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Matthew D. Smyth, MD

Professor, Neurosurgery
Professor, Pediatrics
Division of Pediatric Neurosurgery
Director, Pediatric Epilepsy Surgery Program
Director, Pediatric Radiosurgery Program

Specialty Areas

Pediatric Neurosurgery
Pediatric Epilepsy
Craniosynostosis
Gamma Knife

Board Certifications

American Board of Pediatric Neurological Surgery
American Board of Neurological Surgery

Hospital Affiliations

Shriners Hospital for Children - St. Louis
Barnes-Jewish West County Hospital
St. John's Mercy Hospital - Consulting Staff
St. Louis Children's Hospital
Barnes-Jewish Hospital

Areas of Clinical Interest

Pediatric neurosurgery, epilepsy, craniosynostosis, craniofacial surgery, brain tumors, neuro-endoscopy, chiari malformation, spina bifida, hydrocephalus, syringomyelia, spasticity, neurofibromatosis, tuberous sclerosis, cortical dysplasia.



More information on St. Louis Children's Hospital and craniosynostosis

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: E
Floor: 4
Office Phone: (314) 454-4454
Fax: (314) 454-2818

Education

Education

Fellowship: Pediatric Neurosurgery, Children's Hospital of Alabama at Birmingham, UAB, Birmingham, Alabama 2003
Chief Resident: Neurosurgery, University of California, San Francisco School of Medicine, San Francisco, California 2002
Residency: Neurological Surgery, University of California, San Francisco School of Medicine, San Francisco, California 2002
Residency: Neurological Surgery, University of California, Irvine School of Medicine, Irvine, California 1997
Medical Degree: UC San Francisco School of Medicine, San Francisco, California 1996
B.A.: Neurobiology and Behavior, Cornell University, Ithaca, New York 1992

Publication & Research

Publication & Research

Electrophysiological Sequelae of Hemispherotomy in Ipsilateral Human Cortex.
Hawasli AH, Chacko R, Szrama NP, Bundy DT, Pahwa M, Yarbrough CK, Dlouhy BJ, Limbrick DD, Barbour DL, Smyth MD, Leuthardt EC
Front Hum Neurosci. 2017; 11149. doi: 10.3389/fnhum.2017.00149.

PMID:
    28424599
    [PubMed - in process]
Related citations


Corpus callosotomy-Open and endoscopic surgical techniques.
Smyth MD, Vellimana AK, Asano E, Sood S
Epilepsia. 2017 Apr; 58 Suppl 173-79. doi: 10.1111/epi.13681.

PMID:
    28386923
    [PubMed - in process]
Related citations


The use of hippocampal volumetric measurements to improve diagnostic accuracy in pediatric patients with mesial temporal sclerosis.
Guzmán Pérez-Carrillo GJ, Owen C, Schwetye KE, McFarlane S, Vellimana AK, Mar S, Miller-Thomas MM, Shimony JS, Smyth MD, Benzinger TL
J Neurosurg Pediatr. 2017 Mar 24; 1-9. doi: 10.3171/2016.12.PEDS16335.

PMID:
    28338446
    [PubMed - as supplied by publisher]
Related citations


Anthropometric Outcome Measures in Patients With Metopic Craniosynostosis.
Farber SJ, Nguyen DC, Skolnick GB, Naidoo SD, Smyth MD, Patel KB
J Craniofac Surg. 2017 Feb 15; doi: 10.1097/SCS.0000000000003495.

PMID:
    28207460
    [PubMed - as supplied by publisher]
Related citations


Hemispherotomy in children with electrical status epilepticus of sleep.
Jeong A, Strahle J, Vellimana AK, Limbrick DD Jr, Smyth MD, Bertrand M
J Neurosurg Pediatr. 2017 Jan; 19(1)56-62. doi: 10.3171/2016.8.PEDS16319.

PMID:
    27791702
    [PubMed - indexed for MEDLINE]
Related citations


Utilizing personalized stereotactic frames for laser interstitial thermal ablation of posterior fossa and mesiotemporal brain lesions: a single-institution series.
Dadey DY, Kamath AA, Smyth MD, Chicoine MR, Leuthardt EC, Kim AH
Neurosurg Focus. 2016 Oct; 41(4)E4.

PMID:
    27690652
    [PubMed - indexed for MEDLINE]
Related citations


Laser interstitial thermal therapy for subependymal giant cell astrocytoma: technical case report.
Dadey DY, Kamath AA, Leuthardt EC, Smyth MD
Neurosurg Focus. 2016 Oct; 41(4)E9.

PMID:
    27690646
    [PubMed - indexed for MEDLINE]
Related citations


Endoscope-assisted management of sagittal synostosis: wide vertex suturectomy and barrel stave osteotomies versus narrow vertex suturectomy.
Dlouhy BJ, Nguyen DC, Patel KB, Hoben GM, Skolnick GB, Naidoo SD, Woo AS, Smyth MD
J Neurosurg Pediatr. 2016 Dec; 25(6)674-678.

PMID:
    27611899
    [PubMed - indexed for MEDLINE]
Related citations


Comparison of the accuracy and proximal shunt failure rate of freehand placement versus intraoperative guidance in parietooccipital ventricular catheter placement.
Wilson TJ, McCoy KE, Al-Holou WN, Molina SL, Smyth MD, Sullivan SE
Neurosurg Focus. 2016 Sep; 41(3)E10. doi: 10.3171/2016.5.FOCUS16159.

PMID:
    27581306
    [PubMed - indexed for MEDLINE]
Related citations


Palliative epilepsy surgery in Dravet syndrome-case series and review of the literature.
Dlouhy BJ, Miller B, Jeong A, Bertrand ME, Limbrick DD Jr, Smyth MD
Childs Nerv Syst. 2016 Sep; 32(9)1703-8. doi: 10.1007/s00381-016-3201-4.

PMID:
    27465677
    [PubMed - in process]
Related citations


Rasmussen encephalitis tissue transfer program.
Kruse CA, Pardo CA, Hartman AL, Jallo G, Vining EP, Voros J, Gaillard WD, Liu J, Oluigbo C, Malone S, Bleasel AF, Dexter M, Micati A, Velasco TR, Machado HR, Martino AM, Huang A, Wheatley BM, Grant GA, Granata T, Freri E, Garbelli R, Koh S, Nordli DR, Campos AR, O'Neill B, Handler MH, Chapman KE, Wilfong AA, Curry DJ, Yaun A, Madsen JR, Smyth MD, Mercer D, Bingaman W, Harvey AS, Leventer RJ, Lockhart PJ, Gillies G, Pope K, Giller CA, Park YD, Rojiani AM, Sharma SJ, Jenkins P, Tung S, Huynh MN, Chirwa TW, Cepeda C, Levine MS, Chang JW, Owens GC, Vinters HV, Mathern GW
Epilepsia. 2016 Jun; 57(6)1005-7. doi: 10.1111/epi.13383.

PMID:
    27286752
    [PubMed - in process]
Related citations


Neosuture formation after endoscope-assisted craniosynostosis repair.
Salehi A, Ott K, Skolnick GB, Nguyen DC, Naidoo SD, Kane AA, Woo AS, Patel KB, Smyth MD
J Neurosurg Pediatr. 2016 Aug; 18(2)196-200. doi: 10.3171/2016.2.PEDS15231.

PMID:
    27128960
    [PubMed - indexed for MEDLINE]
Related citations


Chiari malformation Type I surgery in pediatric patients. Part 1: validation of an ICD-9-CM code search algorithm.
Ladner TR, Greenberg JK, Guerrero N, Olsen MA, Shannon CN, Yarbrough CK, Piccirillo JF, Anderson RC, Feldstein NA, Wellons JC 3rd, Smyth MD, Park TS, Limbrick DD Jr
J Neurosurg Pediatr. 2016 May; 17(5)519-24. doi: 10.3171/2015.10.PEDS15370.

PMID:
    26799412
    [PubMed - indexed for MEDLINE]
Related citations


Chiari malformation Type I surgery in pediatric patients. Part 2: complications and the influence of comorbid disease in California, Florida, and New York.
Greenberg JK, Olsen MA, Yarbrough CK, Ladner TR, Shannon CN, Piccirillo JF, Anderson RC, Wellons JC 3rd, Smyth MD, Park TS, Limbrick DD Jr
J Neurosurg Pediatr. 2016 May; 17(5)525-32. doi: 10.3171/2015.10.PEDS15369.

PMID:
    26799408
    [PubMed - indexed for MEDLINE]
Related citations


Characterization of complications associated with open and endoscopic craniosynostosis surgery at a single institution.
Han RH, Nguyen DC, Bruck BS, Skolnick GB, Yarbrough CK, Naidoo SD, Patel KB, Kane AA, Woo AS, Smyth MD
J Neurosurg Pediatr. 2016 Mar; 17(3)361-70. doi: 10.3171/2015.7.PEDS15187.

PMID:
    26588461
    [PubMed - indexed for MEDLINE]
Related citations


In Reply: Chiari Severity Index: A Novel Grading System Intended for Preoperative Counseling.
Greenberg JK, Yarbrough CK, Radmanesh A, Godzik J, Yu M, Jeffe DB, Smyth MD, Park TS, Piccirillo JF, Limbrick DD Jr
Neurosurgery. 2015 Nov; 77(5)E842. doi: 10.1227/NEU.0000000000000936.

PMID:
    26258944
    [PubMed - indexed for MEDLINE]
Related citations


Cranial Base and Posterior Cranial Vault Asymmetry After Open and Endoscopic Repair of Isolated Lambdoid Craniosynostosis.
Zubovic E, Woo AS, Skolnick GB, Naidoo SD, Smyth MD, Patel KB
J Craniofac Surg. 2015 Jul; 26(5)1568-73. doi: 10.1097/SCS.0000000000001891.

PMID:
    26114505
    [PubMed - indexed for MEDLINE]
Related citations


Comparison of Traditional versus Normative Cephalic Index in Patients with Sagittal Synostosis: Measure of Scaphocephaly and Postoperative Outcome.
Dvoracek LA, Skolnick GB, Nguyen DC, Naidoo SD, Smyth MD, Woo AS, Patel KB
Plast Reconstr Surg. 2015 Sep; 136(3)541-8. doi: 10.1097/PRS.0000000000001505.

PMID:
    25989301
    [PubMed - indexed for MEDLINE]
Related citations


Comparison of spinal deformity in children with Chiari I malformation with and without syringomyelia: matched cohort study.
Godzik J, Dardas A, Kelly MP, Holekamp TF, Lenke LG, Smyth MD, Park TS, Leonard JR, Limbrick DD
Eur Spine J. 2016 Feb; 25(2)619-26. doi: 10.1007/s00586-015-4011-1.

PMID:
    25981206
    [PubMed - indexed for MEDLINE]
Related citations


Subependymal giant cell astrocytoma in the absence of tuberous sclerosis complex: case report.
Beaumont TL, Godzik J, Dahiya S, Smyth MD
J Neurosurg Pediatr. 2015 Aug; 16(2)134-7. doi: 10.3171/2015.1.PEDS13146.

PMID:
    25978531
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Cortical dysplasia, animal models of epilepsy, cortical cooling for epilepsy, deep brain stimulation for epilepsy, genetic correlates of craniosynostosis