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Faculty Physicians

Mario Castro, MD, MPH, FCCP

Professor, Medicine and Pediatrics
Division of Pulmonary and Critical Care Medicine

Specialty Areas

Pulmonary Disease
Asthma
Lung Cancer

Board Certifications

Pulmonary Disease
Internal Medicine
Critical Care Medicine

Areas of Clinical Interest

Asthma and related allergic disease, COPD, emphysema, chronic bronchitis, interstital lung disease, idiopathic pulmonary fibrosis, sarcoidosis, chronic cough, unexplained shortness of breath, vasculitis, chronic lung infections, pulmonary hypertension, bronchiectasis.

  • Maps & Directions
  • Education
  • Publication & Research
  • Financial Disclosures

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-454-8917

Education

Education

Graduate: Public Health, St. Louis University School of Public Health, St. Louis, Missouri 1998
Fellowship: Pulmonary/Critical Care, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1994
Residency: Internal Medicine, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1991
Medical Degree: University Of Missouri, Kansas City, Missouri 1988

Publication & Research

Publication & Research

Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: a randomized clinical trial.
Smith LJ, Kalhan R, Wise RA, Sugar EA, Lima JJ, Irvin CG, Dozor AJ, Holbrook JT, American Lung Association Asthma Clinical Research Centers
JAMA. 2015 May 26; 313(20)2033-43. doi: 10.1001/jama.2015.5024.

PMID:
    26010632
    [PubMed - indexed for MEDLINE]
Related citations


Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo.
Bentley-Lewis R, Aguilar D, Riddle MC, Claggett B, Diaz R, Dickstein K, Gerstein HC, Johnston P, Køber LV, Lawson F, Lewis EF, Maggioni AP, McMurray JJ, Ping L, Probstfield JL, Solomon SD, Tardif JC, Wu Y, Pfeffer MA, ELIXA Investigators
Am Heart J. 2015 May; 169(5)631-638.e7. doi: 10.1016/j.ahj.2015.02.002.

PMID:
    25965710
    [PubMed - indexed for MEDLINE]
Related citations


Calcium channel blocker reduces airway remodeling-or does it?
Sumino K, Sheshadri A, Castro M
Am J Respir Crit Care Med. 2015 Apr 15; 191(8)863-4. doi: 10.1164/rccm.201502-0322ED.

PMID:
    25876196
    [PubMed - indexed for MEDLINE]
Related citations


Empirically derived dietary patterns: interpretability and construct validity according to different factor rotation methods.
Castro MA, Baltar VT, Selem SS, Marchioni DM, Fisberg RM
Cad Saude Publica. 2015 Feb; 31(2)298-310.

PMID:
    25760164
    [PubMed - indexed for MEDLINE]
Related citations


Spatial analysis of under-5 mortality and potential risk factors in the Basse Health and Demographic Surveillance System, the Gambia.
Quattrochi J, Jasseh M, Mackenzie G, Castro MC
Trop Med Int Health. 2015 Jul; 20(7)941-51. doi: 10.1111/tmi.12490.

PMID:
    25728631
    [PubMed - indexed for MEDLINE]
Related citations


Sonic Hedgehog pathway is upregulated in adamantinomatous craniopharyngiomas.
Gomes DC, Jamra SA, Leal LF, Colli LM, Campanini ML, Oliveira RS, Martinelli CE Jr, Elias PC, Moreira AC, Machado HR, Saggioro F, Neder L, Castro M, Antonini SR
Eur J Endocrinol. 2015 May; 172(5)603-8. doi: 10.1530/EJE-14-0934.

PMID:
    25693592
    [PubMed - indexed for MEDLINE]
Related citations


Study of the prevalence of Capillaria hepatica in humans and rodents in an urban area of the city of Porto Velho, Rondônia, Brazil.
Rocha EJ, Basano Sde A, Souza MM, Honda ER, Castro MB, Colodel EM, e Silva JC, Barros LP, Rodrigues ES, Camargo LM
Rev Inst Med Trop Sao Paulo. 2015 Jan-Feb; 57(1)39-46. doi: 10.1590/S0036-46652015000100006.

PMID:
    25651325
    [PubMed - indexed for MEDLINE]
Related citations


Safety and accuracy of endovascular aneurysm repair without pre-operative and intra-operative contrast agent.
Kaladji A, Dumenil A, Mahé G, Castro M, Cardon A, Lucas A, Haigron P
Eur J Vasc Endovasc Surg. 2015 Mar; 49(3)255-61. doi: 10.1016/j.ejvs.2014.12.003.

PMID:
    25617257
    [PubMed - indexed for MEDLINE]
Related citations


Agonist-dependent modulation of cell surface expression of the cold receptor TRPM8.
Toro CA, Eger S, Veliz L, Sotelo-Hitschfeld P, Cabezas D, Castro MA, Zimmermann K, Brauchi S
J Neurosci. 2015 Jan 14; 35(2)571-82. doi: 10.1523/JNEUROSCI.3820-13.2015.

PMID:
    25589752
    [PubMed - indexed for MEDLINE]
Related citations


Comprehensive description of clinical characteristics of a large systemic lupus erythematosus cohort from the Spanish Rheumatology Society Lupus Registry (RELESSER) with emphasis on complete versus incomplete lupus differences.
Rúa-Figueroa Í, Richi P, López-Longo FJ, Galindo M, Calvo-Alén J, Olivé-Marqués A, Loza-Santamaría E, Vicente SP, Erausquin C, Tomero E, Horcada L, Uriarte E, Sánchez-Atrio A, Rosas J, Montilla C, Fernández-Nebro A, Rodríguez-Gómez M, Vela P, Blanco R, Freire M, Silva L, Díez-Álvarez E, Ibáñez-Barceló M, Zea A, Narváez J, Martínez-Taboada V, Marenco JL, de Castro MF, Fernández-Berrizbeitia O, Hernández-Beriain JÁ, Gantes M, Hernández-Cruz B, Pérez-Venegas JJ, Pecondón Á, Marras C, Carreira P, Bonilla G, Torrente V, Castellví I, Alegre J, Moreno M, Raya E, de la Peña PG, Vázquez T, Aguirre Á, Quevedo V, Pego-Reigosa JM, EAS-SER (Systemic Diseases Study Group of the Spanish Society of Rheumatology)
Medicine (Baltimore). 2015 Jan; 94(1)e267. doi: 10.1097/MD.0000000000000267.

PMID:
    25569641
    [PubMed - indexed for MEDLINE]
Related citations


Prevalence of somatic mutl homolog 1 promoter hypermethylation in Lynch syndrome colorectal cancer.
Moreira L, Muñoz J, Cuatrecasas M, Quintanilla I, Leoz ML, Carballal S, Ocaña T, López-Cerón M, Pellise M, Castellví-Bel S, Jover R, Andreu M, Carracedo A, Xicola RM, Llor X, Boland CR, Goel A, Castells A, Balaguer F, Gastrointestinal Oncology Group of the Spanish Gastroenterological Association
Cancer. 2015 May 1; 121(9)1395-404. doi: 10.1002/cncr.29190.

PMID:
    25557234
    [PubMed - indexed for MEDLINE]
Related citations


Imaging pulmonary inducible nitric oxide synthase expression with PET.
Huang HJ, Isakow W, Byers DE, Engle JT, Griffin EA, Kemp D, Brody SL, Gropler RJ, Miller JP, Chu W, Zhou D, Pierce RA, Castro M, Mach RH, Chen DL
J Nucl Med. 2015 Jan; 56(1)76-81. doi: 10.2967/jnumed.114.146381.

PMID:
    25525182
    [PubMed - indexed for MEDLINE]
Related citations


Bronchial thermoplasty: ready for prime time--the evidence is there!
Castro M, Cox G, Wechsler ME, Niven RM
Chest. 2015 Feb; 147(2)e73-4. doi: 10.1378/chest.14-2296.

PMID:
    25522284
    [PubMed - indexed for MEDLINE]
Related citations


"Pulmonary valve replacement diminishes the presence of restrictive physiology and reduces atrial volumes": a prospective study in Tetralogy of Fallot patients.
Pijuan-Domenech A, Pineda V, Castro MA, Sureda-Barbosa C, Ribera A, Cruz LM, Ferreira-Gonzalez I, Dos-Subirà L, Subirana-Domènech T, Garcia-Dorado D, Casaldàliga-Ferrer J
Int J Cardiol. 2014 Nov 15; 177(1)261-5. doi: 10.1016/j.ijcard.2014.09.009.

PMID:
    25499390
    [PubMed - indexed for MEDLINE]
Related citations


Randomized trial to evaluate azithromycin's effects on serum and upper airway IL-8 levels and recurrent wheezing in infants with respiratory syncytial virus bronchiolitis.
Beigelman A, Isaacson-Schmid M, Sajol G, Baty J, Rodriguez OM, Leege E, Lyons K, Schweiger TL, Zheng J, Schechtman KB, Castro M, Bacharier LB
J Allergy Clin Immunol. 2015 May; 135(5)1171-8.e1. doi: 10.1016/j.jaci.2014.10.001.

PMID:
    25458910
    [PubMed - indexed for MEDLINE]
Related citations


Influence of wedges on lower limbs' kinematics and net joint moments during healthy elderly gait using principal component analysis.
Soares DP, de Castro MP, Mendes E, Machado L
Hum Mov Sci. 2014 Dec; 38319-30. doi: 10.1016/j.humov.2014.09.007.

PMID:
    25457428
    [PubMed - indexed for MEDLINE]
Related citations


Metabolic alterations, HFE gene mutations and atherogenic lipoprotein modifications in patients with primary iron overload.
Meroño T, Brites F, Dauteuille C, Lhomme M, Menafra M, Arteaga A, Castro M, Saez MS, Ballerga EG, Sorroche P, Rey J, Lesnik P, Sordá JA, Chapman MJ, Kontush A, Daruich J
Clin Sci (Lond). 2015 May; 128(9)609-18. doi: 10.1042/CS20140300.

PMID:
    25442240
    [PubMed - indexed for MEDLINE]
Related citations


sEMG feature evaluation for identification of elbow angle resolution in graded arm movement.
Castro MC, Colombini EL, Aquino PT Jr, Arjunan SP, Kumar DK
Biomed Eng Online. 2014 Nov 25; 13155. doi: 10.1186/1475-925X-13-155.

PMID:
    25422006
    [PubMed - indexed for MEDLINE]
Related citations


Factors affecting providers' delivery of intermittent preventive treatment for malaria in pregnancy: a five-country analysis of national service provision assessment surveys.
Maheu-Giroux M, Castro MC
Malar J. 2014 Nov 20; 13440. doi: 10.1186/1475-2875-13-440.

PMID:
    25409680
    [PubMed - indexed for MEDLINE]
Related citations


Cuban internationalism - an alternative form of globalization.
Castro M, Melluish S, Lorenzo A
Int Rev Psychiatry. 2014 Oct; 26(5)595-601. doi: 10.3109/09540261.2014.920770.

PMID:
    25343637
    [PubMed - indexed for MEDLINE]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2014.

Company Name: Genentech

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $25,001 - $50,000

Reporting Date: May 01, 2015


Company Name: Advanced Health

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $10,001 - $25,000

Reporting Date: May 01, 2015


Company Name: Sparo

Royalties:

Equity: Yes

Consulting/Advisory Board:

Speaker Fees:

Reporting Date: May 01, 2015