Patient Portal

Lee Ratner, MD, PhD

Professor, Medicine
Division of Oncology
Section, Medical Oncology
Professor, Pathology
Professor, Microbiology

Specialty Areas

Oncology
Medical Oncology
Hematology
Sarcoma

Board Certifications

Internal Medicine
Oncology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

HIV, AIDS, human immunodeficiency virus, hematology, oncology, AIDS-related malignancies

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

Center for Advanced Medicine
Siteman Cancer Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 7
Office Phone: 314-362-7578
Fax: 314-747-2120

Education

Education

Fellowship: Oncology, National Cancer Institute, NIH, Bethesda, Maryland 1985
Residency: Internal Medicine, Washington Univ School of Medicine, Barnes-Jewish Hospital, St. Louis, Missouri 1982
Medical Degree, PhD: Yale University School of Medicine, New Haven, Connecticut 1979
B.A., M.A.: Chemistry, Harvard University, Cambridge, Massachusetts 1973

Publication & Research

Publication & Research

Dynamic host immune response in virus-associated cancers.
Cao S, Wylie KM, Wyczalkowski MA, Karpova A, Ley J, Sun S, Mashl RJ, Liang WW, Wang X, Johnson K, DiPersio JF, Gay H, Ratner L, Chen F, Adkins DR, Ding L
Commun Biol. 2019; 2109. doi: 10.1038/s42003-019-0352-3.

PMID:
    30911684
    [PubMed]
Related citations


HTLV-1 Tax-1 interacts with SNX27 to regulate cellular localization of the HTLV-1 receptor molecule, GLUT1.
Al-Saleem J, Dirksen WP, Martinez MP, Shkriabai N, Kvaratskhelia M, Ratner L, Green PL
PLoS One. 2019; 14(3)e0214059. doi: 10.1371/journal.pone.0214059.

PMID:
    30897179
    [PubMed - in process]
Related citations


Safety and efficacy of eculizumab in the prevention of antibody-mediated rejection in living-donor kidney transplant recipients requiring desensitization therapy: A randomized trial.
Marks WH, Mamode N, Montgomery R, Stegall MD, Ratner LE, Cornell LD, Rowshani AT, Colvin RB, Dain B, Boice JA, Glotz D, C10-001 Study Group.
Am J Transplant. 2019 Mar 19; doi: 10.1111/ajt.15364.

PMID:
    30887675
    [PubMed - as supplied by publisher]
Related citations


V1 and V2 Domains of HIV Envelope Contribute to CCR5 Antagonist Resistance.
Wu E, Du Y, Gao X, Zhang J, Martin J, Mitreva M, Ratner L
J Virol. 2019 May 1; 93(9)pii: e00050-19. doi: 10.1128/JVI.00050-19.

PMID:
    30787151
    [PubMed - in process]
Related citations


AIDS-Related Kaposi Sarcoma, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology.
Reid E, Suneja G, Ambinder RF, Ard K, Baiocchi R, Barta SK, Carchman E, Cohen A, Crysler OV, Gupta N, Gustafson C, Hall A, Johung KL, Klopp A, LaCasce AS, Lin C, Mehta A, Menon MP, Morgan D, Nathwani N, Noy A, Ratner L, Rizza S, Rudek MA, Sanchez J, Taylor J, Tomlinson B, Wang CJ, Yendamuri S, Dwyer MA, CGC., Freedman-Cass DA
J Natl Compr Canc Netw. 2019 Feb; 17(2)171-189. doi: 10.6004/jnccn.2019.0008.

PMID:
    30787130
    [PubMed - in process]
Related citations


Bariatric surgery prior to living donor nephrectomy: a solution to expand the living donor kidney pool - a retrospective study.
Nguyen MJP, Carpenter D, Tadros J, Mathur A, Sandoval PR, Woodle ES, Diwan T, Ratner LE
Transpl Int. 2019 Feb 5; doi: 10.1111/tri.13408.

PMID:
    30721545
    [PubMed - as supplied by publisher]
Related citations


Chylous ascites following laparoscopic live donor nephrectomy: A new improved treatment paradigm.
Dale LA, Sandoval PR, Ratner LE
Clin Transplant. 2019 Mar; 33(3)e13483. doi: 10.1111/ctr.13483.

PMID:
    30661276
    [PubMed - in process]
Related citations


Revised Adult T-Cell Leukemia-Lymphoma International Consensus Meeting Report.
Cook LB, Fuji S, Hermine O, Bazarbachi A, Ramos JC, Ratner L, Horwitz S, Fields P, Tanase A, Bumbea H, Cwynarski K, Taylor G, Waldmann TA, Bittencourt A, Marcais A, Suarez F, Sibon D, Phillips A, Lunning M, Farid R, Imaizumi Y, Choi I, Ishida T, Ishitsuka K, Fukushima T, Uchimaru K, Takaori-Kondo A, Tokura Y, Utsunomiya A, Matsuoka M, Tsukasaki K, Watanabe T
J Clin Oncol. 2019 Mar 10; 37(8)677-687. doi: 10.1200/JCO.18.00501.

PMID:
    30657736
    [PubMed - in process]
Related citations


Deceased brain dead donor liver transplantation and utilization in the United States: nighttime and weekend effects.
Carpenter DJ, Chiles MC, Verna EC, Halazun KJ, Emond JC, Ratner LE, Mohan S
Transplantation. 2018 Nov 15; doi: 10.1097/TP.0000000000002533.

PMID:
    30444802
    [PubMed - as supplied by publisher]
Related citations


Splicing Factor 3B Subunit 1 Interacts with HIV Tat and Plays a Role in Viral Transcription and Reactivation from Latency.
Kyei GB, Meng S, Ramani R, Niu A, Lagisetti C, Webb TR, Ratner L
MBio. 2018 Nov 6; 9(6)pii: e01423-18. doi: 10.1128/mBio.01423-18.

PMID:
    30401776
    [PubMed - in process]
Related citations


Procurement Biopsies in the Evaluation of Deceased Donor Kidneys.
Carpenter D, Husain SA, Brennan C, Batal I, Hall IE, Santoriello D, Rosen R, Crew RJ, Campenot E, Dube GK, Radhakrishnan J, Stokes MB, Sandoval PR, D'Agati V, Cohen DJ, Ratner LE, Markowitz G, Mohan S
Clin J Am Soc Nephrol. 2018 Dec 7; 13(12)1876-1885. doi: 10.2215/CJN.04150418.

PMID:
    30361336
    [PubMed - in process]
Related citations


Outcomes for potential kidney transplant recipients offered public health service increased risk kidneys: A single-center experience.
Fernandez HE, Chiles MC, Pereira M, Husain SA, Miko B, Baral P, Dale LA, Patel S, Runge B, Tsapepas D, Sandoval PR, Ratner LE, Cohen DJ, Mohan S
Clin Transplant. 2018 Dec; 32(12)e13427. doi: 10.1111/ctr.13427.

PMID:
    30329179
    [PubMed - in process]
Related citations


Programming of the reproductive axis by hormonal and genetic manipulation in mice
Rulli SB, Cambiasso MJ, Ratner LD
Reproduction. 2018 Oct 1; 156(4)R101–R109. doi: 10.1530/REP-18-0054.

PMID:
    30304933
    [PubMed - in process]
Related citations


Pathology of Calcineurin and Mammalian Target of Rapamycin Inhibitors in Kidney Transplantation.
Leal R, Tsapepas D, Crew RJ, Dube GK, Ratner L, Batal I
Kidney Int Rep. 2018 Mar; 3(2)281-290. doi: 10.1016/j.ekir.2017.10.010.

PMID:
    30276344
    [PubMed]
Related citations


Association between the "Timed Up and Go Test" at transplant evaluation and outcomes after kidney transplantation.
Michelson AT, Tsapepas DS, Husain SA, Brennan C, Chiles MC, Runge B, Lione J, Kil BH, Cohen DJ, Ratner LE, Mohan S
Clin Transplant. 2018 Nov; 32(11)e13410. doi: 10.1111/ctr.13410.

PMID:
    30230036
    [PubMed - in process]
Related citations


PD-1 Inhibitor Therapy in Adult T-Cell Leukemia-Lymphoma.
Ratner L, the Authors.
N Engl J Med. 2018 Aug 16; 379(7)696-697. doi: 10.1056/NEJMc1807852.

PMID:
    30110590
    [PubMed - indexed for MEDLINE]
Related citations


North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies.
Shah UA, Chung EY, Giricz O, Pradhan K, Kataoka K, Gordon-Mitchell S, Bhagat TD, Mai Y, Wei Y, Ishida E, Choudhary GS, Joseph A, Rice R, Gitego N, Parrish C, Bartenstein M, Goel S, Mantzaris I, Shastri A, Derman O, Binder A, Gritsman K, Kornblum N, Braunschweig I, Bhagat C, Hall J, Graber A, Ratner L, Wang Y, Ogawa S, Verma A, Ye BH, Janakiram M
Blood. 2018 Oct 4; 132(14)1507-1518. doi: 10.1182/blood-2018-01-824607.

PMID:
    30104217
    [PubMed - in process]
Related citations


Cancer in People Living With HIV, Version 1.2018, NCCN Clinical Practice Guidelines in Oncology.
Reid E, Suneja G, Ambinder RF, Ard K, Baiocchi R, Barta SK, Carchman E, Cohen A, Gupta N, Johung KL, Klopp A, LaCasce AS, Lin C, Makarova-Rusher OV, Mehta A, Menon MP, Morgan D, Nathwani N, Noy A, Palella F, Ratner L, Rizza S, Rudek MA, Taylor J, Tomlinson B, Wang CJ, Dwyer MA, Freedman-Cass DA
J Natl Compr Canc Netw. 2018 Aug; 16(8)986-1017. doi: 10.6004/jnccn.2018.0066.

PMID:
    30099375
    [PubMed - in process]
Related citations


Effect of Primary Tumor Side on Survival Outcomes in Untreated Patients With Metastatic Colorectal Cancer When Selective Internal Radiation Therapy Is Added to Chemotherapy: Combined Analysis of Two Randomized Controlled Studies.
Gibbs P, Heinemann V, Sharma NK, Taieb J, Ricke J, Peeters M, Findlay M, Robinson B, Jackson C, Strickland A, Gebski V, Van Buskirk M, Zhao H, van Hazel G, SIRFLOX and FOXFIRE Global Trial Investigators.
Clin Colorectal Cancer. 2018 Dec; 17(4)e617-e629. doi: 10.1016/j.clcc.2018.06.001.

PMID:
    30033117
    [PubMed - in process]
Related citations


Programming of the reproductive axis by hormonal and genetic manipulation in mice.
Rulli SB, Cambiasso MJ, Ratner LD
Reproduction. 2018 Jun 25; pii: REP-18-0054. doi: 10.1530/REP-18-0054.

PMID:
    29941464
    [PubMed - as supplied by publisher]
Related citations