Mario Castro, MD, MPH, FCCP

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Mario Castro, MD, MPH, FCCP

Professor, Medicine and Pediatrics
Division of Pulmonary and Critical Care Medicine

Specialty Areas

Pulmonary Disease
Asthma
Lung Cancer

Board Certifications

Pulmonary Disease
Internal Medicine
Critical Care Medicine

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital

Areas of Clinical Interest

Asthma and related allergic disease, COPD, emphysema, chronic bronchitis, interstital lung disease, idiopathic pulmonary fibrosis, sarcoidosis, chronic cough, unexplained shortness of breath, vasculitis, chronic lung infections, pulmonary hypertension, bronchiectasis.

Location(s)
Education
Publication & Research
Financial Disclosures

Location(s)

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-454-8917

Education

Graduate: Public Health, St. Louis University School of Public Health, St. Louis, Missouri 1998
Fellowship: Pulmonary/Critical Care, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1994
Residency: Internal Medicine, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1991
Medical Degree: University Of Missouri, Kansas City, Missouri 1988

Publication & Research

Influence of functional moiety in lupane-type triterpenoids in BACE1 inhibition.
Wagle A, Seong SH, Castro MJ, Faraoni MB, Murray AP, Jung HA, Choi JS
Comput Biol Chem. 2019 Aug 14; 83107101. doi: 10.1016/j.compbiolchem.2019.107101.

PMID:
31442708
[PubMed - as supplied by publisher]
Related citations

Evaluating the Impact of Data Representation on EHR-Based Analytic Tasks.
Oh W, Steinbach MS, Castro MR, Peterson KA, Kumar V, Caraballo PJ, Simona GJ
Stud Health Technol Inform. 2019 Aug 21; 264288-292. doi: 10.3233/SHTI190229.

PMID:
31437931
[PubMed - in process]
Related citations

Allogeneic stem cell transplantation improves survival in relapsed Hodgkin lymphoma patients achieving complete remission after salvage treatment.
Rivas MM, Berro M, Prates MV, Yantorno S, Fiad L, Arbelbide JA, Basquiera AL, Ferini GA, García JJ, García PA, Riera L, Jarchum G, Baso A, Real J, Castro M, Jaimovich G, Martinez Rolón J, Foncuberta C, Saba S, Kusminsky G, GATMO (Grupo Argentino de Trasplante de Médula Ósea).
Bone Marrow Transplant. 2019 Aug 21; doi: 10.1038/s41409-019-0640-z.

PMID:
31435033
[PubMed - as supplied by publisher]
Related citations

Personal carbon monoxide exposure, respiratory symptoms, and the potentially modifying roles of sex and HIV infection in rural Uganda: a cohort study.
North CM, MacNaughton P, Lai PS, Vallarino J, Okello S, Kakuhikire B, Tsai AC, Castro MC, Siedner MJ, Allen JG, Christiani DC
Environ Health. 2019 Aug 20; 18(1)73. doi: 10.1186/s12940-019-0517-z.

PMID:
31429759
[PubMed - in process]
Related citations

Antioxidants as Adjuvants in Periodontitis Treatment: A Systematic Review and Meta-Analysis.
Castro MML, Duarte NN, Nascimento PC, Magno MB, Fagundes NCF, Flores-Mir C, Monteiro MC, Rösing CK, Maia LC, Lima RR
Oxid Med Cell Longev. 2019; 20199187978. doi: 10.1155/2019/9187978.

PMID:
31428231
[PubMed - in process]
Related citations

Potential predictive value of cofilin-1 for metastasis occurrence in a small cohort of Argentinian patients with mid-low Breslow thickness melanoma.
Ibañez IL, Grings FM, Bracalente C, Rinflerch AR, Volonteri V, Castro MAA, Klamt F, Durán H
Pathol Res Pract. 2019 Aug 8; 152582. doi: 10.1016/j.prp.2019.152582.

PMID:
31427165
[PubMed - as supplied by publisher]
Related citations

Consumer Avoidance of Insect Containing Foods: Primary Emotions, Perceptions and Sensory Characteristics Driving Consumers Considerations.
Castro M, Chambers E 4th
Foods. 2019 Aug 17; 8(8)pii: E351. doi: 10.3390/foods8080351.

PMID:
31426524
[PubMed]
Related citations

Magnesium-Based Bioactive Composites Processed at Room Temperature.
Castro MM, Lopes DR, Soares RB, Dos Santos DMM, Nunes EHM, Lins VFC, Pereira PHR, Isaac A, Langdon TG, Figueiredo RB
Materials (Basel). 2019 Aug 16; 12(16)pii: E2609. doi: 10.3390/ma12162609.

PMID:
31426290
[PubMed]
Related citations

Clinical significance of the bronchodilator response in children with severe asthma.
Coverstone AM, Bacharier LB, Wilson BS, Fitzpatrick AM, Teague WG, Phipatanakul W, Wenzel SE, Gaston BM, Bleecker ER, Moore WC, Ramratnam S, Jarjour NN, Ly NP, Fahy JV, Mauger DT, Schechtman KB, Yin-DeClue H, Boomer JS, Castro M
Pediatr Pulmonol. 2019 Aug 19; doi: 10.1002/ppul.24473.

PMID:
31424170
[PubMed - as supplied by publisher]
Related citations

Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition.
Ribeiro AG, Almeida SMV, de Oliveira JF, Souza TRCL, Santos KLD, Albuquerque APB, Nogueira MCBL, Carvalho Junior LB, Moura RO, da Silva AC, Pereira VRA, Castro MCAB, Lima MDCA
Eur J Med Chem. 2019 Aug 6; 182111592. doi: 10.1016/j.ejmech.2019.111592.

PMID:
31421632
[PubMed - as supplied by publisher]
Related citations

The "All of Us" Research Program.
All of Us Research Program Investigators., Denny JC, Rutter JL, Goldstein DB, Philippakis A, Smoller JW, Jenkins G, Dishman E
N Engl J Med. 2019 Aug 15; 381(7)668-676. doi: 10.1056/NEJMsr1809937.

PMID:
31412182
[PubMed - in process]
Related citations

Jasonia glutinosa (L.) DC., a traditional herbal medicine, reduces inflammation, oxidative stress and protects the intestinal barrier in a murine model of colitis.
Valero MS, González M, Ramón-Gimenez M, Andrade PB, Moreo E, Les F, Fernandes F, Gómez-Rincón C, Berzosa C, García de Jalón JA, Arruebo MP, Plaza MÁ, Köhler R, López V, Valentão P, Castro M
Inflammopharmacology. 2019 Aug 13; doi: 10.1007/s10787-019-00626-0.

PMID:
31410747
[PubMed - as supplied by publisher]
Related citations

Radiofrequency Ablation Duration per Tumor Volume May Correlate with Overall Survival in Solitary Hepatocellular Carcinoma Patients Treated with RF Ablation Plus Lyso-thermosensitive Liposomal Doxorubicin.
Celik H, Wakim P, Pritchard WF, Castro M, Leonard S, Karanian JW, Dewhirst MW, Lencioni R, Wood BJ
J Vasc Interv Radiol. 2019 Aug 10; pii: S1051-0443(19)30416-6. doi: 10.1016/j.jvir.2019.04.023.

PMID:
31409568
[PubMed - as supplied by publisher]
Related citations

Engineering patient-specific cancer immunotherapies.
Scheetz L, Park KS, Li Q, Lowenstein PR, Castro MG, Schwendeman A, Moon JJ
Nat Biomed Eng. 2019 Aug 12; doi: 10.1038/s41551-019-0436-x.

PMID:
31406259
[PubMed - as supplied by publisher]
Related citations

Safety of reslizumab in uncontrolled asthma with eosinophilia: a pooled analysis from six trials.
Virchow JC, Katial R, Brusselle G, Shalit Y, Garin M, McDonald M, Castro M
J Allergy Clin Immunol Pract. 2019 Aug 9; pii: S2213-2198(19)30701-9. doi: 10.1016/j.jaip.2019.07.038.

PMID:
31404668
[PubMed - as supplied by publisher]
Related citations

Prenatal and Childhood Traffic-Related Air Pollution Exposure and Telomere Length in European Children: The HELIX Project.
Clemente DBP, Vrijheid M, Martens DS, Bustamante M, Chatzi L, Danileviciute A, de Castro M, Grazuleviciene R, Gutzkow KB, Lepeule J, Maitre L, McEachan RRC, Robinson O, Schwarze PE, Tamayo I, Vafeiadi M, Wright J, Slama R, Nieuwenhuijsen M, Nawrot TS
Environ Health Perspect. 2019 Aug; 127(8)87001. doi: 10.1289/EHP4148.

PMID:
31393792
[PubMed - in process]
Related citations

Automated typing of red blood cell and platelet antigens from whole exome sequences.
Lane WJ, Vege S, Mah HH, Lomas-Francis C, Aguad M, Smeland-Wagman R, Koch C, Killian JM, Gardner CL, De Castro M, Lebo MS, Kaufman RM, Green RC, Westhoff CM, MilSeq Project.
Transfusion. 2019 Aug 8; doi: 10.1111/trf.15473.

PMID:
31392742
[PubMed - as supplied by publisher]
Related citations

Early determinants of linear growth and weight attained in the first year of life in a malaria endemic region.
Dal Bom JP, Mazzucchetti L, Malta MB, Ladeia-Andrade S, de Castro MC, Cardoso MA, Lourenço BH, MINA-Brazil Study Working Group.
PLoS One. 2019; 14(8)e0220513. doi: 10.1371/journal.pone.0220513.

PMID:
31386682
[PubMed - in process]
Related citations

Chemokines: Key Molecules that Orchestrate Communication among Neurons, Microglia and Astrocytes to Preserve Brain Function.
Trettel F, Di Castro MA, Limatola C
Neuroscience. 2019 Jul 31; pii: S0306-4522(19)30519-6. doi: 10.1016/j.neuroscience.2019.07.035.

PMID:
31376422
[PubMed - as supplied by publisher]
Related citations

Elbow Flexion Assist Orthosis for Arthrogryposis.
Wee J, Shank TM, Castro MN, Ryan LE, Costa J, Rahman T
IEEE Int Conf Rehabil Robot. 2019 Jun; 2019494-498. doi: 10.1109/ICORR.2019.8779399.

PMID:
31374678
[PubMed - in process]
Related citations

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians and health professionals are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians and health professionals work collaboratively with pharmaceutical, medical device or other medical care related companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our physicians and health professionals have an ownership or potential ownership interest in a commercial company; and/or are paid by a commercial company to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians or health professionals must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this website, physicians and health professionals earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following financial interests during calendar year 2018:

Company Name: Astrazenica

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $150,000 - $199,999

Reporting Date: May 01, 2019

Company Name: Genetech

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $20,000 - $39,999

Reporting Date: May 01, 2019

Company Name: Teva

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $100,000 - $149,999

Reporting Date: May 01, 2019

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