Patient Portal

Matthew A. Ciorba, MD

Associate Professor, Medicine
Division of Gastroenterology
Director, Inflammatory Bowel Disease Program

Specialty Areas

Gastroenterology
Gastrointestinal Disease
Inflammatory Bowel Disease

Board Certifications

Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Gastroenterology, inflammatory bowel disease, Crohn's disease

  • Location(s)
  • Education
  • Publication & Research
  • In the News
  • Financial Disclosures
  • Videos

Location(s)

Location(s)

Center for Advanced Medicine

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 8
Office Phone: 314-747-2066

Education

Education

Fellowship: Gastroenterology, Washington University School of Medicine, St. Louis, Missouri 2007
Residency: Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 2003
M.D.: University of Iowa College of Medicine, Iowa City, Iowa 2001
B.S.: Exercise Science, University of Iowa College of Liberal Arts, Iowa City, Iowa 1996

Publication & Research

Publication & Research

Impact of Bariatric Surgery on the Long-term Disease Course of Inflammatory Bowel Disease.
Neto MBB, Gregory MH, Ramos GP, Bazerbachi F, Bruining DH, Abu Dayyeh BK, Kushnir VM, Raffals LE, Ciorba MA, Loftus EV, Deepak P
Inflamm Bowel Dis. 2019 Oct 15; pii: izz236. doi: 10.1093/ibd/izz236.

PMID:
    31613968
    [PubMed - as supplied by publisher]
Related citations


The Association of Medications and Vaccination with Risk of Pneumonia in Inflammatory Bowel Disease.
Gregory MH, Ciorba MA, Wiitala WL, Stidham RW, Higgins P, Morley SC, Hou JK, Feagins LA, Govani SM, Cohen-Mekelburg SA, Waljee AK
Inflamm Bowel Dis. 2019 Aug 27; pii: izz189. doi: 10.1093/ibd/izz189.

PMID:
    31504531
    [PubMed - as supplied by publisher]
Related citations


Hyaluronic acid binding to TLR4 promotes proliferation and blocks apoptosis in colon cancer.
Makkar S, Riehl TE, Chen B, Yan Y, Alvarado DM, Ciorba MA, Stenson WF
Mol Cancer Ther. 2019 Sep 4; pii: molcanther.1225.2018. doi: 10.1158/1535-7163.MCT-18-1225.

PMID:
    31484704
    [PubMed - as supplied by publisher]
Related citations


Epithelial Indoleamine 2,3-Dioxygenase 1 Modulates Aryl Hydrocarbon Receptor and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota.
Alvarado DM, Chen B, Iticovici M, Thaker AI, Dai N, VanDussen KL, Shaikh N, Lim CK, Guillemin GJ, Tarr PI, Ciorba MA
Gastroenterology. 2019 Oct; 157(4)1093-1108.e11. doi: 10.1053/j.gastro.2019.07.013.

PMID:
    31325428
    [PubMed - in process]
Related citations


Enterotoxigenic Escherichia coli-blood group A interactions intensify diarrheal severity.
Kumar P, Kuhlmann FM, Chakraborty S, Bourgeois AL, Foulke-Abel J, Tumala B, Vickers TJ, Sack DA, DeNearing B, Harro CD, Wright WS, Gildersleeve JC, Ciorba MA, Santhanam S, Porter CK, Gutierrez RL, Prouty MG, Riddle MS, Polino A, Sheikh A, Donowitz M, Fleckenstein JM
J Clin Invest. 2019 Jul 1; 129(7)2980. doi: 10.1172/JCI130874.

PMID:
    31259744
    [PubMed]
Related citations


Dynamic immunoglobulin responses to gut bacteria during inflammatory bowel disease.
Rengarajan S, Vivio EE, Parkes M, Peterson DA, Roberson EDO, Newberry RD, Ciorba MA, Hsieh CS
Gut Microbes. 2019 Jun 16; 1-16. doi: 10.1080/19490976.2019.1626683.

PMID:
    31203722
    [PubMed - as supplied by publisher]
Related citations


Crohn's Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping.
McHenry S, Sharma Y, Tirath A, Tsai R, Mintz A, Fraum TJ, Salter A, Browning JD, Flores AG, Davidson NO, Fowler KJ, Ciorba MA, Deepak P
Clin Gastroenterol Hepatol. 2019 Mar 12; pii: S1542-3565(19)30256-3. doi: 10.1016/j.cgh.2019.02.045.

PMID:
    30876963
    [PubMed - as supplied by publisher]
Related citations


Influence of Crohn's disease related polymorphisms in innate immune function on ileal microbiome.
Li E, Zhang Y, Tian X, Wang X, Gathungu G, Wolber A, Shiekh SS, Sartor RB, Davidson NO, Ciorba MA, Zhu W, Nelson LM, Robertson CE, Frank DN
PLoS One. 2019; 14(2)e0213108. doi: 10.1371/journal.pone.0213108.

PMID:
    30818349
    [PubMed - in process]
Related citations


Efficacy of Vedolizumab for Refractory Pouchitis of the Ileo-anal Pouch: Results From a Multicenter US Cohort.
Gregory M, Weaver KN, Hoversten P, Hicks SB, Patel D, Ciorba MA, Gutierrez AM, Beniwal-Patel P, Palam S, Syal G, Herfarth HH, Christophi G, Raffals L, Barnes EL, Deepak P
Inflamm Bowel Dis. 2019 Aug 20; 25(9)1569-1576. doi: 10.1093/ibd/izz030.

PMID:
    30810748
    [PubMed - in process]
Related citations


Successful Treatment of Pyoderma Gangrenosum with Concomitant Tofacitinib and Infliximab.
Gregory MH, Ciorba MA, Deepak P, Christophi GP
Inflamm Bowel Dis. 2019 Jun 18; 25(7)e87-e88. doi: 10.1093/ibd/izz015.

PMID:
    30753456
    [PubMed - in process]
Related citations


IDO1 and Kynurenine Pathway Metabolites Activate PI3K-Akt Signaling in the Neoplastic Colon Epithelium to Promote Cancer Cell Proliferation and Inhibit Apoptosis.
Bishnupuri KS, Alvarado DM, Khouri AN, Shabsovich M, Chen B, Dieckgraefe BK, Ciorba MA
Cancer Res. 2019 Mar 15; 79(6)1138-1150. doi: 10.1158/0008-5472.CAN-18-0668.

PMID:
    30679179
    [PubMed - in process]
Related citations


Insights into How Probiotics Colonize the Healthy Human Gut.
Ferreiro A, Dantas G, Ciorba MA
Gastroenterology. 2019 Feb; 156(3)820-822. doi: 10.1053/j.gastro.2019.01.022.

PMID:
    30659834
    [PubMed]
Related citations


Anti-Tumour Necrosis Factor Therapy for Inflammatory Bowel Diseases Do Not Impact Serious Infections after Arthroplasty.
Gregory MH, McKinnon A, Stwalley D, Hippensteel KJ, Loftus EV Jr, Ciorba MA, Olsen MA, Deepak P
J Crohns Colitis. 2019 Feb 1; 13(2)182-188. doi: 10.1093/ecco-jcc/jjy148.

PMID:
    30256926
    [PubMed - indexed for MEDLINE]
Related citations


<i>Lactobacillus rhamnosus</i> GG protects the intestinal epithelium from radiation injury through release of lipoteichoic acid, macrophage activation and the migration of mesenchymal stem cells.
Riehl TE, Alvarado D, Ee X, Zuckerman A, Foster L, Kapoor V, Thotala D, Ciorba MA, Stenson WF
Gut. 2019 Jun; 68(6)1003-1013. doi: 10.1136/gutjnl-2018-316226.

PMID:
    29934438
    [PubMed - indexed for MEDLINE]
Related citations


Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis.
Sofia MA, Ciorba MA, Meckel K, Lim CK, Guillemin GJ, Weber CR, Bissonnette M, Pekow JR
Inflamm Bowel Dis. 2018 Jun 8; 24(7)1471-1480. doi: 10.1093/ibd/izy103.

PMID:
    29796641
    [PubMed - indexed for MEDLINE]
Related citations


Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn's Disease.
VanDussen KL, Stojmirović A, Li K, Liu TC, Kimes PK, Muegge BD, Simpson KF, Ciorba MA, Perrigoue JG, Friedman JR, Towne JE, Head RD, Stappenbeck TS
Gastroenterology. 2018 Sep; 155(3)815-828. doi: 10.1053/j.gastro.2018.05.028.

PMID:
    29782846
    [PubMed - indexed for MEDLINE]
Related citations


Enterotoxigenic Escherichia coli-blood group A interactions intensify diarrheal severity.
Kumar P, Kuhlmann FM, Chakraborty S, Bourgeois AL, Foulke-Abel J, Tumala B, Vickers TJ, Sack DA, DeNearing B, Harro CD, Wright WS, Gildersleeve JC, Ciorba MA, Santhanam S, Porter CK, Gutierrez RL, Prouty MG, Riddle MS, Polino A, Sheikh A, Donowitz M, Fleckenstein JM
J Clin Invest. 2018 Aug 1; 128(8)3298-3311. doi: 10.1172/JCI97659.

PMID:
    29771685
    [PubMed - indexed for MEDLINE]
Related citations


Prophylactic probiotics for cancer therapy-induced diarrhoea: a meta-analysis.
Wardill HR, Van Sebille YZA, Ciorba MA, Bowen JM
Curr Opin Support Palliat Care. 2018 Jun; 12(2)187-197. doi: 10.1097/SPC.0000000000000338.

PMID:
    29547491
    [PubMed - indexed for MEDLINE]
Related citations


A Role for Salivary Peptides in the Innate Defense Against Enterotoxigenic Escherichia coli.
Brown JW, Badahdah A, Iticovici M, Vickers TJ, Alvarado DM, Helmerhorst EJ, Oppenheim FG, Mills JC, Ciorba MA, Fleckenstein JM, Bullitt E
J Infect Dis. 2018 Apr 11; 217(9)1435-1441. doi: 10.1093/infdis/jiy032.

PMID:
    29528423
    [PubMed - indexed for MEDLINE]
Related citations


Challenges in Using Real-world Clinical Practice Records for Validation of Clinical Trial Data in Inflammatory Bowel Disease: Lessons Learned.
Afzali A, Ciorba MA, Schwartz DA, Sharaf M, Fourment C, Ritter T, Wolf DC, Shafran I, Randall CW, Kane SV
Inflamm Bowel Dis. 2017 Dec 19; 24(1)2-4. doi: 10.1093/ibd/izx015.

PMID:
    29272481
    [PubMed - indexed for MEDLINE]
Related citations

In the News

In the News

Matthew Ciorba, MD

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians and health professionals are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians and health professionals work collaboratively with pharmaceutical, medical device or other medical care related companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our physicians and health professionals have an ownership or potential ownership interest in a commercial company; and/or are paid by a commercial company to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians or health professionals must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this website, physicians and health professionals earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following financial interests during calendar year 2018:

Company Name: Abbott

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $40,000 - $59,999

Reporting Date: May 01, 2019


Company Name: Takeda Pharmaceuticals U.S.A., Inc.

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $60,000 - $79,999

Reporting Date: May 01, 2019

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