FollowMyHealth Patient Portal

Faculty Physicians

Paul Santiago, MD

Associate Professor, Neurological Surgery and Orthopedic Surgery

Specialty Areas

Spine Surgery - Neurosurgery
Neurological Surgery
Spinal Cord Tumors
Cervical Spine Surgery

Board Certifications

Neurological Surgery

Areas of Clinical Interest

General neurosurgery, spinal disorders resulting from degenerative disease, spondylosis, spondylolithesis, tumors, cancer, inflammatory disease, ankylosing spondylitis, rheumatoid arthritis, infections, congenital disorders, cervical spine surgery, spinal instrumentation, minimally invasive surgery, thoracoscopic surgery; disorders of cervical, thoracic and lumbar spine; disorders of craniocervical junction, head injury, spinal cord injury

  • Maps & Directions
  • Education
  • Publication & Research
  • In the News
  • Financial Disclosures

Maps & Directions

Maps & Directions

West County ENT

605 Old Ballas Road
Suite 124
Creve Coeur, MO 63141

Suite: Suite 211
Office Phone: (314) 362-3577
Fax: (314) 362-2107

Center for Advanced Medicine
Neurosurgical Cervical Spine Institute and Spine Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 6
Office Phone: (314) 362-3577
Fax: (314) 362-2107

Education

Education

Fellowship: Spine in Neurological Surgery, University of Chicago, Chicago, Illinois 2003
Chief Residency: Neurological Surgery, University of Washington, Seattle, Washington 2002
Residency: Neurological Surgery, University of Washington, Seattle, Washington 2000
Medical Degree: Yale School of Medicine, New Haven, Connecticutt 1995
BSc with Honors: Biology, Stanford University, 1990

Publication & Research

Publication & Research

Risk factors for accident death in the U.S. Army, 2004-2009.
Lewandowski-Romps L, Peterson C, Berglund PA, Collins S, Cox K, Hauret K, Jones B, Kessler RC, Mitchell C, Park N, Schoenbaum M, Stein MB, Ursano RJ, Heeringa SG, Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) Collaborators
Am J Prev Med. 2014 Dec; 47(6)745-53. doi: 10.1016/j.amepre.2014.07.052.

PMID:
    25441238
    [PubMed - indexed for MEDLINE]
Related citations


The Army study to assess risk and resilience in servicemembers (Army STARRS).
Ursano RJ, Colpe LJ, Heeringa SG, Kessler RC, Schoenbaum M, Stein MB, Army STARRS collaborators
Psychiatry. 2014 Summer; 77(2)107-19. doi: 10.1521/psyc.2014.77.2.107.

PMID:
    24865195
    [PubMed - indexed for MEDLINE]
Related citations


p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer.
McFadden DG, Vernon A, Santiago PM, Martinez-McFaline R, Bhutkar A, Crowley DM, McMahon M, Sadow PM, Jacks T
Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16)E1600-9. doi: 10.1073/pnas.1404357111.

PMID:
    24711431
    [PubMed - indexed for MEDLINE]
Related citations


Screening for decreased glomerular filtration rate and associated risk factors in a cohort of HIV-infected patients in a middle-income country.
Santiago P, Grinsztejn B, Friedman RK, Cunha CB, Coelho LE, Luz PM, de Oliveira AV, Moreira RI, Cardoso SW, Veloso VG, Suassuna JH
PLoS One. 2014; 9(4)e93748. doi: 10.1371/journal.pone.0093748.

PMID:
    24699873
    [PubMed - indexed for MEDLINE]
Related citations


Management of the alveolar cleft.
Santiago PE, Schuster LA, Levy-Bercowski D
Clin Plast Surg. 2014 Apr; 41(2)219-32. doi: 10.1016/j.cps.2014.01.001.

PMID:
    24607190
    [PubMed - indexed for MEDLINE]
Related citations


Prevalence and correlates of suicidal behavior among soldiers: results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS).
Nock MK, Stein MB, Heeringa SG, Ursano RJ, Colpe LJ, Fullerton CS, Hwang I, Naifeh JA, Sampson NA, Schoenbaum M, Zaslavsky AM, Kessler RC, Army STARRS Collaborators
JAMA Psychiatry. 2014 May; 71(5)514-22.

PMID:
    24590178
    [PubMed - indexed for MEDLINE]
Related citations


Thirty-day prevalence of DSM-IV mental disorders among nondeployed soldiers in the US Army: results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS).
Kessler RC, Heeringa SG, Stein MB, Colpe LJ, Fullerton CS, Hwang I, Naifeh JA, Nock MK, Petukhova M, Sampson NA, Schoenbaum M, Zaslavsky AM, Ursano RJ, Army STARRS Collaborators
JAMA Psychiatry. 2014 May; 71(5)504-13.

PMID:
    24590120
    [PubMed - indexed for MEDLINE]
Related citations


Predictors of suicide and accident death in the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS): results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS).
Schoenbaum M, Kessler RC, Gilman SE, Colpe LJ, Heeringa SG, Stein MB, Ursano RJ, Cox KL, Army STARRS Collaborators
JAMA Psychiatry. 2014 May; 71(5)493-503.

PMID:
    24590048
    [PubMed - indexed for MEDLINE]
Related citations


Clinical reappraisal of the Composite International Diagnostic Interview Screening Scales (CIDI-SC) in the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS).
Kessler RC, Santiago PN, Colpe LJ, Dempsey CL, First MB, Heeringa SG, Stein MB, Fullerton CS, Gruber MJ, Naifeh JA, Nock MK, Sampson NA, Schoenbaum M, Zaslavsky AM, Ursano RJ
Int J Methods Psychiatr Res. 2013 Dec; 22(4)303-21. doi: 10.1002/mpr.1398.

PMID:
    24318219
    [PubMed - indexed for MEDLINE]
Related citations


A comparison between flexible electrogoniometers, inclinometers and three-dimensional video analysis system for recording neck movement.
Carnaz L, Moriguchi CS, de Oliveira AB, Santiago PR, Caurin GA, Hansson GÅ, Coury HJ
Med Eng Phys. 2013 Nov; 35(11)1629-37. doi: 10.1016/j.medengphy.2013.05.014.

PMID:
    23806418
    [PubMed - indexed for MEDLINE]
Related citations


Maternal-fetal thyroid function at the time of birth and its relation with iodine intake.
Velasco I, Martín J, Gallego M, Gutiérrez-Repiso C, Santiago P, López-Siguero JP, Mesa EG, Peral JH, Pérez V, García-Fuentes E, Soriguer F
Thyroid. 2013 Dec; 23(12)1619-26. doi: 10.1089/thy.2013.0035.

PMID:
    23763592
    [PubMed - indexed for MEDLINE]
Related citations


Discovery of (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and (R)-4-cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline (ELND007): metabolically stable γ-secretase Inhibitors that selectively inhibit the production of amyloid-β over Notch.
Probst G, Aubele DL, Bowers S, Dressen D, Garofalo AW, Hom RK, Konradi AW, Marugg JL, Mattson MN, Neitzel ML, Semko CM, Sham HL, Smith J, Sun M, Truong AP, Ye XM, Xu YZ, Dappen MS, Jagodzinski JJ, Keim PS, Peterson B, Latimer LH, Quincy D, Wu J, Goldbach E, Ness DK, Quinn KP, Sauer JM, Wong K, Zhang H, Zmolek W, Brigham EF, Kholodenko D, Hu K, Kwong GT, Lee M, Liao A, Motter RN, Sacayon P, Santiago P, Willits C, Bard F, Bova MP, Hemphill SS, Nguyen L, Ruslim L, Tanaka K, Tanaka P, Wallace W, Yednock TA, Basi GS
J Med Chem. 2013 Jul 11; 56(13)5261-74. doi: 10.1021/jm301741t.

PMID:
    23713656
    [PubMed - indexed for MEDLINE]
Related citations


Biopsy of the superficial cortex: predictors of effectiveness and outcomes.
Hawasli AH, Buckley RT, Gao F, Limbrick DD, Smyth MD, Leonard JR, Santiago P, Stewart TJ, Park TS, Grubb RL, Dowling JL, Leuthardt EC, Rich KM, Zipfel GJ, Dacey RG, Chicoine MR
Neurosurgery. 2013 Aug; 73(2)224-31; discussion 231-2; quiz 232. doi: 10.1227/01.neu.0000430310.63702.3e.

PMID:
    23632761
    [PubMed - indexed for MEDLINE]
Related citations


Are readmission rates on a neurosurgical service indicators of quality of care?
Shah MN, Stoev IT, Sanford DE, Gao F, Santiago P, Jaques DP, Dacey RG Jr
J Neurosurg. 2013 Oct; 119(4)1043-9. doi: 10.3171/2013.3.JNS121769.

PMID:
    23621593
    [PubMed - indexed for MEDLINE]
Related citations


A systematic review of PTSD prevalence and trajectories in DSM-5 defined trauma exposed populations: intentional and non-intentional traumatic events.
Santiago PN, Ursano RJ, Gray CL, Pynoos RS, Spiegel D, Lewis-Fernandez R, Friedman MJ, Fullerton CS
PLoS One. 2013; 8(4)e59236. doi: 10.1371/journal.pone.0059236.

PMID:
    23593134
    [PubMed - indexed for MEDLINE]
Related citations


Sit-to-stand movement in children with hemiplegic cerebral palsy: relationship with knee extensor torque and social participation.
dos Santos AN, Pavão SL, Santiago PR, Salvini Tde F, Rocha NA
Res Dev Disabil. 2013 Jun; 34(6)2023-32. doi: 10.1016/j.ridd.2013.03.021.

PMID:
    23584182
    [PubMed - indexed for MEDLINE]
Related citations


Triazolopyridazine LRRK2 kinase inhibitors.
Franzini M, Ye XM, Adler M, Aubele DL, Garofalo AW, Gauby S, Goldbach E, Probst GD, Quinn KP, Santiago P, Sham HL, Tam D, Truong A, Ren Z
Bioorg Med Chem Lett. 2013 Apr 1; 23(7)1967-73. doi: 10.1016/j.bmcl.2013.02.043.

PMID:
    23454015
    [PubMed - indexed for MEDLINE]
Related citations


Infant neurocognitive development is independent of the use of iodised salt or iodine supplements given during pregnancy.
Santiago P, Velasco I, Muela JA, Sánchez B, Martínez J, Rodriguez A, Berrio M, Gutierrez-Repiso C, Carreira M, Moreno A, García-Fuentes E, Soriguer F
Br J Nutr. 2013 Sep 14; 110(5)831-9. doi: 10.1017/S0007114512005880.

PMID:
    23375074
    [PubMed - indexed for MEDLINE]
Related citations


Novel cinnoline-based inhibitors of LRRK2 kinase activity.
Garofalo AW, Adler M, Aubele DL, Bowers S, Franzini M, Goldbach E, Lorentzen C, Neitz RJ, Probst GD, Quinn KP, Santiago P, Sham HL, Tam D, Truong AP, Ye XM, Ren Z
Bioorg Med Chem Lett. 2013 Jan 1; 23(1)71-4. doi: 10.1016/j.bmcl.2012.11.021.

PMID:
    23219325
    [PubMed - indexed for MEDLINE]
Related citations


Description of combat and operational stress control in Regional Command East, Afghanistan.
Ogle AD, Bradley D, Santiago P, Reynolds D
Mil Med. 2012 Nov; 177(11)1279-86.

PMID:
    23198502
    [PubMed - indexed for MEDLINE]
Related citations

In the News

In the News

Paul Santiago, MD

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2014.

Company Name: Corelink

Royalties:

Equity: No

Consulting/Advisory Board: $1,000 - $10,000

Speaker Fees:

Reporting Date: May 01, 2015


Company Name: Zimmer

Royalties: $25,001 - $50,000

Equity: No

Consulting/Advisory Board:

Speaker Fees: $25,001 - $50,000

Reporting Date: May 01, 2015


Company Name: Aesculap

Royalties:

Equity: No

Consulting/Advisory Board: $25,001 - $50,000

Speaker Fees:

Reporting Date: May 01, 2015

Areas of Research Interest

Patient safety and quality improvement in patient care.