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Michael N. Diringer, MD

Professor, Neurology
Professor, Neurosurgery
Associate Professor, Anesthesiology
Associate Professor, Occupational Therapy

Specialty Areas

Neurology - Adult
Neurologic Intensive Care
Stroke
Cerebrovascular Disease

Board Certifications

Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

IN-PATIENT CARE ONLY in the Stroke Service. Neurology, hyponatremia, cerebral salt wasting, cerebral metabolism, subarachnoid hemorrhage, brain injury, brain imaging, head trauma, head injury, brain death, intracerebral hemorrhage, cerebral blood flow, neurologic critical care

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

Barnes-Jewish Hospital

1 Barnes-Jewish Hospital Plaza
St. Louis, MO 63110

Suite: Suite 10400
Office Phone: 314-362-2999
Fax: 314-362-0215
Email: diringerm@neuro.wustl.edu

Education

Education

Fellowship: Neurosciences Critical Care Fellow, Johns Hopkins University, Baltimore, Maryland 1988
Residency: Neurology, SUNY at Stony Brook, Stony Brook, New York 1985
Residency: Internal Medicine, SUNY at Stony Brook, Stony Brook, New York 1983
Medical Degree: University Of Kentucky , Kentucky 1982
B.A.: Psychology 1974

Publication & Research

Publication & Research

Nimodipine pharmacokinetics after intraventricular injection of sustained-release nimodipine for subarachnoid hemorrhage.
Macdonald RL, Hänggi D, Strange P, Steiger HJ, Mocco J, Miller M, Mayer SA, Hoh BL, Faleck HJ, Etminan N, Diringer MN, Carlson AP, Aldrich F, NEWTON Investigators.
J Neurosurg. 2019 Dec 6; 1-7. doi: 10.3171/2019.9.JNS191366.

PMID:
    31812149
    [PubMed - as supplied by publisher]
Related citations


The Future of Neurocritical Care Research: Proceedings and Recommendations from the Fifth Neurocritical Care Research Network Conference.
Hocker S, Shah S, Vespa P, Provencio JJ, Calvillo E, Olson DM, Venkatasubba Rao CP, Hemphill JC 3rd, Helbok R, Human T, Kamel H, Madden LK, Nyquist P, Bentho O, O'Phelan K, Lewin JJ 3rd, Alexander S, Ziai W, Chou SH, Rincon F, McNett M, Ko N, Zink B, Rhoney D, Diringer MN, Stevens R, Robertson CS, Sampaio G, Shutter LA, Ling G, Rehman M, Mahmoud SH, Yeager S, Livesay S, Suarez JI, attendees of the 5th Neurocritical Care Research Network Conference.
Neurocrit Care. 2019 Jul 1; doi: 10.1007/s12028-019-00767-8.

PMID:
    31264070
    [PubMed - as supplied by publisher]
Related citations


Burden of cerebral hypoperfusion in patients with delayed cerebral ischemia after subarachnoid hemorrhage.
Jafri H, Diringer MN, Allen M, Zazulia AR, Zipfel GJ, Dhar R
J Neurosurg. 2019 May 31; 1-8. doi: 10.3171/2019.3.JNS183041.

PMID:
    31151110
    [PubMed - as supplied by publisher]
Related citations


Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data.
Al-Shahi Salman R, Frantzias J, Lee RJ, Lyden PD, Battey TWK, Ayres AM, Goldstein JN, Mayer SA, Steiner T, Wang X, Arima H, Hasegawa H, Oishi M, Godoy DA, Masotti L, Dowlatshahi D, Rodriguez-Luna D, Molina CA, Jang DK, Davalos A, Castillo J, Yao X, Claassen J, Volbers B, Kazui S, Okada Y, Fujimoto S, Toyoda K, Li Q, Khoury J, Delgado P, Sabín JÁ, Hernández-Guillamon M, Prats-Sánchez L, Cai C, Kate MP, McCourt R, Venkatasubramanian C, Diringer MN, Ikeda Y, Worthmann H, Ziai WC, d'Esterre CD, Aviv RI, Raab P, Murai Y, Zazulia AR, Butcher KS, Seyedsaadat SM, Grotta JC, Martí-Fàbregas J, Montaner J, Broderick J, Yamamoto H, Staykov D, Connolly ES, Selim M, Leira R, Moon BH, Demchuk AM, Di Napoli M, Fujii Y, Anderson CS, Rosand J, VISTA-ICH Collaboration., ICH Growth Individual Patient Data Meta-analysis Collaborators.
Lancet Neurol. 2018 Oct; 17(10)885-894. doi: 10.1016/S1474-4422(18)30253-9.

PMID:
    30120039
    [PubMed - indexed for MEDLINE]
Related citations


The Interictal Continuum: Look Before You Leap.
Diringer MN
Neurocrit Care. 2018 Aug; 29(1)1-2. doi: 10.1007/s12028-018-0584-y.

PMID:
    30027348
    [PubMed - indexed for MEDLINE]
Related citations


Clinical Trial Protocol: Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy, and Safety Study Comparing EG-1962 to Standard of Care Oral Nimodipine in Adults with Aneurysmal Subarachnoid Hemorrhage [NEWTON-2 (Nimodipine Microparticles to Enhance Recovery While Reducing TOxicity After SubarachNoid Hemorrhage)].
Hänggi D, Etminan N, Mayer SA, Aldrich EF, Diringer MN, Schmutzhard E, Faleck HJ, Ng D, Saville BR, Macdonald RL, NEWTON Investigators.
Neurocrit Care. 2019 Feb; 30(1)88-97. doi: 10.1007/s12028-018-0575-z.

PMID:
    30014184
    [PubMed - in process]
Related citations


Will the Real Blood Pressure Please Stand Up?
Diringer MN
Neurocrit Care. 2018 Jun; 28(3)263-264. doi: 10.1007/s12028-018-0555-3.

PMID:
    29873024
    [PubMed - indexed for MEDLINE]
Related citations


Hemodynamic Therapy for Delayed Cerebral Ischemia in SAH.
Diringer MN
Neurocrit Care. 2018 Apr; 28(2)152-153. doi: 10.1007/s12028-018-0529-5.

PMID:
    29600342
    [PubMed - indexed for MEDLINE]
Related citations


Aneurysmal Subarachnoid Hemorrhage: Strategies for Preventing Vasospasm in the Intensive Care Unit.
Diringer MN, Zazulia AR
Semin Respir Crit Care Med. 2017 Dec; 38(6)760-767. doi: 10.1055/s-0037-1607990.

PMID:
    29262433
    [PubMed - indexed for MEDLINE]
Related citations


Can We Boost Our Ability to Monitor Severe Brain Trauma?
Diringer MN
Crit Care Med. 2017 Nov; 45(11)1961-1962. doi: 10.1097/CCM.0000000000002636.

PMID:
    29028705
    [PubMed - indexed for MEDLINE]
Related citations


A Randomized Trial of Brief Versus Extended Seizure Prophylaxis After Aneurysmal Subarachnoid Hemorrhage.
Human T, Diringer MN, Allen M, Zipfel GJ, Chicoine M, Dacey R, Dhar R
Neurocrit Care. 2018 Apr; 28(2)169-174. doi: 10.1007/s12028-017-0440-5.

PMID:
    28831717
    [PubMed - indexed for MEDLINE]
Related citations


The authors reply.
Diringer MN, Dhar R, Zazulia A
Crit Care Med. 2017 Sep; 45(9)e987-e988. doi: 10.1097/CCM.0000000000002532.

PMID:
    28816855
    [PubMed - indexed for MEDLINE]
Related citations


SANGUINATE™ (PEGylated Carboxyhemoglobin Bovine) Improves Cerebral Blood Flow to Vulnerable Brain Regions at Risk of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage.
Dhar R, Misra H, Diringer MN
Neurocrit Care. 2017 Dec; 27(3)341-349. doi: 10.1007/s12028-017-0418-3.

PMID:
    28639001
    [PubMed - indexed for MEDLINE]
Related citations


Are We Fortune Tellers or Healers?
Diringer MN
Crit Care Med. 2017 Apr; 45(4)751-752. doi: 10.1097/CCM.0000000000002280.

PMID:
    28291102
    [PubMed - indexed for MEDLINE]
Related citations


RBC Transfusion Improves Cerebral Oxygen Delivery in Subarachnoid Hemorrhage.
Dhar R, Zazulia AR, Derdeyn CP, Diringer MN
Crit Care Med. 2017 Apr; 45(4)653-659. doi: 10.1097/CCM.0000000000002266.

PMID:
    28169942
    [PubMed - indexed for MEDLINE]
Related citations


Randomized, Open-Label, Phase 1/2a Study to Determine the Maximum Tolerated Dose of Intraventricular Sustained Release Nimodipine for Subarachnoid Hemorrhage (NEWTON [Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage]).
Hänggi D, Etminan N, Aldrich F, Steiger HJ, Mayer SA, Diringer MN, Hoh BL, Mocco J, Faleck HJ, Macdonald RL, NEWTON Investigators.
Stroke. 2017 Jan; 48(1)145-151. doi: 10.1161/STROKEAHA.116.014250.

PMID:
    27932607
    [PubMed - indexed for MEDLINE]
Related citations


Decompressive Hemicraniectomy in the Age of Personalized Medicine.
Diringer MN
Neurocrit Care. 2016 Aug; 25(1)1-2. doi: 10.1007/s12028-016-0295-1.

PMID:
    27369872
    [PubMed - indexed for MEDLINE]
Related citations


Early Withdrawal Decision-Making in Patients with Coma After Cardiac Arrest: A Qualitative Study of Intensive Care Clinicians.
Ong CJ, Dhand A, Diringer MN
Neurocrit Care. 2016 Oct; 25(2)258-65. doi: 10.1007/s12028-016-0275-5.

PMID:
    27112149
    [PubMed - indexed for MEDLINE]
Related citations


Effect of High-Dose Simvastatin on Cerebral Blood Flow and Static Autoregulation in Subarachnoid Hemorrhage.
Diringer MN, Dhar R, Scalfani M, Zazulia AR, Chicoine M, Powers WJ, Derdeyn CP
Neurocrit Care. 2016 Aug; 25(1)56-63. doi: 10.1007/s12028-015-0233-7.

PMID:
    26721259
    [PubMed - indexed for MEDLINE]
Related citations


The Evolution of the Clinical Use of Osmotic Therapy in the Treatment of Cerebral Edema.
Diringer MN
Acta Neurochir Suppl. 2016; 1213-6. doi: 10.1007/978-3-319-18497-5_1.

PMID:
    26463914
    [PubMed - indexed for MEDLINE]
Related citations