Patient Portal

Leonel F. Hernandez-Aya, MD

Assistant Professor, Medicine
Division of Medical Oncology

Specialty Areas

Breast Cancer
Melanoma
Medical Oncology

Board Certifications

Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Languages

Spanish

Areas of Clinical Interest

Breast cancer, melanoma, cancer immunotherapy

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Siteman Cancer Center

4921 Parkview Place
St. Louis, MO 63110

Education

Education

Fellowship, Hematology/Oncology : University of Michigan Health System, Comprehensive Cancer Center, Ann Arbor, MI 2015
Residency, Internal Medicine: University of Miami Miller School of Medicine, Miami, FL 2012
Medical Degree: Universidad Nacional de Colombia School of Medicine, Bogota, Colombia 2007

Publication & Research

Publication & Research

Quantitative Spatial Profiling of PD-1/PD-L1 Interaction and HLA-DR/IDO-1 Predicts Improved Outcomes of Anti-PD-1 Therapies in Metastatic Melanoma.
Johnson DB, Bordeaux J, Kim JY, Vaupel C, Rimm DL, Ho TH, Joseph RW, Daud AI, Conry RM, Gaughan EM, Hernandez-Aya LF, Dimou A, Funchain P, Smithy J, Witte JS, McKee SB, Ko J, Wrangle JM, Dabbas B, Tangri S, Lameh J, Hall J, Markowitz J, Balko JM, Dakappagari N
Clin Cancer Res. 2018 Nov 1; 24(21)5250-5260. doi: 10.1158/1078-0432.CCR-18-0309.

PMID:
    30021908
    [PubMed - in process]
Related citations


Stereotactic radiosurgery and immunotherapy in melanoma brain metastases: Patterns of care and treatment outcomes.
Gabani P, Fischer-Valuck BW, Johanns TM, Hernandez-Aya LF, Keller JW, Rich KM, Kim AH, Dunn GP, Robinson CG, Chicoine MR, Huang J, Abraham CD
Radiother Oncol. 2018 Aug; 128(2)266-273. doi: 10.1016/j.radonc.2018.06.017.

PMID:
    29960685
    [PubMed - indexed for MEDLINE]
Related citations


Chemotherapy principles of managing stage IV breast cancer in the United States.
Hernandez-Aya LF, Ma CX
Chin Clin Oncol. 2016 Jun; 5(3)42. doi: 10.21037/cco.2016.04.01.

PMID:
    27164855
    [PubMed - indexed for MEDLINE]
Related citations


Why Chemotherapy Should be Given Early for Men with Metastatic Prostate Cancer.
Hernandez-Aya LF, Hussain M
Am Soc Clin Oncol Educ Book. 2015; e263-9. doi: 10.14694/EdBook_AM.2015.35.e263.

PMID:
    25993184
    [PubMed - indexed for MEDLINE]
Related citations


A meta-analysis on the prophylactic use of macrolide antibiotics for the prevention of disease exacerbations in patients with Chronic Obstructive Pulmonary Disease.
Donath E, Chaudhry A, Hernandez-Aya LF, Lit L
Respir Med. 2013 Sep; 107(9)1385-92. doi: 10.1016/j.rmed.2013.05.004.

PMID:
    23768735
    [PubMed - indexed for MEDLINE]
Related citations


Adjuvant systemic therapies in breast cancer.
Hernandez-Aya LF, Gonzalez-Angulo AM
Surg Clin North Am. 2013 Apr; 93(2)473-91. doi: 10.1016/j.suc.2012.12.002.

PMID:
    23464697
    [PubMed - indexed for MEDLINE]
Related citations


Triple-negative breast cancer is not a contraindication for breast conservation.
Adkins FC, Gonzalez-Angulo AM, Lei X, Hernandez-Aya LF, Mittendorf EA, Litton JK, Wagner J, Hunt KK, Woodward WA, Meric-Bernstam F
Ann Surg Oncol. 2011 Oct; 18(11)3164-73. doi: 10.1245/s10434-011-1920-z.

PMID:
    21947595
    [PubMed - indexed for MEDLINE]
Related citations


Impact of low estrogen/progesterone receptor expression on survival outcomes in breast cancers previously classified as triple negative breast cancers.
Raghav KP, Hernandez-Aya LF, Lei X, Chavez-Macgregor M, Meric-Bernstam F, Buchholz TA, Sahin A, Do KA, Hortobagyi GN, Gonzalez-Angulo AM
Cancer. 2012 Mar 15; 118(6)1498-506. doi: 10.1002/cncr.26431.

PMID:
    21837669
    [PubMed - indexed for MEDLINE]
Related citations


Nodal status and clinical outcomes in a large cohort of patients with triple-negative breast cancer.
Hernandez-Aya LF, Chavez-Macgregor M, Lei X, Meric-Bernstam F, Buchholz TA, Hsu L, Sahin AA, Do KA, Valero V, Hortobagyi GN, Gonzalez-Angulo AM
J Clin Oncol. 2011 Jul 1; 29(19)2628-34. doi: 10.1200/JCO.2010.32.1877.

PMID:
    21606433
    [PubMed - indexed for MEDLINE]
Related citations


Targeting the phosphatidylinositol 3-kinase signaling pathway in breast cancer.
Hernandez-Aya LF, Gonzalez-Angulo AM
Oncologist. 2011; 16(4)404-14. doi: 10.1634/theoncologist.2010-0402.

PMID:
    21406469
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Cancer Immunotherapy, cancer microenvironment, breast cancer research, melanoma clinical research