Patient Portal

Mario Castro, MD, MPH, FCCP

Professor, Medicine and Pediatrics
Division of Pulmonary and Critical Care Medicine

Specialty Areas

Pulmonary Disease
Asthma
Lung Cancer

Board Certifications

Pulmonary Disease
Internal Medicine
Critical Care Medicine

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital

Areas of Clinical Interest

Asthma and related allergic disease, COPD, emphysema, chronic bronchitis, interstital lung disease, idiopathic pulmonary fibrosis, sarcoidosis, chronic cough, unexplained shortness of breath, vasculitis, chronic lung infections, pulmonary hypertension, bronchiectasis.

  • Location(s)
  • Education
  • Publication & Research
  • Financial Disclosures

Location(s)

Location(s)

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-454-8917

Education

Education

Graduate: Public Health, St. Louis University School of Public Health, St. Louis, Missouri 1998
Fellowship: Pulmonary/Critical Care, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1994
Residency: Internal Medicine, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1991
Medical Degree: University Of Missouri, Kansas City, Missouri 1988

Publication & Research

Publication & Research

The effect of BPIFA1/SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelium.
Schaefer N, Li X, Seibold MA, Jarjour NN, Denlinger LC, Castro M, Coverstone AM, Teague WG, Boomer J, Bleecker ER, Meyers DA, Moore WC, Hawkins GA, Fahy J, Phillips BR, Mauger DT, Dakhama A, Gellatly S, Pavelka N, Berman R, Di YP, Wenzel SE, Chu HW
JCI Insight. 2019 Apr 18; 4(8)pii: 127237. doi: 10.1172/jci.insight.127237.

PMID:
    30996135
    [PubMed - in process]
Related citations


EFFECT OF SUBSCAPULARIS TEARS ON FUNCTIONAL SCORES OF PATIENTS UNDERGOING ROTATOR CUFF REPAIR.
Malavolta EA, Chang VYP, de Castro MTBP, Andrade-Silva FB, Assunção JH, Gracitelli MEC, Ferreira AA
Acta Ortop Bras. 2019 Mar-Apr; 27(2)116-119. doi: 10.1590/1413-785220192702214524.

PMID:
    30988659
    [PubMed]
Related citations


Anti-Herpetic, Anti-Dengue and Antineoplastic Activities of Simple and Heterocycle-Fused Derivatives of Terpenyl-1,4-Naphthoquinone and 1,4-Anthraquinone.
Roa-Linares VC, Miranda-Brand Y, Tangarife-Castaño V, Ochoa R, García PA, Castro MÁ, Betancur-Galvis L, San Feliciano A
Molecules. 2019 Apr 2; 24(7)pii: E1279. doi: 10.3390/molecules24071279.

PMID:
    30986933
    [PubMed - in process]
Related citations


Effect of Caveolin-1 upon Stat3-ptyr705 levels in breast and lung carcinoma cells.
Geletu M, Taha Z, Arulanandam R, Mohan R, Assi HH, Castro MG, Nabi IR, Gunning PT, Raptis L PhD
Biochem Cell Biol. 2019 Apr 15; doi: 10.1139/bcb-2018-0367.

PMID:
    30986357
    [PubMed - as supplied by publisher]
Related citations


Effectiveness and safety of the switch from Remicade to CT-P13 in patients with inflammatory bowel disease.
Chaparro M, Garre A, Guerra Veloz MF, Vázquez JM, De Castro ML, Leo E, Rodriguez E, Carbajo AY, Riestra S, Jiménez I, Calvet X, Bujanda L, Rivero M, Gomollón F, Benítez JM, Bermejo F, Alcaide N, Gutiérrez A, Mañosa M, Iborra M, Lorente R, Rojas-Feria M, Barreiro-de Acosta M, Kolle L, Van Domselaar M, Amo V, Argüelles F, Ramírez E, Morell A, Bernardo D, Gisbert JP
J Crohns Colitis. 2019 Apr 12; pii: jjz070. doi: 10.1093/ecco-jcc/jjz070.

PMID:
    30976785
    [PubMed - as supplied by publisher]
Related citations


Bulk Modification of Poly(lactide) (PLA) via Copolymerization with Poly(propylene glycol) Diglycidylether (PPGDGE).
Castillejos S, Cerna J, Meléndez F, Castro ME, Aguilar R, Márquez-Beltrán C, González M
Polymers (Basel). 2018 Oct 24; 10(11)pii: E1184. doi: 10.3390/polym10111184.

PMID:
    30961109
    [PubMed]
Related citations


Gonadotropin-dependent pubertal disorders are common in patients with virilizing adrenocortical tumors in childhood.
Stecchini MF, Braid Z, More CB, Aragon DC, De Castro M, Moreira AC, Antonini SRR
Endocr Connect. 2019 Apr 1; pii: EC-19-0141. doi: 10.1530/EC-19-0141.

PMID:
    30959478
    [PubMed - as supplied by publisher]
Related citations


Phenotypic diversity and glucocorticoid sensitivity in patients with familial partial lipodystrophy type 2.
Resende ATP, Martins CS, Bueno AC, Moreira AC, Foss-Freitas MC, de Castro M
Clin Endocrinol (Oxf). 2019 Apr 6; doi: 10.1111/cen.13984.

PMID:
    30954027
    [PubMed - as supplied by publisher]
Related citations


Sex and Gender Role Differences in Occupational Exposures and Work Outcomes Among Registered Nurses in Correctional Settings.
Ghaziri ME, Dugan AG, Zhang Y, Gore R, Castro ME
Ann Work Expo Health. 2019 Mar 30; pii: wxz018. doi: 10.1093/annweh/wxz018.

PMID:
    30927407
    [PubMed - as supplied by publisher]
Related citations


RTNsurvival : An R/Bioconductor package for regulatory network survival analysis.
Groeneveld CS, Chagas VS, Jones SJM, Robertson AG, Ponder BAJ, Meyer KB, Castro MAA
Bioinformatics. 2019 Mar 28; pii: btz229. doi: 10.1093/bioinformatics/btz229.

PMID:
    30923832
    [PubMed - as supplied by publisher]
Related citations


Immunopathological findings in a cat with auricular chondritis.
Meziara Wilson T, Machado M, De Sousa DER, Braúna T, Torres Neto R, Laufer-Amorim R, Szabó MPJ, De Castro MB
Acta Vet Hung. 2019 Mar; 67(1)81-86. doi: 10.1556/004.2019.009.

PMID:
    30922093
    [PubMed - in process]
Related citations


Cancer-associated thrombosis: the when, how and why.
Fernandes CJ, Morinaga LTK, Alves JL  Jr, Castro MA, Calderaro D, Jardim CVP, Souza R
Eur Respir Rev. 2019 Mar 31; 28(151)pii: 180119. doi: 10.1183/16000617.0119-2018.

PMID:
    30918022
    [PubMed - in process]
Related citations


Effects of Albumin Treatment on Systemic and Portal Hemodynamics and Systemic Inflammation in Patients With Decompensated Cirrhosis.
Fernández J, Clària J, Amorós A, Aguilar F, Castro M, Casulleras M, Acevedo J, Duran-Güell M, Nuñez L, Costa M, Torres M, Horrillo R, Ruiz-Del-Árbol L, Villanueva C, Prado V, Arteaga M, Trebicka J, Angeli P, Merli M, Alessandria C, Aagaard NK, Soriano G, Durand F, Gerbes A, Gustot T, Welzel TM, Salerno F, Bañares R, Vargas V, Albillos A, Silva A, Morales-Ruiz M, Pavesi M, Jalan R, Bernardi M, Moreau R, Páez A, Arroyo V
Gastroenterology. 2019 Mar 21; pii: S0016-5085(19)33576-0. doi: 10.1053/j.gastro.2019.03.021.

PMID:
    30905652
    [PubMed - as supplied by publisher]
Related citations


More than myelin: Probing white matter differences in prematurity with quantitative T1 and diffusion MRI.
Travis KE, Castro MRH, Berman S, Dodson CK, Mezer AA, Ben-Shachar M, Feldman HM
Neuroimage Clin. 2019 Mar 12; 22101756. doi: 10.1016/j.nicl.2019.101756.

PMID:
    30901711
    [PubMed - as supplied by publisher]
Related citations


Nucleotide Second Messenger-Based Signaling in Extreme Acidophiles of the <i>Acidithiobacillus</i> Species Complex: Partition Between the Core and Variable Gene Complements.
Moya-Beltrán A, Rojas-Villalobos C, Díaz M, Guiliani N, Quatrini R, Castro M
Front Microbiol. 2019; 10381. doi: 10.3389/fmicb.2019.00381.

PMID:
    30899248
    [PubMed]
Related citations


Multiple Sulfatase Deficiency
Schlotawa L, Adang L, De Castro M, Ahrens-Nicklas R, Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A
. 1993;

PMID:
    30896912
    [PubMed]
Related citations


The vexing complexity of the amyloidogenic pathway.
Castro MA, Hadziselimovic A, Sanders CR
Protein Sci. 2019 Mar 21; doi: 10.1002/pro.3606.

PMID:
    30897251
    [PubMed - as supplied by publisher]
Related citations


[Initial Experience of a TAVI Program: Analysis of the Anesthetic Decision and its Evolution].
Martins A, Castro ML, Fragata I
Acta Med Port. 2019 Feb 28; 32(2)126-132. doi: 10.20344/amp.10982.

PMID:
    30896393
    [PubMed - in process]
Related citations


Fate of a Naive T Cell: A Stochastic Journey.
de la Higuera L, López-García M, Castro M, Abourashchi N, Lythe G, Molina-París C
Front Immunol. 2019; 10194. doi: 10.3389/fimmu.2019.00194.

PMID:
    30894850
    [PubMed - in process]
Related citations


Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma.
Lachowicz-Scroggins ME, Dunican EM, Charbit AR, Raymond W, Looney MR, Peters MC, Gordon ED, Woodruff PG, Lefrançais E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Fajt ML, Wenzel SE, Israel E, D Levy B, Fahy JV, National Heart, Lung, and Blood Institute Severe Asthma Research Program-3 Investigators.
Am J Respir Crit Care Med. 2019 Mar 19; doi: 10.1164/rccm.201810-1869OC.

PMID:
    30888839
    [PubMed - as supplied by publisher]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians and health professionals are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians and health professionals work collaboratively with pharmaceutical, medical device or other medical care related companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our physicians and health professionals have an ownership or potential ownership interest in a commercial company; and/or are paid by a commercial company to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians or health professionals must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this website, physicians and health professionals earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following financial interests during calendar year 2017:

Company Name: Genentech

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $10,000 - $19,999

Reporting Date: May 01, 2018


Company Name: Teva

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $100,000 - $149,999

Reporting Date: May 01, 2018


Company Name: Astrazenica

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $20,000 - $39,999

Reporting Date: May 01, 2018