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Michael S. Diamond, MD, PhD

Herbert S. Gasser Professor of Medicine
Division of Infectious Diseases
Professor, Molecular Microbiology, Pathology and Immunology

Specialty Areas

Infectious Diseases

Board Certifications

Infectious Disease
Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

  • Education
  • Publication & Research

Education

Education

Research Fellowship: Department of Public Health, Infectious Disease Unit, University of California, Berkeley, California 2001
Clinical Fellowship: Infectious Disease, University of California, San Francisco, California 1998
Residency: Internal Medicine, University of California, San Francisco, California 1997
Research Fellowship: Molecular and Cell Biology, University of California, Berkeley, California 1995
Medical Degree: Harvard Medical School, Harvard University, Boston, Massachusetts 1994
Ph.D.: Cell and Developmental Biology, Graduate School of Arts and Sciences, Harvard University, Boston, Massachusetts 1994
B.A.: Political Science, Columbia College of Columbia University, New York, New York 1985

Publication & Research

Publication & Research

Distinct roles of interferon alpha and beta in controlling chikungunya virus replication and modulating neutrophil-mediated inflammation.
Cook LE, Locke MC, Young AR, Monte K, Hedberg ML, Shimak RM, Sheehan KCF, Veis DJ, Diamond MS, Lenschow DJ
J Virol. 2019 Oct 16; pii: JVI.00841-19. doi: 10.1128/JVI.00841-19.

PMID:
    31619554
    [PubMed - as supplied by publisher]
Related citations


Zika virus causes acute and chronic prostatitis in mice and macaques.
Halabi J, Jagger BW, Salazar V, Winkler ES, White JP, Humphrey PA, Hirsch AJ, Streblow DN, Diamond MS, Moley K
J Infect Dis. 2019 Oct 16; pii: jiz533. doi: 10.1093/infdis/jiz533.

PMID:
    31616920
    [PubMed - as supplied by publisher]
Related citations


Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity.
Riedl W, Acharya D, Lee JH, Liu G, Serman T, Chiang C, Chan YK, Diamond MS, Gack MU
Cell Host Microbe. 2019 Oct 9; 26(4)493-503.e6. doi: 10.1016/j.chom.2019.09.012.

PMID:
    31600501
    [PubMed - in process]
Related citations


Clearance of Chikungunya virus infection in lymphoid tissues is promoted by treatment with an agonistic anti-CD137 antibody.
Hong JP, McCarthy MK, Davenport BJ, Morrison TE, Diamond MS
J Virol. 2019 Oct 2; pii: JVI.01231-19. doi: 10.1128/JVI.01231-19.

PMID:
    31578287
    [PubMed - as supplied by publisher]
Related citations


GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus.
Pezzi L, LaBeaud AD, Reusken CB, Drexler JF, Vasilakis N, Diallo M, Simon F, Jaenisch T, Gallian P, Sall A, Failloux AB, Weaver SC, de Lamballerie X, GloPID-R chikungunya, o'nyong-nyong and Mayaro virus Working Group.
Antiviral Res. 2019 Sep 20; 172104611. doi: 10.1016/j.antiviral.2019.104611.

PMID:
    31545982
    [PubMed - as supplied by publisher]
Related citations


GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 3: Epidemiological distribution of Mayaro virus.
Pezzi L, Rodriguez-Morales AJ, Reusken CB, Ribeiro GS, LaBeaud AD, Lourenço-de-Oliveira R, Brasil P, Lecuit M, Failloux AB, Gallian P, Jaenisch T, Simon F, Siqueira AM, Rosa-Freitas MG, Vega Rua A, Weaver SC, Drexler JF, Vasilakis N, de Lamballerie X, GloPID-R chikungunya, o'nyong-nyong and Mayaro virus Working Group.
Antiviral Res. 2019 Sep 20; 172104610. doi: 10.1016/j.antiviral.2019.104610.

PMID:
    31545981
    [PubMed - as supplied by publisher]
Related citations


Mechanisms of Pathogen Invasion into the Central Nervous System.
Cain MD, Salimi H, Diamond MS, Klein RS
Neuron. 2019 Sep 4; 103(5)771-783. doi: 10.1016/j.neuron.2019.07.015.

PMID:
    31487528
    [PubMed - in process]
Related citations


Expression of the Mxra8 Receptor Promotes Alphavirus Infection and Pathogenesis in Mice and Drosophila.
Zhang R, Earnest JT, Kim AS, Winkler ES, Desai P, Adams LJ, Hu G, Bullock C, Gold B, Cherry S, Diamond MS
Cell Rep. 2019 Sep 3; 28(10)2647-2658.e5. doi: 10.1016/j.celrep.2019.07.105.

PMID:
    31484075
    [PubMed - in process]
Related citations


A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy.
Hassan AO, Dmitriev IP, Kashentseva EA, Zhao H, Brough DE, Fremont DH, Curiel DT, Diamond MS
Cell Rep. 2019 Sep 3; 28(10)2634-2646.e4. doi: 10.1016/j.celrep.2019.08.005.

PMID:
    31484074
    [PubMed - in process]
Related citations


A protective Zika virus E-dimer-based subunit vaccine engineered to abrogate antibody-dependent enhancement of dengue infection.
Slon-Campos JL, Dejnirattisai W, Jagger BW, López-Camacho C, Wongwiwat W, Durnell LA, Winkler ES, Chen RE, Reyes-Sandoval A, Rey FA, Diamond MS, Mongkolsapaya J, Screaton GR
Nat Immunol. 2019 Oct; 20(10)1291-1298. doi: 10.1038/s41590-019-0477-z.

PMID:
    31477918
    [PubMed - in process]
Related citations


Dermal and muscle fibroblasts and skeletal myofibers survive chikungunya virus infection and harbor persistent RNA.
Young AR, Locke MC, Cook LE, Hiller BE, Zhang R, Hedberg ML, Monte KJ, Veis DJ, Diamond MS, Lenschow DJ
PLoS Pathog. 2019 Aug; 15(8)e1007993. doi: 10.1371/journal.ppat.1007993.

PMID:
    31465513
    [PubMed - in process]
Related citations


Neutralizing antibodies against Mayaro virus require Fc effector functions for protective activity.
Earnest JT, Basore K, Roy V, Bailey AL, Wang D, Alter G, Fremont DH, Diamond MS
J Exp Med. 2019 Oct 7; 216(10)2282-2301. doi: 10.1084/jem.20190736.

PMID:
    31337735
    [PubMed - in process]
Related citations


Protective Efficacy of Nucleic Acid Vaccines Against Transmission of Zika Virus During Pregnancy in Mice.
Jagger BW, Dowd KA, Chen RE, Desai P, Foreman B, Burgomaster KE, Himansu S, Kong WP, Graham BS, Pierson TC, Diamond MS
J Infect Dis. 2019 Oct 8; 220(10)1577-1588. doi: 10.1093/infdis/jiz338.

PMID:
    31260518
    [PubMed - in process]
Related citations


No IL-18BP? Avoid HAV.
Diamond MS
J Exp Med. 2019 Aug 5; 216(8)1728-1729. doi: 10.1084/jem.20190841.

PMID:
    31243052
    [PubMed - in process]
Related citations


Therapeutic efficacy of favipiravir against Bourbon virus in mice.
Bricker TL, Shafiuddin M, Gounder AP, Janowski AB, Zhao G, Williams GD, Jagger BW, Diamond MS, Bailey T, Kwon JH, Wang D, Boon ACM
PLoS Pathog. 2019 Jun; 15(6)e1007790. doi: 10.1371/journal.ppat.1007790.

PMID:
    31194854
    [PubMed - in process]
Related citations


A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection.
Kose N, Fox JM, Sapparapu G, Bombardi R, Tennekoon RN, de Silva AD, Elbashir SM, Theisen MA, Humphris-Narayanan E, Ciaramella G, Himansu S, Diamond MS, Crowe JE Jr
Sci Immunol. 2019 May 17; 4(35)pii: eaaw6647. doi: 10.1126/sciimmunol.aaw6647.

PMID:
    31101672
    [PubMed - in process]
Related citations


Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Basore K, Kim AS, Nelson CA, Zhang R, Smith BK, Uranga C, Vang L, Cheng M, Gross ML, Smith J, Diamond MS, Fremont DH
Cell. 2019 Jun 13; 177(7)1725-1737.e16. doi: 10.1016/j.cell.2019.04.006.

PMID:
    31080061
    [PubMed - in process]
Related citations


Zika virus causes acute infection and inflammation in the ovary of mice without apparent defects in fertility.
Caine EA, Scheaffer SM, Broughton DE, Salazar V, Govero J, Poddar S, Osula A, Halabi J, Skaznik-Wikiel ME, Diamond MS, Moley KH
J Infect Dis. 2019 May 7; pii: jiz239. doi: 10.1093/infdis/jiz239.

PMID:
    31063544
    [PubMed - as supplied by publisher]
Related citations


Shared and Distinct Functions of Type I and Type III Interferons.
Lazear HM, Schoggins JW, Diamond MS
Immunity. 2019 Apr 16; 50(4)907-923. doi: 10.1016/j.immuni.2019.03.025.

PMID:
    30995506
    [PubMed - indexed for MEDLINE]
Related citations


GloPID-R report on Chikungunya, O'nyong-nyong and Mayaro virus, part I: Biological diagnostics.
Pezzi L, Reusken CB, Weaver SC, Drexler JF, Busch M, LaBeaud AD, Diamond MS, Vasilakis N, Drebot MA, Siqueira AM, Ribeiro GS, Kohl A, Lecuit M, Ng LFP, Gallian P, de Lamballerie X, GloPID-R Chikungunya, O'nyong-nyong and Mayaro virus Working Group.
Antiviral Res. 2019 Jun; 16666-81. doi: 10.1016/j.antiviral.2019.03.009.

PMID:
    30905821
    [PubMed - in process]
Related citations

Areas of Research Interest

West Nile virus, Dengue virus, Chikungunya virus, antibody immunity, interferon immunity