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Leonard B. Bacharier, MD

Robert C. Strunk Endowed Chair for Lung and Respiratory Research Professor of Pediatrics
Clinical Director, Division of Allergy, Immunology and Pulmonary Medicine

Specialty Areas

Pediatric Allergy
Pediatric Immunology
Pediatric Asthma

Board Certifications

Allergy & Clinical Immunology
Pediatrics

Hospital Affiliations

St. Louis Children's Hospital

Referral Information

Physician Referral Required

Areas of Clinical Interest

Asthma in children, allergy and lung disease in children, immunology

  • Maps & Directions
  • Education
  • Publication & Research
  • Financial Disclosures

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: Suite C
Floor: 2nd Floor
Office Phone: 314-454-2694

St. Louis Children's Specialty Care Center

13001 North Outer Forty
St. Louis, MO 63017

Suite: 2E
Office Phone: 314-454-2694

Education

Education

Fellowship: Pediatric Allergy and Immunology, Children's Hospital, Boston, Massachusetts
Residency: Pediatrics, St. Louis Children's Hospital, St. Louis, Missouri 1995
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1992
B.S.: Biophysics, The Johns Hopkins University, Baltimore, Maryland

Publication & Research

Publication & Research

Prenatal and Early Life Triclosan and Parabens Exposure and Allergic Outcomes.
Lee-Sarwar K, Hauser R, Calafat AM, Ye X, O'Connor GT, Sandel M, Bacharier LB, Zeiger RS, Laranjo N, Gold DR, Weiss ST, Litonjua AA, Savage JH
J Allergy Clin Immunol. 2017 Oct 27; pii: S0091-6749(17)31652-4. doi: 10.1016/j.jaci.2017.09.029.

PMID:
    29111213
    [PubMed - as supplied by publisher]
Related citations


Early-life home environment and risk of asthma among inner-city children.
O'Connor GT, Lynch SV, Bloomberg GR, Kattan M, Wood RA, Gergen PJ, Jaffee KF, Calatroni A, Bacharier LB, Beigelman A, Sandel MT, Johnson CC, Faruqi A, Santee C, Fujimura KE, Fadrosh D, Boushey H, Visness CM, Gern JE
J Allergy Clin Immunol. 2017 Sep 12; pii: S0091-6749(17)31204-6. doi: 10.1016/j.jaci.2017.06.040.

PMID:
    28939248
    [PubMed - as supplied by publisher]
Related citations


The Association of Maternal Asthma and Early Pregnancy Vitamin D with Risk of Preeclampsia: An Observation From Vitamin D Antenatal Asthma Reduction Trial (VDAART).
Mirzakhani H, Carey VJ, McElrath TF, Laranjo N, O'Connor G, Iverson RE, Lee-Parritz A, Strunk RC, Bacharier LB, Macones GA, Zeiger RS, Schatz M, Hollis BW, Litonjua AA, Weiss ST
J Allergy Clin Immunol Pract. 2017 Sep 8; pii: S2213-2198(17)30543-3. doi: 10.1016/j.jaip.2017.07.018.

PMID:
    28923490
    [PubMed - as supplied by publisher]
Related citations


Screen Time Engagement Is Increased in Urban Children With Asthma.
Rota AP, Bacharier LB, Jaffee K, Visness CM, Kattan M, O'Connor GT, Wood RA, Gergen PJ, Gern JE, Bloomberg GR
Clin Pediatr (Phila). 2017 Oct; 56(11)1048-1053. doi: 10.1177/0009922817698801.

PMID:
    28871879
    [PubMed - indexed for MEDLINE]
Related citations


Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age.
Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, Sorkness RL, Gaston BM, Erzurum SC, Comhair SAA, Myers RE, Zein J, DeBoer MD, Irani AM, Israel E, Levy B, Cardet JC, Phipatanakul W, Gaffin JM, Holguin F, Fajt ML, Aujla SJ, Mauger DT, Jarjour NN
J Allergy Clin Immunol Pract. 2017 Aug 30; pii: S2213-2198(17)30526-3. doi: 10.1016/j.jaip.2017.05.032.

PMID:
    28866107
    [PubMed - as supplied by publisher]
Related citations


Severe Asthma in Children.
Ramratnam SK, Bacharier LB, Guilbert TW
J Allergy Clin Immunol Pract. 2017 Jul - Aug; 5(4)889-898. doi: 10.1016/j.jaip.2017.04.031.

PMID:
    28689839
    [PubMed - in process]
Related citations


A prospective microbiome-wide association study of food sensitization and food allergy in early childhood.
Savage JH, Lee-Sarwar KA, Sordillo J, Bunyavanich S, Zhou Y, O'Connor G, Sandel M, Bacharier LB, Zeiger R, Sodergren E, Weinstock GM, Gold DR, Weiss ST, Litonjua AA
Allergy. 2017 Jun 20; doi: 10.1111/all.13232.

PMID:
    28632934
    [PubMed - as supplied by publisher]
Related citations


Asthma control status in pregnancy, body mass index, and maternal vitamin D levels.
Mirzakhani H, O'Connor G, Bacharier LB, Zeiger RS, Schatz MX, Weiss ST, Litonjua AA
J Allergy Clin Immunol. 2017 Nov; 140(5)1453-1456.e7. doi: 10.1016/j.jaci.2017.03.053.

PMID:
    28606587
    [PubMed - in process]
Related citations


Microbes and the Role of Antibiotic Treatment for Wheezy Lower Respiratory Tract Illnesses in Preschool Children.
Kwong CG, Bacharier LB
Curr Allergy Asthma Rep. 2017 May; 17(5)34. doi: 10.1007/s11882-017-0701-6.

PMID:
    28456910
    [PubMed - indexed for MEDLINE]
Related citations


BMAL1 links the circadian clock to viral airway pathology and asthma phenotypes.
Ehlers A, Xie W, Agapov E, Brown S, Steinberg D, Tidwell R, Sajol G, Schutz R, Weaver R, Yu H, Castro M, Bacharier LB, Wang X, Holtzman MJ, Haspel JA
Mucosal Immunol. 2017 Apr 12; doi: 10.1038/mi.2017.24.

PMID:
    28401936
    [PubMed - as supplied by publisher]
Related citations


Vitamin D supplementation in pregnancy, prenatal 25(OH)D levels, race, and subsequent asthma or recurrent wheeze in offspring: Secondary analyses from the Vitamin D Antenatal Asthma Reduction Trial.
Wolsk HM, Harshfield BJ, Laranjo N, Carey VJ, O'Connor G, Sandel M, Strunk RC, Bacharier LB, Zeiger RS, Schatz M, Hollis BW, Weiss ST, Litonjua AA
J Allergy Clin Immunol. 2017 Nov; 140(5)1423-1429.e5. doi: 10.1016/j.jaci.2017.01.013.

PMID:
    28285844
    [PubMed - in process]
Related citations


Reducing Exposure to Mouse Allergen Among Children and Adolescents With Asthma Is Achievable, but Is It Enough?
Bacharier LB
JAMA. 2017 Mar 14; 317(10)1023-1025. doi: 10.1001/jama.2016.21181.

PMID:
    28264092
    [PubMed - indexed for MEDLINE]
Related citations


Pediatric asthma - moving ahead faster than ever.
Bacharier LB, Szefler SJ
Curr Opin Allergy Clin Immunol. 2017 Apr; 17(2)96-98. doi: 10.1097/ACI.0000000000000353.

PMID:
    28225363
    [PubMed - in process]
Related citations


Editorial: moving ahead faster than ever.
Bacharier LB, Szefler SJ
Curr Opin Allergy Clin Immunol. 2017 Jan 30; doi: 10.1097/ACI.0000000000000353.

PMID:
    28141627
    [PubMed - as supplied by publisher]
Related citations


Management of preschool recurrent wheezing and asthma: a phenotype-based approach.
Beigelman A, Bacharier LB
Curr Opin Allergy Clin Immunol. 2017 Apr; 17(2)131-138. doi: 10.1097/ACI.0000000000000344.

PMID:
    28118241
    [PubMed - indexed for MEDLINE]
Related citations


Patterns of immune development in urban preschoolers with recurrent wheeze and/or atopy.
Gern JE, Calatroni A, Jaffee KF, Lynn H, Dresen A, Cruikshank WW, Lederman HM, Sampson HA, Shreffler W, Bacharier LB, Gergen PJ, Gold DR, Kattan M, O'Connor GT, Sandel MT, Wood RA, Bloomberg GR
J Allergy Clin Immunol. 2017 Sep; 140(3)836-844.e7. doi: 10.1016/j.jaci.2016.10.052.

PMID:
    28089873
    [PubMed - indexed for MEDLINE]
Related citations


Strategies to alter the natural history of childhood asthma.
Lee-Sarwar KA, Bacharier LB, Litonjua AA
Curr Opin Allergy Clin Immunol. 2017 Apr; 17(2)139-145. doi: 10.1097/ACI.0000000000000340.

PMID:
    28079559
    [PubMed - indexed for MEDLINE]
Related citations


Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma.
Phipatanakul W, Mauger DT, Sorkness RL, Gaffin JM, Holguin F, Woodruff PG, Ly NP, Bacharier LB, Bhakta NR, Moore WC, Bleecker ER, Hastie AT, Meyers DA, Castro M, Fahy JV, Fitzpatrick AM, Gaston BM, Jarjour NN, Levy BD, Peters SP, Teague WG, Fajt M, Wenzel SE, Erzurum SC, Israel E, Severe Asthma Research Program.
Am J Respir Crit Care Med. 2017 Jun 1; 195(11)1439-1448. doi: 10.1164/rccm.201607-1453OC.

PMID:
    27967215
    [PubMed - indexed for MEDLINE]
Related citations


Individualized therapy for persistent asthma in young children.
Fitzpatrick AM, Jackson DJ, Mauger DT, Boehmer SJ, Phipatanakul W, Sheehan WJ, Moy JN, Paul IM, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan W, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Szefler SJ, NIH/NHLBI AsthmaNet.
J Allergy Clin Immunol. 2016 Dec; 138(6)1608-1618.e12. doi: 10.1016/j.jaci.2016.09.028.

PMID:
    27777180
    [PubMed - indexed for MEDLINE]
Related citations


Distinguishing characteristics of difficult-to-control asthma in inner-city children and adolescents.
Pongracic JA, Krouse RZ, Babineau DC, Zoratti EM, Cohen RT, Wood RA, Khurana Hershey GK, Kercsmar CM, Gruchalla RS, Kattan M, Teach SJ, Johnson CC, Bacharier LB, Gern JE, Sigelman SM, Gergen PJ, Togias A, Visness CM, Busse WW, Liu AH
J Allergy Clin Immunol. 2016 Oct; 138(4)1030-1041. doi: 10.1016/j.jaci.2016.06.059.

PMID:
    27720017
    [PubMed - indexed for MEDLINE]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2016.

Company Name: Boehringer Ingelheim

Royalties:

Equity: No

Consulting/Advisory Board: $1,000 - $10,000

Speaker Fees: $1,000 - $10,000

Reporting Date: May 01, 2017


Company Name: Teva

Royalties:

Equity: No

Consulting/Advisory Board: $1,000 - $10,000

Speaker Fees: $10,001 - $25,000

Reporting Date: May 01, 2017

Areas of Research Interest

Dr. Bacharier's research focuses on childhood asthma. Specifically, he is co-principal investigator for the NHBLI’s AsthmaNet, a multi-centered network examining novel therapeutic approaches to asthma in children and adults. He is an investigator in the Childhood Asthma Research and Education (CARE) Network, an NHLBI-funded multi-centered network examining novel therapeutic strategies in children with asthma. He is a co-investigator in the Childhood Asthma Management Program, a multi-centered prospective trial examining the effects of early treatment of asthma on lung growth. He also serves as Co-Principal Investigator of a study examining the role of early infection with Respiratory Syncytial Virus upon the subsequent development of asthma.