretation of enteric molecular diagnostic tests.
Tarr GAM, Tarr PI, Freedman SB
Clin Microbiol Infect. 2019 Dec; 25(12)1454-1456. doi: 10.1016/j.cmi.2019.08.018.

PMID:
    31491461
    [PubMed - indexed for MEDLINE]
Related citations


Letter: Lactobacillus rhamnosus GG offers no benefit over placebo in children with acute gastroenteritis.
Schnadower D, Tarr PI, Freedman SB
Aliment Pharmacol Ther. 2019 Sep; 50(5)620-622. doi: 10.1111/apt.15418.

PMID:
    31414542
    [PubMed - in process]
Related citations


Undifferentiated Abdominal Pain in Children Presenting to the Pediatric Emergency Department.
Harris BR, Chinta SS, Colvin R, Schnadower D, Tarr PI, Sayuk GS
Clin Pediatr (Phila). 2019 Oct; 58(11-12)1212-1223. doi: 10.1177/0009922819867459.

PMID:
    31387380
    [PubMed - in process]
Related citations


Epithelial Indoleamine 2,3-Dioxygenase 1 Modulates Aryl Hydrocarbon Receptor and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota.
Alvarado DM, Chen B, Iticovici M, Thaker AI, Dai N, VanDussen KL, Shaikh N, Lim CK, Guillemin GJ, Tarr PI, Ciorba MA
Gastroenterology. 2019 Oct; 157(4)1093-1108.e11. doi: 10.1053/j.gastro.2019.07.013.

PMID:
    31325428
    [PubMed - indexed for MEDLINE]
Related citations


Transcriptomic analysis of enteropathy in Zambian children with severe acute malnutrition.
Chama M, Amadi BC, Chandwe K, Zyambo K, Besa E, Shaikh N, Ndao IM, Tarr PI, Storer C, Head R, Kelly P
EBioMedicine. 2019 Jul; 45456-463. doi: 10.1016/j.ebiom.2019.06.015.

PMID:
    31229436
    [PubMed - indexed for MEDLINE]
Related citations


Predicting Hemolytic Uremic Syndrome and Renal Failure in Shiga Toxin-Producing Escherichia coli Infected Children.
McKee RS, Schnadower D, Tarr PI, Xie J, Finkelstein Y, Desai N, Lane RD, Bergmann KR, Kaplan RL, Hariharan S, Cruz AT, Cohen DM, Dixon A, Ramgopal S, Rominger A, Powell EC, Kilgar J, Michelson KA, Beer D, Bitzan M, Pruitt CM, Yen K, Meckler GD, Plint AC, Bradin S, Abramo TJ, Gouin S, Kam AJ, Schuh A, Balamuth F, Hunley TE, Kanegaye JT, Jones NE, Avva U, Porter R, Fein DM, Louie JP, Freedman SB, Pediatric Emergency Medicine Collaborative Research Committee (PEMCRC)., Pediatric Emergency Research Canada (PERC).
Clin Infect Dis. 2019 May 24; pii: ciz432. doi: 10.1093/cid/ciz432.

PMID:
    31125419
    [PubMed - as supplied by publisher]
Related citations


Lactobacillus for Gastroenteritis in Children. Reply.
Schnadower D, Tarr PI, Freedman SB
N Engl J Med. 2019 May 9; 380(19)e36. doi: 10.1056/NEJMc1900909.

PMID:
    31067399
    [PubMed - indexed for MEDLINE]
Related citations


Impaired Chylomicron Assembly Modifies Hepatic Metabolism Through Bile Acid-Dependent and Transmissible Microbial Adaptations.
Xie Y, Matsumoto H, Kennedy S, Newberry EP, Moritz W, DeBosch BJ, Moley KH, Rubin DC, Warner BW, Kau AL, Tarr PI, Wylie TN, Wylie KM, Davidson NO
Hepatology. 2019 Oct; 70(4)1168-1184. doi: 10.1002/hep.30669.

PMID:
    31004524
    [PubMed - in process]
Related citations


Comparative Evaluation of Enteric Bacterial Culture and a Molecular Multiplex Syndromic Panel in Children with Acute Gastroenteritis.
Kellner T, Parsons B, Chui L, Berenger BM, Xie J, Burnham CA, Tarr PI, Lee BE, Nettel-Aguirre A, Szelewicki J, Vanderkooi OG, Pang XL, Zelyas N, Freedman SB
J Clin Microbiol. 2019 Jun; 57(6)pii: e00205-19. doi: 10.1128/JCM.00205-19.

PMID:
    30971465
    [PubMed - in process]
Related citations


Pigment Visibility on Rectal Swabs Used To Detect Enteropathogens: a Prospective Cohort Study.
Xie J, Tarr GAM, Ali S, Chui L, Pang XL, Lee BE, Vanderkooi OG, Tarr PI, Zhuo R, Parsons B, Berenger BM, Kim K, Freedman SB
J Clin Microbiol. 2019 Jun; 57(6)pii: e00213-19. doi: 10.1128/JCM.00213-19.

PMID:
    30944189
    [PubMed - in process]
Related citations


Performance of commercial tests for molecular detection of Shiga toxin-producing <i>Escherichia coli</i> (STEC): a systematic review and meta-analysis protocol.
Tarr GAM, Lin CY, Lorenzetti D, Chui L, Tarr PI, Hartling L, Vandermeer B, Freedman SB
BMJ Open. 2019 Mar 7; 9(3)e025950. doi: 10.1136/bmjopen-2018-025950.

PMID:
    30850413
    [PubMed - in process]
Related citations


Performance of Stool-testing Recommendations for Acute Gastroenteritis When Used to Identify Children With 9 Potential Bacterial Enteropathogens.
Tarr GAM, Chui L, Lee BE, Pang XL, Ali S, Nettel-Aguirre A, Vanderkooi OG, Berenger BM, Dickinson J, Tarr PI, Drews S, MacDonald J, Kim K, Freedman SB
Clin Infect Dis. 2019 Sep 13; 69(7)1173-1182. doi: 10.1093/cid/ciy1021.

PMID:
    30517612
    [PubMed - in process]
Related citations


Case definitions of hemolytic uremic syndrome following Escherichia coli O157:H7 infection vary in validity.
Tarr GAM, Oltean HN, Phipps AI, Rabinowitz P, Tarr PI
Int J Med Microbiol. 2018 Dec; 308(8)1121-1127. doi: 10.1016/j.ijmm.2018.10.002.

PMID:
    30466555
    [PubMed - indexed for MEDLINE]
Related citations


Lactobacillus rhamnosus GG versus Placebo for Acute Gastroenteritis in Children.
Schnadower D, Tarr PI, Casper TC, Gorelick MH, Dean JM, O'Connell KJ, Mahajan P, Levine AC, Bhatt SR, Roskind CG, Powell EC, Rogers AJ, Vance C, Sapien RE, Olsen CS, Metheney M, Dickey VP, Hall-Moore C, Freedman SB
N Engl J Med. 2018 Nov 22; 379(21)2002-2014. doi: 10.1056/NEJMoa1802598.

PMID:
    30462938
    [PubMed - indexed for MEDLINE]
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In the News

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians and health professionals are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians and health professionals work collaboratively with pharmaceutical, medical device or other medical care related companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our physicians and health professionals have an ownership or potential ownership interest in a commercial company; and/or are paid by a commercial company to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians or health professionals must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this website, physicians and health professionals earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following financial interests during calendar year 2018:

Company Name: Medibeacon

Royalties:

Equity: Yes

Consulting/Advisory Board: $20,000 - $39,999

Speaker Fees:

Reporting Date: May 01, 2019