Patient Portal

Lorena Buffa, MD

Instructor, Clinical Pediatrics
Washington University Clinical Associates - Cloverleaf Pediatrics

Specialty Areas

Pediatrics
Primary Care

Board Certifications

Pediatrics

Hospital Affiliations

Barnes-Jewish St. Peters Hospital
Progress West Hospital
Barnes-Jewish Hospital
St. Louis Children's Hospital

Languages

Spanish

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Cloverleaf Pediatrics (WUCA)

4200 N. Cloverleaf Drive
St. Peters, MO 63376

Office Phone: (636) 939-3362
Fax: (636) 939-3687

Education

Education

Residency, Pediatrics: Cardinal Glennon Children's Medical Center, St. Louis, MO 2001
Medical Degree: University of Missouri-Columbia, School of Medicine, Columbia, MO 1998
BA, Chemistry: University of Missouri - St. Louis, St. Louis, MO 1993

Publication & Research

Publication & Research

Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor.
Menichincheri M, Ardini E, Magnaghi P, Avanzi N, Banfi P, Bossi R, Buffa L, Canevari G, Ceriani L, Colombo M, Corti L, Donati D, Fasolini M, Felder E, Fiorelli C, Fiorentini F, Galvani A, Isacchi A, Borgia AL, Marchionni C, Nesi M, Orrenius C, Panzeri A, Pesenti E, Rusconi L, Saccardo MB, Vanotti E, Perrone E, Orsini P
J Med Chem. 2016 Apr 14; 59(7)3392-408. doi: 10.1021/acs.jmedchem.6b00064.

PMID:
    27003761
    [PubMed - indexed for MEDLINE]
Related citations


Molecular mechanism of WW-domain binding protein-2 coactivation function in estrogen receptor signaling.
Buffa L, Saeed AM, Nawaz Z
IUBMB Life. 2013 Jan; 65(1)76-84. doi: 10.1002/iub.1105.

PMID:
    23233354
    [PubMed - indexed for MEDLINE]
Related citations


Biophysical basis of the binding of WWOX tumor suppressor to WBP1 and WBP2 adaptors.
McDonald CB, Buffa L, Bar-Mag T, Salah Z, Bhat V, Mikles DC, Deegan BJ, Seldeen KL, Malhotra A, Sudol M, Aqeilan RI, Nawaz Z, Farooq A
J Mol Biol. 2012 Sep 7; 422(1)58-74. doi: 10.1016/j.jmb.2012.05.015.

PMID:
    22634283
    [PubMed - indexed for MEDLINE]
Related citations


Biophysical analysis of binding of WW domains of the YAP2 transcriptional regulator to PPXY motifs within WBP1 and WBP2 adaptors.
McDonald CB, McIntosh SK, Mikles DC, Bhat V, Deegan BJ, Seldeen KL, Saeed AM, Buffa L, Sudol M, Nawaz Z, Farooq A
Biochemistry. 2011 Nov 8; 50(44)9616-27. doi: 10.1021/bi201286p.

PMID:
    21981024
    [PubMed - indexed for MEDLINE]
Related citations


Left atrial remodeling and response to valsartan in the prevention of recurrent atrial fibrillation: the GISSI-AF echocardiographic substudy.
Staszewsky L, Wong M, Masson S, Raimondi E, Gramenzi S, Proietti G, Bicego D, Emanuelli C, Pulitanò G, Taddei F, Nicolis EB, Correale E, Fabbri G, Bertocchi F, Franzosi MG, Maggioni AP, Tognoni G, Disertori M, Latini R, GISSI-AF Investigators.
Circ Cardiovasc Imaging. 2011 Nov; 4(6)721-8. doi: 10.1161/CIRCIMAGING.111.965954.

PMID:
    21926261
    [PubMed - indexed for MEDLINE]
Related citations


Predicting atrial fibrillation recurrence with circulating inflammatory markers in patients in sinus rhythm at high risk for atrial fibrillation: data from the GISSI atrial fibrillation trial.
Masson S, Aleksova A, Favero C, Staszewsky L, Bernardinangeli M, Belvito C, Cioffi G, Sinagra G, Mazzone C, Bertocchi F, Vago T, Peri G, Cuccovillo I, Masuda N, Barlera S, Mantovani A, Maggioni AP, Franzosi MG, Disertori M, Latini R, GISSI-AF investigators.
Heart. 2010 Dec; 96(23)1909-14. doi: 10.1136/hrt.2009.191460.

PMID:
    20965978
    [PubMed - indexed for MEDLINE]
Related citations


3,4,5-Trisubstituted-1,2,4-4H-triazoles as WT and Y188L mutant HIV-1 non-nucleoside reverse transcriptase inhibitors: docking-based CoMFA and CoMSIA analyses.
Cichero E, Buffa L, Fossa P
J Mol Model. 2011 Jul; 17(7)1537-50. doi: 10.1007/s00894-010-0857-7.

PMID:
    20922443
    [PubMed - indexed for MEDLINE]
Related citations


A new species of Aphis L (Hemiptera: Aphididae) from South Patagonia.
Delfino MA, Monelos LH, Peri PL, Buffa LM
Neotrop Entomol. 2009 May-Jun; 38(3)366-9.

PMID:
    19618053
    [PubMed - indexed for MEDLINE]
Related citations


Valsartan for prevention of recurrent atrial fibrillation.
GISSI-AF Investigators., Disertori M, Latini R, Barlera S, Franzosi MG, Staszewsky L, Maggioni AP, Lucci D, Di Pasquale G, Tognoni G
N Engl J Med. 2009 Apr 16; 360(16)1606-17. doi: 10.1056/NEJMoa0805710.

PMID:
    19369667
    [PubMed - indexed for MEDLINE]
Related citations


[Aphids on ornamental plants from Córdoba, Argentina (Hemiptera: Aphididae)].
Delfino MA, Buffa LM
Neotrop Entomol. 2008 Jan-Feb; 37(1)74-80.

PMID:
    18368253
    [PubMed - indexed for MEDLINE]
Related citations


ICA69 is a novel Rab2 effector regulating ER-Golgi trafficking in insulinoma cells.
Buffa L, Fuchs E, Pietropaolo M, Barr F, Solimena M
Eur J Cell Biol. 2008 Apr; 87(4)197-209. doi: 10.1016/j.ejcb.2007.11.003.

PMID:
    18187231
    [PubMed - indexed for MEDLINE]
Related citations


Ca2+/phospholipid-binding and syntaxin-binding of native synaptotagmin I.
Popoli M, Venegoni A, Buffa L, Racagni G
Life Sci. 1997; 61(7)711-21.

PMID:
    9252246
    [PubMed - indexed for MEDLINE]
Related citations


Long-term blockade of serotonin reuptake affects synaptotagmin phosphorylation in the hippocampus.
Popoli M, Venegoni A, Vocaturo C, Buffa L, Perez J, Smeraldi E, Racagni G
Mol Pharmacol. 1997 Jan; 51(1)19-26.

PMID:
    9016342
    [PubMed - indexed for MEDLINE]
Related citations