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Nicholas O. Davidson, MD, DSc

John E. and Adaline Simon Professor of Medicine and Developmental Biology
Chief, Division of Gastroenterology
Director, Digestive Disease Research Core Center

Specialty Areas

Gastroenterology
Gastrointestinal Oncology
Gastrointestinal Disease

Board Certifications

Gastroenterology
Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Familial gastrointestinal cancer syndromes, hereditary polyposis syndromes, colorectal cancer genetics

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Gastrointestinal Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 8
Office Phone: 314-747-2066
Fax: 314-362-2033

Education

Education

DSc Degree: University of London, London, England 2002
Fellowship: Gastrointestinal, Columbia-Presbyterian Medical Center, College of Physicians and Surgeons, New York 1982
Residency: Queen Elizabeth Hospital, Birmingham, England 1977
Medical Degree: Kings College Hospital Medical School, London, England 1974
B.S.: Kings College, London, England 1974

Publication & Research

Publication & Research

Cd36 knockout mice are protected against lithogenic diet induced gallstones.
Xie Y, Cifarelli V, Pietka T, Newberry EP, Kennedy SM, Khalifeh-Soltani A, Clugston R, Atabai K, Abumrad NA, Davidson NO
J Lipid Res. 2017 Jun 20; pii: jlr.M077479. doi: 10.1194/jlr.M077479.

PMID:
    28634191
    [PubMed - as supplied by publisher]
Related citations


Differences in Effectiveness and Use of Robotic Surgery in Patients Undergoing Minimally Invasive Colectomy.
Schootman M, Hendren S, Loux T, Ratnapradipa K, Eberth JM, Davidson NO
J Gastrointest Surg. 2017 May 31; doi: 10.1007/s11605-017-3460-8.

PMID:
    28567574
    [PubMed - as supplied by publisher]
Related citations


A stable but reversible integrated surrogate reporter for assaying CRISPR/Cas9-stimulated homology-directed repair.
Wen Y, Liao G, Pritchard T, Zhao TT, Connelly JP, Pruett-Miller SM, Blanc V, Davidson NO, Madison BB
J Biol Chem. 2017 Apr 14; 292(15)6148-6162. doi: 10.1074/jbc.M117.777722.

PMID:
    28228480
    [PubMed - indexed for MEDLINE]
Related citations


A single transcription factor is sufficient to induce and maintain secretory cell architecture.
Lo HG, Jin RU, Sibbel G, Liu D, Karki A, Joens MS, Madison BB, Zhang B, Blanc V, Fitzpatrick JA, Davidson NO, Konieczny SF, Mills JC
Genes Dev. 2017 Jan 15; 31(2)154-171. doi: 10.1101/gad.285684.116.

PMID:
    28174210
    [PubMed - in process]
Related citations


CD36 deficiency impairs the small intestinal barrier and induces subclinical inflammation in mice.
Cifarelli V, Ivanov S, Xie Y, Son NH, Saunders BT, Pietka TA, Shew TM, Yoshino J, Sundaresan S, Davidson NO, Goldberg IJ, Gelman AE, Zinselmeyer BH, Randolph GJ, Abumrad NA
Cell Mol Gastroenterol Hepatol. 2017 Jan; 3(1)82-98. doi: 10.1016/j.jcmgh.2016.09.001.

PMID:
    28066800
    [PubMed - in process]
Related citations


How to Prepare for and Write a Grant: Personal Perspectives.
Davidson NO, El-Serag HB
Gastroenterology. 2017 Jan; 152(1)7-11. doi: 10.1053/j.gastro.2016.11.025.

PMID:
    27889573
    [PubMed - in process]
Related citations


Prevention of hepatic fibrosis with liver microsomal triglyceride transfer protein deletion in liver fatty acid binding protein null mice.
Newberry EP, Xie Y, Kennedy SM, Graham MJ, Crooke RM, Jiang H, Chen A, Ory DS, Davidson NO
Hepatology. 2017 Mar; 65(3)836-852. doi: 10.1002/hep.28941.

PMID:
    27862118
    [PubMed - in process]
Related citations


Adoption of Robotic Technology for Treating Colorectal Cancer.
Schootman M, Hendren S, Ratnapradipa K, Stringer L, Davidson NO
Dis Colon Rectum. 2016 Nov; 59(11)1011-1018.

PMID:
    27749475
    [PubMed - indexed for MEDLINE]
Related citations


RNA Editing: Another Level of Somatic Mutagenic Activity in Gastric Cancer.
Blanc V, Davidson NO
Gastroenterology. 2016 Oct; 151(4)584-7. doi: 10.1053/j.gastro.2016.08.044.

PMID:
    27590792
    [PubMed - in process]
Related citations


Parent-of-origin effects of A1CF and AGO2 on testicular germ-cell tumors, testicular abnormalities, and fertilization bias.
Carouge D, Blanc V, Knoblaugh SE, Hunter RJ, Davidson NO, Nadeau JH
Proc Natl Acad Sci U S A. 2016 Sep 13; 113(37)E5425-33. doi: 10.1073/pnas.1604773113.

PMID:
    27582469
    [PubMed - in process]
Related citations


Characterization of Colorectal Cancer Development in Apc (min/+) Mice.
Nalbantoglu I, Blanc V, Davidson NO
Methods Mol Biol. 2016; 1422309-27. doi: 10.1007/978-1-4939-3603-8_27.

PMID:
    27246043
    [PubMed - in process]
Related citations


Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis.
DeBosch BJ, Heitmeier MR, Mayer AL, Higgins CB, Crowley JR, Kraft TE, Chi M, Newberry EP, Chen Z, Finck BN, Davidson NO, Yarasheski KE, Hruz PW, Moley KH
Sci Signal. 2016 Feb 23; 9(416)ra21. doi: 10.1126/scisignal.aac5472.

PMID:
    26905426
    [PubMed - indexed for MEDLINE]
Related citations


Microsomal Triglyceride Transfer Protein Transfers and Determines Plasma Concentrations of Ceramide and Sphingomyelin but Not Glycosylceramide.
Iqbal J, Walsh MT, Hammad SM, Cuchel M, Tarugi P, Hegele RA, Davidson NO, Rader DJ, Klein RL, Hussain MM
J Biol Chem. 2015 Oct 23; 290(43)25863-75. doi: 10.1074/jbc.M115.659110.

PMID:
    26350457
    [PubMed - indexed for MEDLINE]
Related citations


Identification of Medically Actionable Secondary Findings in the 1000 Genomes.
Olfson E, Cottrell CE, Davidson NO, Gurnett CA, Heusel JW, Stitziel NO, Chen LS, Hartz S, Nagarajan R, Saccone NL, Bierut LJ
PLoS One. 2015; 10(9)e0135193. doi: 10.1371/journal.pone.0135193.

PMID:
    26332594
    [PubMed - indexed for MEDLINE]
Related citations


Phenotypic divergence in two lines of L-Fabp-/- mice reflects substrain differences and environmental modifiers.
Newberry EP, Kennedy S, Xie Y, Luo J, Jiang H, Ory DS, Davidson NO
Am J Physiol Gastrointest Liver Physiol. 2015 Oct 15; 309(8)G648-61. doi: 10.1152/ajpgi.00170.2015.

PMID:
    26251469
    [PubMed - indexed for MEDLINE]
Related citations


The utility of Google Trends data to examine interest in cancer screening.
Schootman M, Toor A, Cavazos-Rehg P, Jeffe DB, McQueen A, Eberth J, Davidson NO
BMJ Open. 2015 Jun 8; 5(6)e006678. doi: 10.1136/bmjopen-2014-006678.

PMID:
    26056120
    [PubMed - indexed for MEDLINE]
Related citations


Novel APC promoter and exon 1B deletion and allelic silencing in three mutation-negative classic familial adenomatous polyposis families.
Lin Y, Lin S, Baxter MD, Lin L, Kennedy SM, Zhang Z, Goodfellow PJ, Chapman WC, Davidson NO
Genome Med. 2015; 7(1)42. doi: 10.1186/s13073-015-0148-0.

PMID:
    25941542
    [PubMed]
Related citations


miR-217 regulates ethanol-induced hepatic inflammation by disrupting sirtuin 1-lipin-1 signaling.
Yin H, Liang X, Jogasuria A, Davidson NO, You M
Am J Pathol. 2015 May; 185(5)1286-96. doi: 10.1016/j.ajpath.2015.01.030.

PMID:
    25797648
    [PubMed - indexed for MEDLINE]
Related citations


Overview and introduction: thematic review series on intestinal lipid metabolism.
Davidson NO
J Lipid Res. 2015 Mar; 56(3)487-8. doi: 10.1194/jlr.E058503.

PMID:
    25684761
    [PubMed - indexed for MEDLINE]
Related citations


A trimming-and-retrieving alignment scheme for reduced representation bisulfite sequencing.
Wang X, Yu X, Zhu W, McCombie WR, Antoniou E, Powers RS, Davidson NO, Li E, Williams J
Bioinformatics. 2015 Jun 15; 31(12)2040-2. doi: 10.1093/bioinformatics/btv089.

PMID:
    25681254
    [PubMed - indexed for MEDLINE]
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