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Faculty Physicians

Li-Shiun Chen, MD, MPH, ScD

Instructor, Psychiatry

Specialty Areas

Schizophrenia
Mood Disorders
Adult Psychiatry

Board Certifications

Certified

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Schizophrenia, early psychosis, mood disorders, substance dependence, community psychiatry, genetics, family and sibling studies.















Dr. Chen is the adolescent & adult psychiatry assessment supervisor for the First Contact Assessment Service, which evaluates individuals who are showing early signs of a possible psychotic disorder such as schizophrenia. In addition to assessment by a psychiatrist, First Contact assessments include diagnostic interviews and cognitive testing by a psychologist. The First Contact Assessment Service generally does not follow patients over time, but provides evaluation reports to the treating psychiatrist.

  • Education
  • Publication & Research

Education

Education

Medical Degree: National Taiwan University, School of Medicine, Taipei, Taiwan 1993
Sc.D.: Psychiatric Epidemiology, Johns Hopkins University, School of Hygiene and Public Health, Baltimore, Maryland 1998
M.P.H.: Johns Hopkins University, School of Hygiene and Public Health, Baltimore, Maryland 1995

Publication & Research

Publication & Research

Protein profiling identifies mTOR pathway modulation and cytostatic effects of Pim kinase inhibitor, AZD1208, in acute myeloid leukemia.
Chen LS, Yang JY, Liang H, Cortes JE, Gandhi V
Leuk Lymphoma. 2016 Apr 7; 1-11.

PMID:
    27054578
    [PubMed - as supplied by publisher]
Related citations


Imputing Gene Expression in Uncollected Tissues Within and Beyond GTEx.
Wang J, Gamazon ER, Pierce BL, Stranger BE, Im HK, Gibbons RD, Cox NJ, Nicolae DL, Chen LS
Am J Hum Genet. 2016 Apr 7; 98(4)697-708. doi: 10.1016/j.ajhg.2016.02.020.

PMID:
    27040689
    [PubMed - in process]
Related citations


MicroRNA Regulatory Mechanisms on Citrus sinensis leaves to Magnesium-Deficiency.
Ma CL, Qi YP, Liang WW, Yang LT, Lu YB, Guo P, Ye X, Chen LS
Front Plant Sci. 2016; 7201. doi: 10.3389/fpls.2016.00201.

PMID:
    26973661
    [PubMed]
Related citations


Illumina microRNA profiles reveal the involvement of miR397a in Citrus adaptation to long-term boron toxicity via modulating secondary cell-wall biosynthesis.
Huang JH, Qi YP, Wen SX, Guo P, Chen XM, Chen LS
Sci Rep. 2016 Mar 10; 622900. doi: 10.1038/srep22900.

PMID:
    26962011
    [PubMed - in process]
Related citations


Prevalence of different HIV-1 subtypes in sexual transmission in China: a systematic review and meta-analysis.
Yuan R, Cheng H, Chen LS, Zhang X, Wang B
Epidemiol Infect. 2016 Feb 19; 1-10.

PMID:
    26892485
    [PubMed - as supplied by publisher]
Related citations


Autism genetic testing information needs among parents of affected children: A qualitative study.
Li M, Amuta A, Xu L, Dhar SU, Talwar D, Jung E, Chen LS
Patient Educ Couns. 2016 Jan 15; pii: S0738-3991(15)30159-2. doi: 10.1016/j.pec.2015.12.023.

PMID:
    26847420
    [PubMed - as supplied by publisher]
Related citations


miR-144-3p, a tumor suppressive microRNA targeting ETS-1 in laryngeal squamous cell carcinoma.
Zhang SY, Lu ZM, Lin YF, Chen LS, Luo XN, Song XH, Chen SH, Wu YL
Oncotarget. 2016 Mar 8; 7(10)11637-50. doi: 10.18632/oncotarget.7025.

PMID:
    26826553
    [PubMed - in process]
Related citations


Long-term effectiveness of school-based children oral hygiene program on oral health after 10-year follow-up.
Lai H, Fann JC, Yen AM, Chen LS, Lai MH, Chiu SY
Community Dent Oral Epidemiol. 2016 Jun; 44(3)209-15. doi: 10.1111/cdoe.12207.

PMID:
    26691608
    [PubMed - in process]
Related citations


Developmental endothelial locus-1 modulates platelet-monocyte interactions and instant blood-mediated inflammatory reaction in islet transplantation.
Kourtzelis I, Kotlabova K, Lim JH, Mitroulis I, Ferreira A, Chen LS, Gercken B, Steffen A, Kemter E, Klotzsche-von Ameln A, Waskow C, Hosur K, Chatzigeorgiou A, Ludwig B, Wolf E, Hajishengallis G, Chavakis T
Thromb Haemost. 2016 Apr 1; 115(4)781-8. doi: 10.1160/TH15-05-0429.

PMID:
    26676803
    [PubMed - in process]
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Long-term monitoring dataset of fish assemblages impinged at nuclear power plants in northern Taiwan.
Chen H, Liao YC, Chen CY, Tsai JI, Chen LS, Shao KT
Sci Data. 2015 Dec 8; 2150071. doi: 10.1038/sdata.2015.71.

PMID:
    26647085
    [PubMed - in process]
Related citations


The value of control conditions for evaluating pharmacogenetic effects.
Chen LS, Baker TB, Bierut LJ
Pharmacogenomics. 2015 Dec; 16(18)2005-6. doi: 10.2217/pgs.15.143.

PMID:
    26607722
    [PubMed - indexed for MEDLINE]
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Intermittent left cervical vagal nerve stimulation damages the stellate ganglia and reduces the ventricular rate during sustained atrial fibrillation in ambulatory dogs.
Chinda K, Tsai WC, Chan YH, Lin AY, Patel J, Zhao Y, Tan AY, Shen MJ, Lin H, Shen C, Chattipakorn N, Rubart-von der Lohe M, Chen LS, Fishbein MC, Lin SF, Chen Z, Chen PS
Heart Rhythm. 2016 Mar; 13(3)771-80. doi: 10.1016/j.hrthm.2015.11.031.

PMID:
    26607063
    [PubMed - in process]
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Root iTRAQ protein profile analysis of two Citrus species differing in aluminum-tolerance in response to long-term aluminum-toxicity.
Jiang HX, Yang LT, Qi YP, Lu YB, Huang ZR, Chen LS
BMC Genomics. 2015 Nov 16; 16(1)949. doi: 10.1186/s12864-015-2133-9.

PMID:
    26573913
    [PubMed - in process]
Related citations


Boron-deficiency-responsive microRNAs and their targets in Citrus sinensis leaves.
Lu YB, Qi YP, Yang LT, Guo P, Li Y, Chen LS
BMC Plant Biol. 2015 Nov 4; 15271. doi: 10.1186/s12870-015-0642-y.

PMID:
    26538180
    [PubMed - in process]
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Prognostic and clinical significance of syndecan-1 in colorectal cancer: a meta-analysis.
Wei HT, Guo EN, Dong BG, Chen LS
BMC Gastroenterol. 2015 Oct 30; 15152. doi: 10.1186/s12876-015-0383-2.

PMID:
    26518017
    [PubMed - in process]
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A unified set-based test with adaptive filtering for gene-environment interaction analyses.
Liu Q, Chen LS, Nicolae DL, Pierce BL
Biometrics. 2015 Oct 23; doi: 10.1111/biom.12428.

PMID:
    26496228
    [PubMed - as supplied by publisher]
Related citations


Preoperative neutrophil-to-lymphocyte ratio is an independent prognostic marker in patients with laryngeal squamous cell carcinoma.
Tu XP, Qiu QH, Chen LS, Luo XN, Lu ZM, Zhang SY, Chen SH
BMC Cancer. 2015 Oct 20; 15743. doi: 10.1186/s12885-015-1727-6.

PMID:
    26482899
    [PubMed - indexed for MEDLINE]
Related citations


When Does Choice of Accuracy Measure Alter Imputation Accuracy Assessments?
Ramnarine S, Zhang J, Chen LS, Culverhouse R, Duan W, Hancock DB, Hartz SM, Johnson EO, Olfson E, Schwantes-An TH, Saccone NL
PLoS One. 2015; 10(10)e0137601. doi: 10.1371/journal.pone.0137601.

PMID:
    26458263
    [PubMed - in process]
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Efficient Synthesis of Cladribine via the Metal-Free Deoxygenation.
Xia R, Chen LS
Nucleosides Nucleotides Nucleic Acids. 2015; 34(10)729-35. doi: 10.1080/15257770.2015.1071848.

PMID:
    26397025
    [PubMed - in process]
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Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.
Schwantes-An TH, Zhang J, Chen LS, Hartz SM, Culverhouse RC, Chen X, Coon H, Frank J, Kamens HM, Konte B, Kovanen L, Latvala A, Legrand LN, Maher BS, Melroy WE, Nelson EC, Reid MW, Robinson JD, Shen PH, Yang BZ, Andrews JA, Aveyard P, Beltcheva O, Brown SA, Cannon DS, Cichon S, Corley RP, Dahmen N, Degenhardt L, Foroud T, Gaebel W, Giegling I, Glatt SJ, Grucza RA, Hardin J, Hartmann AM, Heath AC, Herms S, Hodgkinson CA, Hoffmann P, Hops H, Huizinga D, Ising M, Johnson EO, Johnstone E, Kaneva RP, Kendler KS, Kiefer F, Kranzler HR, Krauter KS, Levran O, Lucae S, Lynskey MT, Maier W, Mann K, Martin NG, Mattheisen M, Montgomery GW, Müller-Myhsok B, Murphy MF, Neale MC, Nikolov MA, Nishita D, Nöthen MM, Nurnberger J, Partonen T, Pergadia ML, Reynolds M, Ridinger M, Rose RJ, Rouvinen-Lagerström N, Scherbaum N, Schmäl C, Soyka M, Stallings MC, Steffens M, Treutlein J, Tsuang M, Wall TL, Wodarz N, Yuferov V, Zill P, Bergen AW, Chen J, Cinciripini PM, Edenberg HJ, Ehringer MA, Ferrell RE, Gelernter J, Goldman D, Hewitt JK, Hopfer CJ, Iacono WG, Kaprio J, Kreek MJ, Kremensky IM, Madden PA, McGue M, Munafò MR, Philibert RA, Rietschel M, Roy A, Rujescu D, Saarikoski ST, Swan GE, Todorov AA, Vanyukov MM, Weiss RB, Bierut LJ, Saccone NL
Behav Genet. 2016 Mar; 46(2)151-69. doi: 10.1007/s10519-015-9737-3.

PMID:
    26392368
    [PubMed - in process]
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