Patient Portal

Meagan Anne Jacoby, MD

Instructor, Medicine
Division of Oncology
Section of Medical Oncology

Specialty Areas

Medical Oncology
Bone Marrow Transplant
Oncology
Hematology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Medical oncology, hematology

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Siteman Cancer Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 7
Office Phone: 314-454-8339

Education

Education

BA: Biology, The Johns Hopkin University, Baltimore, Maryland 1996
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 2005
PhD: Immunology, Washington University School of Medicine, St. Louis, Missouri 2005
Residency: Internal Medicine, Barnes-Jewish Hospital at Washington University School of Medicine, St. Louis, Missouri 2007
Fellowship: Hematology and Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 2011

Publication & Research

Publication & Research

Exome analysis of treatment-related AML after APL suggests secondary evolution.
Wang T, Jacoby MA, Duncavage EJ, Miller CA, Heath S, Rahme R, Fenaux P, Ades L, Renneville A, Cassinat B, Takeshita A, Asou N, Miyazaki Y, Kiyoi H, Ravandi F, Westervelt P, Wartman LD, Welch JS
Br J Haematol. 2018 Nov 22; doi: 10.1111/bjh.15681.

PMID:
    30467844
    [PubMed - as supplied by publisher]
Related citations


Mutation Clearance after Transplantation for Myelodysplastic Syndrome.
Duncavage EJ, Jacoby MA, Chang GS, Miller CA, Edwin N, Shao J, Elliott K, Robinson J, Abel H, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Brendel K, Saba R, Wartman LD, Christopher MJ, Pusic I, Welch JS, Uy GL, Link DC, DiPersio JF, Westervelt P, Ley TJ, Trinkaus K, Graubert TA, Walter MJ
N Engl J Med. 2018 Sep 13; 379(11)1028-1041. doi: 10.1056/NEJMoa1804714.

PMID:
    30207916
    [PubMed - indexed for MEDLINE]
Related citations


Subclones dominate at MDS progression following allogeneic hematopoietic cell transplant.
Jacoby MA, Duncavage EJ, Chang GS, Miller CA, Shao J, Elliott K, Robinson J, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Pusic I, Welch JS, Link DC, DiPersio JF, Westervelt P, Ley TJ, Graubert TA, Walter MJ
JCI Insight. 2018 Mar 8; 3(5)pii: 98962. doi: 10.1172/jci.insight.98962.

PMID:
    29515031
    [PubMed - as supplied by publisher]
Related citations


Patterns of infectious complications in acute myeloid leukemia and myelodysplastic syndromes patients treated with 10-day decitabine regimen.
Ali AM, Weisel D, Gao F, Uy GL, Cashen AF, Jacoby MA, Wartman LD, Ghobadi A, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Schroeder MA, Westervelt P, DiPersio JF, Welch JS
Cancer Med. 2017 Dec; 6(12)2814-2821. doi: 10.1002/cam4.1231.

PMID:
    29058375
    [PubMed - indexed for MEDLINE]
Related citations


A phase 1/2 study of chemosensitization with plerixafor plus G-CSF in relapsed or refractory acute myeloid leukemia.
Uy GL, Rettig MP, Stone RM, Konopleva MY, Andreeff M, McFarland K, Shannon W, Fletcher TR, Reineck T, Eades W, Stockerl-Goldstein K, Abboud CN, Jacoby MA, Westervelt P, DiPersio JF
Blood Cancer J. 2017 Mar 10; 7(3)e542. doi: 10.1038/bcj.2017.21.

PMID:
    28282031
    [PubMed - indexed for MEDLINE]
Related citations


Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy.
Duncavage EJ, Uy GL, Petti AA, Miller CA, Lee YS, Tandon B, Gao F, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Jacoby MA, Cashen AF, Wartman LD, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ, Welch JS
Blood. 2017 Mar 9; 129(10)1397-1401. doi: 10.1182/blood-2016-10-745273.

PMID:
    28082444
    [PubMed - indexed for MEDLINE]
Related citations


TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes.
Welch JS, Petti AA, Miller CA, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Baty JD, Duncavage EJ, Tandon B, Lee YS, Wartman LD, Uy GL, Ghobadi A, Tomasson MH, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Cashen AF, Schroeder MA, Jacoby MA, Heath SE, Luber K, Janke MR, Hantel A, Khan N, Sukhanova MJ, Knoebel RW, Stock W, Graubert TA, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ
N Engl J Med. 2016 Nov 24; 375(21)2023-2036. doi: 10.1056/NEJMoa1605949.

PMID:
    27959731
    [PubMed - indexed for MEDLINE]
Related citations


Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy.
Uy GL, Duncavage EJ, Chang GS, Jacoby MA, Miller CA, Shao J, Heath S, Elliott K, Reineck T, Fulton RS, Fronick CC, O'Laughlin M, Ganel L, Abboud CN, Cashen AF, DiPersio JF, Wilson RK, Link DC, Welch JS, Ley TJ, Graubert TA, Westervelt P, Walter MJ
Leukemia. 2017 Apr; 31(4)872-881. doi: 10.1038/leu.2016.282.

PMID:
    27740633
    [PubMed - indexed for MEDLINE]
Related citations


Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.
Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jódar E, Leiter LA, Lingvay I, Rosenstock J, Seufert J, Warren ML, Woo V, Hansen O, Holst AG, Pettersson J, Vilsbøll T, SUSTAIN-6 Investigators.
N Engl J Med. 2016 Nov 10; 375(19)1834-1844.

PMID:
    27633186
    [PubMed - indexed for MEDLINE]
Related citations


Targeted sequencing informs the evaluation of normal karyotype cytopenic patients for low-grade myelodysplastic syndrome.
Duncavage EJ, O'Brien J, Vij K, Miller CA, Chang GS, Shao J, Jacoby MA, Heath S, Janke MR, Elliott K, Fulton RS, Fronick C, O'Laughlin M, Westervelt P, Ley TJ, Wilson RK, Walter MJ
Leukemia. 2016 Dec; 30(12)2422-2426. doi: 10.1038/leu.2016.247.

PMID:
    27573557
    [PubMed - indexed for MEDLINE]
Related citations


A study of high-dose lenalidomide induction and low-dose lenalidomide maintenance therapy for patients with hypomethylating agent refractory myelodysplastic syndrome.
Cherian MA, Tibes R, Gao F, Fletcher T, Fiala M, Uy GL, Westervelt P, Jacoby MA, Cashen AF, Stockerl-Goldstein K, DiPersio JF, Vij R
Leuk Lymphoma. 2016 Nov; 57(11)2535-40. doi: 10.3109/10428194.2016.1173213.

PMID:
    27122296
    [PubMed - indexed for MEDLINE]
Related citations


A phase I study of carfilzomib for relapsed or refractory acute myeloid and acute lymphoblastic leukemia.
Wartman LD, Fiala MA, Fletcher T, Hawkins ER, Cashen A, DiPersio JF, Jacoby MA, Stockerl-Goldstein KE, Pusic I, Uy GL, Westervelt P, Vij R
Leuk Lymphoma. 2016; 57(3)728-30. doi: 10.3109/10428194.2015.1076930.

PMID:
    26674111
    [PubMed - indexed for MEDLINE]
Related citations


Implications of Tumor Clonal Heterogeneity in the Era of Next-Generation Sequencing.
Jacoby MA, Duncavage EJ, Walter MJ
Trends Cancer. 2015 Dec; 1(4)231-241. doi: 10.1016/j.trecan.2015.10.006.

PMID:
    28741514
    [PubMed]
Related citations


Maintenance Therapy with Decitabine after Allogeneic Stem Cell Transplantation for Acute Myelogenous Leukemia and Myelodysplastic Syndrome.
Pusic I, Choi J, Fiala MA, Gao F, Holt M, Cashen AF, Vij R, Abboud CN, Stockerl-Goldstein KE, Jacoby MA, Uy GL, Westervelt P, DiPersio JF
Biol Blood Marrow Transplant. 2015 Oct; 21(10)1761-9. doi: 10.1016/j.bbmt.2015.05.026.

PMID:
    26055299
    [PubMed - indexed for MEDLINE]
Related citations


Phase I study of oral clofarabine consolidation in adults aged 60 and older with acute myeloid leukemia.
Jacoby MA, Martin MG, Uy GL, Westervelt P, Dipersio JF, Cashen A, Stockerl-Goldstein K, Vij R, Luo J, Reineck T, Bernabe N, Abboud CN
Am J Hematol. 2014 May; 89(5)487-92. doi: 10.1002/ajh.23663.

PMID:
    24415560
    [PubMed - indexed for MEDLINE]
Related citations


The DNA double-strand break response is abnormal in myeloblasts from patients with therapy-related acute myeloid leukemia.
Jacoby MA, De Jesus Pizarro RE, Shao J, Koboldt DC, Fulton RS, Zhou G, Wilson RK, Walter MJ
Leukemia. 2014 Jun; 28(6)1242-51. doi: 10.1038/leu.2013.368.

PMID:
    24304937
    [PubMed - indexed for MEDLINE]
Related citations


Acquired copy number alterations of miRNA genes in acute myeloid leukemia are uncommon.
Ramsingh G, Jacoby MA, Shao J, De Jesus Pizzaro RE, Shen D, Trissal M, Getz AH, Ley TJ, Walter MJ, Link DC
Blood. 2013 Oct 10; 122(15)e44-51. doi: 10.1182/blood-2013-03-488007.

PMID:
    24009227
    [PubMed - indexed for MEDLINE]
Related citations


Detection of copy number alterations in acute myeloid leukemia and myelodysplastic syndromes.
Jacoby MA, Walter MJ
Expert Rev Mol Diagn. 2012 Apr; 12(3)253-64. doi: 10.1586/erm.12.18.

PMID:
    22468816
    [PubMed - indexed for MEDLINE]
Related citations


Systematic mutagenesis of the murine gammaherpesvirus 68 M2 protein identifies domains important for chronic infection.
Herskowitz JH, Siegel AM, Jacoby MA, Speck SH
J Virol. 2008 Apr; 82(7)3295-310. doi: 10.1128/JVI.02234-07.

PMID:
    18234799
    [PubMed - indexed for MEDLINE]
Related citations


Murine gammaherpesvirus 68 infection is associated with lymphoproliferative disease and lymphoma in BALB beta2 microglobulin-deficient mice.
Tarakanova VL, Suarez F, Tibbetts SA, Jacoby MA, Weck KE, Hess JL, Speck SH, Virgin HW 4th
J Virol. 2005 Dec; 79(23)14668-79.

PMID:
    16282467
    [PubMed - indexed for MEDLINE]
Related citations