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Faculty Physicians

Lynn Anne Cornelius, MD

Winfred A. and Emma R. Showman Professor in Dermatology, Medicine
Chief, Division of Dermatology

Specialty Areas

Melanoma
Skin Cancer
Dermatology

Board Certifications

Dermatology

Areas of Clinical Interest

General dermatology, melanoma, mole mapping, skin cancer

  • Education
  • Publication & Research

Education

Education

Fellowship: Immunodermatology, Emory University, Atlanta, Georgia 1992
Residency: Dermatology, Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, Missouri 1989
Medical Degree: University Of Missouri, Columbia, Missouri 1984
B.S.: University of Delaware, Newark, Delaware 1977

Publication & Research

Publication & Research

Histopathologic characteristics of therapy-associated cutaneous neoplasms with vemurafenib, a selective BRAF kinase inhibitor, used in the treatment of melanoma.
Sufficool KE, Hepper DM, Linette GP, Hurst EA, Lu D, Lind AC, Cornelius LA
J Cutan Pathol. 2014 Jul; 41(7)568-75. doi: 10.1111/cup.12346.

PMID:
    24641301
    [PubMed - indexed for MEDLINE]
Related citations


Chronic mTOR activation promotes cell survival in Merkel cell carcinoma.
Lin Z, McDermott A, Shao L, Kannan A, Morgan M, Stack BC Jr, Moreno M, Davis DA, Cornelius LA, Gao L
Cancer Lett. 2014 Mar 28; 344(2)272-81. doi: 10.1016/j.canlet.2013.11.005.

PMID:
    24262658
    [PubMed - indexed for MEDLINE]
Related citations


Chronic itch development in sensory neurons requires BRAF signaling pathways.
Zhao ZQ, Huo FQ, Jeffry J, Hampton L, Demehri S, Kim S, Liu XY, Barry DM, Wan L, Liu ZC, Li H, Turkoz A, Ma K, Cornelius LA, Kopan R, Battey JF Jr, Zhong J, Chen ZF
J Clin Invest. 2013 Nov; 123(11)4769-80.

PMID:
    24216512
    [PubMed - indexed for MEDLINE]
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IL-12p70-producing patient DC vaccine elicits Tc1-polarized immunity.
Carreno BM, Becker-Hapak M, Huang A, Chan M, Alyasiry A, Lie WR, Aft RL, Cornelius LA, Trinkaus KM, Linette GP
J Clin Invest. 2013 Aug; 123(8)3383-94. doi: 10.1172/JCI68395.

PMID:
    23867552
    [PubMed - indexed for MEDLINE]
Related citations


Practices of unregulated tanning facilities in Missouri: implications for statewide legislation.
Balaraman B, Biesbroeck LK, Lickerman SH, Cornelius LA, Jeffe DB
Pediatrics. 2013 Mar; 131(3)415-22. doi: 10.1542/peds.2012-1781.

PMID:
    23439910
    [PubMed - indexed for MEDLINE]
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Preparing the next generation in academic medicine: recruiting and retaining the best.
de Guzman Strong C, Cornelius LA
J Invest Dermatol. 2012 Mar; 132(3 Pt 2)1018-25. doi: 10.1038/jid.2011.407.

PMID:
    22330268
    [PubMed - indexed for MEDLINE]
Related citations


Inhibitory effects of Rap1GAP overexpression on proliferation and migration of endothelial cells via ERK and Akt pathways.
Li W, Jin B, Cornelius LA, Zhou B, Fu X, Shang D, Zheng H
J Huazhong Univ Sci Technolog Med Sci. 2011 Dec; 31(6)721-7. doi: 10.1007/s11596-011-0667-x.

PMID:
    22173489
    [PubMed - indexed for MEDLINE]
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Cancer and itch.
Chiang HC, Huang V, Cornelius LA
Semin Cutan Med Surg. 2011 Jun; 30(2)107-12. doi: 10.1016/j.sder.2011.05.003.

PMID:
    21767772
    [PubMed - indexed for MEDLINE]
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In vivo functional photoacoustic microscopy of cutaneous microvasculature in human skin.
Favazza CP, Cornelius LA, Wang LV
J Biomed Opt. 2011 Feb; 16(2)026004. doi: 10.1117/1.3536522.

PMID:
    21361688
    [PubMed - indexed for MEDLINE]
Related citations


In vivo photoacoustic microscopy of human cutaneous microvasculature and a nevus.
Favazza CP, Jassim O, Cornelius LA, Wang LV
J Biomed Opt. 2011 Jan-Feb; 16(1)016015. doi: 10.1117/1.3528661.

PMID:
    21280921
    [PubMed - indexed for MEDLINE]
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Morphologic features and natural history of scalp nevi in children.
Gupta M, Berk DR, Gray C, Cornelius LA, Bayliss SJ
Arch Dermatol. 2010 May; 146(5)506-11. doi: 10.1001/archdermatol.2010.88.

PMID:
    20479298
    [PubMed - indexed for MEDLINE]
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Contribution of genetic factors for melanoma susceptibility in sporadic US melanoma patients.
Council ML, Gardner JM, Helms C, Liu Y, Cornelius LA, Bowcock AM
Exp Dermatol. 2009 May; 18(5)485-7. doi: 10.1111/j.1600-0625.2008.00807.x.

PMID:
    19320745
    [PubMed - indexed for MEDLINE]
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Discovery of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a selective and orally efficacious inhibitor of the Met kinase superfamily.
Schroeder GM, An Y, Cai ZW, Chen XT, Clark C, Cornelius LA, Dai J, Gullo-Brown J, Gupta A, Henley B, Hunt JT, Jeyaseelan R, Kamath A, Kim K, Lippy J, Lombardo LJ, Manne V, Oppenheimer S, Sack JS, Schmidt RJ, Shen G, Stefanski K, Tokarski JS, Trainor GL, Wautlet BS, Wei D, Williams DK, Zhang Y, Zhang Y, Fargnoli J, Borzilleri RM
J Med Chem. 2009 Mar 12; 52(5)1251-4. doi: 10.1021/jm801586s.

PMID:
    19260711
    [PubMed - indexed for MEDLINE]
Related citations


Down-regulation of Rap1GAP via promoter hypermethylation promotes melanoma cell proliferation, survival, and migration.
Zheng H, Gao L, Feng Y, Yuan L, Zhao H, Cornelius LA
Cancer Res. 2009 Jan 15; 69(2)449-57. doi: 10.1158/0008-5472.CAN-08-2399.

PMID:
    19147557
    [PubMed - indexed for MEDLINE]
Related citations


Discovery of orally active pyrrolopyridine- and aminopyridine-based Met kinase inhibitors.
Cai ZW, Wei D, Schroeder GM, Cornelius LA, Kim K, Chen XT, Schmidt RJ, Williams DK, Tokarski JS, An Y, Sack JS, Manne V, Kamath A, Zhang Y, Marathe P, Hunt JT, Lombardo LJ, Fargnoli J, Borzilleri RM
Bioorg Med Chem Lett. 2008 Jun 1; 18(11)3224-9. doi: 10.1016/j.bmcl.2008.04.047.

PMID:
    18479916
    [PubMed - indexed for MEDLINE]
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Ras-associated protein-1 regulates extracellular signal-regulated kinase activation and migration in melanoma cells: two processes important to melanoma tumorigenesis and metastasis.
Gao L, Feng Y, Bowers R, Becker-Hapak M, Gardner J, Council L, Linette G, Zhao H, Cornelius LA
Cancer Res. 2006 Aug 15; 66(16)7880-8.

PMID:
    16912161
    [PubMed - indexed for MEDLINE]
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Synthesis and SAR of pyrrolotriazine-4-one based Eg5 inhibitors.
Kim KS, Lu S, Cornelius LA, Lombardo LJ, Borzilleri RM, Schroeder GM, Sheng C, Rovnyak G, Crews D, Schmidt RJ, Williams DK, Bhide RS, Traeger SC, McDonnell PA, Mueller L, Sheriff S, Newitt JA, Pudzianowski AT, Yang Z, Wild R, Lee FY, Batorsky R, Ryder JS, Ortega-Nanos M, Shen H, Gottardis M, Roussell DL
Bioorg Med Chem Lett. 2006 Aug 1; 16(15)3937-42.

PMID:
    16730979
    [PubMed - indexed for MEDLINE]
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Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.
Lombardo LJ, Lee FY, Chen P, Norris D, Barrish JC, Behnia K, Castaneda S, Cornelius LA, Das J, Doweyko AM, Fairchild C, Hunt JT, Inigo I, Johnston K, Kamath A, Kan D, Klei H, Marathe P, Pang S, Peterson R, Pitt S, Schieven GL, Schmidt RJ, Tokarski J, Wen ML, Wityak J, Borzilleri RM
J Med Chem. 2004 Dec 30; 47(27)6658-61.

PMID:
    15615512
    [PubMed - indexed for MEDLINE]
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Inflammatory skin diseases of the head and neck.
Rothschild YH, Cornelius LA
Facial Plast Surg Clin North Am. 2003 May; 11(2)131-9.

PMID:
    15062269
    [PubMed - indexed for MEDLINE]
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Ocular melanoma: a review and the relationship to cutaneous melanoma.
Hurst EA, Harbour JW, Cornelius LA
Arch Dermatol. 2003 Aug; 139(8)1067-73.

PMID:
    12925397
    [PubMed - indexed for MEDLINE]
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