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Mario Castro, MD, MPH, FCCP

Professor, Medicine and Pediatrics
Division of Pulmonary and Critical Care Medicine

Specialty Areas

Pulmonary Disease
Asthma
Lung Cancer

Board Certifications

Pulmonary Disease
Internal Medicine
Critical Care Medicine

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital

Areas of Clinical Interest

Asthma and related allergic disease, COPD, emphysema, chronic bronchitis, interstital lung disease, idiopathic pulmonary fibrosis, sarcoidosis, chronic cough, unexplained shortness of breath, vasculitis, chronic lung infections, pulmonary hypertension, bronchiectasis.

  • Maps & Directions
  • Education
  • Publication & Research
  • Financial Disclosures

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-454-8917

Education

Education

Graduate: Public Health, St. Louis University School of Public Health, St. Louis, Missouri 1998
Fellowship: Pulmonary/Critical Care, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1994
Residency: Internal Medicine, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1991
Medical Degree: University Of Missouri, Kansas City, Missouri 1988

Publication & Research

Publication & Research

Providing antenatal corticosteroids for preterm birth: a quality improvement initiative in Cambodia and the Philippines.
Smith JM, Gupta S, Williams E, Brickson K, Ly Sotha K, Tep N, Calibo A, Castro MC, Marinduque B, Hathaway M
Int J Qual Health Care. 2016 Sep 10;

PMID:
    27614015
    [PubMed - as supplied by publisher]
Related citations


Treatment for severe eosinophilic asthma-consistent effect of anti-interleukin-5 antibodies?
Castro M, Bacharier LB
Lancet. 2016 Sep 2; pii: S0140-6736(16)31537-9. doi: 10.1016/S0140-6736(16)31537-9.

PMID:
    27609409
    [PubMed - as supplied by publisher]
Related citations


A Window on the Study of Aversive Instrumental Learning: Strains, Performance, Neuroendocrine, and Immunologic Systems.
de Oliveira CC, Gouveia FV, de Castro MC, Kuroki MA, Dos Santos LC, Fonoff ET, Teixeira MJ, Otoch JP, Martinez RC
Front Behav Neurosci. 2016; 10162. doi: 10.3389/fnbeh.2016.00162.

PMID:
    27605910
    [PubMed]
Related citations


Zeolite Beta Formation from Clear Sols: Silicate Speciation, Particle Formation and Crystallization Monitored by Complementary Analysis Methods.
Castro M, Haouas M, Lim I, Bongard HJ, Schüth F, Taulelle F, Karlsson G, Alfredsson V, Breyneart E, Kirschhock CE, Schmidt W
Chemistry. 2016 Sep 7; doi: 10.1002/chem.201600511.

PMID:
    27603448
    [PubMed - as supplied by publisher]
Related citations


Culex quinquefasciatus from Rio de Janeiro Is Not Competent to Transmit the Local Zika Virus.
Fernandes RS, Campos SS, Ferreira-de-Brito A, Miranda RM, Barbosa da Silva KA, Castro MG, Raphael LM, Brasil P, Failloux AB, Bonaldo MC, Lourenço-de-Oliveira R
PLoS Negl Trop Dis. 2016 Sep; 10(9)e0004993. doi: 10.1371/journal.pntd.0004993.

PMID:
    27598421
    [PubMed - in process]
Related citations


Chronic Glucocorticoid-Rich Milieu and Liver Dysfunction.
Villagarcía HG, Sabugo V, Castro MC, Schinella G, Castrogiovanni D, Spinedi E, Massa ML, Francini F
Int J Endocrinol. 2016; 20167838290. doi: 10.1155/2016/7838290.

PMID:
    27597864
    [PubMed]
Related citations


Quality of Life and Functional Independence in Patients with Osteoarthritis of the Knee.
Araujo IL, Castro MC, Daltro C, Matos MA
Knee Surg Relat Res. 2016 Sep; 28(3)219-24. doi: 10.5792/ksrr.2016.28.3.219.

PMID:
    27595076
    [PubMed]
Related citations


Self-assembled 3D spheroids and hollow-fibre bioreactors improve MSC-derived hepatocyte-like cell maturation in vitro.
Cipriano M, Freyer N, Knöspel F, Oliveira NG, Barcia R, Cruz PE, Cruz H, Castro M, Santos JM, Zeilinger K, Miranda JP
Arch Toxicol. 2016 Sep 2;

PMID:
    27590069
    [PubMed - as supplied by publisher]
Related citations


Photodynamically dealing with bisphosphonate-related osteonecrosis of the jaw: successful case reports.
de Castro MS, Ribeiro NV Jr, de Carli ML, Costa Pereira AA, Sperandio FF, Costa Hanemann JA
Photodiagnosis Photodyn Ther. 2016 Aug 29; pii: S1572-1000(16)30109-0. doi: 10.1016/j.pdpdt.2016.08.007.

PMID:
    27585753
    [PubMed - as supplied by publisher]
Related citations


Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma.
Koschmann C, Zamler D, MacKay A, Robinson D, Wu YM, Doherty R, Marini B, Tran D, Garton H, Muraszko K, Robertson P, Leonard M, Zhao L, Bixby D, Peterson L, Camelo-Piragua S, Jones C, Mody R, Lowenstein PR, Castro MG
Oncotarget. 2016 Aug 25; doi: 10.18632/oncotarget.11602.

PMID:
    27582545
    [PubMed - as supplied by publisher]
Related citations


Comorbidities in patients with Primary Sjögren's Syndrome and Systemic Lupus Erythematosus: A comparative registries-based study.
Rúa-Figueroa I, de Castro MF, Andreu JL, Sanchez-Piedra C, Martínez-Taboada V, Olivé A, López-Longo J, Rosas J, Galindo M, Calvo-Alén J, Fernández-Nebro A, Alonso F, Rodríguez-Lozano B, García Vadillo JA, Menor R, Narváez FJ, Erausquin C, García-Aparicio Á, Tomero E, Manrique-Arija S, Horcada L, Uriarte E, Gil S, Blanco R, López-González R, Boteanu A, Freire M, Galisteo C, Rodríguez-Gómez M, Díez-Álvarez E, Pego-Reigosa JM, IISGS (Instituto de Investigación Sanitaria Galicia Sur), SJOGRENSER and RELESSER researchers and EAS-SER GROUP
Arthritis Care Res (Hoboken). 2016 Aug 26; doi: 10.1002/acr.23015.

PMID:
    27564390
    [PubMed - as supplied by publisher]
Related citations


Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior. Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells.
Wilson TJ, Zamler DB, Doherty R, Castro MG, Lowenstein PR
Oncotarget. 2016 Aug 24; doi: 10.18632/oncotarget.11589.

PMID:
    27564115
    [PubMed - as supplied by publisher]
Related citations


Bayesian inference for agreement measures.
Vidal I, de Castro M
J Biopharm Stat. 2016 Aug 25;

PMID:
    27562901
    [PubMed - as supplied by publisher]
Related citations


Clinical course and short-term mortality of cirrhotic patients with infections other than spontaneous bacterial peritonitis.
Fernández J, Acevedo J, Prado V, Mercado M, Castro M, Pavesi M, Arteaga M, Sastre L, Juanola A, Ginès P, Arroyo V
Liver Int. 2016 Aug 25; doi: 10.1111/liv.13239.

PMID:
    27558198
    [PubMed - as supplied by publisher]
Related citations


Performance and health of Holstein calves fed different levels of milk fortified with symbiotic complex containing pre- and probiotics.
Marcondes MI, Pereira TR, Chagas JC, Filgueiras EA, Castro MM, Costa GP, Sguizzato AL, Sainz RD
Trop Anim Health Prod. 2016 Aug 24;

PMID:
    27557699
    [PubMed - as supplied by publisher]
Related citations


Inflammatory and Co-Morbid Features of Patients with Severe Asthma and Frequent Exacerbations.
Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, Fajt M, Fitzpatrick AM, Gaffin J, Gaston B, Hastie AT, Hawkins GA, Holguin F, Irani AM, Israel E, Levy BD, Ly N, Meyers DA, Moore WC, Myers R, Opina MT, Peters MC, Schiebler ML, Sorkness RL, Teague WG, Wenzel SE, Woodruff PG, Mauger DT, Fahy JV, Jarjour NN, National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators
Am J Respir Crit Care Med. 2016 Aug 24;

PMID:
    27556234
    [PubMed - as supplied by publisher]
Related citations


Safety and immunogenicity of the M72/AS01E candidate tuberculosis vaccine in adults with tuberculosis: A phase II randomised study.
Gillard P, Yang PC, Danilovits M, Su WJ, Cheng SL, Pehme L, Bollaerts A, Jongert E, Moris P, Ofori-Anyinam O, Demoitié MA, Castro M
Tuberculosis (Edinb). 2016 Sep; 100118-27. doi: 10.1016/j.tube.2016.07.005.

PMID:
    27553419
    [PubMed - in process]
Related citations


Sensor fault detection and isolation system for a condensation process.
Castro MA, Escobar RF, Torres L, Aguilar JF, Hernández JA, Olivares-Peregrino VH
ISA Trans. 2016 Aug 20; pii: S0019-0578(16)30165-3. doi: 10.1016/j.isatra.2016.08.004.

PMID:
    27553124
    [PubMed - as supplied by publisher]
Related citations


Cathepsin B launches an apoptotic exit effort upon cell death-associated disruption of lysosomes.
de Castro MA, Bunt G, Wouters FS
Cell Death Discov. 2016; 216012. doi: 10.1038/cddiscovery.2016.12.

PMID:
    27551506
    [PubMed]
Related citations


The expression patterns of aquaporin 9, vacuolar H<sup>+</sup>-ATPase, and cytokeratin 5 in the epididymis of the common vampire bat.
Castro MM, Kim B, Hill E, Fialho MC, Puga LC, Freitas MB, Breton S, Machado-Neves M
Histochem Cell Biol. 2016 Aug 22;

PMID:
    27549752
    [PubMed - as supplied by publisher]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2015.

Company Name: Boehringer Ingelheim

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $10,001 - $25,000

Reporting Date: May 01, 2016


Company Name: Genentech

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $25,001 - $50,000

Reporting Date: May 01, 2016


Company Name: Sparo

Royalties:

Equity: Yes

Consulting/Advisory Board:

Speaker Fees:

Reporting Date: May 01, 2016


Company Name: Teva

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $25,001 - $50,000

Reporting Date: May 01, 2016