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Murali Mohan Chakinala, MD

Professor, Medicine
Division of Pulmonary and Critical Care Medicine

Specialty Areas

Pulmonary Disease

Board Certifications

Internal Medicine
Pulmonary Disease
Critical Care

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Pulmonary hypertension,thromboembolic disease, hereditary hemorrhagic telangiectasias, pulmonary arteriovenous malformations

  • Maps & Directions
  • Education
  • Publication & Research
  • In the News
  • Financial Disclosures

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-454-8917
Fax: 314-454-5571

Education

Education

Fellowship: Pulmonary And Critical Care Medicine, Washington University School of Medicine, St. Louis, Missouri 2002
Residency: Internal Medicine, University of Texas, Southwestern Medical Center, Dallas, Texas 1997
Medical Degree: Vanderbilt University School of Medicine, Nashville, Tennesee 1994
B.A.: Economics, Duke University, Durham, North Carolina 1990

Publication & Research

Publication & Research

Recommendations for the use of oral treprostinil in clinical practice: a Delphi consensus project pulmonary circulation.
Rahaghi FF, Feldman JP, Allen RP, Tapson V, Safdar Z, Balasubramanian VP, Shapiro S, Mathier MA, Elwing JM, Chakinala MM, White RJ
Pulm Circ. 2017 Mar; 7(1)167-174. doi: 10.1086/690109.

PMID:
    28680576
    [PubMed]
Related citations


Recommendations for the clinical management of patients receiving macitentan for pulmonary arterial hypertension (PAH): A Delphi consensus document.
Rahaghi FF, Alnuaimat HM, Awdish RLA, Balasubramanian VP, Bourge RC, Burger CD, Butler J, Cauthen CG, Chakinala MM, deBoisblanc BP, Eggert MS, Engel P, Feldman J, McConnell JW, Park M, Sager JS, Sood N, Palevsky HI
Pulm Circ. 2017 Jul-Sep; 7(3)702-711. doi: 10.1177/2045893217721695.

PMID:
    28671484
    [PubMed]
Related citations


Totally Implantable IV Treprostinil Therapy in Pulmonary Hypertension Assessment of the Implantation Procedure.
Waxman AB, McElderry HT, Gomberg-Maitland M, Burke MC, Ross EL, Bersohn MM, Pangarkar SS, Tarver JH, Zwicke DL, Feldman JP, Chakinala MM, Frantz RP, Thompson GB, Torres F, Rauck RL, Clagg K, Durst L, Li P, Morris M, Southall KL, Peterson L, Bourge RC
Chest. 2017 Jun 3; pii: S0012-3692(17)31021-8. doi: 10.1016/j.chest.2017.04.188.

PMID:
    28583617
    [PubMed - as supplied by publisher]
Related citations


Effect of Topical Intranasal Therapy on Epistaxis Frequency in Patients With Hereditary Hemorrhagic Telangiectasia: A Randomized Clinical Trial.
Whitehead KJ, Sautter NB, McWilliams JP, Chakinala MM, Merlo CA, Johnson MH, James M, Everett EM, Clancy MS, Faughnan ME, Oh SP, Olitsky SE, Pyeritz RE, Gossage JR
JAMA. 2016 Sep 6; 316(9)943-51. doi: 10.1001/jama.2016.11724.

PMID:
    27599329
    [PubMed - indexed for MEDLINE]
Related citations


Transition from parenteral to oral treprostinil in pulmonary arterial hypertension.
Chakinala MM, Feldman JP, Rischard F, Mathier M, Broderick M, Leedom N, Laliberte K, White RJ
J Heart Lung Transplant. 2017 Feb; 36(2)193-201. doi: 10.1016/j.healun.2016.06.019.

PMID:
    27469018
    [PubMed - in process]
Related citations


Managing the Patient with Pulmonary Hypertension: Specialty Care Centers, Coordinated Care, and Patient Support.
Chakinala MM, Duncan M, Wirth J
Cardiol Clin. 2016 Aug; 34(3)489-500. doi: 10.1016/j.ccl.2016.04.008.

PMID:
    27443143
    [PubMed - indexed for MEDLINE]
Related citations


Treprostinil Administered to Treat Pulmonary Arterial Hypertension Using a Fully Implantable Programmable Intravascular Delivery System: Results of the DelIVery for PAH Trial.
Bourge RC, Waxman AB, Gomberg-Maitland M, Shapiro SM, Tarver JH 3rd, Zwicke DL, Feldman JP, Chakinala MM, Frantz RP, Torres F, Cerkvenik J, Morris M, Thalin M, Peterson L, Rubin LJ
Chest. 2016 Jul; 150(1)27-34. doi: 10.1016/j.chest.2015.11.005.

PMID:
    27396777
    [PubMed - indexed for MEDLINE]
Related citations


Initial Use of Ambrisentan plus Tadalafil in Pulmonary Arterial Hypertension.
Galiè N, Barberà JA, Frost AE, Ghofrani HA, Hoeper MM, McLaughlin VV, Peacock AJ, Simonneau G, Vachiery JL, Grünig E, Oudiz RJ, Vonk-Noordegraaf A, White RJ, Blair C, Gillies H, Miller KL, Harris JH, Langley J, Rubin LJ, AMBITION Investigators.
N Engl J Med. 2015 Aug 27; 373(9)834-44. doi: 10.1056/NEJMoa1413687.

PMID:
    26308684
    [PubMed - indexed for MEDLINE]
Related citations


Hospitalization and survival in patients using epoprostenol for injection in the PROSPECT observational study.
Frantz RP, Schilz RJ, Chakinala MM, Badesch DB, Frost AE, McLaughlin VV, Barst RJ, Rosenberg DM, Miller DP, Hartline BK, Benton WW, Farber HW
Chest. 2015 Feb; 147(2)484-494. doi: 10.1378/chest.14-1004.

PMID:
    25320967
    [PubMed - indexed for MEDLINE]
Related citations


From short-term benefits to long-term outcomes: the evolution of clinical trials in pulmonary arterial hypertension.
Chakinala MM, Barst R
Pulm Circ. 2013 Sep; 3(3)507-22. doi: 10.1086/674456.

PMID:
    24618537
    [PubMed]
Related citations


World Health Organization group 5 pulmonary hypertension.
Lahm T, Chakinala MM
Clin Chest Med. 2013 Dec; 34(4)753-78. doi: 10.1016/j.ccm.2013.08.005.

PMID:
    24267303
    [PubMed - indexed for MEDLINE]
Related citations


Effects of phosphodiesterase type 5 inhibition on systemic and pulmonary hemodynamics and ventricular function in patients with severe symptomatic aortic stenosis.
Lindman BR, Zajarias A, Madrazo JA, Shah J, Gage BF, Novak E, Johnson SN, Chakinala MM, Hohn TA, Saghir M, Mann DL
Circulation. 2012 May 15; 125(19)2353-62. doi: 10.1161/CIRCULATIONAHA.111.081125.

PMID:
    22447809
    [PubMed - indexed for MEDLINE]
Related citations


Modulating the nitric oxide - cyclic GMP pathway in the pressure-overloaded left ventricle and group II pulmonary hypertension.
Lindman BR, Chakinala MM
Int J Clin Pract Suppl. 2010 Nov; (168)15-22. doi: 10.1111/j.1742-1241.2010.02524.x.

PMID:
    20939842
    [PubMed - indexed for MEDLINE]
Related citations


Azithromycin is associated with increased survival in lung transplant recipients with bronchiolitis obliterans syndrome.
Jain R, Hachem RR, Morrell MR, Trulock EP, Chakinala MM, Yusen RD, Huang HJ, Mohanakumar T, Patterson GA, Walter MJ
J Heart Lung Transplant. 2010 May; 29(5)531-7. doi: 10.1016/j.healun.2009.12.003.

PMID:
    20133163
    [PubMed - indexed for MEDLINE]
Related citations


Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial.
Simonneau G, Rubin LJ, Galiè N, Barst RJ, Fleming TR, Frost AE, Engel PJ, Kramer MR, Burgess G, Collings L, Cossons N, Sitbon O, Badesch DB, PACES Study Group.
Ann Intern Med. 2008 Oct 21; 149(8)521-30.

PMID:
    18936500
    [PubMed - indexed for MEDLINE]
Related citations


The impact of induction on survival after lung transplantation: an analysis of the International Society for Heart and Lung Transplantation Registry.
Hachem RR, Edwards LB, Yusen RD, Chakinala MM, Alexander Patterson G, Trulock EP
Clin Transplant. 2008 Sep-Oct; 22(5)603-8. doi: 10.1111/j.1399-0012.2008.00831.x.

PMID:
    18435784
    [PubMed - indexed for MEDLINE]
Related citations


Medical therapy for pulmonary arterial hypertension.
Driscoll JA, Chakinala MM
Expert Opin Pharmacother. 2008 Jan; 9(1)65-81.

PMID:
    18076339
    [PubMed - indexed for MEDLINE]
Related citations


A randomized controlled trial of tacrolimus versus cyclosporine after lung transplantation.
Hachem RR, Yusen RD, Chakinala MM, Meyers BF, Lynch JP, Aloush AA, Patterson GA, Trulock EP
J Heart Lung Transplant. 2007 Oct; 26(10)1012-8.

PMID:
    17919621
    [PubMed - indexed for MEDLINE]
Related citations


Impact of immediate primary lung allograft dysfunction on bronchiolitis obliterans syndrome.
Daud SA, Yusen RD, Meyers BF, Chakinala MM, Walter MJ, Aloush AA, Patterson GA, Trulock EP, Hachem RR
Am J Respir Crit Care Med. 2007 Mar 1; 175(5)507-13.

PMID:
    17158279
    [PubMed - indexed for MEDLINE]
Related citations


IL-12 p80 is an innate epithelial cell effector that mediates chronic allograft dysfunction.
Mikols CL, Yan L, Norris JY, Russell TD, Khalifah AP, Hachem RR, Chakinala MM, Yusen RD, Castro M, Kuo E, Patterson GA, Mohanakumar T, Trulock EP, Walter MJ
Am J Respir Crit Care Med. 2006 Aug 15; 174(4)461-70.

PMID:
    16728708
    [PubMed - indexed for MEDLINE]
Related citations

In the News

In the News

Murali Chakinala, MD

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2016.

Company Name: Bayer

Royalties:

Equity: No

Consulting/Advisory Board: $10,001 - $25,000

Speaker Fees: $10,001 - $25,000

Reporting Date: May 01, 2017