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Mark J. Manary, MD

Helene B Roberson Prof of Pediatrics
Director, Global Harvest Alliance,

Specialty Areas

Pediatric Emergency Medicine

Board Certifications

Pediatrics
Pediatric Emergency Medicine

Hospital Affiliations

St. Louis Children's Hospital

Areas of Clinical Interest

Nutrition, developing countries-nutrition, Potassium supplementation, protein kenetics, kwashiorkor

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: First Floor
Office Phone: 314-454-6111

Education

Education

Residency: Pediatrics, St. Louis Children's Hospital, St. Louis, Missouri
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1982
B.S.: Chemistry & Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 1977

Publication & Research

Publication & Research

Amoxicillin for Severe Acute Malnutrition in Children.
Trehan I, Schechtman KB, Manary MJ
N Engl J Med. 2016 Jul 14; 375(2)191. doi: 10.1056/NEJMc1605388#SA2.

PMID:
    27410940
    [PubMed - indexed for MEDLINE]
Related citations


Environmental Enteric Dysfunction is Associated with Poor Linear Growth and Can be Identified by Host Fecal mRNAs.
Ordiz MI, Shaikh N, Trehan I, Maleta K, Stauber J, Shulman R, Devaraj S, Tarr PI, Manary MJ
J Pediatr Gastroenterol Nutr. 2016 Jun 24;

PMID:
    27347722
    [PubMed - as supplied by publisher]
Related citations


Environmental Enteric Dysfunction is Associated with Altered Bile Acid Metabolism.
Semba RD, Gonzalez-Freire M, Moaddel R, Trehan I, Maleta KM, Khadeer M, Ordiz MI, Ferrucci L, Manary MJ
J Pediatr Gastroenterol Nutr. 2016 Jun 17;

PMID:
    27322559
    [PubMed - as supplied by publisher]
Related citations


Metabolic alterations in children with environmental enteric dysfunction.
Semba RD, Shardell M, Trehan I, Moaddel R, Maleta KM, Ordiz MI, Kraemer K, Khadeer M, Ferrucci L, Manary MJ
Sci Rep. 2016 Jun 13; 628009. doi: 10.1038/srep28009.

PMID:
    27294788
    [PubMed - in process]
Related citations


An important chapter in the infection-malnutrition story.
Trehan I, Manary MJ
Lancet Glob Health. 2016 Jul; 4(7)e430-1. doi: 10.1016/S2214-109X(16)30110-3.

PMID:
    27289200
    [PubMed - in process]
Related citations


The association of serum choline with linear growth failure in young children from rural Malawi.
Semba RD, Zhang P, Gonzalez-Freire M, Moaddel R, Trehan I, Maleta KM, Ordiz MI, Ferrucci L, Manary MJ
Am J Clin Nutr. 2016 Jul; 104(1)191-7. doi: 10.3945/ajcn.115.129684.

PMID:
    27281303
    [PubMed - in process]
Related citations


Child Stunting is Associated with Low Circulating Essential Amino Acids.
Semba RD, Shardell M, Sakr Ashour FA, Moaddel R, Trehan I, Maleta KM, Ordiz MI, Kraemer K, Khadeer MA, Ferrucci L, Manary MJ
EBioMedicine. 2016 Apr; 6246-52. doi: 10.1016/j.ebiom.2016.02.030.

PMID:
    27211567
    [PubMed - in process]
Related citations


Droplet digital PCR quantifies host inflammatory transcripts in feces reliably and reproducibly.
Stauber J, Shaikh N, Ordiz MI, Tarr PI, Manary MJ
Cell Immunol. 2016 May; 30343-9. doi: 10.1016/j.cellimm.2016.03.007.

PMID:
    27063479
    [PubMed - in process]
Related citations


Environmental Enteric Dysfunction Includes a Broad Spectrum of Inflammatory Responses and Epithelial Repair Processes.
Yu J, Ordiz MI, Stauber J, Shaikh N, Trehan I, Barnell E, Head RD, Maleta K, Tarr PI, Manary MJ
Cell Mol Gastroenterol Hepatol. 2016 Feb; 2(2)158-174.e1.

PMID:
    26973864
    [PubMed]
Related citations


New insights into environmental enteric dysfunction.
Trehan I, Kelly P, Shaikh N, Manary MJ
Arch Dis Child. 2016 Aug; 101(8)741-4. doi: 10.1136/archdischild-2015-309534.

PMID:
    26933151
    [PubMed - in process]
Related citations


Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children.
Blanton LV, Charbonneau MR, Salih T, Barratt MJ, Venkatesh S, Ilkaveya O, Subramanian S, Manary MJ, Trehan I, Jorgensen JM, Fan YM, Henrissat B, Leyn SA, Rodionov DA, Osterman AL, Maleta KM, Newgard CB, Ashorn P, Dewey KG, Gordon JI
Science. 2016 Feb 19; 351(6275)pii: aad3311. doi: 10.1126/science.aad3311.

PMID:
    26912898
    [PubMed - indexed for MEDLINE]
Related citations


Including whey protein and whey permeate in ready-to-use supplementary food improves recovery rates in children with moderate acute malnutrition: a randomized, double-blind clinical trial.
Stobaugh HC, Ryan KN, Kennedy JA, Grise JB, Crocker AH, Thakwalakwa C, Litkowski PE, Maleta KM, Manary MJ, Trehan I
Am J Clin Nutr. 2016 Mar; 103(3)926-33. doi: 10.3945/ajcn.115.124636.

PMID:
    26864368
    [PubMed - indexed for MEDLINE]
Related citations


How maternal malnutrition affects linear growth and development in the offspring.
Papathakis PC, Singh LN, Manary MJ
Mol Cell Endocrinol. 2016 Jan 26; pii: S0303-7207(16)30025-9. doi: 10.1016/j.mce.2016.01.024.

PMID:
    26820126
    [PubMed - as supplied by publisher]
Related citations


Acceptability of locally produced ready-to-use therapeutic foods in Ethiopia, Ghana, Pakistan and India.
Weber JM, Ryan KN, Tandon R, Mathur M, Girma T, Steiner-Asiedu M, Saalia F, Zaidi S, Soofi S, Okos M, Vosti SA, Manary MJ
Matern Child Nutr. 2016 Jan 18; doi: 10.1111/mcn.12250.

PMID:
    26776270
    [PubMed - as supplied by publisher]
Related citations


Common beans and cowpeas as complementary foods to reduce environmental enteric dysfunction and stunting in Malawian children: study protocol for two randomized controlled trials.
Trehan I, Benzoni NS, Wang AZ, Bollinger LB, Ngoma TN, Chimimba UK, Stephenson KB, Agapova SE, Maleta KM, Manary MJ
Trials. 2015 Nov 14; 16520. doi: 10.1186/s13063-015-1027-0.

PMID:
    26578308
    [PubMed - indexed for MEDLINE]
Related citations


Severe and Moderate Acute Malnutrition Can Be Successfully Managed with an Integrated Protocol in Sierra Leone.
Maust A, Koroma AS, Abla C, Molokwu N, Ryan KN, Singh L, Manary MJ
J Nutr. 2015 Nov; 145(11)2604-9. doi: 10.3945/jn.115.214957.

PMID:
    26423737
    [PubMed - indexed for MEDLINE]
Related citations


The effect of dietary resistant starch type 2 on the microbiota and markers of gut inflammation in rural Malawi children.
Ordiz MI, May TD, Mihindukulasuriya K, Martin J, Crowley J, Tarr PI, Ryan K, Mortimer E, Gopalsamy G, Maleta K, Mitreva M, Young G, Manary MJ
Microbiome. 2015 Sep 3; 337. doi: 10.1186/s40168-015-0102-9.

PMID:
    26334878
    [PubMed - indexed for MEDLINE]
Related citations


Effect of emulsifier and viscosity on oil separation in ready-to-use therapeutic food.
Ordiz MI, Ryan KN, Cimo ED, Stoner ME, Loehnig ME, Manary MJ
Int J Food Sci Nutr. 2015; 66(6)642-8. doi: 10.3109/09637486.2015.1077784.

PMID:
    26299733
    [PubMed - indexed for MEDLINE]
Related citations


Resistant starch does not affect zinc homeostasis in rural Malawian children.
May T, Westcott C, Thakwalakwa C, Ordiz MI, Maleta K, Westcott J, Ryan K, Hambidge KM, Miller LV, Young G, Mortimer E, Manary MJ, Krebs NF
J Trace Elem Med Biol. 2015 Apr; 3043-8. doi: 10.1016/j.jtemb.2015.01.005.

PMID:
    25744509
    [PubMed - indexed for MEDLINE]
Related citations


Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy.
Kau AL, Planer JD, Liu J, Rao S, Yatsunenko T, Trehan I, Manary MJ, Liu TC, Stappenbeck TS, Maleta KM, Ashorn P, Dewey KG, Houpt ER, Hsieh CS, Gordon JI
Sci Transl Med. 2015 Feb 25; 7(276)276ra24. doi: 10.1126/scitranslmed.aaa4877.

PMID:
    25717097
    [PubMed - indexed for MEDLINE]
Related citations