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Mark J. Manary, MD

Helene B Roberson Prof of Pediatrics
Director, Global Harvest Alliance,

Specialty Areas

Pediatric Emergency Medicine

Board Certifications

Pediatrics
Pediatric Emergency Medicine

Hospital Affiliations

St. Louis Children's Hospital

Areas of Clinical Interest

Nutrition, developing countries-nutrition, Potassium supplementation, protein kenetics, kwashiorkor

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: First Floor
Office Phone: 314-454-6111

Education

Education

Residency: Pediatrics, St. Louis Children's Hospital, St. Louis, Missouri
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1982
B.S.: Chemistry & Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 1977

Publication & Research

Publication & Research

Trial of ready-to-use supplemental food and corn-soy blend in pregnant Malawian women with moderate malnutrition: a randomized controlled clinical trial.
Callaghan-Gillespie M, Schaffner AA, Garcia P, Fry J, Eckert R, Malek S, Trehan I, Thakwalakwa C, Maleta KM, Manary MJ, Papathakis PC
Am J Clin Nutr. 2017 Aug 9; pii: ajcn157198. doi: 10.3945/ajcn.117.157198.

PMID:
    28793991
    [PubMed - as supplied by publisher]
Related citations


Effect of a package of health and nutrition services on sustained recovery in children after moderate acute malnutrition and factors related to sustaining recovery: a cluster-randomized trial.
Stobaugh HC, Bollinger LB, Adams SE, Crocker AH, Grise JB, Kennedy JA, Thakwalakwa C, Maleta KM, Dietzen DJ, Manary MJ, Trehan I
Am J Clin Nutr. 2017 Aug; 106(2)657-666. doi: 10.3945/ajcn.116.149799.

PMID:
    28615258
    [PubMed - indexed for MEDLINE]
Related citations


Do Vulnerable Populations Consume Adequate Amounts of Dietary Protein?
Manary MJ, Callaghan M
J Nutr. 2017 May; 147(5)725-726. doi: 10.3945/jn.117.248252.

PMID:
    28404831
    [PubMed - in process]
Related citations


Drug-development concepts as guides for optimizing clinical trials of supplemental zinc for populations at risk of deficiency or diarrhea.
Alpers DH, Young GP, Tran CD, Mortimer EK, Gopalsamy GL, Krebs NF, Manary MJ, Ramakrishna BS, Binder HJ, Brown IL, Miller LV
Nutr Rev. 2017 Mar 1; 75(3)147-162. doi: 10.1093/nutrit/nuw065.

PMID:
    28399577
    [PubMed - indexed for MEDLINE]
Related citations


African Children with Severe Pneumonia Remain at High Risk for Death Even After Discharge.
Heikens GT, Manary MJ, Trehan I
Paediatr Perinat Epidemiol. 2017 May; 31(3)243-244. doi: 10.1111/ppe.12350.

PMID:
    28387423
    [PubMed]
Related citations


Statoviruses, A novel taxon of RNA viruses present in the gastrointestinal tracts of diverse mammals.
Janowski AB, Krishnamurthy SR, Lim ES, Zhao G, Brenchley JM, Barouch DH, Thakwalakwa C, Manary MJ, Holtz LR, Wang D
Virology. 2017 Apr; 50436-44. doi: 10.1016/j.virol.2017.01.010.

PMID:
    28152382
    [PubMed - indexed for MEDLINE]
Related citations


Environmental Enteric Dysfunction and the Fecal Microbiota in Malawian Children.
Ordiz MI, Stephenson K, Agapova S, Wylie KM, Maleta K, Martin J, Trehan I, Tarr PI, Manary MJ
Am J Trop Med Hyg. 2017 Feb 8; 96(2)473-476. doi: 10.4269/ajtmh.16-0617.

PMID:
    27956653
    [PubMed - indexed for MEDLINE]
Related citations


Antibiotics as part of the management of severe acute malnutrition.
Trehan I, Goldbach HS, LaGrone LN, Meuli GJ, Wang RJ, Maleta KM, Manary MJ
Malawi Med J. 2016 Sep; 28(3)123-130.

PMID:
    27895846
    [PubMed - indexed for MEDLINE]
Related citations


A Combined Intervention of Zinc, Multiple Micronutrients, and Albendazole Does Not Ameliorate Environmental Enteric Dysfunction or Stunting in Rural Malawian Children in a Double-Blind Randomized Controlled Trial.
Wang AZ, Shulman RJ, Crocker AH, Thakwalakwa C, Maleta KM, Devaraj S, Manary MJ, Trehan I
J Nutr. 2017 Jan; 147(1)97-103. doi: 10.3945/jn.116.237735.

PMID:
    27807040
    [PubMed - indexed for MEDLINE]
Related citations


Metabolomic Changes in Serum of Children with Different Clinical Diagnoses of Malnutrition.
Di Giovanni V, Bourdon C, Wang DX, Seshadri S, Senga E, Versloot CJ, Voskuijl W, Semba RD, Trehan I, Moaddel R, Ordiz MI, Zhang L, Parkinson J, Manary MJ, Bandsma RH
J Nutr. 2016 Dec; 146(12)2436-2444.

PMID:
    27807038
    [PubMed - indexed for MEDLINE]
Related citations


Environmental Enteric Dysfunction Is Associated With Poor Linear Growth and Can Be Identified by Host Fecal mRNAs.
Ordiz MI, Shaikh N, Trehan I, Maleta K, Stauber J, Shulman R, Devaraj S, Tarr PI, Manary MJ
J Pediatr Gastroenterol Nutr. 2016 Nov; 63(5)453-459.

PMID:
    27347722
    [PubMed - in process]
Related citations


Perspective: The Potential Role of Essential Amino Acids and the Mechanistic Target of Rapamycin Complex 1 (mTORC1) Pathway in the Pathogenesis of Child Stunting.
Semba RD, Trehan I, Gonzalez-Freire M, Kraemer K, Moaddel R, Ordiz MI, Ferrucci L, Manary MJ
Adv Nutr. 2016 Sep; 7(5)853-65. doi: 10.3945/an.116.013276.

PMID:
    27633102
    [PubMed - in process]
Related citations


Amoxicillin for Severe Acute Malnutrition in Children.
Trehan I, Schechtman KB, Manary MJ
N Engl J Med. 2016 Jul 14; 375(2)191. doi: 10.1056/NEJMc1605388#SA2.

PMID:
    27410940
    [PubMed - indexed for MEDLINE]
Related citations


Environmental Enteric Dysfunction Is Associated With Altered Bile Acid Metabolism.
Semba RD, Gonzalez-Freire M, Moaddel R, Trehan I, Maleta KM, Khadeer M, Ordiz MI, Ferrucci L, Manary MJ
J Pediatr Gastroenterol Nutr. 2017 Apr; 64(4)536-540. doi: 10.1097/MPG.0000000000001313.

PMID:
    27322559
    [PubMed - in process]
Related citations


Metabolic alterations in children with environmental enteric dysfunction.
Semba RD, Shardell M, Trehan I, Moaddel R, Maleta KM, Ordiz MI, Kraemer K, Khadeer M, Ferrucci L, Manary MJ
Sci Rep. 2016 Jun 13; 628009. doi: 10.1038/srep28009.

PMID:
    27294788
    [PubMed - in process]
Related citations


An important chapter in the infection-malnutrition story.
Trehan I, Manary MJ
Lancet Glob Health. 2016 Jul; 4(7)e430-1. doi: 10.1016/S2214-109X(16)30110-3.

PMID:
    27289200
    [PubMed - in process]
Related citations


The association of serum choline with linear growth failure in young children from rural Malawi.
Semba RD, Zhang P, Gonzalez-Freire M, Moaddel R, Trehan I, Maleta KM, Ordiz MI, Ferrucci L, Manary MJ
Am J Clin Nutr. 2016 Jul; 104(1)191-7. doi: 10.3945/ajcn.115.129684.

PMID:
    27281303
    [PubMed - indexed for MEDLINE]
Related citations


Child Stunting is Associated with Low Circulating Essential Amino Acids.
Semba RD, Shardell M, Sakr Ashour FA, Moaddel R, Trehan I, Maleta KM, Ordiz MI, Kraemer K, Khadeer MA, Ferrucci L, Manary MJ
EBioMedicine. 2016 Apr; 6246-252. doi: 10.1016/j.ebiom.2016.02.030.

PMID:
    27211567
    [PubMed - indexed for MEDLINE]
Related citations


Droplet digital PCR quantifies host inflammatory transcripts in feces reliably and reproducibly.
Stauber J, Shaikh N, Ordiz MI, Tarr PI, Manary MJ
Cell Immunol. 2016 May; 30343-9. doi: 10.1016/j.cellimm.2016.03.007.

PMID:
    27063479
    [PubMed - indexed for MEDLINE]
Related citations


Environmental Enteric Dysfunction Includes a Broad Spectrum of Inflammatory Responses and Epithelial Repair Processes.
Yu J, Ordiz MI, Stauber J, Shaikh N, Trehan I, Barnell E, Head RD, Maleta K, Tarr PI, Manary MJ
Cell Mol Gastroenterol Hepatol. 2016 Feb; 2(2)158-174.e1.

PMID:
    26973864
    [PubMed]
Related citations