Mario Castro, MD, MPH, FCCP

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Mario Castro, MD, MPH, FCCP

Professor, Medicine and Pediatrics
Division of Pulmonary and Critical Care Medicine

Specialty Areas

Pulmonary Disease
Asthma
Lung Cancer

Board Certifications

Pulmonary Disease
Internal Medicine
Critical Care Medicine

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital

Areas of Clinical Interest

Asthma and related allergic disease, COPD, emphysema, chronic bronchitis, interstital lung disease, idiopathic pulmonary fibrosis, sarcoidosis, chronic cough, unexplained shortness of breath, vasculitis, chronic lung infections, pulmonary hypertension, bronchiectasis.

Maps & Directions
Education
Publication & Research
Financial Disclosures

Maps & Directions

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-454-8917

Education

Graduate: Public Health, St. Louis University School of Public Health, St. Louis, Missouri 1998
Fellowship: Pulmonary/Critical Care, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1994
Residency: Internal Medicine, Mayo Clinic, Mayo Graduate School of Medicine, Rochester, Minnesota 1991
Medical Degree: University Of Missouri, Kansas City, Missouri 1988

Publication & Research

Manifesting heterozygotes in McArdle disease: a myth or a reality-role of statins.
Núñez-Manchón J, Ballester-Lopez A, Koehorst E, Linares-Pardo I, Coenen D, Ara I, Rodriguez-Lopez C, Ramos-Fransi A, Martínez-Piñeiro A, Lucente G, Almendrote M, Coll-Cantí J, Pintos-Morell G, Lozano AS, Arenas J, Martín MA, de Castro M, Lucia A, Santalla A, Nogales-Gadea G
J Inherit Metab Dis. 2018 Jun 20; doi: 10.1007/s10545-018-0203-2.

PMID:
29926259
[PubMed - as supplied by publisher]
Related citations

NOD2 Modulates Serotonin Transporter and Interacts with TLR2 and TLR4 in Intestinal Epithelial Cells.
Layunta E, Latorre E, Forcén R, Grasa L, Castro M, Arias MA, Alcalde AI, Mesonero JE
Cell Physiol Biochem. 2018 Jun 15; 47(3)1217-1229. doi: 10.1159/000490218.

PMID:
29913461
[PubMed - as supplied by publisher]
Related citations

ASSOCIATION OF FREE VITAMIN D<sub>3</sub> CONCENTRATIONS AND ASTHMA TREATMENT FAILURES in the VIDA Trial.
Lima JJ, Castro M, King TS, Lang JE, Ortega VE, Peters SP, Denlinger LC, Israel E, Sorkness CA, Wechsler ME, Wenzel SE, Smith LJ
Ann Allergy Asthma Immunol. 2018 Jun 13; pii: S1081-1206(18)30461-7. doi: 10.1016/j.anai.2018.06.001.

PMID:
29908319
[PubMed - as supplied by publisher]
Related citations

Isokinetic hip muscle strength: a systematic review of normative data.
Castro MP, Ruschel C, Santos GM, Ferreira T, Pierri CAA, Roesler H
Sports Biomech. 2018 Jun 13; 1-29. doi: 10.1080/14763141.2018.1464594.

PMID:
29895216
[PubMed - as supplied by publisher]
Related citations

A Late Cretaceous mammal from Brazil and the first radioisotopic age for the Bauru Group.
Castro MC, Goin FJ, Ortiz-Jaureguizar E, Vieytes EC, Tsukui K, Ramezani J, Batezelli A, Marsola JCA, Langer MC
R Soc Open Sci. 2018 May; 5(5)180482. doi: 10.1098/rsos.180482.

PMID:
29892465
[PubMed]
Related citations

Mutant ATRX: uncovering a new therapeutic target for glioma.
Haase S, Garcia-Fabiani MB, Carney S, Altshuler D, Núñez FJ, Méndez FM, Núñez F, Lowenstein PR, Castro MG
Expert Opin Ther Targets. 2018 Jun 20; 1-15. doi: 10.1080/14728222.2018.1487953.

PMID:
29889582
[PubMed - as supplied by publisher]
Related citations

Multi-Task Learning to Identify Outcome-Specific Risk Factors that Distinguish Individual Micro and Macrovascular Complications of Type 2 Diabetes.
Kim E, Pieczkiewicz DS, Castro MR, Caraballo PJ, Simon GJ
AMIA Jt Summits Transl Sci Proc. 2018; 2017122-131.

PMID:
29888055
[PubMed]
Related citations

Bacterial biogeography of adult airways in atopic asthma.
Durack J, Huang YJ, Nariya S, Christian LS, Mark Ansel K, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Rosenberg SR, King TS, White SR, Denlinger LC, Holguin F, Lazarus SC, Lugogo N, Peters SP, Smith LJ, Wechsler ME, Lynch SV, Boushey HA, National Heart, Lung and Blood Institute’s “AsthmaNet”.
Microbiome. 2018 Jun 9; 6(1)104. doi: 10.1186/s40168-018-0487-3.

PMID:
29885665
[PubMed - in process]
Related citations

Dietary Exposure to Tebuconazole Affects Testicular and Epididymal Histomorphometry in Frugivorous Bats.
Machado-Neves M, Neto MJO, Miranda DC, Souza ACF, Castro MM, Sertorio MN, Carvalho TF, Matta SLP, Freitas MB
Bull Environ Contam Toxicol. 2018 Jun 7; doi: 10.1007/s00128-018-2377-6.

PMID:
29881942
[PubMed - as supplied by publisher]
Related citations

Multi-focal sequencing of a diffuse intrinsic pontine glioma establishes PTEN loss as an early event.
Koschmann C, Farooqui Z, Kasaian K, Cao X, Zamler D, Stallard S, Venneti S, Hervey-Jumper S, Garton H, Muraszko K, Franchi L, Robertson PL, Leonard M, Opipari V, Castro MG, Lowenstein PR, Chinnaiyan A, Mody R
NPJ Precis Oncol. 2017; 1(1)32. doi: 10.1038/s41698-017-0033-y.

PMID:
29872713
[PubMed]
Related citations

Estimating Disease Onset Time by Modeling Lab Result Trajectories via Bayes Networks.
Oh W, Yadav P, Kumar V, Caraballo PJ, Castro MR, Steinbach MS, Simon GJ
IEEE Int Conf Healthc Inform. 2017 Aug; 2017374-379. doi: 10.1109/ICHI.2017.41.

PMID:
29862384
[PubMed]
Related citations

Determining the glycation site specificity of human holo-transferrin.
Silva AMN, Coimbra JTS, Castro MM, Oliveira Â, Brás NF, Fernandes PA, Ramos MJ, Rangel M
J Inorg Biochem. 2018 May 26; 18695-102. doi: 10.1016/j.jinorgbio.2018.05.016.

PMID:
29860209
[PubMed - as supplied by publisher]
Related citations

Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations.
Laviña B, Castro M, Niaudet C, Cruys B, Álvarez-Aznar A, Carmeliet P, Bentley K, Brakebusch C, Betsholtz C, Gaengel K
Development. 2018 May 31; pii: dev.161182. doi: 10.1242/dev.161182.

PMID:
29853619
[PubMed - as supplied by publisher]
Related citations

Prominent Levels of the Profibrotic Chemokine CCL18 during Peritonitis: <i>In Vitro</i> Downregulation by Vitamin D Receptor Agonists.
Ossorio M, Martínez V, Bajo MA, Del Peso G, Castro MJ, Romero S, Selgas R, Bellón T
Biomed Res Int. 2018; 20186415892. doi: 10.1155/2018/6415892.

PMID:
29850544
[PubMed - in process]
Related citations

The Kinetics of Anti-HLA Antibodies in the First Year after Kidney Transplantation: In Whom and When Should They Be Monitored?
de Castro MCR, Barbosa EA, Souza RP, Agena F, de Souza PS, Maciel G, Rodrigues H, Panajotopoulos N, David DS, de Paula FJ, David-Neto E
J Transplant. 2018; 20188316860. doi: 10.1155/2018/8316860.

PMID:
29850195
[PubMed]
Related citations

Hemodynamic evaluation of elderly patients during laparoscopic cholecystectomy.
Ramos LPJ, Araújo RB, Castro MDCV, Ramos MRMS, Cunha-E-Silva JA, Iglesias AC
Rev Col Bras Cir. 2018; 45(2)e1659. doi: 10.1590/0100-6991e-20181659.

PMID:
29846461
[PubMed - in process]
Related citations

Implications of Zika virus and congenital Zika syndrome for the number of live births in Brazil.
Castro MC, Han QC, Carvalho LR, Victora CG, França GVA
Proc Natl Acad Sci U S A. 2018 Jun 12; 115(24)6177-6182. doi: 10.1073/pnas.1718476115.

PMID:
29844186
[PubMed - in process]
Related citations

Assessing covariate effects using Jeffreys-type prior in the Cox model in the presence of a monotone partial likelihood.
Wu J, de Castro M, Schifano ED, Chen MH
J Stat Theory Pract. 2018; 12(1)23-41. doi: 10.1080/15598608.2017.1299058.

PMID:
29805335
[PubMed]
Related citations

Photobacterium malacitanum sp. nov., and Photobacterium andalusiense sp. nov., two new bacteria isolated from diseased farmed fish in Southern Spain.
Labella AM, Castro MD, Manchado M, Lucena T, Arahal DR, Borrego JJ
Syst Appl Microbiol. 2018 May 24; pii: S0723-2020(18)30188-7. doi: 10.1016/j.syapm.2018.04.005.

PMID:
29804705
[PubMed - as supplied by publisher]
Related citations

Concurrent segregation and erosion effects in medium-energy iron beam patterning of silicon surfaces.
Redondo-Cubero A, Lorenz K, Palomares FJ, Muñoz A, Castro M, Muñoz-García J, Cuerno R, Vázquez L
J Phys Condens Matter. 2018 Jul 11; 30(27)274001. doi: 10.1088/1361-648X/aac79a.

PMID:
29794326
[PubMed - in process]
Related citations

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians and health professionals are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians and health professionals work collaboratively with pharmaceutical, medical device or other medical care related companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our physicians and health professionals have an ownership or potential ownership interest in a commercial company; and/or are paid by a commercial company to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians or health professionals must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this website, physicians and health professionals earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following financial interests during calendar year 2017:

Company Name: Genentech

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $10,000 - $19,999

Reporting Date: May 01, 2018

Company Name: Teva

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $100,000 - $149,999

Reporting Date: May 01, 2018

Company Name: Astrazenica

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $20,000 - $39,999

Reporting Date: May 01, 2018

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