Patient Portal

Matthew B. Spraker, MD, PhD

Assistant Professor, Radiation Oncology

Specialty Areas

Radiation Oncology

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Physician Referral Required

Areas of Clinical Interest

Soft tissue sarcoma, palliative radiotherapy, stereotactic radiation therapy

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

Barnes-Jewish Hospital

1 Barnes-Jewish Hospital Plaza
St. Louis, MO 63110

Center for Advanced Medicine - South County

5201 Midamerica Plaza
St. Louis, MO 63129

Center for Advanced Medicine
Siteman Cancer Center

4921 Parkview Place
St. Louis, MO 63110

Education

Education

Residency - Radiation oncology: University of Washington - Seattle, Washington 2018
Internship - Internal medicine: University of Illinois Hospital and Health Science System - Chicago, IL 2014
MD: University of Chicago - Chicago, IL 2013
PhD - Bioengineering - Biomedical imaging: University of Illinois at Chicago - Chicago, IL 2009
BS - Biology/chemistry: Indiana University in Bloomington -- Bloomington, IN 2005

Publication & Research

Publication & Research

MRI Radiomic Features Are Independently Associated With Overall Survival in Soft Tissue Sarcoma.
Spraker MB, Wootton LS, Hippe DS, Ball KC, Peeken JC, Macomber MW, Chapman TR, Hoff MN, Kim EY, Pollack SM, Combs SE, Nyflot MJ
Adv Radiat Oncol. 2019 Apr-Jun; 4(2)413-421. doi: 10.1016/j.adro.2019.02.003.

PMID:
    31011687
    [PubMed]
Related citations


CT-based radiomic features predict tumor grading and have prognostic value in patients with soft tissue sarcomas treated with neoadjuvant radiation therapy.
Peeken JC, Bernhofer M, Spraker MB, Pfeiffer D, Devecka M, Thamer A, Shouman MA, Ott A, Nüsslin F, Mayr NA, Rost B, Nyflot MJ, Combs SE
Radiother Oncol. 2019 Jun; 135187-196. doi: 10.1016/j.radonc.2019.01.004.

PMID:
    30961895
    [PubMed - in process]
Related citations


Clinical Outcomes and Prognostic Features of Angiosarcoma: Significance of Prior Radiation Therapy.
Merfeld E, Gabani P, Spraker MB, Zoberi I, Kim H, Van Tine B, Chrisinger J, Michalski JM
Clin Oncol (R Coll Radiol). 2019 Apr; 31(4)232-241. doi: 10.1016/j.clon.2019.01.006.

PMID:
    30718086
    [PubMed - in process]
Related citations


Analysis of Gastrointestinal Toxicity in Patients Receiving Proton Beam Therapy for Prostate Cancer: A Single-Institution Experience.
Lee HJ Jr, Macomber MW, Spraker MB, Bowen SR, Hippe D, Fung A, Russell KJ, Laramore GE, Rengan R, Liao J, Apisarnthanarax S, Zeng J
Adv Radiat Oncol. 2019 Jan-Mar; 4(1)70-78. doi: 10.1016/j.adro.2018.08.002.

PMID:
    30706013
    [PubMed]
Related citations


Radiation oncology resident training in patient safety and quality improvement: a national survey of residency program directors.
Spraker MB, Nyflot MJ, Hendrickson KRG, Terezakis S, Fogh SE, Kane GM, Ford EC, Zeng J
Radiat Oncol. 2018 Sep 24; 13(1)186. doi: 10.1186/s13014-018-1128-5.

PMID:
    30249302
    [PubMed - indexed for MEDLINE]
Related citations


Early toxicity and patient reported quality-of-life in patients receiving proton therapy for localized prostate cancer: a single institutional review of prospectively recorded outcomes.
Lee HJ Jr, Macomber MW, Spraker MB, Bowen SR, Hippe DS, Fung A, Russell KJ, Laramore GE, Rengan R, Liao J, Apisarnthanarax S, Zeng J
Radiat Oncol. 2018 Sep 17; 13(1)179. doi: 10.1186/s13014-018-1127-6.

PMID:
    30223877
    [PubMed - indexed for MEDLINE]
Related citations


Emerging Targeted and Immune-Based Therapies in Sarcoma.
Pollack SM, Ingham M, Spraker MB, Schwartz GK
J Clin Oncol. 2018 Jan 10; 36(2)125-135. doi: 10.1200/JCO.2017.75.1610.

PMID:
    29220291
    [PubMed - indexed for MEDLINE]
Related citations


A patient safety education program in a medical physics residency.
Ford EC, Nyflot M, Spraker MB, Kane G, Hendrickson KRG
J Appl Clin Med Phys. 2017 Nov; 18(6)268-274. doi: 10.1002/acm2.12166.

PMID:
    28895282
    [PubMed - indexed for MEDLINE]
Related citations


Evaluation of near-miss and adverse events in radiation oncology using a comprehensive causal factor taxonomy.
Spraker MB, Fain R 3rd, Gopan O, Zeng J, Nyflot M, Jordan L, Kane G, Ford E
Pract Radiat Oncol. 2017 Sep - Oct; 7(5)346-353. doi: 10.1016/j.prro.2017.05.008.

PMID:
    28865683
    [PubMed - indexed for MEDLINE]
Related citations


Solitary Orbital Metastasis 35 Years after a Diagnosis of Lobular Carcinoma in Situ.
Spraker MB, Francis CE, Korde L, Kim J, Halasz L
Cureus. 2017 Jun 28; 9(6)e1404. doi: 10.7759/cureus.1404.

PMID:
    28852601
    [PubMed]
Related citations


T-cell infiltration and clonality correlate with programmed cell death protein 1 and programmed death-ligand 1 expression in patients with soft tissue sarcomas.
Pollack SM, He Q, Yearley JH, Emerson R, Vignali M, Zhang Y, Redman MW, Baker KK, Cooper S, Donahue B, Loggers ET, Cranmer LD, Spraker MB, Seo YD, Pillarisetty VG, Ricciotti RW, Hoch BL, McClanahan TK, Murphy E, Blumenschein WM, Townson SM, Benzeno S, Riddell SR, Jones RL
Cancer. 2017 Sep 1; 123(17)3291-3304. doi: 10.1002/cncr.30726.

PMID:
    28463396
    [PubMed - indexed for MEDLINE]
Related citations


A survey of residents' experience with patient safety and quality improvement concepts in radiation oncology.
Spraker MB, Nyflot M, Hendrickson K, Ford E, Kane G, Zeng J
Pract Radiat Oncol. 2017 Jul - Aug; 7(4)e253-e259. doi: 10.1016/j.prro.2016.11.008.

PMID:
    28462894
    [PubMed - indexed for MEDLINE]
Related citations


An analysis of patient characteristics and clinical outcomes in primary pulmonary sarcoma.
Spraker MB, Bair E, Bair R, Connell PP, Mahmood U, Koshy M
J Thorac Oncol. 2013 Feb; 8(2)147-51. doi: 10.1097/JTO.0b013e318277401f.

PMID:
    23263688
    [PubMed - indexed for MEDLINE]
Related citations


Specific cerebellar regions are related to force amplitude and rate of force development.
Spraker MB, Corcos DM, Kurani AS, Prodoehl J, Swinnen SP, Vaillancourt DE
Neuroimage. 2012 Jan 16; 59(2)1647-56. doi: 10.1016/j.neuroimage.2011.09.019.

PMID:
    21963915
    [PubMed - indexed for MEDLINE]
Related citations


Effects of aging on the ventral and dorsal substantia nigra using diffusion tensor imaging.
Vaillancourt DE, Spraker MB, Prodoehl J, Zhou XJ, Little DM
Neurobiol Aging. 2012 Jan; 33(1)35-42. doi: 10.1016/j.neurobiolaging.2010.02.006.

PMID:
    20359780
    [PubMed - indexed for MEDLINE]
Related citations


Basal ganglia hypoactivity during grip force in drug naïve Parkinson's disease.
Spraker MB, Prodoehl J, Corcos DM, Comella CL, Vaillancourt DE
Hum Brain Mapp. 2010 Dec; 31(12)1928-41. doi: 10.1002/hbm.20987.

PMID:
    20225221
    [PubMed - indexed for MEDLINE]
Related citations


Cortical and subcortical mechanisms for precisely controlled force generation and force relaxation.
Spraker MB, Corcos DM, Vaillancourt DE
Cereb Cortex. 2009 Nov; 19(11)2640-50. doi: 10.1093/cercor/bhp015.

PMID:
    19254959
    [PubMed - indexed for MEDLINE]
Related citations


High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease.
Vaillancourt DE, Spraker MB, Prodoehl J, Abraham I, Corcos DM, Zhou XJ, Comella CL, Little DM
Neurology. 2009 Apr 21; 72(16)1378-84. doi: 10.1212/01.wnl.0000340982.01727.6e.

PMID:
    19129507
    [PubMed - indexed for MEDLINE]
Related citations


Role of individual basal ganglia nuclei in force amplitude generation.
Spraker MB, Yu H, Corcos DM, Vaillancourt DE
J Neurophysiol. 2007 Aug; 98(2)821-34.

PMID:
    17567775
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Interdiscplinary care, clinical informatics, quantitative imaging