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Peter Allen Humphrey, MD, PhD

Ladenson Professor, Pathology &Immunology
Professor, Urologic Surgery
Chief, Anatomic and Molecular Pathology

Specialty Areas

Urologic Pathology
Pathology

Board Certifications

Anatomic Pathology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Urologic (genitourinary) pathology, prostate cancer, bladder cancer, kidney cancer, testis cancer

  • Education
  • Publication & Research

Education

Education

Fellowship, Immunology: Duke University Medical School, Durham, NC 1987
BA, Chemistry and Biochemistry: University of Kansas, Kansas City, KS 1978
Medical Degree: University of Kansas, Kansas City, KS 1984
Residency, Anatomic Pathology: Duke University Medical Center Durham, NC 1988

Publication & Research

Publication & Research

Prostate Cancer Genomic Classifier Relates More Strongly to Gleason Grade Group than PI-RADS Score in Multi-Parametric Prostate MRI-Ultrasound Fusion Targeted Biopsies.
Martin DT, Ghabili K, Levi A, Humphrey PA, Sprenkle PC
Urology. 2018 Dec 12; pii: S0090-4295(18)31306-2. doi: 10.1016/j.urology.2018.12.001.

PMID:
    30552940
    [PubMed - as supplied by publisher]
Related citations


Dataset for the reporting of prostate carcinoma in core needle biopsy and transurethral resection and enucleation specimens: recommendations from the International Collaboration on Cancer Reporting (ICCR).
Egevad L, Judge M, Delahunt B, Humphrey PA, Kristiansen G, Oxley J, Rasiah K, Takahashi H, Trpkov K, Varma M, Wheeler TM, Zhou M, Srigley JR, Kench JG
Pathology. 2018 Nov 23; pii: S0031-3025(18)30481-1. doi: 10.1016/j.pathol.2018.10.003.

PMID:
    30477882
    [PubMed - as supplied by publisher]
Related citations


Intraoperative Consultation and Macroscopic Handling: The International Society of Urological Pathology (ISUP) Testicular Cancer Consultation Conference Recommendations.
Verrill C, Perry-Keene J, Srigley JR, Zhou M, Humphrey PA, Lopez-Beltran A, Egevad L, Ulbright TM, Tickoo SK, Epstein JI, Compérat E, Berney DM, Members of the ISUP Testicular Tumor Panel.
Am J Surg Pathol. 2018 Jun; 42(6)e33-e43. doi: 10.1097/PAS.0000000000001049.

PMID:
    29579010
    [PubMed - in process]
Related citations


Utility of Pathology Imagebase for standardisation of prostate cancer grading.
Egevad L, Delahunt B, Berney DM, Bostwick DG, Cheville J, Comperat E, Evans AJ, Fine SW, Grignon DJ, Humphrey PA, Hörnblad J, Iczkowski KA, Kench JG, Kristiansen G, Leite KRM, Magi-Galluzzi C, McKenney JK, Oxley J, Pan CC, Samaratunga H, Srigley JR, Takahashi H, True LD, Tsuzuki T, van der Kwast T, Varma M, Zhou M, Clements M
Histopathology. 2018 Jul; 73(1)8-18. doi: 10.1111/his.13471.

PMID:
    29359484
    [PubMed - indexed for MEDLINE]
Related citations


Variants of acinar adenocarcinoma of the prostate mimicking benign conditions.
Humphrey PA
Mod Pathol. 2018 Jan; 31(S1)S64-70. doi: 10.1038/modpathol.2017.137.

PMID:
    29297496
    [PubMed - in process]
Related citations


Proliferation index of different Gleason pattern 4 histomorphologies and associated pattern 3 adenocarcinoma of the prostate.
Fu L, Hwang M, Adeniran AJ, Humphrey PA
Hum Pathol. 2017 Dec; 701-5. doi: 10.1016/j.humpath.2017.06.007.

PMID:
    28666926
    [PubMed - indexed for MEDLINE]
Related citations


Histopathology of Prostate Cancer.
Humphrey PA
Cold Spring Harb Perspect Med. 2017 Oct 3; 7(10)pii: a030411. doi: 10.1101/cshperspect.a030411.

PMID:
    28389514
    [PubMed - indexed for MEDLINE]
Related citations


Negative Multiparametric Magnetic Resonance Imaging of the Prostate Predicts Absence of Clinically Significant Prostate Cancer on 12-Core Template Prostate Biopsy.
Lu AJ, Syed JS, Nguyen KA, Nawaf CB, Rosoff J, Spektor M, Levi A, Humphrey PA, Weinreb JC, Schulam PG, Sprenkle PC
Urology. 2017 Jul; 105118-122. doi: 10.1016/j.urology.2017.01.048.

PMID:
    28322902
    [PubMed - indexed for MEDLINE]
Related citations


Immunohistochemical and molecular characterizations in urothelial carcinoma of bladder in patients less than 45 years.
Weyerer V, Schneckenpointner R, Filbeck T, Burger M, Hofstaedter F, Wild PJ, Fine SW, Humphrey PA, Dehner LP, Amin MB, Rüschoff J, Boltze C, Tannapfel A, Zwarthoff E, Lopez-Beltran A, Montironi R, Langner C, Stoehr R, Hartmann A, Giedl J
J Cancer. 2017; 8(3)323-331. doi: 10.7150/jca.17482.

PMID:
    28261332
    [PubMed]
Related citations


Contemporary Gleason Grading of Prostatic Carcinoma: An Update With Discussion on Practical Issues to Implement the 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma.
Epstein JI, Amin MB, Reuter VE, Humphrey PA
Am J Surg Pathol. 2017 Apr; 41(4)e1-e7. doi: 10.1097/PAS.0000000000000820.

PMID:
    28177964
    [PubMed - indexed for MEDLINE]
Related citations


The World Health Organization 2016 classification of testicular non-germ cell tumours: a review and update from the International Society of Urological Pathology Testis Consultation Panel.
Idrees MT, Ulbright TM, Oliva E, Young RH, Montironi R, Egevad L, Berney D, Srigley JR, Epstein JI, Tickoo SK, Members of the International Society of Urological Pathology Testicular Tumour Panel.
Histopathology. 2017 Mar; 70(4)513-521. doi: 10.1111/his.13115.

PMID:
    27801954
    [PubMed - indexed for MEDLINE]
Related citations


The World Health Organization 2016 classification of testicular germ cell tumours: a review and update from the International Society of Urological Pathology Testis Consultation Panel.
Williamson SR, Delahunt B, Magi-Galluzzi C, Algaba F, Egevad L, Ulbright TM, Tickoo SK, Srigley JR, Epstein JI, Berney DM, Members of the ISUP Testicular Tumour Panel.
Histopathology. 2017 Feb; 70(3)335-346. doi: 10.1111/his.13102.

PMID:
    27747907
    [PubMed - indexed for MEDLINE]
Related citations


Gleason grade 4 prostate adenocarcinoma patterns: an interobserver agreement study among genitourinary pathologists.
Kweldam CF, Nieboer D, Algaba F, Amin MB, Berney DM, Billis A, Bostwick DG, Bubendorf L, Cheng L, Compérat E, Delahunt B, Egevad L, Evans AJ, Hansel DE, Humphrey PA, Kristiansen G, van der Kwast TH, Magi-Galluzzi C, Montironi R, Netto GJ, Samaratunga H, Srigley JR, Tan PH, Varma M, Zhou M, van Leenders GJ
Histopathology. 2016 Sep; 69(3)441-9. doi: 10.1111/his.12976.

PMID:
    27028587
    [PubMed - indexed for MEDLINE]
Related citations


The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part B: Prostate and Bladder Tumours.
Humphrey PA, Moch H, Cubilla AL, Ulbright TM, Reuter VE
Eur Urol. 2016 Jul; 70(1)106-119. doi: 10.1016/j.eururo.2016.02.028.

PMID:
    26996659
    [PubMed - indexed for MEDLINE]
Related citations


The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours.
Moch H, Cubilla AL, Humphrey PA, Reuter VE, Ulbright TM
Eur Urol. 2016 Jul; 70(1)93-105. doi: 10.1016/j.eururo.2016.02.029.

PMID:
    26935559
    [PubMed - indexed for MEDLINE]
Related citations


[The 2014 consensus conference of the ISUP on Gleason grading of prostatic carcinoma].
Kristiansen G, Egevad L, Amin M, Delahunt B, Srigley JR, Humphrey PA, Epstein JI, Graduierungskommittee.
Pathologe. 2016 Feb; 37(1)17-26. doi: 10.1007/s00292-015-0136-6.

PMID:
    26809207
    [PubMed - indexed for MEDLINE]
Related citations


Morphologic Updates in Prostate Pathology.
Adeniran AJ, Humphrey PA
Surg Pathol Clin. 2015 Dec; 8(4)539-60. doi: 10.1016/j.path.2015.08.002.

PMID:
    26612214
    [PubMed - indexed for MEDLINE]
Related citations


Hereditary Renal Cell Carcinoma Syndromes: Clinical, Pathologic, and Genetic Features.
Adeniran AJ, Shuch B, Humphrey PA
Am J Surg Pathol. 2015 Dec; 39(12)e1-e18. doi: 10.1097/PAS.0000000000000562.

PMID:
    26559379
    [PubMed - indexed for MEDLINE]
Related citations


The 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma: Definition of Grading Patterns and Proposal for a New Grading System.
Epstein JI, Egevad L, Amin MB, Delahunt B, Srigley JR, Humphrey PA, Grading Committee.
Am J Surg Pathol. 2016 Feb; 40(2)244-52. doi: 10.1097/PAS.0000000000000530.

PMID:
    26492179
    [PubMed - indexed for MEDLINE]
Related citations


NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence.
Manda KR, Tripathi P, Hsi AC, Ning J, Ruzinova MB, Liapis H, Bailey M, Zhang H, Maher CA, Humphrey PA, Andriole GL, Ding L, You Z, Chen F
Oncogene. 2016 Jun 23; 35(25)3282-92. doi: 10.1038/onc.2015.389.

PMID:
    26477312
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Research interests focus on diagnosis, particularly tissue diagnosis, of urologic malignancies, including prostate cancer, kidney cancer, testis cancer, and bladder cancer. Investigations are also directed toward discovery and development of immunophenotypic and molecular genetic markers of these malignancies.