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Faculty Physicians

Leonard B. Bacharier, MD

Professor, Pediatrics
Clinical Director, Division of Allergy, Immunology and Pulmonary Medicine

Specialty Areas

Pediatric Allergy
Pediatric Immunology
Pediatric Asthma
Cystic Fibrosis

Board Certifications

Allergy & Clinical Immunology
Pediatrics

Referral Information

Physician Referral Required

Hospital Affiliations

Missouri Baptist Medical Center
Barnes-Jewish West County Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Asthma in children, allergy and lung disease in children, immunology

  • Maps & Directions
  • Education
  • Publication & Research
  • Financial Disclosures

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: Suite C
Floor: 2nd Floor
Office Phone: 314-454-2694

Barnes-Jewish West County Hospital
Medical Building Three

1020 N. Mason Road
St. Louis, MO 63141

Suite: Suite 110
Office Phone: 314-454-2694
Fax: 314-454-2219

Education

Education

Fellowship: Pediatric Allergy and Immunology, Children's Hospital, Boston, Massachusetts
Residency: Pediatrics, St. Louis Children's Hospital, St. Louis, Missouri 1995
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1992
B.S.: Biophysics, The Johns Hopkins University, Baltimore, Maryland

Publication & Research

Publication & Research

Randomized trial to evaluate azithromycin's effects on serum and upper airway IL-8 levels and recurrent wheezing in infants with respiratory syncytial virus bronchiolitis.
Beigelman A, Isaacson-Schmid M, Sajol G, Baty J, Rodriguez OM, Leege E, Lyons K, Schweiger TL, Zheng J, Schechtman KB, Castro M, Bacharier LB
J Allergy Clin Immunol. 2015 May; 135(5)1171-8.e1. doi: 10.1016/j.jaci.2014.10.001.

PMID:
    25458910
    [PubMed - indexed for MEDLINE]
Related citations


Severe asthma in children.
Guilbert TW, Bacharier LB, Fitzpatrick AM
J Allergy Clin Immunol Pract. 2014 Sep-Oct; 2(5)489-500. doi: 10.1016/j.jaip.2014.06.022.

PMID:
    25213041
    [PubMed - indexed for MEDLINE]
Related citations


Management of acute loss of asthma control in the yellow zone: a practice parameter.
Dinakar C, Oppenheimer J, Portnoy J, Bacharier LB, Li J, Kercsmar CM, Bernstein D, Blessing-Moore J, Khan D, Lang D, Nicklas R, Randolph C, Schuller D, Spector S, Tilles SA, Wallace D, Joint Task Force on Practice Parameters, Practice Parameter Workgroup, American Academy of Allergy, Asthma and Immunology, American College of Allergy, Asthma and Immunology
Ann Allergy Asthma Immunol. 2014 Aug; 113(2)143-59. doi: 10.1016/j.anai.2014.05.017.

PMID:
    25065350
    [PubMed - indexed for MEDLINE]
Related citations


Longitudinal changes in airway remodeling and air trapping in severe asthma.
Witt CA, Sheshadri A, Carlstrom L, Tarsi J, Kozlowski J, Wilson B, Gierada DS, Hoffman E, Fain SB, Cook-Granroth J, Sajol G, Sierra O, Giri T, O'Neill M, Zheng J, Schechtman KB, Bacharier LB, Jarjour N, Busse W, Castro M, NHLBI Severe Asthma Research Program (SARP)
Acad Radiol. 2014 Aug; 21(8)986-93. doi: 10.1016/j.acra.2014.05.001.

PMID:
    25018070
    [PubMed - indexed for MEDLINE]
Related citations


Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children.
Lynch SV, Wood RA, Boushey H, Bacharier LB, Bloomberg GR, Kattan M, O'Connor GT, Sandel MT, Calatroni A, Matsui E, Johnson CC, Lynn H, Visness CM, Jaffee KF, Gergen PJ, Gold DR, Wright RJ, Fujimura K, Rauch M, Busse WW, Gern JE
J Allergy Clin Immunol. 2014 Sep; 134(3)593-601.e12. doi: 10.1016/j.jaci.2014.04.018.

PMID:
    24908147
    [PubMed - indexed for MEDLINE]
Related citations


Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial.
Castro M, King TS, Kunselman SJ, Cabana MD, Denlinger L, Holguin F, Kazani SD, Moore WC, Moy J, Sorkness CA, Avila P, Bacharier LB, Bleecker E, Boushey HA, Chmiel J, Fitzpatrick AM, Gentile D, Hundal M, Israel E, Kraft M, Krishnan JA, LaForce C, Lazarus SC, Lemanske R, Lugogo N, Martin RJ, Mauger DT, Naureckas E, Peters SP, Phipatanakul W, Que LG, Sheshadri A, Smith L, Solway J, Sullivan-Vedder L, Sumino K, Wechsler ME, Wenzel S, White SR, Sutherland ER, National Heart, Lung, and Blood Institute’s AsthmaNet
JAMA. 2014 May; 311(20)2083-91. doi: 10.1001/jama.2014.5052.

PMID:
    24838406
    [PubMed - indexed for MEDLINE]
Related citations


Early-life weight gain, prematurity, and asthma development.
Bacharier LB
J Allergy Clin Immunol. 2014 May; 133(5)1330-1. doi: 10.1016/j.jaci.2014.03.005.

PMID:
    24766877
    [PubMed - indexed for MEDLINE]
Related citations


Opportunities to diagnose chronic obstructive pulmonary disease in routine care in the UK: a retrospective study of a clinical cohort.
Jones RC, Price D, Ryan D, Sims EJ, von Ziegenweidt J, Mascarenhas L, Burden A, Halpin DM, Winter R, Hill S, Kearney M, Holton K, Moger A, Freeman D, Chisholm A, Bateman ED, Respiratory Effectiveness Group
Lancet Respir Med. 2014 Apr; 2(4)267-76. doi: 10.1016/S2213-2600(14)70008-6.

PMID:
    24717623
    [PubMed - indexed for MEDLINE]
Related citations


The association between vitamin D status and the rate of exacerbations requiring oral corticosteroids in preschool children with recurrent wheezing.
Beigelman A, Zeiger RS, Mauger D, Strunk RC, Jackson DJ, Martinez FD, Morgan WJ, Covar R, Szefler SJ, Taussig LM, Bacharier LB, Childhood Asthma Research and Education (CARE) Network of the National Heart, Lung, and Blood Institute
J Allergy Clin Immunol. 2014 May; 133(5)1489-92, 1492.e1-3. doi: 10.1016/j.jaci.2014.02.024.

PMID:
    24698320
    [PubMed - indexed for MEDLINE]
Related citations


Infection-induced wheezing in young children.
Beigelman A, Bacharier LB
J Allergy Clin Immunol. 2014 Feb; 133(2)603-4. doi: 10.1016/j.jaci.2013.12.001.

PMID:
    24636478
    [PubMed - indexed for MEDLINE]
Related citations


Birth cohorts in asthma and allergic diseases: report of a NIAID/NHLBI/MeDALL joint workshop.
Bousquet J, Gern JE, Martinez FD, Anto JM, Johnson CC, Holt PG, Lemanske RF Jr, Le Souëf PN, Tepper RS, von Mutius ER, Arshad SH, Bacharier LB, Becker A, Belanger K, Bergström A, Bernstein DI, Cabana MD, Carroll KN, Castro M, Cooper PJ, Gillman MW, Gold DR, Henderson J, Heinrich J, Hong SJ, Jackson DJ, Keil T, Kozyrskyj AL, Lødrup Carlsen KC, Miller RL, Momas I, Morgan WJ, Noel P, Ownby DR, Pinart M, Ryan PH, Schwaninger JM, Sears MR, Simpson A, Smit HA, Stern DA, Subbarao P, Valenta R, Wang X, Weiss ST, Wood R, Wright AL, Wright RJ, Togias A, Gergen PJ
J Allergy Clin Immunol. 2014 Jun; 133(6)1535-46. doi: 10.1016/j.jaci.2014.01.018.

PMID:
    24636091
    [PubMed - indexed for MEDLINE]
Related citations


The Vitamin D Antenatal Asthma Reduction Trial (VDAART): rationale, design, and methods of a randomized, controlled trial of vitamin D supplementation in pregnancy for the primary prevention of asthma and allergies in children.
Litonjua AA, Lange NE, Carey VJ, Brown S, Laranjo N, Harshfield BJ, O'Connor GT, Sandel M, Strunk RC, Bacharier LB, Zeiger RS, Schatz M, Hollis BW, Weiss ST
Contemp Clin Trials. 2014 May; 38(1)37-50. doi: 10.1016/j.cct.2014.02.006.

PMID:
    24614387
    [PubMed - indexed for MEDLINE]
Related citations


Nonrespiratory symptoms before loss of asthma control in children.
Newton LP, Osei-Akosa Y, Strunk RC, Krauss M, Bacharier LB, Garbutt JM, Rivera-Spoljaric K
J Allergy Clin Immunol Pract. 2013 May-Jun; 1(3)304-6.e1-2. doi: 10.1016/j.jaip.2013.01.012.

PMID:
    24565492
    [PubMed - indexed for MEDLINE]
Related citations


The challenge of treating preschool wheezing episodes: the need for evidence-based approaches.
Beigelman A, Zeiger RS, Kelly HW, Bacharier LB, Childhood Asthma Research and Education Network of National Heart, Lung, and Blood Institute
J Allergy Clin Immunol. 2014 Apr; 133(4)1016-7. doi: 10.1016/j.jaci.2014.01.005.

PMID:
    24529412
    [PubMed - indexed for MEDLINE]
Related citations


Early weight gain and the development of asthma and atopy in children.
Wandalsen GF, Chong-Neto HJ, de Souza FS, Solé D, Bacharier LB
Curr Opin Allergy Clin Immunol. 2014 Apr; 14(2)126-30. doi: 10.1097/ACI.0000000000000037.

PMID:
    24451911
    [PubMed - indexed for MEDLINE]
Related citations


The relationships between environmental bacterial exposure, airway bacterial colonization, and asthma.
Beigelman A, Weinstock GM, Bacharier LB
Curr Opin Allergy Clin Immunol. 2014 Apr; 14(2)137-42. doi: 10.1097/ACI.0000000000000036.

PMID:
    24451910
    [PubMed - indexed for MEDLINE]
Related citations


Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma.
Rabinovitch N, Mauger DT, Reisdorph N, Covar R, Malka J, Lemanske RF Jr, Morgan WJ, Guilbert TW, Zeiger RS, Bacharier LB, Szefler SJ
J Allergy Clin Immunol. 2014 Feb; 133(2)350-6. doi: 10.1016/j.jaci.2013.07.039.

PMID:
    24084071
    [PubMed - indexed for MEDLINE]
Related citations


Vitamin D status at birth: an important and potentially modifiable determinant of atopic disease in childhood?
Bacharier LB
J Allergy Clin Immunol. 2014 Jan; 133(1)154-5. doi: 10.1016/j.jaci.2013.07.034.

PMID:
    24001801
    [PubMed - indexed for MEDLINE]
Related citations


Do oral corticosteroids reduce the severity of acute lower respiratory tract illnesses in preschool children with recurrent wheezing?
Beigelman A, King TS, Mauger D, Zeiger RS, Strunk RC, Kelly HW, Martinez FD, Lemanske RF Jr, Rivera-Spoljaric K, Jackson DJ, Guilbert T, Covar R, Bacharier LB, Childhood Asthma Research and Education Network of National Heart, Lung, and Blood Institute
J Allergy Clin Immunol. 2013 Jun; 131(6)1518-25. doi: 10.1016/j.jaci.2013.01.034.

PMID:
    23498594
    [PubMed - indexed for MEDLINE]
Related citations


Clinical and laboratory factors associated with negative oral food challenges.
Beigelman A, Strunk RC, Garbutt JM, Schechtman KB, Jaenicke MW, Stein JS, Bacharier LB
Allergy Asthma Proc. 2012 Nov-Dec; 33(6)467-73. doi: 10.2500/aap.2012.33.3607.

PMID:
    23394503
    [PubMed - indexed for MEDLINE]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2014.

Company Name: DBV Technologies

Royalties:

Equity: No

Consulting/Advisory Board: $10,001 - $25,000

Speaker Fees:

Reporting Date: May 01, 2015

Areas of Research Interest

Dr. Bacharier's research focuses on childhood asthma. Specifically, he is co-principal investigator for the NHBLI’s AsthmaNet, a multi-centered network examining novel therapeutic approaches to asthma in children and adults. He is an investigator in the Childhood Asthma Research and Education (CARE) Network, an NHLBI-funded multi-centered network examining novel therapeutic strategies in children with asthma. He is a co-investigator in the Childhood Asthma Management Program, a multi-centered prospective trial examining the effects of early treatment of asthma on lung growth. He also serves as Co-Principal Investigator of a study examining the role of early infection with Respiratory Syncytial Virus upon the subsequent development of asthma.