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Michael S. Diamond, MD, PhD

Herbert S. Gasser Professor of Medicine
Division of Infectious Diseases
Professor, Molecular Microbiology, Pathology and Immunology

Specialty Areas

Infectious Diseases

Board Certifications

Infectious Disease
Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

  • Education
  • Publication & Research

Education

Education

Research Fellowship: Department of Public Health, Infectious Disease Unit, University of California, Berkeley, California 2001
Clinical Fellowship: Infectious Disease, University of California, San Francisco, California 1998
Residency: Internal Medicine, University of California, San Francisco, California 1997
Research Fellowship: Molecular and Cell Biology, University of California, Berkeley, California 1995
Medical Degree: Harvard Medical School, Harvard University, Boston, Massachusetts 1994
Ph.D.: Cell and Developmental Biology, Graduate School of Arts and Sciences, Harvard University, Boston, Massachusetts 1994
B.A.: Political Science, Columbia College of Columbia University, New York, New York 1985

Publication & Research

Publication & Research

Correction: Zika virus has oncolytic activity against glioblastoma stem cells.
Zhu Z, Gorman MJ, McKenzie LD, Chai JN, Hubert CG, Prager BC, Fernandez E, Richner JM, Zhang R, Shan C, Tycksen E, Wang X, Shi PY, Diamond MS, Rich JN, Chheda MG
J Exp Med. 2017 Sep 15; pii: jem.2017109309122017c. doi: 10.1084/jem.2017109309122017c.

PMID:
    28916645
    [PubMed - as supplied by publisher]
Related citations


Gestational Stage and IFN-λ Signaling Regulate ZIKV Infection In Utero.
Jagger BW, Miner JJ, Cao B, Arora N, Smith AM, Kovacs A, Mysorekar IU, Coyne CB, Diamond MS
Cell Host Microbe. 2017 Sep 13; 22(3)366-376.e3. doi: 10.1016/j.chom.2017.08.012.

PMID:
    28910635
    [PubMed - in process]
Related citations


Zika virus has oncolytic activity against glioblastoma stem cells.
Zhu Z, Gorman MJ, McKenzie LD, Chai JN, Hubert CG, Prager BC, Fernandez E, Richner JM, Zhang R, Shan C, Tycksen E, Wang X, Shi PY, Diamond MS, Rich JN, Chheda MG
J Exp Med. 2017 Sep 5; pii: jem.20171093. doi: 10.1084/jem.20171093.

PMID:
    28874392
    [PubMed - as supplied by publisher]
Related citations


Interferon regulatory factor-1 (IRF-1) protects against chikungunya virus induced immunopathology by restricting infection in muscle cells.
Nair S, Poddar S, Shimak RM, Diamond MS
J Virol. 2017 Aug 23; pii: JVI.01419-17. doi: 10.1128/JVI.01419-17.

PMID:
    28835505
    [PubMed - as supplied by publisher]
Related citations


Immune correlates of protection for dengue: State of the art and research agenda.
Katzelnick LC, Harris E, Participants in the Summit on Dengue Immune Correlates of Protection.
Vaccine. 2017 Aug 24; 35(36)4659-4669. doi: 10.1016/j.vaccine.2017.07.045.

PMID:
    28757058
    [PubMed - in process]
Related citations


MUTATIONS IN THE E2 GLYCOPROTEIN AND THE 3' UNTRANSLATED REGION ENHANCE CHIKUNGUNYA VIRUS VIRULENCE IN MICE.
Hawman DW, Carpentier KS, Fox JM, May NA, Sanders W, Montgomery SA, Moorman NJ, Diamond MS, Morrison TE
J Virol. 2017 Jul 26; pii: JVI.00816-17. doi: 10.1128/JVI.00816-17.

PMID:
    28747508
    [PubMed - as supplied by publisher]
Related citations


Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease.
Richner JM, Jagger BW, Shan C, Fontes CR, Dowd KA, Cao B, Himansu S, Caine EA, Nunes BTD, Medeiros DBA, Muruato AE, Foreman BM, Luo H, Wang T, Barrett AD, Weaver SC, Vasconcelos PFC, Rossi SL, Ciaramella G, Mysorekar IU, Pierson TC, Shi PY, Diamond MS
Cell. 2017 Jul 13; 170(2)273-283.e12. doi: 10.1016/j.cell.2017.06.040.

PMID:
    28708997
    [PubMed - indexed for MEDLINE]
Related citations


Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice.
Cao B, Parnell LA, Diamond MS, Mysorekar IU
J Exp Med. 2017 Aug 7; 214(8)2303-2313. doi: 10.1084/jem.20170957.

PMID:
    28694387
    [PubMed - in process]
Related citations


Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques.
Broeckel R, Fox JM, Haese N, Kreklywich CN, Sukulpovi-Petty S, Legasse A, Smith PP, Denton M, Corvey C, Krishnan S, Colgin LMA, Ducore RM, Lewis AD, Axthelm MK, Mandron M, Cortez P, Rothblatt J, Rao E, Focken I, Carter K, Sapparapau G, Crowe JE Jr, Diamond MS, Streblow DN
PLoS Negl Trop Dis. 2017 Jun; 11(6)e0005637. doi: 10.1371/journal.pntd.0005637.

PMID:
    28628616
    [PubMed - indexed for MEDLINE]
Related citations


Dengue Antibodies, then Zika: A Fatal Sequence in Mice.
Miner JJ, Diamond MS
Immunity. 2017 May 16; 46(5)771-773. doi: 10.1016/j.immuni.2017.04.023.

PMID:
    28514683
    [PubMed - in process]
Related citations


Plasmodium falciparum histidine-rich protein II causes vascular leakage and exacerbates experimental cerebral malaria in mice.
Pal P, Balaban AE, Diamond MS, Sinnis P, Klein RS, Goldberg DE
PLoS One. 2017; 12(5)e0177142. doi: 10.1371/journal.pone.0177142.

PMID:
    28475625
    [PubMed - indexed for MEDLINE]
Related citations


Vaccination strategies against Zika virus.
Fernandez E, Diamond MS
Curr Opin Virol. 2017 Apr; 2359-67. doi: 10.1016/j.coviro.2017.03.006.

PMID:
    28432975
    [PubMed - in process]
Related citations


TAM Receptors Are Not Required for Zika Virus Infection in Mice.
Hastings AK, Yockey LJ, Jagger BW, Hwang J, Uraki R, Gaitsch HF, Parnell LA, Cao B, Mysorekar IU, Rothlin CV, Fikrig E, Diamond MS, Iwasaki A
Cell Rep. 2017 Apr 18; 19(3)558-568. doi: 10.1016/j.celrep.2017.03.058.

PMID:
    28423319
    [PubMed - indexed for MEDLINE]
Related citations


Maternal-Fetal Transmission of Zika Virus: Routes and Signals for Infection.
Cao B, Diamond MS, Mysorekar IU
J Interferon Cytokine Res. 2017 Jul; 37(7)287-294. doi: 10.1089/jir.2017.0011.

PMID:
    28402153
    [PubMed - in process]
Related citations


Modified mRNA Vaccines Protect against Zika Virus Infection.
Richner JM, Himansu S, Dowd KA, Butler SL, Salazar V, Fox JM, Julander JG, Tang WW, Shresta S, Pierson TC, Ciaramella G, Diamond MS
Cell. 2017 Mar 23; 169(1)176. doi: 10.1016/j.cell.2017.03.016.

PMID:
    28340344
    [PubMed - in process]
Related citations


A human antibody against Zika virus crosslinks the E protein to prevent infection.
Hasan SS, Miller A, Sapparapu G, Fernandez E, Klose T, Long F, Fokine A, Porta JC, Jiang W, Diamond MS, Crowe JE Jr, Kuhn RJ, Rossmann MG
Nat Commun. 2017 Mar 16; 814722. doi: 10.1038/ncomms14722.

PMID:
    28300075
    [PubMed - in process]
Related citations


Negative regulators of the RIG-I-like receptor signaling pathway.
Quicke KM, Diamond MS, Suthar MS
Eur J Immunol. 2017 Apr; 47(4)615-628. doi: 10.1002/eji.201646484.

PMID:
    28295214
    [PubMed - indexed for MEDLINE]
Related citations


Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects.
Bekerman E, Neveu G, Shulla A, Brannan J, Pu SY, Wang S, Xiao F, Barouch-Bentov R, Bakken RR, Mateo R, Govero J, Nagamine CM, Diamond MS, De Jonghe S, Herdewijn P, Dye JM, Randall G, Einav S
J Clin Invest. 2017 Apr 3; 127(4)1338-1352. doi: 10.1172/JCI89857.

PMID:
    28240606
    [PubMed - indexed for MEDLINE]
Related citations


Modified mRNA Vaccines Protect against Zika Virus Infection.
Richner JM, Himansu S, Dowd KA, Butler SL, Salazar V, Fox JM, Julander JG, Tang WW, Shresta S, Pierson TC, Ciaramella G, Diamond MS
Cell. 2017 Mar 9; 168(6)1114-1125.e10. doi: 10.1016/j.cell.2017.02.017.

PMID:
    28222903
    [PubMed - indexed for MEDLINE]
Related citations


A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis.
Goo L, VanBlargan LA, Dowd KA, Diamond MS, Pierson TC
PLoS Pathog. 2017 Feb; 13(2)e1006178. doi: 10.1371/journal.ppat.1006178.

PMID:
    28207910
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

West Nile virus, Dengue virus, Chikungunya virus, antibody immunity, interferon immunity