Patient Portal

Leonel F. Hernandez-Aya, MD

Assistant Professor, Medicine
Division of Medical Oncology

Specialty Areas

Breast Cancer
Melanoma
Medical Oncology

Board Certifications

Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Languages

Spanish

Areas of Clinical Interest

Breast cancer, melanoma, cancer immunotherapy

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Siteman Cancer Center

4921 Parkview Place
St. Louis, MO 63110

Education

Education

Fellowship, Hematology/Oncology : University of Michigan Health System, Comprehensive Cancer Center, Ann Arbor, MI 2015
Residency, Internal Medicine: University of Miami Miller School of Medicine, Miami, FL 2012
Medical Degree: Universidad Nacional de Colombia School of Medicine, Bogota, Colombia 2007

Publication & Research

Publication & Research

Quantitative Spatial Profiling of PD-1/PD-L1 Interaction and HLA-DR/IDO-1 Predicts Improved Outcomes of anti-PD-1 Therapies in Metastatic Melanoma.
Johnson DB, Bordeaux JM, Kim JY, Vaupel CA, Rimm DL, Ho TH, Joseph RW, Daud AI, Conry RM, Gaughan EM, Hernandez-Aya LF, Dimou A, Funchain P, Smithy JW, Witte JS, McKee SB, Ko J, Wrangle J, Dabbas B, Tangri S, Lameh J, Hall JM, Markowitz J, Balko JM, Dakappagari NK
Clin Cancer Res. 2018 Jul 18; pii: clincanres.0309.2018. doi: 10.1158/1078-0432.CCR-18-0309.

PMID:
    30021908
    [PubMed - as supplied by publisher]
Related citations


Stereotactic radiosurgery and immunotherapy in melanoma brain metastases: Patterns of care and treatment outcomes.
Gabani P, Fischer-Valuck BW, Johanns TM, Hernandez-Aya LF, Keller JW, Rich KM, Kim AH, Dunn GP, Robinson CG, Chicoine MR, Huang J, Abraham CD
Radiother Oncol. 2018 Aug; 128(2)266-273. doi: 10.1016/j.radonc.2018.06.017.

PMID:
    29960685
    [PubMed - in process]
Related citations


Chemotherapy principles of managing stage IV breast cancer in the United States.
Hernandez-Aya LF, Ma CX
Chin Clin Oncol. 2016 Jun; 5(3)42. doi: 10.21037/cco.2016.04.01.

PMID:
    27164855
    [PubMed - indexed for MEDLINE]
Related citations


Why Chemotherapy Should be Given Early for Men with Metastatic Prostate Cancer.
Hernandez-Aya LF, Hussain M
Am Soc Clin Oncol Educ Book. 2015; e263-9. doi: 10.14694/EdBook_AM.2015.35.e263.

PMID:
    25993184
    [PubMed - indexed for MEDLINE]
Related citations


A meta-analysis on the prophylactic use of macrolide antibiotics for the prevention of disease exacerbations in patients with Chronic Obstructive Pulmonary Disease.
Donath E, Chaudhry A, Hernandez-Aya LF, Lit L
Respir Med. 2013 Sep; 107(9)1385-92. doi: 10.1016/j.rmed.2013.05.004.

PMID:
    23768735
    [PubMed - indexed for MEDLINE]
Related citations


Adjuvant systemic therapies in breast cancer.
Hernandez-Aya LF, Gonzalez-Angulo AM
Surg Clin North Am. 2013 Apr; 93(2)473-91. doi: 10.1016/j.suc.2012.12.002.

PMID:
    23464697
    [PubMed - indexed for MEDLINE]
Related citations


Triple-negative breast cancer is not a contraindication for breast conservation.
Adkins FC, Gonzalez-Angulo AM, Lei X, Hernandez-Aya LF, Mittendorf EA, Litton JK, Wagner J, Hunt KK, Woodward WA, Meric-Bernstam F
Ann Surg Oncol. 2011 Oct; 18(11)3164-73. doi: 10.1245/s10434-011-1920-z.

PMID:
    21947595
    [PubMed - indexed for MEDLINE]
Related citations


Impact of low estrogen/progesterone receptor expression on survival outcomes in breast cancers previously classified as triple negative breast cancers.
Raghav KP, Hernandez-Aya LF, Lei X, Chavez-Macgregor M, Meric-Bernstam F, Buchholz TA, Sahin A, Do KA, Hortobagyi GN, Gonzalez-Angulo AM
Cancer. 2012 Mar 15; 118(6)1498-506. doi: 10.1002/cncr.26431.

PMID:
    21837669
    [PubMed - indexed for MEDLINE]
Related citations


Nodal status and clinical outcomes in a large cohort of patients with triple-negative breast cancer.
Hernandez-Aya LF, Chavez-Macgregor M, Lei X, Meric-Bernstam F, Buchholz TA, Hsu L, Sahin AA, Do KA, Valero V, Hortobagyi GN, Gonzalez-Angulo AM
J Clin Oncol. 2011 Jul 1; 29(19)2628-34. doi: 10.1200/JCO.2010.32.1877.

PMID:
    21606433
    [PubMed - indexed for MEDLINE]
Related citations


Targeting the phosphatidylinositol 3-kinase signaling pathway in breast cancer.
Hernandez-Aya LF, Gonzalez-Angulo AM
Oncologist. 2011; 16(4)404-14. doi: 10.1634/theoncologist.2010-0402.

PMID:
    21406469
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Cancer Immunotherapy, cancer microenvironment, breast cancer research, melanoma clinical research