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Li-Shiun Chen, MD, MPH, ScD

Instructor, Psychiatry

Specialty Areas

Schizophrenia
Mood Disorders
Adult Psychiatry

Board Certifications

Certified

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Schizophrenia, early psychosis, mood disorders, substance dependence, community psychiatry, genetics, family and sibling studies.















Dr. Chen is the adolescent & adult psychiatry assessment supervisor for the First Contact Assessment Service, which evaluates individuals who are showing early signs of a possible psychotic disorder such as schizophrenia. In addition to assessment by a psychiatrist, First Contact assessments include diagnostic interviews and cognitive testing by a psychologist. The First Contact Assessment Service generally does not follow patients over time, but provides evaluation reports to the treating psychiatrist.

  • Education
  • Publication & Research

Education

Education

Medical Degree: National Taiwan University, School of Medicine, Taipei, Taiwan 1993
Sc.D.: Psychiatric Epidemiology, Johns Hopkins University, School of Hygiene and Public Health, Baltimore, Maryland 1998
M.P.H.: Johns Hopkins University, School of Hygiene and Public Health, Baltimore, Maryland 1995

Publication & Research

Publication & Research

Triterpenoids from <i>Ganoderma lucidum</i> inhibit the activation of EBV antigens as telomerase inhibitors.
Zheng DS, Chen LS
Exp Ther Med. 2017 Oct; 14(4)3273-3278. doi: 10.3892/etm.2017.4883.

PMID:
    28912878
    [PubMed]
Related citations


Long-term manganese-toxicity-induced alterations of physiology and leaf protein profiles in two Citrus species differing in manganese-tolerance.
You X, Yang LT, Qi YP, Guo P, Lai NW, Ye X, Li Q, Chen LS
J Plant Physiol. 2017 Sep 2; 218249-257. doi: 10.1016/j.jplph.2017.08.011.

PMID:
    28910703
    [PubMed - as supplied by publisher]
Related citations


Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche.
Mitroulis I, Chen LS, Singh RP, Kourtzelis I, Economopoulou M, Kajikawa T, Troullinaki M, Ziogas A, Ruppova K, Hosur K, Maekawa T, Wang B, Subramanian P, Tonn T, Verginis P, von Bonin M, Wobus M, Bornhäuser M, Grinenko T, Di Scala M, Hidalgo A, Wielockx B, Hajishengallis G, Chavakis T
J Clin Invest. 2017 Aug 28; pii: 92571. doi: 10.1172/JCI92571.

PMID:
    28846069
    [PubMed - as supplied by publisher]
Related citations


MicroRNA-mediated responses to long-term magnesium-deficiency in Citrus sinensis roots revealed by Illumina sequencing.
Liang WW, Huang JH, Li CP, Yang LT, Ye X, Lin D, Chen LS
BMC Genomics. 2017 Aug 24; 18(1)657. doi: 10.1186/s12864-017-3999-5.

PMID:
    28836935
    [PubMed - in process]
Related citations


Left cervical vagal nerve stimulation reduces skin sympathetic nerve activity in patients with drug resistant epilepsy.
Yuan Y, Hassel JL, Doytchinova A, Adams D, Wright KC, Meshberger C, Chen LS, Guerra MP, Shen C, Lin SF, Everett TH 4th, Salanova V, Chen PS
Heart Rhythm. 2017 Aug 1; pii: S1547-5271(17)30960-8. doi: 10.1016/j.hrthm.2017.07.035.

PMID:
    28778733
    [PubMed - as supplied by publisher]
Related citations


Association Between Substance Use Disorder and Polygenic Liability to Schizophrenia.
Hartz SM, Horton AC, Oehlert M, Carey CE, Agrawal A, Bogdan R, Chen LS, Hancock DB, Johnson EO, Pato CN, Pato MT, Rice JP, Bierut LJ
Biol Psychiatry. 2017 Jun 6; pii: S0006-3223(17)31624-4. doi: 10.1016/j.biopsych.2017.04.020.

PMID:
    28739213
    [PubMed - as supplied by publisher]
Related citations


Chlorinated adenosine analogue induces AMPK and autophagy in chronic lymphocytic leukaemia cells during therapy.
Stellrecht CM, Chen LS, Ayres ML, Dennison JB, Shentu S, Chen Y, Keating MJ, Wierda WG, Gandhi V
Br J Haematol. 2017 Jul 24; doi: 10.1111/bjh.14859.

PMID:
    28737232
    [PubMed - as supplied by publisher]
Related citations


Simultaneous recordings of intrinsic cardiac nerve activity and skin sympathetic nerve activity from human patients during the postoperative period.
Shen MJ, Coffey AC, Straka S, Adams DE, Wagner DB, Kovacs RJ, Clark M, Shen C, Chen LS, Everett TH 4th, Lin SF, Chen PS
Heart Rhythm. 2017 Jun 23; pii: S1547-5271(17)30779-8. doi: 10.1016/j.hrthm.2017.06.030.

PMID:
    28648667
    [PubMed - as supplied by publisher]
Related citations


Magnesium-deficiency-induced alterations of gas exchange, major metabolites and key enzymes differ among roots, and lower and upper leaves of Citrus sinensis seedlings.
Li CP, Qi YP, Zhang J, Yang LT, Wang DH, Ye X, Lai NW, Tan LL, Lin D, Chen LS
Tree Physiol. 2017 Jun 14; 1-18. doi: 10.1093/treephys/tpx067.

PMID:
    28633366
    [PubMed - as supplied by publisher]
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The association between telomere length and mortality in Bangladesh.
Dean SG, Zhang C, Gao J, Roy S, Shinkle J, Sabarinathan M, Argos M, Tong L, Ahmed A, Islam MT, Islam T, Rakibuz-Zaman M, Sarwar G, Shahriar H, Rahman M, Yunus M, Graziano JH, Chen LS, Jasmine F, Kibriya MG, Ahsan H, Pierce BL
Aging (Albany NY). 2017 Jun 15; 9(6)1537-1551. doi: 10.18632/aging.101246.

PMID:
    28630379
    [PubMed - in process]
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The secular trends of disease burden attributed to tobacco smoke in Taiwan 1990-2013.
Chen LS, Hurng BS
J Formos Med Assoc. 2017 May 23; pii: S0929-6646(17)30071-2. doi: 10.1016/j.jfma.2017.05.003.

PMID:
    28549590
    [PubMed - as supplied by publisher]
Related citations


Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study / Study of Latinos (HCHS/SOL).
Saccone NL, Emery LS, Sofer T, Gogarten SM, Becker DM, Bottinger EP, Chen LS, Culverhouse RC, Duan W, Hancock DB, Hosgood HD, Johnson EO, Loos RJF, Louie T, Papanicolaou G, Perreira KM, Rodriquez EJ, Schurmann C, Stilp AM, Szpiro AA, Talavera GA, Taylor KD, Thrasher JF, Yanek LR, Laurie CC, Pérez-Stable EJ, Bierut LJ, Kaplan RC
Nicotine Tob Res. 2017 May 17; doi: 10.1093/ntr/ntx107.

PMID:
    28520984
    [PubMed - as supplied by publisher]
Related citations


Expression of aromatase and estrogen receptors in lumbar motoneurons of mice.
Ji YX, Zhao M, Liu YL, Chen LS, Hao PL, Sun C
Neurosci Lett. 2017 Jul 13; 6537-11. doi: 10.1016/j.neulet.2017.05.017.

PMID:
    28501695
    [PubMed - in process]
Related citations


Leveraging genomic data in smoking cessation trials in the era of Precision Medicine: Why and how.
Chen LS, Zawertailo L, Piasecki TM, Kaprio J, Foreman M, Elliott HR, David SP, Bergen AW, Baurley JW, Tyndale RF, Baker TB, Bierut LJ, Saccone NL, Genetics and Treatment Workgroup of the Society for Research on Nicotine and Tobacco (SRNT).
Nicotine Tob Res. 2017 May 12; doi: 10.1093/ntr/ntx097.

PMID:
    28498934
    [PubMed - as supplied by publisher]
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The Value of Biosamples in Smoking Cessation Trials: A Review of Genetic, Metabolomic, and Epigenetic Findings.
Saccone NL, Baurley JW, Bergen AW, David SP, Elliott HR, Foreman MG, Kaprio J, Piasecki TM, Relton CL, Zawertailo L, Bierut LJ, Tyndale RF, Chen LS, Genetics and Treatment Networks of the Society for Research on Nicotine and Tobacco (SRNT).
Nicotine Tob Res. 2017 May 3; doi: 10.1093/ntr/ntx096.

PMID:
    28472521
    [PubMed - as supplied by publisher]
Related citations


Skin sympathetic nerve activity precedes the onset and termination of paroxysmal atrial tachycardia and fibrillation.
Uradu A, Wan J, Doytchinova A, Wright KC, Lin AYT, Chen LS, Shen C, Lin SF, Everett TH 4th, Chen PS
Heart Rhythm. 2017 Jul; 14(7)964-971. doi: 10.1016/j.hrthm.2017.03.030.

PMID:
    28347833
    [PubMed - in process]
Related citations


Root Adaptive Responses to Aluminum-Treatment Revealed by RNA-Seq in Two Citrus Species With Different Aluminum-Tolerance.
Guo P, Qi YP, Yang LT, Lai NW, Ye X, Yang Y, Chen LS
Front Plant Sci. 2017; 8330. doi: 10.3389/fpls.2017.00330.

PMID:
    28337215
    [PubMed]
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Genetic correlation between smoking behaviors and schizophrenia.
Hartz SM, Horton AC, Hancock DB, Baker TB, Caporaso NE, Chen LS, Hokanson JE, Lutz SM, Marazita ML, McNeil DW, Pato CN, Pato MT, Johnson EO, Bierut LJ
Schizophr Res. 2017 Mar 8; pii: S0920-9964(17)30111-1. doi: 10.1016/j.schres.2017.02.022.

PMID:
    28285025
    [PubMed - as supplied by publisher]
Related citations


Effects of Low pH on Photosynthesis, Related Physiological Parameters, and Nutrient Profiles of <i>Citrus</i>.
Long A, Zhang J, Yang LT, Ye X, Lai NW, Tan LL, Lin D, Chen LS
Front Plant Sci. 2017; 8185. doi: 10.3389/fpls.2017.00185.

PMID:
    28270819
    [PubMed]
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Effects of High Toxic Boron Concentration on Protein Profiles in Roots of Two Citrus Species Differing in Boron-Tolerance Revealed by a 2-DE Based MS Approach.
Sang W, Huang ZR, Yang LT, Guo P, Ye X, Chen LS
Front Plant Sci. 2017; 8180. doi: 10.3389/fpls.2017.00180.

PMID:
    28261239
    [PubMed]
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