Patient Portal

Marianna Ruzinova, MD, PhD

Assistant Professor, Pathology & Immunology

Specialty Areas

Pathology
Hematopathology
Liver Pathology

Board Certifications

Anatomic and Clinical Pathology
Hematopathology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Hematologic disorders of peripheral blood, body fluids, bone marrow, lymph nodes, and other tissues.

  • Education
  • Publication & Research

Education

Education

Medical Degree: Weill Cornell Medical College, New York, NY 2005
PhD, Cell Biology and Genetics: Weill Cornell School of Medical Sciences, New York, NY 2004
Fellowship, Hematopathology: Brigham and Women's Hospital, Harvard Medical School, Boston, MA 2010
Residency, Anatomic Pathology and Clinical Pathology: Brigham and Women's Hospital, Harvard Medical School, Boston, MA 2009
BA, Biochemistry: Swarthmore College, Swarthmore, PA 1998

Publication & Research

Publication & Research

Immunophenotypic Variations in Mantle Cell Lymphoma and Their Impact on Clinical Behavior and Outcome.
Aqil B, Triska G, Frater J, Hassan A, Ruzinova MB, Cashen A, Reese Y, Kreisel F
Arch Pathol Lab Med. 2018 Oct; 142(10)1268-1274. doi: 10.5858/arpa.2017-0368-OA.

PMID:
    29869903
    [PubMed - in process]
Related citations


Distinct clinical and magnetic resonance features of metastatic hepatocellular carcinoma treated with pembrolizumab: A case report of late response after pseudoprogression.
Grierson P, Crites D, Ruzinova MB, Yano M, Lim KH
Hepatol Commun. 2018 Feb; 2(2)148-151. doi: 10.1002/hep4.1132.

PMID:
    29404522
    [PubMed]
Related citations


Acute graft-versus-host disease following lung transplantation in a patient with a novel <i>TERT</i> mutation.
Brestoff JR, Vessoni AT, Brenner KA, Uy GL, DiPersio JF, Blinder M, Witt CA, Byers DE, Hachem RR, Truclock EP, Early DS, Anadkat MJ, Musiek A, Javidan-Nejad C, Balfe DM, Rosman IS, Liu C, Zhang L, Despotis GJ, Ruzinova MB, Sehn JK, Amarillo I, Heusel JW, Swat W, Kim BS, Wartman LD, Yusen RD, Batista LFZ
Thorax. 2018 May; 73(5)489-492. doi: 10.1136/thoraxjnl-2017-211121.

PMID:
    29382801
    [PubMed - in process]
Related citations


Tumor-Stroma IL1β-IRAK4 Feedforward Circuitry Drives Tumor Fibrosis, Chemoresistance, and Poor Prognosis in Pancreatic Cancer.
Zhang D, Li L, Jiang H, Li Q, Wang-Gillam A, Yu J, Head R, Liu J, Ruzinova MB, Lim KH
Cancer Res. 2018 Apr 1; 78(7)1700-1712. doi: 10.1158/0008-5472.CAN-17-1366.

PMID:
    29363544
    [PubMed - in process]
Related citations


Utility of a multidisciplinary tumor board in the management of pancreatic and upper gastrointestinal diseases: an observational study.
Brauer DG, Strand MS, Sanford DE, Kushnir VM, Lim KH, Mullady DK, Tan BR Jr, Wang-Gillam A, Morton AE, Ruzinova MB, Parikh PJ, Narra VR, Fowler KJ, Doyle MB, Chapman WC, Strasberg SS, Hawkins WG, Fields RC
HPB (Oxford). 2017 Feb; 19(2)133-139. doi: 10.1016/j.hpb.2016.11.002.

PMID:
    27916436
    [PubMed - indexed for MEDLINE]
Related citations


Constitutive IRAK4 Activation Underlies Poor Prognosis and Chemoresistance in Pancreatic Ductal Adenocarcinoma.
Zhang D, Li L, Jiang H, Knolhoff BL, Lockhart AC, Wang-Gillam A, DeNardo DG, Ruzinova MB, Lim KH
Clin Cancer Res. 2017 Apr 1; 23(7)1748-1759. doi: 10.1158/1078-0432.CCR-16-1121.

PMID:
    27702822
    [PubMed - indexed for MEDLINE]
Related citations


High frequency of KRAS mutation in early onset colorectal adenocarcinoma: implications for pathogenesis.
Watson R, Liu TC, Ruzinova MB
Hum Pathol. 2016 Oct; 56163-70. doi: 10.1016/j.humpath.2016.06.010.

PMID:
    27346571
    [PubMed - indexed for MEDLINE]
Related citations


NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence.
Manda KR, Tripathi P, Hsi AC, Ning J, Ruzinova MB, Liapis H, Bailey M, Zhang H, Maher CA, Humphrey PA, Andriole GL, Ding L, You Z, Chen F
Oncogene. 2016 Jun 23; 35(25)3282-92. doi: 10.1038/onc.2015.389.

PMID:
    26477312
    [PubMed - indexed for MEDLINE]
Related citations


Perioperative Therapy for Surgically Resectable Pancreatic Adenocarcinoma.
Du L, DeFoe M, Ruzinova MB, Olsen JR, Wang-Gillam A
Hematol Oncol Clin North Am. 2015 Aug; 29(4)717-26. doi: 10.1016/j.hoc.2015.04.011.

PMID:
    26226906
    [PubMed - indexed for MEDLINE]
Related citations


Ciliated hepatic foregut cyst: a report of 6 cases and a review of the English literature.
Bishop KC, Perrino CM, Ruzinova MB, Brunt EM
Diagn Pathol. 2015 Jun 30; 1081. doi: 10.1186/s13000-015-0321-1.

PMID:
    26122082
    [PubMed - indexed for MEDLINE]
Related citations


Eosinophilic myocarditis in hypereosinophilic syndrome.
Roehrl MH, Alexander MP, Hammond SB, Ruzinova M, Wang JY, O'Hara CJ
Am J Hematol. 2011 Jul; 86(7)607-8. doi: 10.1002/ajh.21943.

PMID:
    21681785
    [PubMed - indexed for MEDLINE]
Related citations


Altered subcellular localization of c-Myc protein identifies aggressive B-cell lymphomas harboring a c-MYC translocation.
Ruzinova MB, Caron T, Rodig SJ
Am J Surg Pathol. 2010 Jun; 34(6)882-91. doi: 10.1097/PAS.0b013e3181db83af.

PMID:
    20442643
    [PubMed - indexed for MEDLINE]
Related citations


Extranodal natural killer cell/t-cell lymphoma, nasal type, presenting as cutaneous nodules and a small-bowel perforation.
Agarwal P, Ruzinova MB, Harris MH, Qureshi AA, Stebbins WG
Am J Dermatopathol. 2010 Feb; 32(1)83-5. doi: 10.1097/DAD.0b013e3181b15cd4.

PMID:
    19940752
    [PubMed - indexed for MEDLINE]
Related citations


Induction of complete regressions of oncogene-induced breast tumors in mice.
Benezra R, Henke E, Ciarrocchi A, Ruzinova M, Solit D, Rosen N, Nolan D, Mittal V, de Candia P
Cold Spring Harb Symp Quant Biol. 2005; 70375-81.

PMID:
    16869774
    [PubMed - indexed for MEDLINE]
Related citations


Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors.
Ruzinova MB, Schoer RA, Gerald W, Egan JE, Pandolfi PP, Rafii S, Manova K, Mittal V, Benezra R
Cancer Cell. 2003 Oct; 4(4)277-89.

PMID:
    14585355
    [PubMed - indexed for MEDLINE]
Related citations


Id proteins in development, cell cycle and cancer.
Ruzinova MB, Benezra R
Trends Cell Biol. 2003 Aug; 13(8)410-8.

PMID:
    12888293
    [PubMed - indexed for MEDLINE]
Related citations


A genetic approach to understanding tumor angiogenesis.
Benezra R, de Candia P, Li H, Romero E, Lyden D, Rafii S, Ruzinova M
Cold Spring Harb Symp Quant Biol. 2002; 67249-54.

PMID:
    12858547
    [PubMed - indexed for MEDLINE]
Related citations