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Michael S. Diamond, MD, PhD

Herbert S. Gasser Professor of Medicine
Division of Infectious Diseases
Professor, Molecular Microbiology, Pathology and Immunology

Specialty Areas

Infectious Diseases

Board Certifications

Infectious Disease
Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

  • Education
  • Publication & Research

Education

Education

Research Fellowship: Department of Public Health, Infectious Disease Unit, University of California, Berkeley, California 2001
Clinical Fellowship: Infectious Disease, University of California, San Francisco, California 1998
Residency: Internal Medicine, University of California, San Francisco, California 1997
Research Fellowship: Molecular and Cell Biology, University of California, Berkeley, California 1995
Medical Degree: Harvard Medical School, Harvard University, Boston, Massachusetts 1994
Ph.D.: Cell and Developmental Biology, Graduate School of Arts and Sciences, Harvard University, Boston, Massachusetts 1994
B.A.: Political Science, Columbia College of Columbia University, New York, New York 1985

Publication & Research

Publication & Research

Sufficiency of CD40 activation and immune checkpoint blockade for T cell priming and tumor immunity.
Morrison AH, Diamond MS, Hay CA, Byrne KT, Vonderheide RH
Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14)8022-8031. doi: 10.1073/pnas.1918971117.

PMID:
    32213589
    [PubMed - in process]
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Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response.
Ma H, Qian W, Bambouskova M, Collins PL, Porter SI, Byrum AK, Zhang R, Artyomov M, Oltz EM, Mosammaparast N, Miner JJ, Diamond MS
mBio. 2020 Mar 10; 11(2)pii: e00136-20. doi: 10.1128/mBio.00136-20.

PMID:
    32156810
    [PubMed - in process]
Related citations


Chikungunya virus evades antiviral CD8<sup>+</sup> T cell responses to establish persistent infection in joint-associated tissues.
Davenport BJ, Bullock C, McCarthy MK, Hawman DW, Murphy KM, Kedl RM, Diamond MS, Morrison TE
J Virol. 2020 Feb 26; pii: JVI.02036-19. doi: 10.1128/JVI.02036-19.

PMID:
    32102875
    [PubMed - as supplied by publisher]
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An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis.
Kim AS, Zimmerman O, Fox JM, Nelson CA, Basore K, Zhang R, Durnell L, Desai C, Bullock C, Deem SL, Oppenheimer J, Shapiro B, Wang T, Cherry S, Coyne CB, Handley SA, Landis MJ, Fremont DH, Diamond MS
Cell Host Microbe. 2020 Mar 11; 27(3)428-440.e9. doi: 10.1016/j.chom.2020.01.008.

PMID:
    32075743
    [PubMed - indexed for MEDLINE]
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Author Correction: Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection.
Fernandez E, Dejnirattisai W, Cao B, Scheaffer SM, Supasa P, Wongwiwat W, Esakky P, Drury A, Mongkolsapaya J, Moley KH, Mysorekar IU, Screaton GR, Diamond MS
Nat Immunol. 2020 Mar; 21(3)354. doi: 10.1038/s41590-019-0560-5.

PMID:
    32001822
    [PubMed]
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MyD88-dependent influx of monocytes and neutrophils impairs lymph node B cell responses to chikungunya virus infection via Irf5, Nos2 and Nox2.
McCarthy MK, Reynoso GV, Winkler ES, Mack M, Diamond MS, Hickman HD, Morrison TE
PLoS Pathog. 2020 Jan; 16(1)e1008292. doi: 10.1371/journal.ppat.1008292.

PMID:
    31999809
    [PubMed - in process]
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Immune correlates of tuberculosis disease and risk translate across species.
Ahmed M, Thirunavukkarasu S, Rosa BA, Thomas KA, Das S, Rangel-Moreno J, Lu L, Mehra S, Mbandi SK, Thackray LB, Diamond MS, Murphy KM, Means T, Martin J, Kaushal D, Scriba TJ, Mitreva M, Khader SA
Sci Transl Med. 2020 Jan 29; 12(528)pii: eaay0233. doi: 10.1126/scitranslmed.aay0233.

PMID:
    31996462
    [PubMed - in process]
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Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin α<sub>v</sub>β<sub>5</sub> Axis.
Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, Weis SM, Mack SC, Negraes PD, Trujillo CA, Penalva LO, Feng J, Lan Z, Zhang R, Wessel AW, Dhawan S, Diamond MS, Chen CC, Wechsler-Reya RJ, Gage FH, Hu H, Siqueira-Neto JL, Muotri AR, Cheresh DA, Rich JN
Cell Stem Cell. 2020 Feb 6; 26(2)187-204.e10. doi: 10.1016/j.stem.2019.11.016.

PMID:
    31956038
    [PubMed - in process]
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GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 5: Entomological aspects.
Pezzi L, Diallo M, Rosa-Freitas MG, Vega-Rua A, Ng LFP, Boyer S, Drexler JF, Vasilakis N, Lourenco-de-Oliveira R, Weaver SC, Kohl A, de Lamballerie X, Failloux AB, GloPID-R chikungunya, o'nyong-nyong and Mayaro virus Working Group.
Antiviral Res. 2020 Feb; 174104670. doi: 10.1016/j.antiviral.2019.104670.

PMID:
    31812638
    [PubMed - in process]
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Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge.
Zhao H, Xu L, Bombardi R, Nargi R, Deng Z, Errico JM, Nelson CA, Dowd KA, Pierson TC, Crowe JE, Diamond MS, Fremont DH
J Exp Med. 2020 Feb 3; 217(2)pii: e20191792. doi: 10.1084/jem.20191792.

PMID:
    31757867
    [PubMed - in process]
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Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins.
Quiroz JA, Malonis RJ, Thackray LB, Cohen CA, Pallesen J, Jangra RK, Brown RS, Hofmann D, Holtsberg FW, Shulenin S, Nyakatura EK, Durnell LA, Rayannavar V, Daily JP, Ward AB, Aman MJ, Dye JM, Chandran K, Diamond MS, Kielian M, Lai JR
PLoS Pathog. 2019 Nov; 15(11)e1008061. doi: 10.1371/journal.ppat.1008061.

PMID:
    31697791
    [PubMed - indexed for MEDLINE]
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Distinct Roles of Interferon Alpha and Beta in Controlling Chikungunya Virus Replication and Modulating Neutrophil-Mediated Inflammation.
Cook LE, Locke MC, Young AR, Monte K, Hedberg ML, Shimak RM, Sheehan KCF, Veis DJ, Diamond MS, Lenschow DJ
J Virol. 2019 Dec 12; 94(1)pii: e00841-19. doi: 10.1128/JVI.00841-19.

PMID:
    31619554
    [PubMed - in process]
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Zika Virus Causes Acute and Chronic Prostatitis in Mice and Macaques.
Halabi J, Jagger BW, Salazar V, Winkler ES, White JP, Humphrey PA, Hirsch AJ, Streblow DN, Diamond MS, Moley K
J Infect Dis. 2020 Apr 7; 221(9)1506-1517. doi: 10.1093/infdis/jiz533.

PMID:
    31616920
    [PubMed - in process]
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Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity.
Riedl W, Acharya D, Lee JH, Liu G, Serman T, Chiang C, Chan YK, Diamond MS, Gack MU
Cell Host Microbe. 2019 Oct 9; 26(4)493-503.e6. doi: 10.1016/j.chom.2019.09.012.

PMID:
    31600501
    [PubMed - indexed for MEDLINE]
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Clearance of Chikungunya Virus Infection in Lymphoid Tissues Is Promoted by Treatment with an Agonistic Anti-CD137 Antibody.
Hong JP, McCarthy MK, Davenport BJ, Morrison TE, Diamond MS
J Virol. 2019 Dec 15; 93(24)pii: e01231-19. doi: 10.1128/JVI.01231-19.

PMID:
    31578287
    [PubMed - in process]
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GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus.
Pezzi L, LaBeaud AD, Reusken CB, Drexler JF, Vasilakis N, Diallo M, Simon F, Jaenisch T, Gallian P, Sall A, Failloux AB, Weaver SC, de Lamballerie X, GloPID-R chikungunya, o'nyong-nyong and Mayaro virus Working Group.
Antiviral Res. 2019 Dec; 172104611. doi: 10.1016/j.antiviral.2019.104611.

PMID:
    31545982
    [PubMed - in process]
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GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 3: Epidemiological distribution of Mayaro virus.
Pezzi L, Rodriguez-Morales AJ, Reusken CB, Ribeiro GS, LaBeaud AD, Lourenço-de-Oliveira R, Brasil P, Lecuit M, Failloux AB, Gallian P, Jaenisch T, Simon F, Siqueira AM, Rosa-Freitas MG, Vega Rua A, Weaver SC, Drexler JF, Vasilakis N, de Lamballerie X, GloPID-R chikungunya, o'nyong-nyong and Mayaro virus Working Group.
Antiviral Res. 2019 Dec; 172104610. doi: 10.1016/j.antiviral.2019.104610.

PMID:
    31545981
    [PubMed - in process]
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Mechanisms of Pathogen Invasion into the Central Nervous System.
Cain MD, Salimi H, Diamond MS, Klein RS
Neuron. 2019 Sep 4; 103(5)771-783. doi: 10.1016/j.neuron.2019.07.015.

PMID:
    31487528
    [PubMed - indexed for MEDLINE]
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Expression of the Mxra8 Receptor Promotes Alphavirus Infection and Pathogenesis in Mice and Drosophila.
Zhang R, Earnest JT, Kim AS, Winkler ES, Desai P, Adams LJ, Hu G, Bullock C, Gold B, Cherry S, Diamond MS
Cell Rep. 2019 Sep 3; 28(10)2647-2658.e5. doi: 10.1016/j.celrep.2019.07.105.

PMID:
    31484075
    [PubMed - in process]
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A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy.
Hassan AO, Dmitriev IP, Kashentseva EA, Zhao H, Brough DE, Fremont DH, Curiel DT, Diamond MS
Cell Rep. 2019 Sep 3; 28(10)2634-2646.e4. doi: 10.1016/j.celrep.2019.08.005.

PMID:
    31484074
    [PubMed - in process]
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Areas of Research Interest

West Nile virus, Dengue virus, Chikungunya virus, antibody immunity, interferon immunity