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Faculty Physicians

Leonard B. Bacharier, MD

Professor, Pediatrics
Clinical Director, Division of Allergy, Immunology and Pulmonary Medicine

Specialty Areas

Pediatric Allergy
Pediatric Immunology
Pediatric Asthma
Cystic Fibrosis

Board Certifications

Allergy & Clinical Immunology
Pediatrics

Hospital Affiliations

Missouri Baptist Medical Center
Barnes-Jewish West County Hospital
St. Louis Children's Hospital

Referral Information

Physician Referral Required

Areas of Clinical Interest

Asthma in children, allergy and lung disease in children, immunology

  • Maps & Directions
  • Education
  • Publication & Research
  • Financial Disclosures

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: Suite C
Floor: 2nd Floor
Office Phone: 314-454-2694

Barnes-Jewish West County Hospital
Medical Building Three

1020 N. Mason Road
St. Louis, MO 63141

Suite: Suite 110
Office Phone: 314-454-2694
Fax: 314-454-2219

Education

Education

Fellowship: Pediatric Allergy and Immunology, Children's Hospital, Boston, Massachusetts
Residency: Pediatrics, St. Louis Children's Hospital, St. Louis, Missouri 1995
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1992
B.S.: Biophysics, The Johns Hopkins University, Baltimore, Maryland

Publication & Research

Publication & Research

Temporal biological variability in dendritic cells and regulatory T cells in peripheral blood of healthy adults.
Kitcharoensakkul M, Bacharier LB, Yin-Declue H, Boomer JS, Burgdorf D, Wilson B, Schechtman K, Castro M
J Immunol Methods. 2016 Feb 6; pii: S0022-1759(16)30021-7. doi: 10.1016/j.jim.2016.02.006.

PMID:
    26859243
    [PubMed - as supplied by publisher]
Related citations


Early-life respiratory infections and asthma development: role in disease pathogenesis and potential targets for disease prevention.
Beigelman A, Bacharier LB
Curr Opin Allergy Clin Immunol. 2016 Feb 5;

PMID:
    26854761
    [PubMed - as supplied by publisher]
Related citations


Effect of Prenatal Supplementation With Vitamin D on Asthma or Recurrent Wheezing in Offspring by Age 3 Years: The VDAART Randomized Clinical Trial.
Litonjua AA, Carey VJ, Laranjo N, Harshfield BJ, McElrath TF, O'Connor GT, Sandel M, Iverson RE Jr, Lee-Paritz A, Strunk RC, Bacharier LB, Macones GA, Zeiger RS, Schatz M, Hollis BW, Hornsby E, Hawrylowicz C, Wu AC, Weiss ST
JAMA. 2016 Jan 26; 315(4)362-70. doi: 10.1001/jama.2015.18589.

PMID:
    26813209
    [PubMed - indexed for MEDLINE]
Related citations


Identification of infants and preschool children at risk for asthma: predictive scores and biomarkers.
Wandalsen GF, Solé D, Bacharier LB
Curr Opin Allergy Clin Immunol. 2016 Jan 22;

PMID:
    26807784
    [PubMed - as supplied by publisher]
Related citations


Management of Preschool Children with Recurrent Wheezing: Lessons from the NHLBI's Asthma Research Networks.
Beigelman A, Bacharier LB
J Allergy Clin Immunol Pract. 2016 Jan-Feb; 4(1)1-8. doi: 10.1016/j.jaip.2015.10.003.

PMID:
    26772922
    [PubMed - in process]
Related citations


The recurrently wheezing preschool child-benign or asthma in the making?
Bacharier LB
Ann Allergy Asthma Immunol. 2015 Dec; 115(6)463-70. doi: 10.1016/j.anai.2015.09.019.

PMID:
    26653278
    [PubMed - in process]
Related citations


Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy.
Torgerson DG, Giri T, Druley TE, Zheng J, Huntsman S, Seibold MA, Young AL, Schweiger T, Yin-Declue H, Sajol GD, Schechtman KB, Hernandez RD, Randolph AG, Bacharier LB, Castro M
PLoS One. 2015; 10(11)e0142649. doi: 10.1371/journal.pone.0142649.

PMID:
    26587832
    [PubMed - in process]
Related citations


Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial.
Bacharier LB, Guilbert TW, Mauger DT, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CA, Cabana M, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF Jr, Ly N, Meade K, Morgan W, Moy J, Olin T, Peters SP, Phipatanakul W, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Szefler SJ, Teague WG, Thyne S, Martinez FD, National Heart, Lung, and Blood Institute’s AsthmaNet
JAMA. 2015 Nov 17; 314(19)2034-44. doi: 10.1001/jama.2015.13896.

PMID:
    26575060
    [PubMed - indexed for MEDLINE]
Related citations


Vitamin D Levels Are Unrelated to the Severity of Respiratory Syncytial Virus Bronchiolitis Among Hospitalized Infants.
Beigelman A, Castro M, Schweiger TL, Wilson BS, Zheng J, Yin-DeClue H, Sajol G, Giri T, Sierra OL, Isaacson-Schmid M, Sumino K, Schechtman KB, Bacharier LB
J Pediatric Infect Dis Soc. 2015 Sep; 4(3)182-8. doi: 10.1093/jpids/piu042.

PMID:
    26336601
    [PubMed - in process]
Related citations


Update on the utility of corticosteroids in acute pediatric respiratory disorders.
Beigelman A, Chipps BE, Bacharier LB
Allergy Asthma Proc. 2015 Sep-Oct; 36(5)332-8. doi: 10.2500/aap.2015.36.3865.

PMID:
    26314814
    [PubMed - in process]
Related citations


Reply: To PMID 25458910.
Beigelman A, Bacharier LB
J Allergy Clin Immunol. 2015 Oct; 136(4)1135-6. doi: 10.1016/j.jaci.2015.07.013.

PMID:
    26309182
    [PubMed - indexed for MEDLINE]
Related citations


Does azithromycin modify viral load during severe respiratory syncytial virus bronchiolitis?
Beigelman A, Bacharier LB, Baty J, Buller R, Mason S, Schechtman KB, Sajol G, Isaacson-Schmid M, Castro M, Storch GA
J Allergy Clin Immunol. 2015 Oct; 136(4)1129-31. doi: 10.1016/j.jaci.2015.06.011.

PMID:
    26215052
    [PubMed - indexed for MEDLINE]
Related citations


Airway Obstruction Worsens in Young Adults with Asthma Who Become Obese.
Strunk RC, Colvin R, Bacharier LB, Fuhlbrigge A, Forno E, Arbelaez AM, Tantisira KG, Childhood Asthma Management Program Research Group
J Allergy Clin Immunol Pract. 2015 Sep-Oct; 3(5)765-71.e2. doi: 10.1016/j.jaip.2015.05.009.

PMID:
    26164807
    [PubMed - in process]
Related citations


Severe asthma in school-age children: evaluation and phenotypic advances.
Coverstone A, Bacharier LB, Fitzpatrick AM
Curr Allergy Asthma Rep. 2015 May; 15(5)20. doi: 10.1007/s11882-015-0521-5.

PMID:
    26134431
    [PubMed - indexed for MEDLINE]
Related citations


Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma.
Gerald JK, Gerald LB, Vasquez MM, Morgan WJ, Boehmer SJ, Lemanske RF Jr, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bade E, Covar RA, Guilbert TW, Heidarian-Raissy H, Kelly HW, Malka-Rais J, Sorkness CA, Taussig LM, Chinchilli VM, Martinez FD
J Allergy Clin Immunol Pract. 2015 Jul-Aug; 3(4)540-6.e3. doi: 10.1016/j.jaip.2015.01.023.

PMID:
    25783161
    [PubMed - in process]
Related citations


Randomized trial to evaluate azithromycin's effects on serum and upper airway IL-8 levels and recurrent wheezing in infants with respiratory syncytial virus bronchiolitis.
Beigelman A, Isaacson-Schmid M, Sajol G, Baty J, Rodriguez OM, Leege E, Lyons K, Schweiger TL, Zheng J, Schechtman KB, Castro M, Bacharier LB
J Allergy Clin Immunol. 2015 May; 135(5)1171-8.e1. doi: 10.1016/j.jaci.2014.10.001.

PMID:
    25458910
    [PubMed - indexed for MEDLINE]
Related citations


Severe asthma in children.
Guilbert TW, Bacharier LB, Fitzpatrick AM
J Allergy Clin Immunol Pract. 2014 Sep-Oct; 2(5)489-500. doi: 10.1016/j.jaip.2014.06.022.

PMID:
    25213041
    [PubMed - indexed for MEDLINE]
Related citations


Management of acute loss of asthma control in the yellow zone: a practice parameter.
Dinakar C, Oppenheimer J, Portnoy J, Bacharier LB, Li J, Kercsmar CM, Bernstein D, Blessing-Moore J, Khan D, Lang D, Nicklas R, Randolph C, Schuller D, Spector S, Tilles SA, Wallace D, Joint Task Force on Practice Parameters, Practice Parameter Workgroup, American Academy of Allergy, Asthma and Immunology, American College of Allergy, Asthma and Immunology
Ann Allergy Asthma Immunol. 2014 Aug; 113(2)143-59. doi: 10.1016/j.anai.2014.05.017.

PMID:
    25065350
    [PubMed - indexed for MEDLINE]
Related citations


Longitudinal changes in airway remodeling and air trapping in severe asthma.
Witt CA, Sheshadri A, Carlstrom L, Tarsi J, Kozlowski J, Wilson B, Gierada DS, Hoffman E, Fain SB, Cook-Granroth J, Sajol G, Sierra O, Giri T, O'Neill M, Zheng J, Schechtman KB, Bacharier LB, Jarjour N, Busse W, Castro M, NHLBI Severe Asthma Research Program (SARP)
Acad Radiol. 2014 Aug; 21(8)986-93. doi: 10.1016/j.acra.2014.05.001.

PMID:
    25018070
    [PubMed - indexed for MEDLINE]
Related citations


Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children.
Lynch SV, Wood RA, Boushey H, Bacharier LB, Bloomberg GR, Kattan M, O'Connor GT, Sandel MT, Calatroni A, Matsui E, Johnson CC, Lynn H, Visness CM, Jaffee KF, Gergen PJ, Gold DR, Wright RJ, Fujimura K, Rauch M, Busse WW, Gern JE
J Allergy Clin Immunol. 2014 Sep; 134(3)593-601.e12. doi: 10.1016/j.jaci.2014.04.018.

PMID:
    24908147
    [PubMed - indexed for MEDLINE]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2014.

Company Name: DBV Technologies

Royalties:

Equity: No

Consulting/Advisory Board: $10,001 - $25,000

Speaker Fees:

Reporting Date: May 01, 2015

Areas of Research Interest

Dr. Bacharier's research focuses on childhood asthma. Specifically, he is co-principal investigator for the NHBLI’s AsthmaNet, a multi-centered network examining novel therapeutic approaches to asthma in children and adults. He is an investigator in the Childhood Asthma Research and Education (CARE) Network, an NHLBI-funded multi-centered network examining novel therapeutic strategies in children with asthma. He is a co-investigator in the Childhood Asthma Management Program, a multi-centered prospective trial examining the effects of early treatment of asthma on lung growth. He also serves as Co-Principal Investigator of a study examining the role of early infection with Respiratory Syncytial Virus upon the subsequent development of asthma.