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Mario Castro, MD, MPH, FCCP

Professor, Medicine and Pediatrics
Division of Pulmonary and Critical Care Medicine

Specialty Areas

Pulmonary Disease
Asthma
Lung Cancer

Board Certifications

Pulmonary Disease
Internal Medicine
Critical Care Medicine

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital

Areas of Clinical Interest

Asthma and related allergic disease, COPD, emphysema, chronic bronchitis, interstital lung disease, idiopathic pulmonary fibrosis, sarcoidosis, chronic cough, unexplained shortness of breath, vasculitis, chronic lung infections, pulmonary hypertension, bronchiectasis.

  • Maps & Directions
  • Education
  • Publication & Research
  • Financial Disclosures

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-454-8917

Education

Education

Graduate: Public Health, St. Louis University School of Public Health, St. Louis, Missouri 1998
Fellowship: Pulmonary/Critical Care, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1994
Residency: Internal Medicine, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1991
Medical Degree: University Of Missouri, Kansas City, Missouri 1988

Publication & Research

Publication & Research

Disease and economic burdens of dengue.
Castro MC, Wilson ME, Bloom DE
Lancet Infect Dis. 2017 Feb 6; pii: S1473-3099(16)30545-X. doi: 10.1016/S1473-3099(16)30545-X.

PMID:
    28185869
    [PubMed - as supplied by publisher]
Related citations


Cytogeography of the subalpine marsh marigold polyploid complex (<i>Caltha leptosepala</i> s.l., Ranunculaceae).
Wefferling KM, Castro S, Loureiro J, Castro M, Tavares D, Hoot SB
Am J Bot. 2017 Feb 9; doi: 10.3732/ajb.1600365.

PMID:
    28183833
    [PubMed - as supplied by publisher]
Related citations


Energy and protein requirements of crossbred (Holstein × Gyr) growing bulls.
Oss DB, Machado FS, Tomich TR, Pereira LG, Campos MM, Castro MM, da Silva TE, Marcondes MI
J Dairy Sci. 2017 Feb 1; pii: S0022-0302(17)30084-X. doi: 10.3168/jds.2016-11414.

PMID:
    28161164
    [PubMed - as supplied by publisher]
Related citations


Impact of the Japanese 5S management method on patients' and caretakers' satisfaction: a quasi-experimental study in Senegal.
Kanamori S, Castro MC, Sow S, Matsuno R, Cissokho A, Jimba M
Glob Health Action. 2016 Jan; 9(1)32852. doi: 10.3402/gha.v9.32852.

PMID:
    28157031
    [PubMed - in process]
Related citations


RA Differentiation Enhances Dopaminergic Features, Changes Redox Parameters, and Increases Dopamine Transporter Dependency in 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells.
Lopes FM, da Motta LL, De Bastiani MA, Pfaffenseller B, Aguiar BW, de Souza LF, Zanatta G, Vargas DM, Schönhofen P, Londero GF, de Medeiros LM, Freire VN, Dafre AL, Castro MA, Parsons RB, Klamt F
Neurotox Res. 2017 Feb 2; doi: 10.1007/s12640-016-9699-0.

PMID:
    28155214
    [PubMed - as supplied by publisher]
Related citations


Biomarkers in pulmonary hypertension: An ongoing quest for better outcomes.
Castro MG
Rev Port Cardiol. 2017 Feb; 36(2)127-128. doi: 10.1016/j.repc.2016.12.005.

PMID:
    28153631
    [PubMed - in process]
Related citations


Quantitative computed tomography imaging-based clustering differentiates asthmatic subgroups with distinctive clinical phenotypes.
Choi S, Hoffman EA, Wenzel SE, Castro M, Fain S, Jarjour N, Schiebler ML, Chen K, Lin CL, National Heart, Lung and Blood Institute’s Severe Asthma Research Program.
J Allergy Clin Immunol. 2017 Jan 28; pii: S0091-6749(17)30146-X. doi: 10.1016/j.jaci.2016.11.053.

PMID:
    28143694
    [PubMed - as supplied by publisher]
Related citations


Immunosuppressive Myeloid Cells' Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy.
Kamran N, Kadiyala P, Saxena M, Candolfi M, Li Y, Moreno-Ayala MA, Raja N, Shah D, Lowenstein PR, Castro MG
Mol Ther. 2017 Jan 4; 25(1)232-248. doi: 10.1016/j.ymthe.2016.10.003.

PMID:
    28129117
    [PubMed - in process]
Related citations


Invasive species in the Northeastern and Southwestern Atlantic Ocean: A review.
Castro MC, Fileman TW, Hall-Spencer JM
Mar Pollut Bull. 2017 Jan 23; pii: S0025-326X(16)31053-0. doi: 10.1016/j.marpolbul.2016.12.048.

PMID:
    28126398
    [PubMed - as supplied by publisher]
Related citations


Bibliometric Indicators of the Zika Outbreak.
Albuquerque PC, Castro MJ, Santos-Gandelman J, Oliveira AC, Peralta JM, Rodrigues ML
PLoS Negl Trop Dis. 2017 Jan 19; 11(1)e0005132. doi: 10.1371/journal.pntd.0005132.

PMID:
    28103326
    [PubMed - in process]
Related citations


Zika rash and increased risk of congenital brain abnormalities - Authors' reply.
Victora CG, Castro MC, França GV, Schuler-Faccini L, Barros FC
Lancet. 2017 Jan 14; 389(10065)152. doi: 10.1016/S0140-6736(17)30015-6.

PMID:
    28102136
    [PubMed - in process]
Related citations


Corrigendum: Premature changes in neuronal excitability account for hippocampal network impairment and autistic-like behavior in neonatal BTBR T+tf/J mice.
Cellot G, Maggi L, Castro MA, Catalano M, Migliore R, Migliore M, Scattoni ML, Calamandrei G, Cherubini E
Sci Rep. 2017 Jan 9; 739726. doi: 10.1038/srep39726.

PMID:
    28067244
    [PubMed - in process]
Related citations


Using imaging as a biomarker for asthma.
Trivedi A, Hall C, Hoffman EA, Woods JC, Gierada DS, Castro M
J Allergy Clin Immunol. 2017 Jan; 139(1)1-10. doi: 10.1016/j.jaci.2016.11.009.

PMID:
    28065276
    [PubMed - in process]
Related citations


Embryotoxic effects of Poincianella ( Caesalpinia) pyramidalis leaves on pregnant rats.
Câmara AC, Gadelha IC, Castro MB, Medeiros RM, Riet-Correa F, Soto-Blanco B
J Vet Diagn Invest. 2017 Jan 1; 1040638716682564. doi: 10.1177/1040638716682564.

PMID:
    28064563
    [PubMed - as supplied by publisher]
Related citations


Mutated Chromatin Regulatory Factors as Tumor Drivers in Cancer.
Koschmann C, Nunez FJ, Mendez F, Brosnan-Cashman JA, Meeker AK, Lowenstein PR, Castro MG
Cancer Res. 2017 Jan 15; 77(2)227-233. doi: 10.1158/0008-5472.CAN-16-2301.

PMID:
    28062403
    [PubMed - in process]
Related citations


Matrix Metalloproteinase Activity in Infections by an Encephalitic Virus, Mouse Adenovirus Type 1.
Ashley SL, Pretto CD, Stier MT, Kadiyala P, Castro-Jorge L, Hsu TH, Doherty R, Carnahan KE, Castro MG, Lowenstein PR, Spindler KR
J Virol. 2017 Jan 4; pii: JVI.01412-16. doi: 10.1128/JVI.01412-16.

PMID:
    28053109
    [PubMed - as supplied by publisher]
Related citations


Egg white-derived peptides prevent male reproductive dysfunction induced by mercury in rats.
Rizzetti DA, Martinez CS, Escobar AG, da Silva TM, Uranga-Ocio JA, Peçanha FM, Vassallo DV, Castro MM, Wiggers GA
Food Chem Toxicol. 2017 Feb; 100253-264. doi: 10.1016/j.fct.2016.12.038.

PMID:
    28043836
    [PubMed - in process]
Related citations


Intestinal Serotonin Transporter Inhibition by Toll-Like Receptor 2 Activation. A Feedback Modulation.
Latorre E, Layunta E, Grasa L, Castro M, Pardo J, Gomollón F, Alcalde AI, Mesonero JE
PLoS One. 2016 Dec 29; 11(12)e0169303. doi: 10.1371/journal.pone.0169303.

PMID:
    28033388
    [PubMed - in process]
Related citations


[Erratum to: "Breast cancer screening: On our way to the future" [Bull. Cancer 103 (2016) 753-763]].
Delaloge S, Bachelot T, Bidard FC, Espie M, Brain E, Bonnefoi H, Gligorov J, Dalenc F, Hardy-Bessard AC, Azria D, Jacquin JP, Lemonnier J, Jacot W, Goncalves A, Coutant C, Ganem G, Petit T, Penault-Llorca F, Debled M, Campone M, Levy C, Coudert B, Lortholary A, Venat-Bouvet L, Grenier J, Bourgeois H, Asselain B, Arvis J, Castro M, Tardivon A, Cox DG, Arveux P, Balleyguier C, André F, Rouzier R, Intergroupe national de recherche sur le cancer du sein Unicancer (UCBG).
Bull Cancer. 2016 Oct 28; pii: S0007-4551(16)30276-4. doi: 10.1016/j.bulcan.2016.10.009.

PMID:
    28029350
    [PubMed - as supplied by publisher]
Related citations


Proposal for a breakfast quality index for brazilian population: Rationale and application in the Brazilian National Dietary Survey.
Pereira JL, Castro MA, Hopkins S, Gugger C, Fisberg RM, Fisberg M
Appetite. 2017 Apr 1; 11112-22. doi: 10.1016/j.appet.2016.12.023.

PMID:
    28007489
    [PubMed - in process]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2015.

Company Name: Boehringer Ingelheim

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $10,001 - $25,000

Reporting Date: May 01, 2016


Company Name: Genentech

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $25,001 - $50,000

Reporting Date: May 01, 2016


Company Name: Sparo

Royalties:

Equity: Yes

Consulting/Advisory Board:

Speaker Fees:

Reporting Date: May 01, 2016


Company Name: Teva

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $25,001 - $50,000

Reporting Date: May 01, 2016