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Matthew Goldsmith, MD

Assistant Professor, Pediatrics
Division of Pediatric Critical Care Medicine

Specialty Areas

Pediatric Critical Care Medicine

Board Certifications

Pediatrics
Pediatric Critical Care

Hospital Affiliations

St. Louis Children's Hospital

Areas of Clinical Interest

Post-operative cardiac care, cardiac intensive care, cardiac arrest in children, post-operative care of the Norwood procedure, heart failure in children, shock in children

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: Suite 5S20
Office Phone: 314-454-4488

Education

Education

Fellowship: Pediatric Critical Care Medicine, Washington University School of Medicine, St. Louis, Missouri 2002
Chief Residency: Pediatrics, St. Louis Children's Hospital at Washington University School of Medicine, St. Louis, Missouri 1999
Residency: Pediatrics, St. Louis Children's Hospital at Washington University School of Medicine, St. Louis, Missouri 1998
Medical Degree: University of Toronto, Toronto, Canada 1995
M.Sc.: University of Toronto, Toronto, Canada 1990
B.Sc.: University of Toronto, Toronto, Canada 1987

Publication & Research

Publication & Research

US immigration order strikes against biotech.
Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, Bermingham N, Bloch S, Blum RI, Bolno PB, Bonney MW, Booth B, Bradbury DM, Brauer SK, Byers B, Cagnoni PJ, Cali BM, Ciechanover I, Clark C, Clayman MD, Cleland JL, Cobb P, Cooper R, Currie MG, Diekman J, Dobmeier EL, Doerfler D, Donley EL, Dunsire D, During M, Eckstein JW, Elenko E, Exter NA, Fleming JJ, Flesher GJ, Formela JF, Forrester R, Francois C, Franklin H, Freeman MW, Furst H, Gage LP, Galakatos N, Gallagher BM, Geraghty JA, Gill S, Goeddel DV, Goldsmith MA, Gowen M, Goyal V, Graney T, Grayzel D, Greene B, Grint P, Gutierrez-Ramos JC, Haney B, Ha-Ngoc T, Harris T, Hasnain F, Hata YS, Hecht P, Henshaw L, Heyman R, Hoppenot H, Horvitz HR, Hughes TE, Hutton WS, Isaacs ST, Jenkins A, Jonker J, Kaplan J, Karsen P, Keiper J, Kim J, Kindler J, King R, King V, Kjellson N, Koenig S, Koenig G, Kolchinsky P, Laikind P, Langer RB, Lee JJ, Leff JS, Leicher BA, Leschly N, Levin A, Levin M, Levine AJ, Levy A, Liu DR, Lodish HF, Lopatin U, Love TW, Macdonald G, Maderis GJ, Mahadevia A, Mahanthappa NK, Martin JF, Martin A, Martucci WE, McArthur JG, McCann CM, McCarthy SA, McDonough CG, Mendlein J, Miller L, Miralles D, Moch KI, More B, Myers AG, Narachi MA, Nashat A, Nelson W, Newell WJ, Olle B, Osborn JE, Owens JC, Pande A, Papadopoulos S, Parker HS, Parmar KM, Patterson MR, Paul SM, Perez R, Perry M, Pfeffer CG, Powell M, Pruzanski M, Purcell DJ, Rakhit A, Ramamoorthi K, Rastetter W, Rawcliffe AA, Reid LE, Renaud RC, Rhodes JP, Rieflin WJ, Robins C, Rocklage SM, Rosenblatt M, Rosin JG, Rutter WJ, Saha S, Samuels C, Sato VL, Scangos G, Scarlett JA, Schenkein D, Schreiber SL, Schwab A, Sekhri P, Shah R, Shenk T, Siegall CB, Simon NJ, Simonian N, Stein J, Su M, Szela MT, Taglietti M, Tandon N, Termeer H, Thornberry NA, Tolar M, Ulevitch R, Vaishnaw AK, VanLent A, Varsavsky M, Vlasuk GP, Vounatsos M, Waksal SG, Warma N, Watts RJ, Werber Y, Westphal C, Wierenga W, Williams DE, Williams LR, Xanthopoulos KG, Zohar D, Zweifach SS
Nat Biotechnol. 2017 Mar 7; 35(3)204-206. doi: 10.1038/nbt.3824.

PMID:
    28267733
    [PubMed - in process]
Related citations


Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers.
Goldsmith M, Aggarwal N, Ashani Y, Jubran H, Greisen PJ, Ovchinnikov S, Leader H, Baker D, Sussman JL, Goldenzweig A, Fleishman SJ, Tawfik DS
Protein Eng Des Sel. 2017 Apr 1; 30(4)333-345. doi: 10.1093/protein/gzx003.

PMID:
    28159998
    [PubMed - indexed for MEDLINE]
Related citations


Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro.
Goldsmith M, Eckstein S, Ashani Y, Greisen P Jr, Leader H, Sussman JL, Aggarwal N, Ovchinnikov S, Tawfik DS, Baker D, Thiermann H, Worek F
Arch Toxicol. 2016 Nov; 90(11)2711-2724.

PMID:
    26612364
    [PubMed - indexed for MEDLINE]
Related citations


Successful use of plasma exchange for profound hemolysis in a child with loxoscelism.
Said A, Hmiel P, Goldsmith M, Dietzen D, Hartman ME
Pediatrics. 2014 Nov; 134(5)e1464-7. doi: 10.1542/peds.2013-3338.

PMID:
    25349320
    [PubMed - indexed for MEDLINE]
Related citations


Kinesin family member 6 (kif6) is necessary for spine development in zebrafish.
Buchan JG, Gray RS, Gansner JM, Alvarado DM, Burgert L, Gitlin JD, Gurnett CA, Goldsmith MI
Dev Dyn. 2014 Dec; 243(12)1646-57. doi: 10.1002/dvdy.24208.

PMID:
    25283277
    [PubMed - indexed for MEDLINE]
Related citations


Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis.
Khare SD, Kipnis Y, Greisen P Jr, Takeuchi R, Ashani Y, Goldsmith M, Song Y, Gallaher JL, Silman I, Leader H, Sussman JL, Stoddard BL, Tawfik DS, Baker D
Nat Chem Biol. 2012 Feb 5; 8(3)294-300. doi: 10.1038/nchembio.777.

PMID:
    22306579
    [PubMed - indexed for MEDLINE]
Related citations


A chemical screen to identify novel inhibitors of fin regeneration in zebrafish.
Oppedal D, Goldsmith MI
Zebrafish. 2010 Mar; 7(1)53-60. doi: 10.1089/zeb.2009.0633.

PMID:
    20384483
    [PubMed - indexed for MEDLINE]
Related citations


Severe ceftriaxone-induced hemolysis complicated by diffuse cerebral ischemia in a child with sickle cell disease.
Schuettpelz LG, Behrens D, Goldsmith MI, Druley TE
J Pediatr Hematol Oncol. 2009 Nov; 31(11)870-2. doi: 10.1097/MPH.0b013e3181b7eda2.

PMID:
    19829151
    [PubMed - indexed for MEDLINE]
Related citations


A gain of function mutation causing skeletal overgrowth in the rapunzel mutant.
Green J, Taylor JJ, Hindes A, Johnson SL, Goldsmith MI
Dev Biol. 2009 Oct 1; 334(1)224-34. doi: 10.1016/j.ydbio.2009.07.025.

PMID:
    19632218
    [PubMed - indexed for MEDLINE]
Related citations


A developmental transition in growth control during zebrafish caudal fin development.
Goldsmith MI, Iovine MK, O'Reilly-Pol T, Johnson SL
Dev Biol. 2006 Aug 15; 296(2)450-7.

PMID:
    16844108
    [PubMed - indexed for MEDLINE]
Related citations


Saltatory control of isometric growth in the zebrafish caudal fin is disrupted in long fin and rapunzel mutants.
Goldsmith MI, Fisher S, Waterman R, Johnson SL
Dev Biol. 2003 Jul 15; 259(2)303-17.

PMID:
    12871703
    [PubMed - indexed for MEDLINE]
Related citations


Clinical evaluation of low back pain.
Goldsmith ME, Wiesel SW
Compr Ther. 1998 Aug; 24(8)370-7.

PMID:
    9740982
    [PubMed - indexed for MEDLINE]
Related citations


Spinal Stenosis A Straightforward Approach to a complex Problem.
Goldsmith ME, Wiesel SW
J Clin Rheumatol. 1998 Apr; 4(2)92-5.

PMID:
    19078258
    [PubMed]
Related citations


Redundant and selective roles for erythropoietin receptor tyrosines in erythropoiesis in vivo.
Longmore GD, You Y, Molden J, Liu KD, Mikami A, Lai SY, Pharr P, Goldsmith MA
Blood. 1998 Feb 1; 91(3)870-8.

PMID:
    9446647
    [PubMed - indexed for MEDLINE]
Related citations


Nobel prizes emphasize clinical applications.
Randall T, Goldsmith MF
JAMA. 1990 Nov 7; 264(17)2187.

PMID:
    2214089
    [PubMed - indexed for MEDLINE]
Related citations


Some Problems Involved in the Use of Quaternary Ammonium Compounds as Fabric Disinfectants.
McNeil E, Greenstein M, Stuart LS, Goldsmith MT
Appl Microbiol. 1960 May; 8(3)156-9.

PMID:
    16349591
    [PubMed]
Related citations

Areas of Research Interest

Endothelium and growth control