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Faculty Physicians

Lawrence N. Eisenman, MD, PhD

Associate Professor, Neurology
Adult Epilepsy Center

Specialty Areas

Neurophysiology
EEG
Epilepsy
Neurology - Adult

Board Certifications

Neurology
Epilepsy
Clinical Neurophysiology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Epilepsy and seizures, surgical evaluation and treatment of refractory epilepsy.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Neuroscience Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: (314) 362-7845
Fax: (314) 362-0296

Education

Education

Fellowship: Epilepsy and Neurophysiology, Washington University School of Medicine, St. Louis, Missouri 2003
Residency: Neurology, Washington University School of Medicine, St. Louis, Missouri 2001
PhD: Physiology, Northwestern University Medical School, Chicago, Illinois 1997
Medical Degree: Northwestern University Medical School, Chicago, Illinois 1997
Bachelor of Science: Biomedical Engineering, The Johns Hopkins University, Baltimore, Maryland 1988

Publication & Research

Publication & Research

Quantification of bursting and synchrony in cultured hippocampal neurons.
Eisenman LN, Emnett CM, Mohan J, Zorumski CF, Mennerick S
J Neurophysiol. 2015 Aug; 114(2)1059-71. doi: 10.1152/jn.00079.2015.

PMID:
    26041823
    [PubMed - in process]
Related citations


24(S)-Hydroxycholesterol as a Modulator of Neuronal Signaling and Survival.
Sun MY, Linsenbardt AJ, Emnett CM, Eisenman LN, Izumi Y, Zorumski CF, Mennerick S
Neuroscientist. 2015 Jan 27; pii: 1073858414568122.

PMID:
    25628343
    [PubMed - as supplied by publisher]
Related citations


Interaction between positive allosteric modulators and trapping blockers of the NMDA receptor channel.
Emnett CM, Eisenman LN, Mohan J, Taylor AA, Doherty JJ, Paul SM, Zorumski CF, Mennerick S
Br J Pharmacol. 2015 Mar; 172(5)1333-47. doi: 10.1111/bph.13007.

PMID:
    25377730
    [PubMed - in process]
Related citations


Indistinguishable synaptic pharmacodynamics of the N-methyl-D-aspartate receptor channel blockers memantine and ketamine.
Emnett CM, Eisenman LN, Taylor AM, Izumi Y, Zorumski CF, Mennerick S
Mol Pharmacol. 2013 Dec; 84(6)935-47. doi: 10.1124/mol.113.089334.

PMID:
    24101301
    [PubMed - indexed for MEDLINE]
Related citations


Impaired and facilitated functional networks in temporal lobe epilepsy.
Maccotta L, He BJ, Snyder AZ, Eisenman LN, Benzinger TL, Ances BM, Corbetta M, Hogan RE
Neuroimage Clin. 2013; 2862-72. doi: 10.1016/j.nicl.2013.06.011.

PMID:
    24073391
    [PubMed]
Related citations


Trans-middle temporal gyrus selective amygdalohippocampectomy for medically intractable mesial temporal lobe epilepsy in adults: seizure response rates, complications, and neuropsychological outcomes.
Bandt SK, Werner N, Dines J, Rashid S, Eisenman LN, Hogan RE, Leuthardt EC, Dowling J
Epilepsy Behav. 2013 Jul; 28(1)17-21. doi: 10.1016/j.yebeh.2013.03.020.

PMID:
    23648275
    [PubMed - indexed for MEDLINE]
Related citations


Mapping sensorimotor cortex with slow cortical potential resting-state networks while awake and under anesthesia.
Breshears JD, Gaona CM, Roland JL, Sharma M, Bundy DT, Shimony JS, Rashid S, Eisenman LN, Hogan RE, Snyder AZ, Leuthardt EC
Neurosurgery. 2012 Aug; 71(2)305-16; discussion 316. doi: 10.1227/NEU.0b013e318258e5d1.

PMID:
    22517255
    [PubMed - indexed for MEDLINE]
Related citations


Magnesium induces neuronal apoptosis by suppressing excitability.
Dribben WH, Eisenman LN, Mennerick S
Cell Death Dis. 2010 Aug 12; 1e63. doi: 10.1038/cddis.2010.39.

PMID:
    21364668
    [PubMed - indexed for MEDLINE]
Related citations


Differential effects of axon initial segment and somatodendritic GABAA receptors on excitability measures in rat dentate granule neurons.
Rojas P, Akrouh A, Eisenman LN, Mennerick S
J Neurophysiol. 2011 Jan; 105(1)366-79. doi: 10.1152/jn.00165.2010.

PMID:
    21068264
    [PubMed - indexed for MEDLINE]
Related citations


The sticky issue of neurosteroids and GABA(A) receptors.
Chisari M, Eisenman LN, Covey DF, Mennerick S, Zorumski CF
Trends Neurosci. 2010 Jul; 33(7)299-306. doi: 10.1016/j.tins.2010.03.005.

PMID:
    20409596
    [PubMed - indexed for MEDLINE]
Related citations


Diverse voltage-sensitive dyes modulate GABAA receptor function.
Mennerick S, Chisari M, Shu HJ, Taylor A, Vasek M, Eisenman LN, Zorumski CF
J Neurosci. 2010 Feb 24; 30(8)2871-9. doi: 10.1523/JNEUROSCI.5607-09.2010.

PMID:
    20181584
    [PubMed - indexed for MEDLINE]
Related citations


Axonal sodium channel distribution shapes the depolarized action potential threshold of dentate granule neurons.
Kress GJ, Dowling MJ, Eisenman LN, Mennerick S
Hippocampus. 2010 Apr; 20(4)558-71. doi: 10.1002/hipo.20667.

PMID:
    19603521
    [PubMed - indexed for MEDLINE]
Related citations


Photodynamic effects of steroid-conjugated fluorophores on GABAA receptors.
Shu HJ, Eisenman LN, Wang C, Bandyopadhyaya AK, Krishnan K, Taylor A, Benz AM, Manion B, Evers AS, Covey DF, Zorumski CF, Mennerick S
Mol Pharmacol. 2009 Oct; 76(4)754-65. doi: 10.1124/mol.109.057687.

PMID:
    19596835
    [PubMed - indexed for MEDLINE]
Related citations


The influence of neuroactive steroid lipophilicity on GABAA receptor modulation: evidence for a low-affinity interaction.
Chisari M, Eisenman LN, Krishnan K, Bandyopadhyaya AK, Wang C, Taylor A, Benz A, Covey DF, Zorumski CF, Mennerick S
J Neurophysiol. 2009 Aug; 102(2)1254-64. doi: 10.1152/jn.00346.2009.

PMID:
    19553485
    [PubMed - indexed for MEDLINE]
Related citations


NMDA potentiation by visible light in the presence of a fluorescent neurosteroid analogue.
Eisenman LN, Shu HJ, Wang C, Aizenman E, Covey DF, Zorumski CF, Mennerick S
J Physiol. 2009 Jun 15; 587(Pt 12)2937-47. doi: 10.1113/jphysiol.2009.172700.

PMID:
    19403611
    [PubMed - indexed for MEDLINE]
Related citations


Effects on membrane capacitance of steroids with antagonist properties at GABAA receptors.
Mennerick S, Lamberta M, Shu HJ, Hogins J, Wang C, Covey DF, Eisenman LN, Zorumski CF
Biophys J. 2008 Jul; 95(1)176-85. doi: 10.1529/biophysj.107.124768.

PMID:
    18339741
    [PubMed - indexed for MEDLINE]
Related citations


Anticonvulsant and anesthetic effects of a fluorescent neurosteroid analog activated by visible light.
Eisenman LN, Shu HJ, Akk G, Wang C, Manion BD, Kress GJ, Evers AS, Steinbach JH, Covey DF, Zorumski CF, Mennerick S
Nat Neurosci. 2007 Apr; 10(4)523-30.

PMID:
    17322875
    [PubMed - indexed for MEDLINE]
Related citations


A spontaneous tonic chloride conductance in solitary glutamatergic hippocampal neurons.
Eisenman LN, Kress G, Zorumski CF, Mennerick S
Brain Res. 2006 Nov 6; 1118(1)66-74.

PMID:
    16987500
    [PubMed - indexed for MEDLINE]
Related citations


Self-reported seizure frequency and time to first event in the seizure monitoring unit.
Eisenman LN, Attarian H, Fessler AJ, Vahle VJ, Gilliam F
Epilepsia. 2005 May; 46(5)664-8.

PMID:
    15857431
    [PubMed - indexed for MEDLINE]
Related citations


Slow actions of neuroactive steroids at GABAA receptors.
Shu HJ, Eisenman LN, Jinadasa D, Covey DF, Zorumski CF, Mennerick S
J Neurosci. 2004 Jul 28; 24(30)6667-75.

PMID:
    15282269
    [PubMed - indexed for MEDLINE]
Related citations