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Michael S. Diamond, MD, PhD

Herbert S. Gasser Professor of Medicine
Division of Infectious Diseases
Professor, Molecular Microbiology, Pathology and Immunology

Specialty Areas

Infectious Diseases

Board Certifications

Infectious Disease
Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

  • Education
  • Publication & Research

Education

Education

Research Fellowship: Department of Public Health, Infectious Disease Unit, University of California, Berkeley, California 2001
Clinical Fellowship: Infectious Disease, University of California, San Francisco, California 1998
Residency: Internal Medicine, University of California, San Francisco, California 1997
Research Fellowship: Molecular and Cell Biology, University of California, Berkeley, California 1995
Medical Degree: Harvard Medical School, Harvard University, Boston, Massachusetts 1994
Ph.D.: Cell and Developmental Biology, Graduate School of Arts and Sciences, Harvard University, Boston, Massachusetts 1994
B.A.: Political Science, Columbia College of Columbia University, New York, New York 1985

Publication & Research

Publication & Research

Therapeutic efficacy of favipiravir against Bourbon virus in mice.
Bricker TL, Shafiuddin M, Gounder AP, Janowski AB, Zhao G, Williams GD, Jagger BW, Diamond MS, Bailey T, Kwon JH, Wang D, Boon ACM
PLoS Pathog. 2019 Jun; 15(6)e1007790. doi: 10.1371/journal.ppat.1007790.

PMID:
    31194854
    [PubMed - in process]
Related citations


A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection.
Kose N, Fox JM, Sapparapu G, Bombardi R, Tennekoon RN, de Silva AD, Elbashir SM, Theisen MA, Humphris-Narayanan E, Ciaramella G, Himansu S, Diamond MS, Crowe JE Jr
Sci Immunol. 2019 May 17; 4(35)pii: eaaw6647. doi: 10.1126/sciimmunol.aaw6647.

PMID:
    31101672
    [PubMed - in process]
Related citations


Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Basore K, Kim AS, Nelson CA, Zhang R, Smith BK, Uranga C, Vang L, Cheng M, Gross ML, Smith J, Diamond MS, Fremont DH
Cell. 2019 Jun 13; 177(7)1725-1737.e16. doi: 10.1016/j.cell.2019.04.006.

PMID:
    31080061
    [PubMed - in process]
Related citations


Zika virus causes acute infection and inflammation in the ovary of mice without apparent defects in fertility.
Caine EA, Scheaffer SM, Broughton DE, Salazar V, Govero J, Poddar S, Osula A, Halabi J, Skaznik-Wikiel ME, Diamond MS, Moley KH
J Infect Dis. 2019 May 7; pii: jiz239. doi: 10.1093/infdis/jiz239.

PMID:
    31063544
    [PubMed - as supplied by publisher]
Related citations


Shared and Distinct Functions of Type I and Type III Interferons.
Lazear HM, Schoggins JW, Diamond MS
Immunity. 2019 Apr 16; 50(4)907-923. doi: 10.1016/j.immuni.2019.03.025.

PMID:
    30995506
    [PubMed - in process]
Related citations


GloPID-R report on Chikungunya, O'nyong-nyong and Mayaro virus, part I: Biological diagnostics.
Pezzi L, Reusken CB, Weaver SC, Drexler JF, Busch M, LaBeaud AD, Diamond MS, Vasilakis N, Drebot MA, Siqueira AM, Ribeiro GS, Kohl A, Lecuit M, Ng LFP, Gallian P, de Lamballerie X, GloPID-R Chikungunya, O'nyong-nyong and Mayaro virus Working Group.
Antiviral Res. 2019 Jun; 16666-81. doi: 10.1016/j.antiviral.2019.03.009.

PMID:
    30905821
    [PubMed - in process]
Related citations


Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes.
Fox JM, Roy V, Gunn BM, Huang L, Edeling MA, Mack M, Fremont DH, Doranz BJ, Johnson S, Alter G, Diamond MS
Sci Immunol. 2019 Feb 22; 4(32)pii: eaav5062. doi: 10.1126/sciimmunol.aav5062.

PMID:
    30796092
    [PubMed - in process]
Related citations


Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice.
Salazar V, Jagger BW, Mongkolsapaya J, Burgomaster KE, Dejnirattisai W, Winkler ES, Fernandez E, Nelson CA, Fremont DH, Pierson TC, Crowe JE Jr, Screaton GR, Diamond MS
Cell Rep. 2019 Feb 5; 26(6)1585-1597.e4. doi: 10.1016/j.celrep.2019.01.052.

PMID:
    30726740
    [PubMed - in process]
Related citations


Interferon lambda protects the female reproductive tract against Zika virus infection.
Caine EA, Scheaffer SM, Arora N, Zaitsev K, Artyomov MN, Coyne CB, Moley KH, Diamond MS
Nat Commun. 2019 Jan 17; 10(1)280. doi: 10.1038/s41467-018-07993-2.

PMID:
    30655513
    [PubMed - indexed for MEDLINE]
Related citations


Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope.
Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe JE Jr, Rossmann MG
Proc Natl Acad Sci U S A. 2019 Jan 29; 116(5)1591-1596. doi: 10.1073/pnas.1815432116.

PMID:
    30642974
    [PubMed - indexed for MEDLINE]
Related citations


Immune responses at the maternal-fetal interface.
Ander SE, Diamond MS, Coyne CB
Sci Immunol. 2019 Jan 11; 4(31)pii: eaat6114. doi: 10.1126/sciimmunol.aat6114.

PMID:
    30635356
    [PubMed - in process]
Related citations


Efficacy of a T Cell-Biased Adenovirus Vector as a Zika Virus Vaccine.
Bullard BL, Corder BN, Gorman MJ, Diamond MS, Weaver EA
Sci Rep. 2018 Dec 20; 8(1)18017. doi: 10.1038/s41598-018-35755-z.

PMID:
    30573745
    [PubMed - in process]
Related citations


An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections.
VanBlargan LA, Himansu S, Foreman BM, Ebel GD, Pierson TC, Diamond MS
Cell Rep. 2018 Dec 18; 25(12)3382-3392.e3. doi: 10.1016/j.celrep.2018.11.082.

PMID:
    30566864
    [PubMed - in process]
Related citations


Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG
Cell Rep. 2018 Dec 11; 25(11)3136-3147.e5. doi: 10.1016/j.celrep.2018.11.067.

PMID:
    30540945
    [PubMed - in process]
Related citations


A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions.
Goo L, Debbink K, Kose N, Sapparapu G, Doyle MP, Wessel AW, Richner JM, Burgomaster KE, Larman BC, Dowd KA, Diamond MS, Crowe JE Jr, Pierson TC
Nat Microbiol. 2019 Jan; 4(1)71-77. doi: 10.1038/s41564-018-0283-7.

PMID:
    30455471
    [PubMed - indexed for MEDLINE]
Related citations


Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein.
Kim AS, Austin SK, Gardner CL, Zuiani A, Reed DS, Trobaugh DW, Sun C, Basore K, Williamson LE, Crowe JE Jr, Slifka MK, Fremont DH, Klimstra WB, Diamond MS
Nat Microbiol. 2019 Jan; 4(1)187-197. doi: 10.1038/s41564-018-0286-4.

PMID:
    30455470
    [PubMed - indexed for MEDLINE]
Related citations


Maternally Acquired Zika Antibodies Enhance Dengue Disease Severity in Mice.
Fowler AM, Tang WW, Young MP, Mamidi A, Viramontes KM, McCauley MD, Carlin AF, Schooley RT, Swanstrom J, Baric RS, Govero J, Diamond MS, Shresta S
Cell Host Microbe. 2018 Nov 14; 24(5)743-750.e5. doi: 10.1016/j.chom.2018.09.015.

PMID:
    30439343
    [PubMed - in process]
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WDFY4 is required for cross-presentation in response to viral and tumor antigens.
Theisen DJ, Davidson JT 4th, Briseño CG, Gargaro M, Lauron EJ, Wang Q, Desai P, Durai V, Bagadia P, Brickner JR, Beatty WL, Virgin HW, Gillanders WE, Mosammaparast N, Diamond MS, Sibley LD, Yokoyama W, Schreiber RD, Murphy TL, Murphy KM
Science. 2018 Nov 9; 362(6415)694-699. doi: 10.1126/science.aat5030.

PMID:
    30409884
    [PubMed - indexed for MEDLINE]
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Zika Virus Vaccine Development: Progress in the Face of New Challenges.
Diamond MS, Ledgerwood JE, Pierson TC
Annu Rev Med. 2019 Jan 27; 70121-135. doi: 10.1146/annurev-med-040717-051127.

PMID:
    30388054
    [PubMed - in process]
Related citations


Animal Models of Zika Virus Infection during Pregnancy.
Caine EA, Jagger BW, Diamond MS
Viruses. 2018 Oct 31; 10(11)pii: E598. doi: 10.3390/v10110598.

PMID:
    30384472
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

West Nile virus, Dengue virus, Chikungunya virus, antibody immunity, interferon immunity