FollowMyHealth Patient Portal

Faculty Physicians

Mark J. Manary, MD

Helene B Roberson Prof of Pediatrics
Director, Global Harvest Alliance,

Specialty Areas

Pediatric Emergency Medicine

Board Certifications

Pediatrics
Pediatric Emergency Medicine

Areas of Clinical Interest

Nutrition, developing countries-nutrition, Potassium supplementation, protein kenetics, kwashiorkor

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: First Floor
Office Phone: 314-454-6111

Education

Education

Residency: Pediatrics, St. Louis Children's Hospital, St. Louis, Missouri
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1982
B.S.: Chemistry & Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 1977

Publication & Research

Publication & Research

Drug resistance genomics of the antimalarial drug artemisinin.
Winzeler EA, Manary MJ
Genome Biol. 2014 Nov 25; 15(11)544. doi: 10.1186/s13059-014-0544-6.

PMID:
    25470531
    [PubMed - indexed for MEDLINE]
Related citations


Management of severe acute malnutrition in low-income and middle-income countries.
Trehan I, Manary MJ
Arch Dis Child. 2015 Mar; 100(3)283-7. doi: 10.1136/archdischild-2014-306026.

PMID:
    25421910
    [PubMed - indexed for MEDLINE]
Related citations


A comprehensive linear programming tool to optimize formulations of ready-to-use therapeutic foods: an application to Ethiopia.
Ryan KN, Adams KP, Vosti SA, Ordiz MI, Cimo ED, Manary MJ
Am J Clin Nutr. 2014 Dec; 100(6)1551-8. doi: 10.3945/ajcn.114.090670.

PMID:
    25411290
    [PubMed - indexed for MEDLINE]
Related citations


Multiple micronutrient supplementation transiently ameliorates environmental enteropathy in Malawian children aged 12-35 months in a randomized controlled clinical trial.
Smith HE, Ryan KN, Stephenson KB, Westcott C, Thakwalakwa C, Maleta K, Cheng JY, Brenna JT, Shulman RJ, Trehan I, Manary MJ
J Nutr. 2014 Dec; 144(12)2059-65. doi: 10.3945/jn.114.201673.

PMID:
    25411039
    [PubMed - indexed for MEDLINE]
Related citations


Zinc deficiency in children with environmental enteropathy-development of new strategies: report from an expert workshop.
Young GP, Mortimer EK, Gopalsamy GL, Alpers DH, Binder HJ, Manary MJ, Ramakrishna BS, Brown IL, Brewer TG
Am J Clin Nutr. 2014 Oct; 100(4)1198-207. doi: 10.3945/ajcn.113.075036.

PMID:
    25240082
    [PubMed - indexed for MEDLINE]
Related citations


A high resolution case study of a patient with recurrent Plasmodium vivax infections shows that relapses were caused by meiotic siblings.
Bright AT, Manary MJ, Tewhey R, Arango EM, Wang T, Schork NJ, Yanow SK, Winzeler EA
PLoS Negl Trop Dis. 2014 Jun; 8(6)e2882. doi: 10.1371/journal.pntd.0002882.

PMID:
    24901334
    [PubMed - indexed for MEDLINE]
Related citations


Zinc or albendazole attenuates the progression of environmental enteropathy: a randomized controlled trial.
Ryan KN, Stephenson KB, Trehan I, Shulman RJ, Thakwalakwa C, Murray E, Maleta K, Manary MJ
Clin Gastroenterol Hepatol. 2014 Sep; 12(9)1507-13.e1. doi: 10.1016/j.cgh.2014.01.024.

PMID:
    24462483
    [PubMed - indexed for MEDLINE]
Related citations


Targeting Plasmodium PI(4)K to eliminate malaria.
McNamara CW, Lee MC, Lim CS, Lim SH, Roland J, Nagle A, Simon O, Yeung BK, Chatterjee AK, McCormack SL, Manary MJ, Zeeman AM, Dechering KJ, Kumar TR, Henrich PP, Gagaring K, Ibanez M, Kato N, Kuhen KL, Fischli C, Rottmann M, Plouffe DM, Bursulaya B, Meister S, Rameh L, Trappe J, Haasen D, Timmerman M, Sauerwein RW, Suwanarusk R, Russell B, Renia L, Nosten F, Tully DC, Kocken CH, Glynne RJ, Bodenreider C, Fidock DA, Diagana TT, Winzeler EA
Nature. 2013 Dec 12; 504(7479)248-53. doi: 10.1038/nature12782.

PMID:
    24284631
    [PubMed - indexed for MEDLINE]
Related citations


Review of the safety and efficacy of vitamin A supplementation in the treatment of children with severe acute malnutrition.
Iannotti LL, Trehan I, Manary MJ
Nutr J. 2013 Sep 12; 12125. doi: 10.1186/1475-2891-12-125.

PMID:
    24028603
    [PubMed - indexed for MEDLINE]
Related citations


Antibiotics for uncomplicated severe malnutrition.
Trehan I, Maleta KM, Manary MJ
N Engl J Med. 2013 Jun 20; 368(25)2436-7. doi: 10.1056/NEJMc1304407.

PMID:
    23782188
    [PubMed - indexed for MEDLINE]
Related citations


Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families.
Bopp SE, Manary MJ, Bright AT, Johnston GL, Dharia NV, Luna FL, McCormack S, Plouffe D, McNamara CW, Walker JR, Fidock DA, Denchi EL, Winzeler EA
PLoS Genet. 2013; 9(2)e1003293. doi: 10.1371/journal.pgen.1003293.

PMID:
    23408914
    [PubMed - indexed for MEDLINE]
Related citations


Gut microbiomes of Malawian twin pairs discordant for kwashiorkor.
Smith MI, Yatsunenko T, Manary MJ, Trehan I, Mkakosya R, Cheng J, Kau AL, Rich SS, Concannon P, Mychaleckyj JC, Liu J, Houpt E, Li JV, Holmes E, Nicholson J, Knights D, Ursell LK, Knight R, Gordon JI
Science. 2013 Feb 1; 339(6119)548-54. doi: 10.1126/science.1229000.

PMID:
    23363771
    [PubMed - indexed for MEDLINE]
Related citations


Antibiotics as part of the management of severe acute malnutrition.
Trehan I, Goldbach HS, LaGrone LN, Meuli GJ, Wang RJ, Maleta KM, Manary MJ
N Engl J Med. 2013 Jan 31; 368(5)425-35. doi: 10.1056/NEJMoa1202851.

PMID:
    23363496
    [PubMed - indexed for MEDLINE]
Related citations


Discovery of STL polyomavirus, a polyomavirus of ancestral recombinant origin that encodes a unique T antigen by alternative splicing.
Lim ES, Reyes A, Antonio M, Saha D, Ikumapayi UN, Adeyemi M, Stine OC, Skelton R, Brennan DC, Mkakosya RS, Manary MJ, Gordon JI, Wang D
Virology. 2013 Feb 20; 436(2)295-303. doi: 10.1016/j.virol.2012.12.005.

PMID:
    23276405
    [PubMed - indexed for MEDLINE]
Related citations


Children successfully treated for moderate acute malnutrition remain at risk for malnutrition and death in the subsequent year after recovery.
Chang CY, Trehan I, Wang RJ, Thakwalakwa C, Maleta K, Deitchler M, Manary MJ
J Nutr. 2013 Feb; 143(2)215-20. doi: 10.3945/jn.112.168047.

PMID:
    23256140
    [PubMed - indexed for MEDLINE]
Related citations


Investigation of food acceptability and feeding practices for lipid nutrient supplements and blended flours used to treat moderate malnutrition.
Wang RJ, Trehan I, LaGrone LN, Weisz AJ, Thakwalakwa CM, Maleta KM, Manary MJ
J Nutr Educ Behav. 2013 May-Jun; 45(3)258-63. doi: 10.1016/j.jneb.2012.08.001.

PMID:
    23246175
    [PubMed - indexed for MEDLINE]
Related citations


Identification of MW polyomavirus, a novel polyomavirus in human stool.
Siebrasse EA, Reyes A, Lim ES, Zhao G, Mkakosya RS, Manary MJ, Gordon JI, Wang D
J Virol. 2012 Oct; 86(19)10321-6. doi: 10.1128/JVI.01210-12.

PMID:
    22740408
    [PubMed - indexed for MEDLINE]
Related citations


Abnormal gut integrity is associated with reduced linear growth in rural Malawian children.
Weisz AJ, Manary MJ, Stephenson K, Agapova S, Manary FG, Thakwalakwa C, Shulman RJ, Manary MJ
J Pediatr Gastroenterol Nutr. 2012 Dec; 55(6)747-50. doi: 10.1097/MPG.0b013e3182650a4d.

PMID:
    22732897
    [PubMed - indexed for MEDLINE]
Related citations


Human gut microbiome viewed across age and geography.
Yatsunenko T, Rey FE, Manary MJ, Trehan I, Dominguez-Bello MG, Contreras M, Magris M, Hidalgo G, Baldassano RN, Anokhin AP, Heath AC, Warner B, Reeder J, Kuczynski J, Caporaso JG, Lozupone CA, Lauber C, Clemente JC, Knights D, Knight R, Gordon JI
Nature. 2012 May 9; 486(7402)222-7. doi: 10.1038/nature11053.

PMID:
    22699611
    [PubMed - indexed for MEDLINE]
Related citations


Retention during processing and bioaccessibility of β-carotene in high β-carotene transgenic cassava root.
Failla ML, Chitchumroonchokchai C, Siritunga D, De Moura FF, Fregene M, Manary MJ, Sayre RT
J Agric Food Chem. 2012 Apr 18; 60(15)3861-6. doi: 10.1021/jf204958w.

PMID:
    22458891
    [PubMed - indexed for MEDLINE]
Related citations