Patient Portal

Mario Castro, MD, MPH, FCCP

Professor, Medicine and Pediatrics
Division of Pulmonary and Critical Care Medicine

Specialty Areas

Pulmonary Disease
Asthma
Lung Cancer

Board Certifications

Pulmonary Disease
Internal Medicine
Critical Care Medicine

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital

Areas of Clinical Interest

Asthma and related allergic disease, COPD, emphysema, chronic bronchitis, interstital lung disease, idiopathic pulmonary fibrosis, sarcoidosis, chronic cough, unexplained shortness of breath, vasculitis, chronic lung infections, pulmonary hypertension, bronchiectasis.

  • Maps & Directions
  • Education
  • Publication & Research
  • Financial Disclosures

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-454-8917

Education

Education

Graduate: Public Health, St. Louis University School of Public Health, St. Louis, Missouri 1998
Fellowship: Pulmonary/Critical Care, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1994
Residency: Internal Medicine, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1991
Medical Degree: University Of Missouri, Kansas City, Missouri 1988

Publication & Research

Publication & Research

Matrix metalloproteinase (MMP)-2 activation by oxidative stress decreases aortic calponin-1 levels during hypertrophic remodeling in early hypertension.
Blascke de Mello MM, Parente JM, Schulz R, Castro MM
Vascul Pharmacol. 2018 Oct 16; pii: S1537-1891(18)30152-6. doi: 10.1016/j.vph.2018.10.002.

PMID:
    30339939
    [PubMed - as supplied by publisher]
Related citations


Predicting response to bronchial thermoplasty in patients with severe uncontrolled asthma: An elusive goal.
Hall CS, Castro M
Respirology. 2018 Oct 15; doi: 10.1111/resp.13424.

PMID:
    30324712
    [PubMed - as supplied by publisher]
Related citations


Familial clustering of bicuspid aortic valve and its relationship with aortic dilation in first-degree relatives.
Galian-Gay L, Carro Hevia A, Teixido-Turà G, Rodríguez Palomares J, Gutiérrez-Moreno L, Maldonado G, Gonzàlez-Alujas MT, Sao-Aviles A, Gallego P, Calvo-Iglesias F, Bermejo J, Robledo-Carmona J, Sánchez V, Saura D, Sevilla T, Burillo-Sanz S, Guala A, Garcia-Dorado D, Evangelista A, BICUSPID investigators.
Heart. 2018 Oct 15; pii: heartjnl-2018-313802. doi: 10.1136/heartjnl-2018-313802.

PMID:
    30322846
    [PubMed - as supplied by publisher]
Related citations


Ticks (Acari: Ixodidae) in the Serra da Canastra National Park in Minas Gerais, Brazil: species, abundance, ecological and seasonal aspects with notes on rickettsial infection.
Szabó MPJ, Martins MM, de Castro MB, Pacheco RC, Tolesano-Pascoli GV, Dos Santos KT, Martins TF, de Souza LGA, May-Junior JA, Yokosawa J, Labruna MB
Exp Appl Acarol. 2018 Oct 13; doi: 10.1007/s10493-018-0300-9.

PMID:
    30317459
    [PubMed - as supplied by publisher]
Related citations


Argasid and ixodid systematics: Implications for soft tick evolution and systematics, with a new argasid species list.
Mans BJ, Featherston J, Kvas M, Pillay KA, de Klerk DG, Pienaar R, de Castro MH, Schwan TG, Lopez JE, Teel P, Pérez de León AA, Sonenshine DE, Egekwu NI, Bakkes DK, Heyne H, Kanduma EG, Nyangiwe N, Bouattour A, Latif AA
Ticks Tick Borne Dis. 2018 Oct 1; pii: S1877-959X(18)30154-7. doi: 10.1016/j.ttbdis.2018.09.010.

PMID:
    30309738
    [PubMed - as supplied by publisher]
Related citations


Cortical thickness, brain metabolic activity, and in vivo amyloid deposition in asymptomatic, middle-aged offspring of patients with late-onset Alzheimer's disease.
Duarte-Abritta B, Villarreal MF, Abulafia C, Loewenstein D, Curiel Cid RE, Castro MN, Surace E, Sánchez SM, Vigo DE, Vázquez S, Nemeroff CB, Sevlever G, Guinjoan SM
J Psychiatr Res. 2018 Oct 5; 10711-18. doi: 10.1016/j.jpsychires.2018.10.008.

PMID:
    30308328
    [PubMed - as supplied by publisher]
Related citations


First passage events in biological systems with non-exponential inter-event times.
Castro M, López-García M, Lythe G, Molina-París C
Sci Rep. 2018 Oct 10; 8(1)15054. doi: 10.1038/s41598-018-32961-7.

PMID:
    30305644
    [PubMed - in process]
Related citations


Brain Structural and Amyloid Correlates of Recovery From Semantic Interference in Cognitively Normal Individuals With or Without Family History of Late-Onset Alzheimer's Disease.
Abulafia C, Loewenstein D, Curiel-Cid R, Duarte-Abritta B, Sánchez SM, Vigo DE, Castro MN, Drucaroff LJ, Vázquez S, Sevlever G, Nemeroff CB, Guinjoan SM, Villarreal MF
J Neuropsychiatry Clin Neurosci. 2018 Oct 11; appineuropsych17120355. doi: 10.1176/appi.neuropsych.17120355.

PMID:
    30305005
    [PubMed - as supplied by publisher]
Related citations


Adaptation of the Nursing Activities Score for oncologic care.
Silva TCMDSE, Castro MCN, Popim RC
Rev Bras Enferm. 2018 Sep-Oct; 71(5)2383-2391. doi: 10.1590/0034-7167-2017-0015.

PMID:
    30304166
    [PubMed - in process]
Related citations


Proteome analysis of Phytomonas serpens, a phytoparasite of medical interest.
Dos Santos Júnior ACM, Ricart CAO, Pontes AH, Fontes W, Souza AR, Castro MS, de Sousa MV, de Lima BD
PLoS One. 2018; 13(10)e0204818. doi: 10.1371/journal.pone.0204818.

PMID:
    30303999
    [PubMed - in process]
Related citations


Accuracy of the Narrow-band Imaging International Colorectal Endoscopic Classification System in Identification of Deep Invasion in Colorectal Polyps.
Puig I, López-Cerón M, Arnau A, Rosiñol Ò, Cuatrecasas M, Herreros-de-Tejada A, Ferrández Á, Serra-Burriel M, Nogales Ó, Vida F, de Castro L, López-Vicente J, Vega P, Álvarez-González MA, González-Santiago J, Hernández-Conde M, Díez-Redondo P, Sánchez LR, Gimeno-García AZ, Burgos A, García-Alonso FJ, Bustamante-Balén M, Martínez-Bauer E, Peñas B, Pellise M, EndoCAR group, Spanish Gastroenterological Association and the Spanish Digestive Endoscopy Society. Collaborators.
Gastroenterology. 2018 Oct 5; pii: S0016-5085(18)35094-7. doi: 10.1053/j.gastro.2018.10.004.

PMID:
    30296432
    [PubMed - as supplied by publisher]
Related citations


Phenolic Imidazole Derivatives with Dual Antioxidant/Antifungal Activity: Synthesis and Structure-Activity Relationship.
Bettencourt AP, Castro M, Silva JP, Fernandes F, Coutinho OP, Sousa MJ, Proenca MF, Areias FM
Med Chem. 2018 Oct 5; doi: 10.2174/1573406414666181005143431.

PMID:
    30295192
    [PubMed - as supplied by publisher]
Related citations


Acylation of the S4<sub>13</sub>-PV cell-penetrating peptide as a means of enhancing its capacity to mediate nucleic acid delivery: Relevance of peptide/lipid interactions.
Morais CM, Cardoso AM, Cunha PP, Aguiar L, Vale N, Lage E, Pinheiro M, Nunes C, Gomes P, Reis S, Castro MMCA, Pedroso de Lima MC, Jurado AS
Biochim Biophys Acta Biomembr. 2018 Oct 4; 1860(12)2619-2634. doi: 10.1016/j.bbamem.2018.10.002.

PMID:
    30291923
    [PubMed - as supplied by publisher]
Related citations


Surfaces Patterned by Ion Sputtering.
Munoz-Garcia J, Cuerno R, Castro M, Vazquez Burgos L, Gago R, Redondo-Cubero A
J Phys Condens Matter. 2018 Oct 4; doi: 10.1088/1361-648X/aae608.

PMID:
    30284539
    [PubMed - as supplied by publisher]
Related citations


New Nitrogen Compounds Coupled to Phenolic Units with Antioxidant and Antifungal Activities: Synthesis and Structure⁻Activity Relationship.
Bettencourt A, Castro M, Silva J, Fernandes F, Coutinho O, Sousa MJ, Proença MF, Areias F
Molecules. 2018 Oct 3; 23(10)pii: E2530. doi: 10.3390/molecules23102530.

PMID:
    30282927
    [PubMed - in process]
Related citations


Pit viper envenomation in a barn cat.
Machado M, Wilson TM, Sousa DER, Martins CS, Castro MB
J Small Anim Pract. 2018 Oct 1; doi: 10.1111/jsap.12922.

PMID:
    30276814
    [PubMed - as supplied by publisher]
Related citations


Blockade of Na/H exchanger stimulates glioma tumor immunogenicity and enhances combinatorial TMZ and anti-PD-1 therapy.
Guan X, Hasan MN, Begum G, Kohanbash G, Carney KE, Pigott VM, Persson AI, Castro MG, Jia W, Sun D
Cell Death Dis. 2018 Sep 27; 9(10)1010. doi: 10.1038/s41419-018-1062-3.

PMID:
    30262908
    [PubMed - in process]
Related citations


Epidemiology of Aspergillus species causing keratitis in Mexico.
Al-Hatmi AMS, Castro MA, de Hoog GS, Badali H, Alvarado VF, Verweij PE, Meis JF, Zago VV
Mycoses. 2018 Sep 26; doi: 10.1111/myc.12855.

PMID:
    30256460
    [PubMed - as supplied by publisher]
Related citations


Predictors of inhaled corticosteroid taper failure in adults with asthma.
Cardet JC, Codispoti CD, King TS, Bacharier L, Carr T, Castro M, Chinchilli V, Dunn R, Holquing F, Engle L, Nelson K, Ortega VE, Peters M, Ramratnam S, Krishnan JA, Wechsler ME, Israel E, National Heart, Lung, and Blood Institute Asthmanet.
J Allergy Clin Immunol Pract. 2018 Sep 19; pii: S2213-2198(18)30581-6. doi: 10.1016/j.jaip.2018.05.039.

PMID:
    30240889
    [PubMed - as supplied by publisher]
Related citations


Xanthohumol inhibits cell proliferation and induces apoptosis in human thyroid cells.
Carvalho DO, Freitas J, Nogueira P, Henriques SN, Carmo AM, Castro MA, Guido LF
Food Chem Toxicol. 2018 Nov; 121450-457. doi: 10.1016/j.fct.2018.09.021.

PMID:
    30240731
    [PubMed - in process]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians and health professionals are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians and health professionals work collaboratively with pharmaceutical, medical device or other medical care related companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our physicians and health professionals have an ownership or potential ownership interest in a commercial company; and/or are paid by a commercial company to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians or health professionals must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this website, physicians and health professionals earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following financial interests during calendar year 2017:

Company Name: Genentech

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $10,000 - $19,999

Reporting Date: May 01, 2018


Company Name: Teva

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $100,000 - $149,999

Reporting Date: May 01, 2018


Company Name: Astrazenica

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $20,000 - $39,999

Reporting Date: May 01, 2018