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Faculty Physicians

Matthew D. Smyth, MD

Professor, Neurosurgery
Professor, Pediatrics
Division of Pediatric Neurosurgery
Director, Pediatric Epilepsy Surgery Program
Director, Pediatric Radiosurgery Program

Specialty Areas

Pediatric Neurosurgery
Pediatric Epilepsy
Craniosynostosis

Board Certifications

American Board of Pediatric Neurological Surgery
American Board of Neurological Surgery

Hospital Affiliations

Shriners Hospital for Children - St. Louis
Barnes-Jewish West County Hospital
St. John's Mercy Hospital - Consulting Staff
St. Louis Children's Hospital
Barnes-Jewish Hospital

Areas of Clinical Interest

Pediatric neurosurgery, epilepsy, craniosynostosis, craniofacial surgery, brain tumors, neuro-endoscopy, chiari malformation, spina bifida, hydrocephalus, syringomyelia, spasticity, neurofibromatosis, tuberous sclerosis, cortical dysplasia.



More information on St. Louis Children's Hospital and craniosynostosis

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: E
Floor: 4
Office Phone: (314) 454-4454
Fax: (314) 454-2818

Education

Education

Fellowship: Pediatric Neurosurgery, Children's Hospital of Alabama at Birmingham, UAB, Birmingham, Alabama 2003
Chief Resident: Neurosurgery, University of California, San Francisco School of Medicine, San Francisco, California 2002
Residency: Neurological Surgery, University of California, San Francisco School of Medicine, San Francisco, California 2002
Residency: Neurological Surgery, University of California, Irvine School of Medicine, Irvine, California 1997
Medical Degree: UC San Francisco School of Medicine, San Francisco, California 1996
B.A.: Neurobiology and Behavior, Cornell University, Ithaca, New York 1992

Publication & Research

Publication & Research

Neosuture formation after endoscope-assisted craniosynostosis repair.
Salehi A, Ott K, Skolnick GB, Nguyen DC, Naidoo SD, Kane AA, Woo AS, Patel KB, Smyth MD
J Neurosurg Pediatr. 2016 Apr 29; 1-5.

PMID:
    27128960
    [PubMed - as supplied by publisher]
Related citations


Chiari malformation Type I surgery in pediatric patients. Part 1: validation of an ICD-9-CM code search algorithm.
Ladner TR, Greenberg JK, Guerrero N, Olsen MA, Shannon CN, Yarbrough CK, Piccirillo JF, Anderson RC, Feldstein NA, Wellons JC 3rd, Smyth MD, Park TS, Limbrick DD Jr
J Neurosurg Pediatr. 2016 May; 17(5)519-24. doi: 10.3171/2015.10.PEDS15370.

PMID:
    26799412
    [PubMed - in process]
Related citations


Chiari malformation Type I surgery in pediatric patients. Part 2: complications and the influence of comorbid disease in California, Florida, and New York.
Greenberg JK, Olsen MA, Yarbrough CK, Ladner TR, Shannon CN, Piccirillo JF, Anderson RC, Wellons JC 3rd, Smyth MD, Park TS, Limbrick DD Jr
J Neurosurg Pediatr. 2016 May; 17(5)525-32. doi: 10.3171/2015.10.PEDS15369.

PMID:
    26799408
    [PubMed - in process]
Related citations


Characterization of complications associated with open and endoscopic craniosynostosis surgery at a single institution.
Han RH, Nguyen DC, Bruck BS, Skolnick GB, Yarbrough CK, Naidoo SD, Patel KB, Kane AA, Woo AS, Smyth MD
J Neurosurg Pediatr. 2016 Mar; 17(3)361-70. doi: 10.3171/2015.7.PEDS15187.

PMID:
    26588461
    [PubMed - in process]
Related citations


In Reply: Chiari Severity Index: A Novel Grading System Intended for Preoperative Counseling.
Greenberg JK, Yarbrough CK, Radmanesh A, Godzik J, Yu M, Jeffe DB, Smyth MD, Park TS, Piccirillo JF, Limbrick DD Jr
Neurosurgery. 2015 Nov; 77(5)E842. doi: 10.1227/NEU.0000000000000936.

PMID:
    26258944
    [PubMed - indexed for MEDLINE]
Related citations


Cranial Base and Posterior Cranial Vault Asymmetry After Open and Endoscopic Repair of Isolated Lambdoid Craniosynostosis.
Zubovic E, Woo AS, Skolnick GB, Naidoo SD, Smyth MD, Patel KB
J Craniofac Surg. 2015 Jul; 26(5)1568-73. doi: 10.1097/SCS.0000000000001891.

PMID:
    26114505
    [PubMed - indexed for MEDLINE]
Related citations


Comparison of Traditional versus Normative Cephalic Index in Patients with Sagittal Synostosis: Measure of Scaphocephaly and Postoperative Outcome.
Dvoracek LA, Skolnick GB, Nguyen DC, Naidoo SD, Smyth MD, Woo AS, Patel KB
Plast Reconstr Surg. 2015 Sep; 136(3)541-8. doi: 10.1097/PRS.0000000000001505.

PMID:
    25989301
    [PubMed - indexed for MEDLINE]
Related citations


Comparison of spinal deformity in children with Chiari I malformation with and without syringomyelia: matched cohort study.
Godzik J, Dardas A, Kelly MP, Holekamp TF, Lenke LG, Smyth MD, Park TS, Leonard JR, Limbrick DD
Eur Spine J. 2016 Feb; 25(2)619-26. doi: 10.1007/s00586-015-4011-1.

PMID:
    25981206
    [PubMed - in process]
Related citations


Subependymal giant cell astrocytoma in the absence of tuberous sclerosis complex: case report.
Beaumont TL, Godzik J, Dahiya S, Smyth MD
J Neurosurg Pediatr. 2015 Aug; 16(2)134-7. doi: 10.3171/2015.1.PEDS13146.

PMID:
    25978531
    [PubMed - indexed for MEDLINE]
Related citations


Validation of an International Classification of Diseases, Ninth Revision Code Algorithm for Identifying Chiari Malformation Type 1 Surgery in Adults.
Greenberg JK, Ladner TR, Olsen MA, Shannon CN, Liu J, Yarbrough CK, Piccirillo JF, Wellons JC 3rd, Smyth MD, Park TS, Limbrick DD
Neurosurgery. 2015 Aug; 77(2)269-73. doi: 10.1227/NEU.0000000000000778.

PMID:
    25924208
    [PubMed - indexed for MEDLINE]
Related citations


Complications and Resource Use Associated With Surgery for Chiari Malformation Type 1 in Adults: A Population Perspective.
Greenberg JK, Ladner TR, Olsen MA, Shannon CN, Liu J, Yarbrough CK, Piccirillo JF, Wellons JC 3rd, Smyth MD, Park TS, Limbrick DD
Neurosurgery. 2015 Aug; 77(2)261-8. doi: 10.1227/NEU.0000000000000777.

PMID:
    25910086
    [PubMed - indexed for MEDLINE]
Related citations


Temperatures achieved in human and canine neocortex during intraoperative passive or active focal cooling.
Smyth MD, Han RH, Yarbrough CK, Patterson EE, Yang XF, Miller JW, Rothman SM, D'Ambrosio R
Ther Hypothermia Temp Manag. 2015 Jun; 5(2)95-103. doi: 10.1089/ther.2014.0025.

PMID:
    25902001
    [PubMed - indexed for MEDLINE]
Related citations


The Effects of Whole-Vault Cranioplasty versus Strip Craniectomy on Long-Term Neuropsychological Outcomes in Sagittal Craniosynostosis.
Derderian CA, Heppner C, Cradock MM, Woo AS, Patel KB, Smyth MD, Viera P, Weprin BE, Seaward J, Smartt JM, Kane AA
Plast Reconstr Surg. 2015 Jul; 136(1)114e-115e. doi: 10.1097/PRS.0000000000001344.

PMID:
    25811700
    [PubMed - indexed for MEDLINE]
Related citations


Osteoblast differentiation profiles define sex specific gene expression patterns in craniosynostosis.
Park SS, Beyer RP, Smyth MD, Clarke CM, Timms AE, Bammler TK, Stamper BD, Mecham BH, Gustafson JA, Cunningham ML
Bone. 2015 Jul; 76169-76. doi: 10.1016/j.bone.2015.03.001.

PMID:
    25753363
    [PubMed - indexed for MEDLINE]
Related citations


The Chiari Severity Index: a preoperative grading system for Chiari malformation type 1.
Greenberg JK, Yarbrough CK, Radmanesh A, Godzik J, Yu M, Jeffe DB, Smyth MD, Park TS, Piccirillo JF, Limbrick DD
Neurosurgery. 2015 Mar; 76(3)279-85; discussion 285. doi: 10.1227/NEU.0000000000000608.

PMID:
    25584956
    [PubMed - indexed for MEDLINE]
Related citations


Effects of open and endoscopic surgery on skull growth and calvarial vault volumes in sagittal synostosis.
Ghenbot RG, Patel KB, Skolnick GB, Naidoo SD, Smyth MD, Woo AS
J Craniofac Surg. 2015 Jan; 26(1)161-4. doi: 10.1097/SCS.0000000000001236.

PMID:
    25569396
    [PubMed - indexed for MEDLINE]
Related citations


Tonsillar pulsatility before and after surgical decompression for children with Chiari malformation type 1: an application for true fast imaging with steady state precession.
Radmanesh A, Greenberg JK, Chatterjee A, Smyth MD, Limbrick DD Jr, Sharma A
Neuroradiology. 2015 Apr; 57(4)387-93. doi: 10.1007/s00234-014-1481-5.

PMID:
    25563631
    [PubMed - indexed for MEDLINE]
Related citations


Are endoscopic and open treatments of metopic synostosis equivalent in treating trigonocephaly and hypotelorism?
Nguyen DC, Patel KB, Skolnick GB, Naidoo SD, Huang AH, Smyth MD, Woo AS
J Craniofac Surg. 2015 Jan; 26(1)129-34. doi: 10.1097/SCS.0000000000001321.

PMID:
    25534056
    [PubMed - indexed for MEDLINE]
Related citations


Surgical management of complex multiloculated hydrocephalus in infants and children.
Akbari SH, Holekamp TF, Murphy TM, Mercer D, Leonard JR, Smyth MD, Park TS, Limbrick DD Jr
Childs Nerv Syst. 2015 Feb; 31(2)243-9. doi: 10.1007/s00381-014-2596-z.

PMID:
    25432856
    [PubMed - indexed for MEDLINE]
Related citations


Outcome methods used in clinical studies of Chiari malformation Type I: a systematic review.
Greenberg JK, Milner E, Yarbrough CK, Lipsey K, Piccirillo JF, Smyth MD, Park TS, Limbrick DD Jr
J Neurosurg. 2015 Feb; 122(2)262-72. doi: 10.3171/2014.9.JNS14406.

PMID:
    25380104
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Cortical dysplasia, animal models of epilepsy, cortical cooling for epilepsy, deep brain stimulation for epilepsy, genetic correlates of craniosynostosis