Mario Castro, MD, MPH, FCCP

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Mario Castro, MD, MPH, FCCP

Professor, Medicine and Pediatrics
Division of Pulmonary and Critical Care Medicine

Specialty Areas

Pulmonary Disease
Asthma
Lung Cancer

Board Certifications

Pulmonary Disease
Internal Medicine
Critical Care Medicine

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital

Areas of Clinical Interest

Asthma and related allergic disease, COPD, emphysema, chronic bronchitis, interstital lung disease, idiopathic pulmonary fibrosis, sarcoidosis, chronic cough, unexplained shortness of breath, vasculitis, chronic lung infections, pulmonary hypertension, bronchiectasis.

Maps & Directions
Education
Publication & Research
Financial Disclosures

Maps & Directions

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-454-8917

Education

Graduate: Public Health, St. Louis University School of Public Health, St. Louis, Missouri 1998
Fellowship: Pulmonary/Critical Care, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1994
Residency: Internal Medicine, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1991
Medical Degree: University Of Missouri, Kansas City, Missouri 1988

Publication & Research

Combination of heterologous fibrin sealant and bioengineered human embryonic stem cells to improve regeneration following autogenous sciatic nerve grafting repair.
Mozafari R, Kyrylenko S, Castro MV, Ferreira RS Jr, Barraviera B, Oliveira ALR
J Venom Anim Toxins Incl Trop Dis. 2018; 2411. doi: 10.1186/s40409-018-0147-x.

PMID:
29681920
[PubMed]
Related citations

Ethanol withdrawal increases blood pressure and vascular oxidative stress: a role for angiotensin type 1 receptors.
Gonzaga NA, do Vale GT, Parente JM, Yokota R, De Martinis BS, Casarini DE, Castro MM, Tirapelli CR
J Am Soc Hypertens. 2018 Apr 4; pii: S1933-1711(18)30089-5. doi: 10.1016/j.jash.2018.03.012.

PMID:
29680225
[PubMed - as supplied by publisher]
Related citations

Pruning of the Pulmonary Vasculature in Asthma: The SARP Cohort.
Ash SY, Rahaghi FN, Come CE, Ross JC, Colon AG, Cardet-Guisasola JC, Dunican EM, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Mauger DT, Wenzel SE, Levy BD, San Jose Estepar R, Israel E, Washko GR, SARP Investigators.
Am J Respir Crit Care Med. 2018 Apr 19; doi: 10.1164/rccm.201712-2426OC.

PMID:
29672122
[PubMed - as supplied by publisher]
Related citations

New Hybrids Derived from Podophyllic Aldehyde and Diterpenylhydroquinones with Selectivity toward Osteosarcoma Cells.
Hernández ÁP, Díez P, García PA, Miguel Del Corral JM, Pérez-Andrés M, Díez D, San Feliciano A, Fuentes M, Castro MÁ
ACS Med Chem Lett. 2018 Apr 12; 9(4)328-333. doi: 10.1021/acsmedchemlett.7b00493.

PMID:
29670695
[PubMed]
Related citations

The cognitive complexity of concurrent cognitive-motor tasks reveals age-related deficits in motor performance.
Oliveira AS, Reiche MS, Vinescu CI, Thisted SAH, Hedberg C, Castro MN, Jørgensen MG
Sci Rep. 2018 Apr 17; 8(1)6094. doi: 10.1038/s41598-018-24346-7.

PMID:
29666388
[PubMed - in process]
Related citations

Mandibular canal branching assessed with cone beam computed tomography.
de Castro MAA, Barra SG, Vich MOL, Abreu MHG, Mesquita RA
Radiol Med. 2018 Apr 16; doi: 10.1007/s11547-018-0886-3.

PMID:
29663186
[PubMed - as supplied by publisher]
Related citations

MECHANISMS IN ENDOCRINOLOGY: A sense of time of the glucocorticoid circadian clock: from the ontogeny to the diagnosis of Cushing's syndrome.
Moreira AC, Antonini SRR, De Castro M
Eur J Endocrinol. 2018 Apr 16; pii: EJE-18-0102. doi: 10.1530/EJE-18-0102.

PMID:
29661784
[PubMed - as supplied by publisher]
Related citations

Molecular Ablation of Tumor Blood Vessels Inhibits Therapeutic Effects of Radiation and Bevacizumab.
Yadav VN, Altshuler D, Kadiyala P, Zamler D, Comba A, Appelman H, Dunn P, Koschmann C, Castro MG, Löwenstein PR
Neuro Oncol. 2018 Apr 12; doi: 10.1093/neuonc/noy055.

PMID:
29660022
[PubMed - as supplied by publisher]
Related citations

- 174 G>C IL-6 polymorphism and primary iron overload in male patients.
Tetzlaff WF, Meroño T, Botta EE, Martín ME, Sorroche PB, Boero LE, Castro M, Frechtel GD, Rey J, Daruich J, Cerrone GE, Brites F
Ann Hematol. 2018 Apr 14; doi: 10.1007/s00277-018-3333-6.

PMID:
29656314
[PubMed - as supplied by publisher]
Related citations

Two Cases of Disseminated Infection Following Live Organism Anti-Cancer Vaccine Administration in Cancer Patients.
Denham JD, Lee DH, Castro M, Pandya S, Aslam S, Nanjappa S, Greene JN
Int J Infect Dis. 2018 Apr 12; pii: S1201-9712(18)30087-0. doi: 10.1016/j.ijid.2018.04.004.

PMID:
29656135
[PubMed - as supplied by publisher]
Related citations

Potentiation of the humoral immune response elicited by a commercial vaccine against bovine respiratory disease by Enterococcus faecalis CECT7121.
Díaz AM, Almozni B, Molina MA, Sparo MD, Manghi MA, Canellada AM, Castro MS
Benef Microbes. 2018 Apr 10; 1-10. doi: 10.3920/BM2017.0081.

PMID:
29633631
[PubMed - as supplied by publisher]
Related citations

Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma.
DeBoer MD, Phillips BR, Mauger DT, Zein J, Erzurum SC, Fitzpatrick AM, Gaston BM, Myers R, Ross KR, Chmiel J, Lee MJ, Fahy JV, Peters M, Ly NP, Wenzel SE, Fajt ML, Holguin F, Moore WC, Peters SP, Meyers D, Bleecker ER, Castro M, Coverstone AM, Bacharier LB, Jarjour NN, Sorkness RL, Ramratnam S, Irani AM, Israel E, Levy B, Phipatanakul W, Gaffin JM, Gerald Teague W
BMC Pulm Med. 2018 Apr 10; 18(1)58. doi: 10.1186/s12890-018-0612-x.

PMID:
29631584
[PubMed - in process]
Related citations

Selective cytotoxic and genotoxic activities of 5-(2-bromo-5-methoxybenzylidene)-thiazolidine-2,4-dione against NCI-H292 human lung carcinoma cells.
Rodrigues MDD, Santiago PBGS, Marques KMR, Pereira VRA, de Castro MCAB, Cantalice JCLL, da Silva TG, Adam ML, do Nascimento SC, de Albuquerque JFC, Militao GCG
Pharmacol Rep. 2017 Nov 22; 70(3)446-454. doi: 10.1016/j.pharep.2017.11.008.

PMID:
29627691
[PubMed - as supplied by publisher]
Related citations

Impact of the Canonical Wnt Pathway Activation on the Pathogenesis and Prognosis of Adamantinomatous Craniopharyngiomas.
Jucá CEB, Colli LM, Martins CS, Campanini ML, Paixão B, Jucá RV, Saggioro FP, de Oliveira RS, Moreira AC, Machado HR, Neder L, Antonini SR, de Castro M
Horm Metab Res. 2018 Apr 6; doi: 10.1055/a-0593-5956.

PMID:
29625497
[PubMed - as supplied by publisher]
Related citations

Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.
GlobalSurg Collaborative.
Surg Endosc. 2018 Apr 5; doi: 10.1007/s00464-018-6064-9.

PMID:
29623470
[PubMed - as supplied by publisher]
Related citations

Survival of schistosomiasis-associated pulmonary arterial hypertension in the modern management era.
Julio Cesar Fernandes C, Piloto B, Castro M, Gavilanes Oleas F, Leonidas Alves J Jr, Felipe Lopes Prada L, Jardim C, Souza R
Eur Respir J. 2018 Apr 5; pii: 1800307. doi: 10.1183/13993003.00307-2018.

PMID:
29622571
[PubMed - as supplied by publisher]
Related citations

An Online Survey of Hypothyroid Patients Demonstrates Prominent Dissatisfaction.
Peterson SJ, Cappola AR, Castro MR, Dayan CM, Farwell AP, Hennessey JV, Kopp PA, Ross DS, Samuels MH, Sawka AM, Taylor PN, Jonklaas J, Bianco AC
Thyroid. 2018 Apr 5; doi: 10.1089/thy.2017.0681.

PMID:
29620972
[PubMed - as supplied by publisher]
Related citations

Caregiver and pediatric provider perspectives on symptom-based inhaled corticosteroid therapy in asthma.
Dy T, Lewis EM, Murugan V, Gehlert S, Taylor J, Garbutt J, Bacharier LB, Castro M, Sumino K
Respir Med. 2018 Apr; 137201-205. doi: 10.1016/j.rmed.2018.03.001.

PMID:
29605205
[PubMed - in process]
Related citations

Complex cytogeographical patterns reveal a dynamic tetraploid-octoploid contact zone.
Castro M, Castro S, Figueiredo A, Husband B, Loureiro J
AoB Plants. 2018 Mar; 10(2)ply012. doi: 10.1093/aobpla/ply012.

PMID:
29593853
[PubMed]
Related citations

Altered lactate metabolism in Huntington's disease is dependent on GLUT3 expression.
Solís-Maldonado M, Miró MP, Acuña AI, Covarrubias-Pinto A, Loaiza A, Mayorga G, Beltrán FA, Cepeda C, Levine MS, Concha II, Bátiz LF, Carrasco MA, Castro MA
CNS Neurosci Ther. 2018 Apr; 24(4)343-352. doi: 10.1111/cns.12837.

PMID:
29582588
[PubMed - in process]
Related citations

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2016.

Company Name: Genentech

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $25,001 - $50,000

Reporting Date: May 01, 2017

Company Name: Teva

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $50,001 - $100,000

Reporting Date: May 01, 2017

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